Journal of Pharmacology and Experimental Therapeutics: 306 (2)

August 01, 2003; Volume 306,Issue 2

PERSPECTIVES IN PHARMACOLOGY

You have access
Nociceptin/Orphanin FQ and Its Receptor—Potential Targets for Pain Therapy?
Hanns Ulrich Zeilhofer and Girolamo Calò

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 423-429; DOI: https://doi.org/10.1124/jpet.102.046979

ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

You have access
A Differential Pharmacokinetic Analysis of the Erythropoietin Receptor Population in Newborn and Adult Sheep
P. Veng-Pedersen, S. Chapel, N. H. Al-Huniti, R. L. Schmidt, E. M. Sedars, R. J. Hohl and J. A. Widness

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 532-537; DOI: https://doi.org/10.1124/jpet.103.052431
You have access
Modulation of P-glycoprotein Transport Activity in the Mouse Blood-Brain Barrier by Rifampin
Jian Zong and Gary M. Pollack

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 556-562; DOI: https://doi.org/10.1124/jpet.103.049452
You have access
Functional Characterization of Human UDP-Glucuronosyltransferase 1A9 Variant, D256N, Found in Japanese Cancer Patients
Hideto Jinno, Mayumi Saeki, Yoshiro Saito, Toshiko Tanaka-Kagawa, Nobumitsu Hanioka, Kimie Sai, Nahoko Kaniwa, Masanori Ando, Kuniaki Shirao, Hironobu Minami, Atsushi Ohtsu, Teruhiko Yoshida, Nagahiro Saijo, Shogo Ozawa and Jun-ichi Sawada

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 688-693; DOI: https://doi.org/10.1124/jpet.103.051250
You have access
Involvement of Human Organic Anion Transporting Polypeptide OATP-B (SLC21A9) in pH-Dependent Transport across Intestinal Apical Membrane
Daisuke Kobayashi, Takashi Nozawa, Kozue Imai, Jun-ichi Nezu, Akira Tsuji and Ikumi Tamai

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 703-708; DOI: https://doi.org/10.1124/jpet.103.051300
You have access
Threonine-205 in the F Helix of P450 2B1 Contributes to Androgen 16β-Hydroxylation Activity and Mechanism-Based Inactivation
Hsia-Lien Lin, Haoming Zhang, Lucy Waskell and Paul F. Hollenberg

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 744-751; DOI: https://doi.org/10.1124/jpet.103.050260
You have access
Gene Expression in the Human Intestine and Correlation with Oral Valacyclovir Pharmacokinetic Parameters
Christopher P. Landowski, Duxin Sun, David R. Foster, Sujatha S. Menon, Jeffrey L. Barnett, Lynda S. Welage, Chandrasekharan Ramachandran and Gordon L. Amidon

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 778-786; DOI: https://doi.org/10.1124/jpet.103.051011

BEHAVIORAL PHARMACOLOGY

You have access
Allodynia and Hyperalgesia in Adjuvant-Induced Arthritic Rats: Time Course of Progression and Efficacy of Analgesics
Yukinori Nagakura, Masamichi Okada, Atsuyuki Kohara, Tetsuo Kiso, Takashi Toya, Akihiko Iwai, Fumikazu Wanibuchi and Tokio Yamaguchi

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 490-497; DOI: https://doi.org/10.1124/jpet.103.050781
You have access
Continuous Administration of the 5-Hydroxytryptamine_1A Agonist (3-Chloro-4-fluoro-phenyl)-[4-fluoro-4-{[(5-methyl-pyridin-2-ylmethyl) -amino]-methyl}piperidin-1-yl]-methadone (F 13640) Attenuates Allodynia-Like Behavior in a Rat Model of Trigeminal Neuropathic Pain
Kristof Deseure, Wouter Koek, Hugo Adriaensen and Francis C. Colpaert

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 505-514; DOI: https://doi.org/10.1124/jpet.103.050286
You have access
Inhibition of Microglial Activation Attenuates the Development but Not Existing Hypersensitivity in a Rat Model of Neuropathy
Vasudeva Raghavendra, Flobert Tanga and Joyce A. DeLeo

