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Research ArticleCELLULAR AND MOLECULAR

Role of Multidrug Resistance Protein 2 (MRP2, ABCC2) in Alkylating Agent Detoxification: MRP2 Potentiates Glutathione S-Transferase A1-1-Mediated Resistance to Chlorambucil Cytotoxicity

Pamela K. Smitherman, Alan J. Townsend, Timothy E. Kute and Charles S. Morrow
Journal of Pharmacology and Experimental Therapeutics January 2004, 308 (1) 260-267; DOI: https://doi.org/10.1124/jpet.103.057729

Article Information

vol. 308 no. 1 260-267
DOI 
https://doi.org/10.1124/jpet.103.057729
PubMed 
14569069
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received July 28, 2003
  • Accepted September 18, 2003
  • Published online January 7, 2004.

Article Versions

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Pamela K. Smitherman,
  2. Alan J. Townsend,
  3. Timothy E. Kute and
  4. Charles S. Morrow
  1. Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, North Carolina (P.K.S., A.J.T., C.S.M.); and Department of Pathology, Wake Forest University School of Medicine, Winston-Salem, North Carolina (T.E.K.)
  1. Address correspondence to:
    Dr. Charles S. Morrow, Department of Biochemistry, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157. E-mail: cmorrow{at}wfubmc.edu
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Research ArticleCELLULAR AND MOLECULAR

Role of Multidrug Resistance Protein 2 (MRP2, ABCC2) in Alkylating Agent Detoxification: MRP2 Potentiates Glutathione S-Transferase A1-1-Mediated Resistance to Chlorambucil Cytotoxicity

Pamela K. Smitherman, Alan J. Townsend, Timothy E. Kute and Charles S. Morrow
Journal of Pharmacology and Experimental Therapeutics January 1, 2004, 308 (1) 260-267; DOI: https://doi.org/10.1124/jpet.103.057729
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