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Research ArticlePERSPECTIVES IN PHARMACOLOGY

Genetics and Susceptibility to Toxic Chemicals: Do You (or Should You) Know Your Genetic Profile?

Lawrence H. Lash, Ronald N. Hines, Frank J. Gonzalez, Timothy R. Zacharewski and Mark A. Rothstein
Journal of Pharmacology and Experimental Therapeutics May 2003, 305 (2) 403-409; DOI: https://doi.org/10.1124/jpet.102.039925
Lawrence H. Lash
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Ronald N. Hines
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Frank J. Gonzalez
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Timothy R. Zacharewski
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Mark A. Rothstein
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Journal of Pharmacology and Experimental Therapeutics: 305 (2)
Journal of Pharmacology and Experimental Therapeutics
Vol. 305, Issue 2
1 May 2003
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Research ArticlePERSPECTIVES IN PHARMACOLOGY

Genetics and Susceptibility to Toxic Chemicals: Do You (or Should You) Know Your Genetic Profile?

Lawrence H. Lash, Ronald N. Hines, Frank J. Gonzalez, Timothy R. Zacharewski and Mark A. Rothstein
Journal of Pharmacology and Experimental Therapeutics May 1, 2003, 305 (2) 403-409; DOI: https://doi.org/10.1124/jpet.102.039925

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Research ArticlePERSPECTIVES IN PHARMACOLOGY

Genetics and Susceptibility to Toxic Chemicals: Do You (or Should You) Know Your Genetic Profile?

Lawrence H. Lash, Ronald N. Hines, Frank J. Gonzalez, Timothy R. Zacharewski and Mark A. Rothstein
Journal of Pharmacology and Experimental Therapeutics May 1, 2003, 305 (2) 403-409; DOI: https://doi.org/10.1124/jpet.102.039925
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  • Article
    • Abstract
    • Pharmacogenetics and Susceptibility to Toxic Chemicals: Historical Perspective, Current Status and Future Challenges
    • Use of Gene Knockout and Transgenic Mice to Study the Roles of Xenobiotic-Metabolizing Enzymes in Toxicology
    • Gene Expression Profiling in Mechanistic and Predictive Toxicology
    • Ethical and Legal Implications of Pharmacogenetics
    • Conclusions
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