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 624-630; DOI: https://doi.org/10.1124/jpet.103.052407

CARDIOVASCULAR

You have access
Muscarinic Cholinergic and β-Adrenergic Contribution to Hindquarters Vasodilation and Cardiac Responses to Cocaine
Mark M. Knuepfer

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 515-522; DOI: https://doi.org/10.1124/jpet.103.051177
You have access
Evidence for a Ceiling of Cardioprotection with a Nitric Oxide Donor-Induced Delayed Preconditioning in Rabbits
Renaud Tissier, Karim Aouam, Alain Berdeaux and Bijan Ghaleh

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 528-531; DOI: https://doi.org/10.1124/jpet.103.052563
You have access
Effects of in Vivo Lipopolysaccharide Infusion on Vasoconstrictor Function of Rat Isolated Mesentery, Kidney, and Aorta
Matthew R. Farmer, Richard E. Roberts, Sheila M. Gardiner and Vera Ralevic

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 538-545; DOI: https://doi.org/10.1124/jpet.103.051805
You have access
Interleukin-2 Increases Activity of Sarcoplasmic Reticulum Ca²⁺-ATPase, but Decreases Its Sensitivity to Calcium in Rat Cardiomyocytes
Chun-Mei Cao, Qiang Xia, Iain C. Bruce, Xiong Zhang, Chen Fu and Jun-Zhu Chen

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 572-580; DOI: https://doi.org/10.1124/jpet.102.048264
You have access
Glycoprotein IIb/IIIa Receptor Antagonist (2S)-2-[(2-Naphthyl-sulfonyl)amino]-3-{[2-({4-(4-piperidinyl)-2-[2-(4-piperidinyl)ethyl] butanoyl}amino)acetyl]amino}propanoic Acid Dihydrochloride (CRL42796), in Combination with Aspirin and/or Enoxaparin, Prevents Coronary Artery Rethrombosis after Successful Thrombolytic Treatment by Recombinant Tissue Plasminogen Activator
Ting-Ting Hong, Edward M. Driscoll, Andrew J. White, Ardaman Sherigill, Thierry A. Giboulot and Benedict R. Lucchesi

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 616-623; DOI: https://doi.org/10.1124/jpet.103.052886
You have access
A Growth Hormone Secretagogue Prevents Ischemic-Induced Mortality Independently of the Growth Hormone Pathway in Dogs with Chronic Dilated Cardiomyopathy
You-Tang Shen, Joseph J. Lynch, Richard J. Hargreaves and Robert J. Gould

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 815-820; DOI: https://doi.org/10.1124/jpet.103.050997

CELLULAR AND MOLECULAR

You have access
Morphine and Endomorphins Differentially Regulate μ-Opioid Receptor mRNA in SHSY-5Y Human Neuroblastoma Cells
Xin Yu, Xin Mao, Allan D. Blake, Wen Xin Li and Sulie L. Chang

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 447-454; DOI: https://doi.org/10.1124/jpet.103.048694
You have access
Expression and Molecular Pharmacology of the Mouse CRTH2 Receptor
Aaron N. Hata, Roy Zent, Matthew D. Breyer and Richard M. Breyer

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 463-470; DOI: https://doi.org/10.1124/jpet.103.050955
You have access
Mutational Uncoupling of α_1A-Adrenergic Receptors from G Proteins Also Uncouples Mitogenic and Transcriptional Responses in PC12 Cells
Deborah Lee, Anna Robeva, Zhongjian Chen and Kenneth P. Minneman

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 471-477; DOI: https://doi.org/10.1124/jpet.103.050500
You have access
Identification of Residues That Confer α-Conotoxin-PnIA Sensitivity on the α3 Subunit of Neuronal Nicotinic Acetylcholine Receptors
Drew Everhart, Edward Reiller, Armen Mirzoian, J. Michael McIntosh, Arun Malhotra and Charles W. Luetje

