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Research ArticleABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

CYP3A4-Transfected Caco-2 Cells as a Tool for Understanding Biochemical Absorption Barriers: Studies with Sirolimus and Midazolam

Carolyn L. Cummins, Wolfgang Jacobsen, Uwe Christians and Leslie Z. Benet
Journal of Pharmacology and Experimental Therapeutics January 2004, 308 (1) 143-155; DOI: https://doi.org/10.1124/jpet.103.058065

Article Information

vol. 308 no. 1 143-155
DOI 
https://doi.org/10.1124/jpet.103.058065
PubMed 
14569063
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received August 6, 2003
  • Accepted October 8, 2003
  • Published online January 7, 2004.

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Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Carolyn L. Cummins1,
  2. Wolfgang Jacobsen2,
  3. Uwe Christians3 and
  4. Leslie Z. Benet
  1. Department of Biopharmaceutical Sciences, University of California San Francisco, San Francisco, California
  1. Address correspondence to:
    Dr. Leslie Z. Benet, Biopharmaceutical Sciences, University of California San Francisco, 533 Parnassus Ave. U-68, San Francisco, CA 94143-0446. E-mail: benet{at}itsa.ucsf.edu
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Research ArticleABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

CYP3A4-Transfected Caco-2 Cells as a Tool for Understanding Biochemical Absorption Barriers: Studies with Sirolimus and Midazolam

Carolyn L. Cummins, Wolfgang Jacobsen, Uwe Christians and Leslie Z. Benet
Journal of Pharmacology and Experimental Therapeutics January 1, 2004, 308 (1) 143-155; DOI: https://doi.org/10.1124/jpet.103.058065
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