Journal of Pharmacology and Experimental Therapeutics: 306 (1)

July 01, 2003; Volume 306,Issue 1

PERSPECTIVES IN PHARMACOLOGY

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Ontogenesis of β-Adrenoceptor Signaling: Implications for Perinatal Physiology and for Fetal Effects of Tocolytic Drugs
Theodore A. Slotkin, J. Todd Auman and Frederic J. Seidler

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 1-7; DOI: https://doi.org/10.1124/jpet.102.048421

ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

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Contribution of Organic Anion Transporter 3 (Slc22a8) to the Elimination of p-Aminohippuric Acid and Benzylpenicillin across the Blood-Brain Barrier
Ryota Kikuchi, Hiroyuki Kusuhara, Daisuke Sugiyama and Yuichi Sugiyama

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 51-58; DOI: https://doi.org/10.1124/jpet.103.049197
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Transfer of l-α-Acetylmethadol (LAAM) and l-α-Acetyl-N-normethadol (norLAAM) by the Perfused Human Placental Lobule
Tatiana N. Nanovskaya, Sujal V. Deshmukh, Rachel Miles, Steve Burmaster and Mahmoud S. Ahmed

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 205-212; DOI: https://doi.org/10.1124/jpet.103.050690
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The Cytochrome P450 2B6 (CYP2B6) Is the Main Catalyst of Efavirenz Primary and Secondary Metabolism: Implication for HIV/AIDS Therapy and Utility of Efavirenz as a Substrate Marker of CYP2B6 Catalytic Activity
Bryan A. Ward, J. Christopher Gorski, David R. Jones, Stephen D. Hall, David A. Flockhart and Zeruesenay Desta

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 287-300; DOI: https://doi.org/10.1124/jpet.103.049601
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The Site-Specific Transport and Metabolism of Tacrolimus in Rat Small Intestine
Shigeki Tamura, Yuji Tokunaga, Rinta Ibuki, Gordon L. Amidon, Hitoshi Sezaki and Shinji Yamashita

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 310-316; DOI: https://doi.org/10.1124/jpet.103.050716
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Pharmacokinetic and Pharmacodynamic Modeling of Recombinant Human Erythropoietin after Intravenous and Subcutaneous Dose Administration in Cynomolgus Monkeys
Rohini Ramakrishnan, Wing K. Cheung, Francis Farrell, Linda Joffee and William J. Jusko

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 324-331; DOI: https://doi.org/10.1124/jpet.102.047191
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Effect of Atorvastatin on Apolipoprotein B100 Containing Lipoprotein Metabolism in Type-2 Diabetes
Khadija Ouguerram, Thierry Magot, Yassine Zäir, J. S. Marchini, Bernard Charbonnel, Herve Laouenan and Michel Krempf

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 332-337; DOI: https://doi.org/10.1124/jpet.103.048991

BEHAVIORAL PHARMACOLOGY

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The Cannabinoid CB1 Antagonist N-Piperidinyl-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl) -4-methylpyrazole-3-carboxamide (SR-141716A) Differentially Alters the Reinforcing Effects of Heroin under Continuous Reinforcement, Fixed Ratio, and Progressive Ratio Schedules of Drug Self-Administration in Rats
M. Solinas, L. V. Panlilio, K. Antoniou, L. A. Pappas and S. R. Goldberg

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 93-102; DOI: https://doi.org/10.1124/jpet.102.047928
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Metabotropic Glutamate Subtype 5 Receptors Modulate Locomotor Activity and Sensorimotor Gating in Rodents
Gene G. Kinney, Maryann Burno, Una C. Campbell, Lisa M. Hernandez, Dana Rodriguez, Linda J. Bristow and P. Jeffrey Conn

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 116-123; DOI: https://doi.org/10.1124/jpet.103.048702
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Risperidone Attenuates the Discriminative-Stimulus Effects of d-Amphetamine in Humans
Craig R. Rush, William W. Stoops, Lon R. Hays, Paul E. A. Glaser and Lon S. Hays

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 195-204; DOI: https://doi.org/10.1124/jpet.102.048439
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5-Hydroxytryptamine (5-HT)₂ Receptor Involvement in Acute 5-HT-Evoked Scratching but Not in Allergic Pruritus Induced by Dinitrofluorobenzene in Rats
Hiroshi Nojima and E. Carstens