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 664-670; DOI: https://doi.org/10.1124/jpet.103.051656
You have access
Neocarzinostatin Induces an Effective p53-Dependent Response in Human Papillomavirus-Positive Cervical Cancer Cells
Adriana Bañuelos, Elba Reyes, Rodolfo Ocadiz, Elizabeth Alvarez, Martha Moreno, Alberto Monroy and Patricio Gariglio

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 671-680; DOI: https://doi.org/10.1124/jpet.103.051557
You have access
Involvement of Endocytic Organelles in the Subcellular Trafficking and Localization of Riboflavin
Se-Ne Huang, Mitch A. Phelps and Peter W. Swaan

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 681-687; DOI: https://doi.org/10.1124/jpet.103.051581
You have access
PAT5A: A Partial Agonist of Peroxisome Proliferator-Activated Receptor γ Is a Potent Antidiabetic Thiazolidinedione Yet Weakly Adipogenic
Parimal Misra, Ranjan Chakrabarti, Reeba K. Vikramadithyan, Gopalakrishnan Bolusu, Suresh Juluri, Jagadheshan Hiriyan, Cynthia Gershome, Abdul Rajjak, Papreddy Kashireddy, Songtao Yu, Sailesh Surapureddi, Chao Qi, Yi-Jun Zhu, M. Sambasiva Rao, Janardan K. Reddy and Rajagopalan Ramanujam

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 763-771; DOI: https://doi.org/10.1124/jpet.103.049791

ENDOCRINE AND REPRODUCTIVE

You have access
The Role of I₁-Imidazoline and α₂-Adrenergic Receptors in the Modulation of Glucose Metabolism in the Spontaneously Hypertensive Obese Rat Model of Metabolic Syndrome X
Rodney A. Velliquette and Paul Ernsberger

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 646-657; DOI: https://doi.org/10.1124/jpet.103.050468
You have access
Functional Melatonin Receptors in Rat Ovaries at Various Stages of the Estrous Cycle
Jose M. Soares, Monica I. Masana, Çağatay Erşahin and Margarita L. Dubocovich

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 694-702; DOI: https://doi.org/10.1124/jpet.103.049916

GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL

You have access
Renal Action of Acute Chloroquine and Paracetamol Administration in the Anesthetized, Fluid-Balanced Rat
Mohamed H. Ahmed, Richard J. Balment and Nick Ashton

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 478-483; DOI: https://doi.org/10.1124/jpet.103.051037
You have access
Stimulatory Action of Itopride Hydrochloride on Colonic Motor Activity in Vitro and in Vivo
Tadashi Tsubouchi, Takaharu Saito, Fujie Mizutani, Toshie Yamauchi and Yuji Iwanaga

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 787-793; DOI: https://doi.org/10.1124/jpet.102.048603

INFLAMMATION AND IMMUNOPHARMACOLOGY

You have access
The Expression of δ- and κ-Opioid Receptor Is Enhanced during Intestinal Inflammation in Mice
Olga Pol, José R. Palacio and Margarita M. Puig

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 455-462; DOI: https://doi.org/10.1124/jpet.103.049346
You have access
Dissection of the Anti-Inflammatory Effect of the Core and C-Terminal (KPV) α-Melanocyte-Stimulating Hormone Peptides
Stephen J. Getting, Helgi B. Schiöth and Mauro Perretti

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 631-637; DOI: https://doi.org/10.1124/jpet.103.051623
You have access
A Lymphocyte-Generated Fragment of Vasoactive Intestinal Peptide with VPAC1 Agonist Activity and VPAC2 Antagonist Effects
Monica A. Summers, M. Sue O'Dorisio, Mary O. Cox, Maria Lara-Marquez and Edward J. Goetzl

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 638-645; DOI: https://doi.org/10.1124/jpet.103.050583

NEUROPHARMACOLOGY

You have access
Characterization of the Binding of [³H][Dmt¹]H-Dmt-d-Arg-Phe-Lys-NH₂, a Highly Potent Opioid Peptide
Claire L. Neilan, Adam J. Janvey, Elizabeth Bolan, Irena Berezowska, Thi M.-D. Nguyen, Peter W. Schiller and Gavril W. Pasternak

