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Research ArticlePERSPECTIVES IN PHARMACOLOGY

Protease-Activated Receptors: New Concepts in Regulation of G Protein-Coupled Receptor Signaling and Trafficking

Joann Trejo
Journal of Pharmacology and Experimental Therapeutics November 2003, 307 (2) 437-442; DOI: https://doi.org/10.1124/jpet.103.052100
Joann Trejo
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Article Information

vol. 307 no. 2 437-442
DOI 
https://doi.org/10.1124/jpet.103.052100
PubMed 
12966163

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received May 7, 2003
  • Accepted July 2, 2003
  • Published online October 21, 2003.

Article Versions

  • Earlier version (September 9, 2003 - 14:24).
  • You are viewing the most recent version of this article.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Joann Trejo
  1. Department of Pharmacology, Cardiovascular Biology Center, Lineberger Comprehensive Cancer Center, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
  1. Address correspondence to:
    JoAnn Trejo, Ph.D., University of North Carolina at Chapel Hill, Department of Pharmacology, 1106 Mary Ellen Jones Bldg., CB #7365, Chapel Hill, NC 27599-7365. E-mail: joann_trejo{at}med.unc.edu
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Journal of Pharmacology and Experimental Therapeutics: 307 (2)
Journal of Pharmacology and Experimental Therapeutics
Vol. 307, Issue 2
1 Nov 2003
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Research ArticlePERSPECTIVES IN PHARMACOLOGY

Protease-Activated Receptors: New Concepts in Regulation of G Protein-Coupled Receptor Signaling and Trafficking

Joann Trejo
Journal of Pharmacology and Experimental Therapeutics November 1, 2003, 307 (2) 437-442; DOI: https://doi.org/10.1124/jpet.103.052100

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Research ArticlePERSPECTIVES IN PHARMACOLOGY

Protease-Activated Receptors: New Concepts in Regulation of G Protein-Coupled Receptor Signaling and Trafficking

Joann Trejo
Journal of Pharmacology and Experimental Therapeutics November 1, 2003, 307 (2) 437-442; DOI: https://doi.org/10.1124/jpet.103.052100
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  • Article
    • Abstract
    • Family of PARs
    • PAR Activation and G Protein Signaling
    • G Protein-Coupled Receptor Kinase (GRK)-Mediated PAR Signal Regulation
    • β Arrestins and PAR Signaling
    • Internalization of PARs
    • Down-Regulation of PARs
    • Inhibitors of PAR Signaling
    • Acknowledgments
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