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 245-252; DOI: https://doi.org/10.1124/jpet.103.049239
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The Subtype-Selective Nicotinic Acetylcholine Receptor Agonist SIB-1553A Improves Both Attention and Memory Components of a Spatial Working Memory Task in Chronic Low Dose 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Treated Monkeys
J. S. Schneider, J. P. Tinker, F. Menzaghi and G. K. Lloyd

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 401-406; DOI: https://doi.org/10.1124/jpet.103.051912

CARDIOVASCULAR

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Enhancement of Angiogenesis by Endogenous Substance P Release and Neurokinin-1 Receptors During Neurogenic Inflammation
Hélène C. Seegers, Vivienne C. Hood, Bruce L. Kidd, Simon C. Cruwys and David A. Walsh

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 8-12; DOI: https://doi.org/10.1124/jpet.103.050013
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Nitric Oxide Inhibitor N^ω-Nitro-l-arginine Methyl Ester Potentiates Induction of Heme Oxygenase-1 in Kidney Ischemia/Reperfusion Model: A Novel Mechanism for Regulation of the Oxygenase
Robert D. Mayer, Xiaojun Wang and Mahin D. Maines

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 43-50; DOI: https://doi.org/10.1124/jpet.102.048686
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BM-573, a Dual Thromboxane Synthase Inhibitor and Thromboxane Receptor Antagonist, Prevents Pig Myocardial Infarction Induced by Coronary Thrombosis
S. Rolin, M. Petein, V. Tchana-Sato, J. M. Dogne, P. Benoit, B. Lambermont, A. Ghuysen, P. Kolh and B. Masereel

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 59-65; DOI: https://doi.org/10.1124/jpet.102.046607
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Protective Effect of Chronic Vitamin C Treatment on Endothelial Function of Apolipoprotein E-Deficient Mouse Carotid Artery
Takuya Matsumoto, Livius V. d'uscio, Daihiko Eguchi, Masahiko Akiyama, Leslie A. Smith and Zvonimir S. Katusic

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 103-108; DOI: https://doi.org/10.1124/jpet.103.049163
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Increased Endothelin-Induced Ca²⁺ Signaling, Tyrosine Phosphorylation, and Coronary Artery Disease in Diabetic Dyslipidemic Swine Are Prevented by Atorvastatin
D. L. Lee, B. R. Wamhoff, L. C. Katwa, H. K. Reddy, D. J. Voelker, J. L. Dixon and M. Sturek

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 132-140; DOI: https://doi.org/10.1124/jpet.103.049577
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Differential Effects of Phosphodiesterase-Sensitive and -Resistant Analogs of cAMP on Initiation of Contraction in Cardiac Ventricular Myocytes
Gregory R. Ferrier and Susan E. Howlett

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 166-178; DOI: https://doi.org/10.1124/jpet.103.049676
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Ectonucleotidase in Sympathetic Nerve Endings Modulates ATP and Norepinephrine Exocytosis in Myocardial Ischemia
Casilde Sesti, Motohiro Koyama, M. Johan Broekman, Aaron J. Marcus and Roberto Levi

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 238-244; DOI: https://doi.org/10.1124/jpet.103.049874
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Effects of Chronic Ethanol Feeding on Clonidine-Evoked Reductions in Blood Pressure, Heart Rate, and Their Variability: Time-Domain Analyses
Mahmoud M. El-Mas and Abdel A. Abdel-Rahman

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 271-278; DOI: https://doi.org/10.1124/jpet.102.048355

CELLULAR AND MOLECULAR

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Evidence That Nuclear Factor-κB Activation Is Critical in Oxidant-Induced Disruption of the Microtubule Cytoskeleton and Barrier Integrity and That Its Inactivation Is Essential in Epidermal Growth Factor-Mediated Protection of the Monolayers of Intestinal Epithelia
A. Banan, A. Farhadi, J. Z. Fields, E. Mutlu, L. Zhang and A. Keshavarzian

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 13-28; DOI: https://doi.org/10.1124/jpet.102.047415
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Green Tea Polyphenols Induce Differentiation and Proliferation in Epidermal Keratinocytes
Stephen Hsu, Wendy B. Bollag, Jill Lewis, Qin Huang, Baldev Singh, Mohamed Sharawy, Tetsuya Yamamoto and George Schuster