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 430-436; DOI: https://doi.org/10.1124/jpet.103.049742
You have access
Ethanol Excitation of Dopaminergic Ventral Tegmental Area Neurons Is Blocked by Quinidine
Sarah B. Appel, Zhaoping Liu, Maureen A. McElvain and Mark S. Brodie

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 437-446; DOI: https://doi.org/10.1124/jpet.103.050963
You have access
Role of Nitric-Oxide Synthase Isoforms in Nitrous Oxide Antinociception in Mice
Masago Ishikawa and Raymond M. Quock

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 484-489; DOI: https://doi.org/10.1124/jpet.103.049551
You have access
Vinpocetine Is a Potent Blocker of Rat Na_V1.8 Tetrodotoxin-Resistant Sodium Channels
Xiaoping Zhou, Xiao-Wei Dong, James Crona, Maureen Maguire and Tony Priestley

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 498-504; DOI: https://doi.org/10.1124/jpet.103.051086
You have access
Ethanol Inhibits α-Amino-3-hydyroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Function in Central Nervous System Neurons by Stabilizing Desensitization
Tommi Möykkynen, Esa R. Korpi and David M. Lovinger

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 546-555; DOI: https://doi.org/10.1124/jpet.103.050666
You have access
Chronic Fluoxetine Differentially Affects 5-Hydroxytryptamine_2A Receptor Signaling in Frontal Cortex, Oxytocin- and Corticotropin-Releasing Factor-Containing Neurons in Rat Paraventricular Nucleus
K. J. Damjanoska, L. D. Van de Kar, G. H. Kindel, Y. Zhang, D. N. D'Souza, F. Garcia, G. Battaglia and N. A. Muma

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 563-571; DOI: https://doi.org/10.1124/jpet.103.050534
You have access
Suppressed Prolactin Response to Dynorphin A_1–13 in Methadone-Maintained Versus Control Subjects
Gavin Bart, Lisa Borg, James H. Schluger, Mark Green, Ann Ho and Mary Jeanne Kreek

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 581-587; DOI: https://doi.org/10.1124/jpet.103.050682
You have access
Neuroprotective Effects of (S)-N-[4-[4-[(3,4-Dihydro-6-hydroxy-2,5,7,8 -tetramethyl-2H-1-benzopyran-2-yl)carbonyl]-1-piperazinyl]phenyl]-2 -thiophenecarboximid-amide (BN 80933), an Inhibitor of Neuronal Nitric-Oxide Synthase and an Antioxidant, in Model of Transient Focal Cerebral Ischemia in Mice
Li Ding-Zhou, Catherine Marchand-Verrecchia, Bruno Palmier, Nicole Croci, Pierre-Etienne Chabrier, Michel Plotkine and Isabelle Margaill

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 588-594; DOI: https://doi.org/10.1124/jpet.103.051490
You have access
A Mutation in Transmembrane Domain II of the 5-Hydroxytryptamine_3A Receptor Stabilizes Channel Opening and Alters Alcohol Modulatory Actions
J. S. Sessoms-Sikes, Margaret E. Hamilton, Li-Xin Liu, David M. Lovinger and Tina K. Machu

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 595-604; DOI: https://doi.org/10.1124/jpet.103.050542
You have access
Regulation of Septo-Hippocampal Activity by 5-Hydroxytryptamine_2C Receptors
Mihály Hajós, William E. Hoffmann and Royal J. Weaver

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 605-615; DOI: https://doi.org/10.1124/jpet.103.051169
You have access
Nifedipine-Mediated Mobilization of Intracellular Calcium Stores Increases Spontaneous Neurotransmitter Release at Neonatal Rat Motor Nerve Terminals
J. Piriz, M. D. Rosato Siri, R. Pagani and O. D. Uchitel

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 658-663; DOI: https://doi.org/10.1124/jpet.103.051524
You have access
Increased Expression of Vanilloid Receptor 1 on Myelinated Primary Afferent Neurons Contributes to the Antihyperalgesic Effect of Capsaicin Cream in Diabetic Neuropathic Pain in Mice
Md Harunor Rashid, Makoto Inoue, Shiho Bakoshi and Hiroshi Ueda

