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Research ArticleABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

The Cytochrome P450 2B6 (CYP2B6) Is the Main Catalyst of Efavirenz Primary and Secondary Metabolism: Implication for HIV/AIDS Therapy and Utility of Efavirenz as a Substrate Marker of CYP2B6 Catalytic Activity

Bryan A. Ward, J. Christopher Gorski, David R. Jones, Stephen D. Hall, David A. Flockhart and Zeruesenay Desta
Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 287-300; DOI: https://doi.org/10.1124/jpet.103.049601
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Research ArticleABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

The Cytochrome P450 2B6 (CYP2B6) Is the Main Catalyst of Efavirenz Primary and Secondary Metabolism: Implication for HIV/AIDS Therapy and Utility of Efavirenz as a Substrate Marker of CYP2B6 Catalytic Activity

Bryan A. Ward, J. Christopher Gorski, David R. Jones, Stephen D. Hall, David A. Flockhart and Zeruesenay Desta
Journal of Pharmacology and Experimental Therapeutics July 1, 2003, 306 (1) 287-300; DOI: https://doi.org/10.1124/jpet.103.049601
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