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 29-34; DOI: https://doi.org/10.1124/jpet.103.049734
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Amide Local Anesthetics Potently Inhibit the Human Tandem Pore Domain Background K⁺ Channel TASK-2 (KCNK5)
Christoph H. Kindler, Matthias Paul, Hilary Zou, Canhui Liu, Bruce D. Winegar, Andrew T. Gray and C. Spencer Yost

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 84-92; DOI: https://doi.org/10.1124/jpet.103.049809
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The Use of Bioluminescence Resonance Energy Transfer 2 to Study Neuropeptide Y Receptor Agonist-Induced β-Arrestin 2 Interaction
Magnus M. Berglund, Douglas A. Schober, Michael A. Statnick, Patricia H. McDonald and Donald R. Gehlert

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 147-156; DOI: https://doi.org/10.1124/jpet.103.051227

ENDOCRINE AND REPRODUCTIVE

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Pharmacology of (2S,4Z)-N-[(2S)-2-Hydroxy-2-phenylethyl]-4-(methoxyimino) -1-[(2′-methyl[1,1′-biphenyl]-4-yl)carbonyl]-2-pyrrolidinecarboxamide, a New Potent and Selective Nonpeptide Antagonist of the Oxytocin Receptor
Rocco Cirillo, Enrico Gillio Tos, Matthias K. Schwarz, Anna Quattropani, Alexander Scheer, Marc Missotten, Jerôme Dorbais, Anthony Nichols, Francesco Borrelli, Claudio Giachetti, Lucia Golzio, Paolo Marinelli, Russell J. Thomas, Claude Chevillard, Florence Laurent, Karine Portet, Claude Barberis and André Chollet

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 253-261; DOI: https://doi.org/10.1124/jpet.103.049395

GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL

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Toxicity of Acetaminophen, Salicylic Acid, and Caffeine for First-Passage Rat Renal Inner Medullary Collecting Duct Cells
Qi Cai, Natalia I. Dmitrieva, Luis F. Michea, Gerson Rocha, Douglas Ferguson and Maurice B. Burg

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 35-42; DOI: https://doi.org/10.1124/jpet.102.047431
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Ursodeoxycholate Reduces Ethinylestradiol Glucuronidation in the Rat: Role in Prevention of Estrogen-Induced Cholestasis
Enrique J. Sánchez Pozzi, Fernando A. Crocenzi, José M. Pellegrino, Viviana A. Catania, Marcelo G. Luquita, Marcelo G. Roma, Emilio A. Rodríguez Garay and Aldo D. Mottino

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 279-286; DOI: https://doi.org/10.1124/jpet.103.049940
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Glucagon-Like Peptide-2 and Common Therapeutics in a Murine Model of Ulcerative Colitis
Marie-Claude L'Heureux and Patricia L. Brubaker

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 347-354; DOI: https://doi.org/10.1124/jpet.103.051771
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Uptake of Serotonin at the Apical and Basolateral Membranes of Human Intestinal Epithelial (Caco-2) Cells Occurs through the Neuronal Serotonin Transporter (SERT)
Fátima Martel, Rosário Monteiro and Clara Lemos

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 355-362; DOI: https://doi.org/10.1124/jpet.103.049668

INFLAMMATION AND IMMUNOPHARMACOLOGY

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Receptor-Mediated Pharmacokinetics and Pharmacodynamics of Interferon-β1a in Monkeys
Donald E. Mager, Berend Neuteboom, Constantinos Efthymiopoulos, Alain Munafo and William J. Jusko

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 262-270; DOI: https://doi.org/10.1124/jpet.103.049502

NEUROPHARMACOLOGY

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Functional Characterization of YM928, a Novel Noncompetitive α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Antagonist
Kazushige Ohno, Rie Tsutsumi, Naoyuki Matsumoto, Hiroshi Yamashita, Yoko Amada, Jun-Ichi Shishikura, Hiroshi Inami Shin-Ichi Yatsugi, Masamichi Okada, Shuichi Sakamoto and Tokio Yamaguchi

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 66-72; DOI: https://doi.org/10.1124/jpet.103.049973
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Human Pharmacology of Ayahuasca: Subjective and Cardiovascular Effects, Monoamine Metabolite Excretion, and Pharmacokinetics
Jordi Riba, Marta Valle, Gloria Urbano, Mercedes Yritia, Adelaida Morte and Manel J. Barbanoj