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 709-717; DOI: https://doi.org/10.1124/jpet.103.050948
You have access
σ-1 Receptors (σ₁ Binding Sites) Form Raft-Like Microdomains and Target Lipid Droplets on the Endoplasmic Reticulum: Roles in Endoplasmic Reticulum Lipid Compartmentalization and Export
Teruo Hayashi and Tsung-Ping Su

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 718-725; DOI: https://doi.org/10.1124/jpet.103.051284
You have access
Intracellular Dynamics of σ-1 Receptors (σ₁ Binding Sites) in NG108-15 Cells
Teruo Hayashi and Tsung-Ping Su

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 726-733; DOI: https://doi.org/10.1124/jpet.103.051292
You have access
Hyperlocomotive and Discriminative Stimulus Effects of Cocaine Are Under the Control of Serotonin_2C (5-HT_2C) Receptors in Rat Prefrontal Cortex
Malgorzata Filip and Kathryn A. Cunningham

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 734-743; DOI: https://doi.org/10.1124/jpet.102.045716
You have access
LY503430, a Novel α-Amino-3-hydroxy-5-methylisoxazole-4-propionic Acid Receptor Potentiator with Functional, Neuroprotective and Neurotrophic Effects in Rodent Models of Parkinson's Disease
Tracey K. Murray, Katherine Whalley, Christine S. Robinson, Mark A. Ward, Caroline A. Hicks, David Lodge, Jim L. Vandergriff, Polly Baumbarger, Edward Siuda, Mary Gates, Ann M. Ogden, Phil Skolnick, Dennis M. Zimmerman, Eric S. Nisenbaum, David Bleakman and Michael J. O'Neill

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 752-762; DOI: https://doi.org/10.1124/jpet.103.049445
You have access
Nicotinic Acetylcholine Receptor-Mediated Neuroprotection by Donepezil Against Glutamate Neurotoxicity in Rat Cortical Neurons
Yuki Takada, Atsushi Yonezawa, Toshiaki Kume, Hiroshi Katsuki, Shuji Kaneko, Hachiro Sugimoto and Akinori Akaike

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 772-777; DOI: https://doi.org/10.1124/jpet.103.050104
You have access
Mediation of Corticotropin Releasing Factor Type 1 Receptor Phosphorylation and Desensitization by Protein Kinase C: A Possible Role in Stress Adaptation
Richard L. Hauger, J. Alberto Olivares-Reyes, Sandra Braun, Kevin J. Catt and Frank M. Dautzenberg

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 794-803; DOI: https://doi.org/10.1124/jpet.103.050088
You have access
Antinociceptive Activity of the N-Methyl-d-aspartate Receptor Antagonist N-(2-Indanyl)-glycinamide Hydrochloride (CHF3381) in Experimental Models of Inflammatory and Neuropathic Pain
Gino Villetti, Marco Bergamaschi, Franco Bassani, Pier Tonino Bolzoni, Marisa Maiorino, Claudio Pietra, Ivano Rondelli, Philippe Chamiot-Clerc, Michele Simonato and Mario Barbieri

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 804-814; DOI: https://doi.org/10.1124/jpet.103.050039

TOXICOLOGY

You have access
Oxidative Stress-Induced Homologous Recombination As a Novel Mechanism for Phenytoin-Initiated Toxicity
Louise M. Winn, Perry M. Kim and Jac A. Nickoloff

Journal of Pharmacology and Experimental Therapeutics August 2003, 306 (2) 523-527; DOI: https://doi.org/10.1124/jpet.103.052639

Main menu

User menu

Search

Table of Contents

PERSPECTIVES IN PHARMACOLOGY

ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

BEHAVIORAL PHARMACOLOGY

CARDIOVASCULAR

CELLULAR AND MOLECULAR

ENDOCRINE AND REPRODUCTIVE

GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL

INFLAMMATION AND IMMUNOPHARMACOLOGY

NEUROPHARMACOLOGY

TOXICOLOGY

In this issue

Jump to

Navigate

More Information

ASPET's Other Journals