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 73-83; DOI: https://doi.org/10.1124/jpet.103.049882
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Converging Protein Kinase Pathways Mediate Adenylyl Cyclase Superactivation upon Chronic δ-Opioid Agonist Treatment
Eva V. Varga, Marc K. Rubenzik, Dagmar Stropova, Masano Sugiyama, Vanessa Grife, Victor J. Hruby, Kenner C. Rice, William R. Roeske and Henry I. Yamamura

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 109-115; DOI: https://doi.org/10.1124/jpet.103.049643
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Multidrug Resistance Protein MRP2 Contributes to Blood-Brain Barrier Function and Restricts Antiepileptic Drug Activity
Heidrun Potschka, Maren Fedrowitz and Wolfgang Löscher

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 124-131; DOI: https://doi.org/10.1124/jpet.103.049858
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Nocistatin and Prepro-Nociceptin/Orphanin FQ 160–187 Cause Nociception through Activation of G_i/o in Capsaicin-Sensitive and of G_s in Capsaicin-Insensitive Nociceptors, Respectively
Makoto Inoue, Toshiko Kawashima, Richard G. Allen and Hiroshi Ueda

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 141-146; DOI: https://doi.org/10.1124/jpet.103.049361
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Studies of μ-, κ-, and δ-Opioid Receptor Density and G Protein Activation in the Cortex and Thalamus of Monkeys
M. C. H. Ko, H. Lee, C. Harrison, M. J. Clark, H. F. Song, N. N. Naughton, J. H. Woods and J. R. Traynor

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 179-186; DOI: https://doi.org/10.1124/jpet.103.050625
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Effect of N-(4-Acetyl-1-piperazinyl)-p-fluorobenzamide Monohydrate (FK960), an Antidementia Drug with a Novel Mechanism of Action, on Regional Cerebral Blood Flow and Glucose Metabolism in Aged Rhesus Macaques Studied with Positron Emission Tomography
Akihiro Noda, Hiroyuki Takamatsu, Nobuya Matsuoka, Satoshi Koyama, Hideo Tsukada and Shintaro Nishimura

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 213-217; DOI: https://doi.org/10.1124/jpet.103.050245
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Inhibitors of Cyclooxygenase-2, but Not Cyclooxygenase-1 Provide Structural and Functional Protection against Quinolinic Acid-Induced Neurodegeneration
Heather C. Salzberg-Brenhouse, Er-Yun Chen, Dwaine F. Emerich, Sam Baldwin, Ken Hogeland, Sharon Ranelli, Denise Lafreniere, Brigido Perdomo, Leah Novak, Theodora Kladis, Karen Fu, Anthony S. Basile, Jeffrey H. Kordower and Raymond T. Bartus

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 218-228; DOI: https://doi.org/10.1124/jpet.103.049700
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Evaluation of the Ocular Hypotensive Response of Serotonin 5-HT_1A and 5-HT₂ Receptor Ligands in Conscious Ocular Hypertensive Cynomolgus Monkeys
Jesse A. May, Marsha A. McLaughlin, Najam A. Sharif, Mark R. Hellberg and Thomas R. Dean

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 301-309; DOI: https://doi.org/10.1124/jpet.103.049528
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Distinct Recognition of Substrates by the Human and Drosophila Serotonin Transporters
G. J. Rodríguez, D. L. Roman, K. J. White, D. E. Nichols and E. L. Barker

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 338-346; DOI: https://doi.org/10.1124/jpet.103.048751
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Synthesis and Characterization of NESS 0327: A Novel Putative Antagonist of the CB₁ Cannabinoid Receptor
Stefania Ruiu, Gèrard A. Pinna, Giorgio Marchese, Jean-Mario Mussinu, Pierluigi Saba, Simone Tambaro, Paola Casti, Romina Vargiu and Luca Pani

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 363-370; DOI: https://doi.org/10.1124/jpet.103.049924
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Improved Brain Uptake and Pharmacological Activity of Dalargin Using a Peptide-Vector-Mediated Strategy
Christophe Rousselle, Philippe Clair, Maria Smirnova, Yuri Kolesnikov, Gavril W. Pasternak, Stéphanie Gac-Breton, Anthony R. Rees, Jean-Michel Scherrmann and Jamal Temsamani

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 371-376; DOI: https://doi.org/10.1124/jpet.102.048520
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N-(4-Tertiarybutylphenyl)-4-(3-chloropyridin-2-yl)tetrahydropyrazine -1(2H)-carbox-amide (BCTC), a Novel, Orally Effective Vanilloid Receptor 1 Antagonist with Analgesic Properties: I. In Vitro Characterization and Pharmacokinetic Properties
Kenneth J. Valenzano, Elfrida R. Grant, Gang Wu, Mohamed Hachicha, Lori Schmid, Laykea Tafesse, Qun Sun, Yakov Rotshteyn, Joseph Francis, James Limberis, Shiazah Malik, Edward R. Whittemore and Dianne Hodges

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 377-386; DOI: https://doi.org/10.1124/jpet.102.045674
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N-(4-Tertiarybutylphenyl)-4-(3-cholorphyridin-2-yl)tetrahydropyrazine -1(2H)-carbox-amide (BCTC), a Novel, Orally Effective Vanilloid Receptor 1 Antagonist with Analgesic Properties: II. In Vivo Characterization in Rat Models of Inflammatory and Neuropathic Pain
James D. Pomonis, James E. Harrison, Lilly Mark, David R. Bristol, Kenneth J. Valenzano and Katharine Walker

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 387-393; DOI: https://doi.org/10.1124/jpet.102.046268
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Buprenorphine Blocks ϵ- and μ-Opioid Receptor-Mediated Antinociception in the Mouse
Hirokazu Mizoguchi, Amanda Spaulding, Randy Leitermann, Hsiang-En Wu, Hiroshi Nagase and Leon F. Tseng

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 394-400; DOI: https://doi.org/10.1124/jpet.103.048835
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SSR591813, a Novel Selective and Partial α₄β₂ Nicotinic Receptor Agonist with Potential as an Aid to Smoking Cessation
C. Cohen, O. E. Bergis, F. Galli, A. W. Lochead, S. Jegham, B. Biton, J. Léonardon, P. Avenet, F. Sgard, F. Besnard, D. Graham, A. Coste, A. Oblin, O. Curet, C. Voltz, A. Gardes, D. Caille, G. Perrault, P. George, P. Soubrié and B. Scatton

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 407-420; DOI: https://doi.org/10.1124/jpet.103.049262

TOXICOLOGY

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Protein Kinase C Mediates Repair of Mitochondrial and Transport Functions after Toxicant-Induced Injury in Renal Cells
Grażyna Nowak

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 157-165; DOI: https://doi.org/10.1124/jpet.103.050336
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In Vivo Effect of PC-SPES on Prostate Growth and Hepatic CYP3A Expression in Rats
Teri Wadsworth, Hataya Poonyagariyagorn, Elinore Sullivan, Dennis Koop and Charles E. Roselli

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 187-194; DOI: https://doi.org/10.1124/jpet.102.048645
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Characterization of Sulfamethoxazole and Sulfamethoxazole Metabolite-Specific T-Cell Responses in Animals and Humans
John Farrell, Dean J. Naisbitt, Nicola S. Drummond, Jan P. H. Depta, F. Javier Vilar, Munir Pirmohamed and B. Kevin Park

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 229-237; DOI: https://doi.org/10.1124/jpet.103.050112
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In Vitro Cytotoxicity of 4-Methylcatechol in Murine Tumor Cells: Induction of Apoptotic Cell Death by Extracellular Pro-Oxidant Action
Kyoji Morita, Hideki Arimochi and Yoshinari Ohnishi

Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 317-323; DOI: https://doi.org/10.1124/jpet.103.050351

Erratum

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Correction to “Nitric Oxide-Donating Nonsteroidal Anti-Inflammatory Drugs Inhibit the Growth of Various Cultured Human Cancer Cells: Evidence of a Tissue Type-Independent Effect”
Journal of Pharmacology and Experimental Therapeutics July 2003, 306 (1) 421;

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Table of Contents

PERSPECTIVES IN PHARMACOLOGY

ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

BEHAVIORAL PHARMACOLOGY

CARDIOVASCULAR

CELLULAR AND MOLECULAR

ENDOCRINE AND REPRODUCTIVE

GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL

INFLAMMATION AND IMMUNOPHARMACOLOGY

NEUROPHARMACOLOGY

TOXICOLOGY

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