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Research ArticleABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

In Vivo Modulation of Intestinal CYP3A Metabolism by P-Glycoprotein: Studies Using the Rat Single-Pass Intestinal Perfusion Model

Carolyn L. Cummins, Laurent Salphati, Michael J. Reid and Leslie Z. Benet
Journal of Pharmacology and Experimental Therapeutics April 2003, 305 (1) 306-314; DOI: https://doi.org/10.1124/jpet.102.044719

Article Information

vol. 305 no. 1 306-314
DOI 
https://doi.org/10.1124/jpet.102.044719
PubMed 
12649383
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received September 23, 2002
  • Accepted December 30, 2002
  • Published online April 1, 2003.

Article Versions

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Carolyn L. Cummins,
  2. Laurent Salphati,
  3. Michael J. Reid and
  4. Leslie Z. Benet
  1. Department of Biopharmaceutical Sciences, University of California, San Francisco, California
  1. Prof. Leslie Z. Benet, Biopharmaceutical Sciences, 533 Parnassus Ave. U-68, University of California, San Francisco, CA, 94143-0446. E-mail:benet{at}itsa.ucsf.edu
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Research ArticleABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

In Vivo Modulation of Intestinal CYP3A Metabolism by P-Glycoprotein: Studies Using the Rat Single-Pass Intestinal Perfusion Model

Carolyn L. Cummins, Laurent Salphati, Michael J. Reid and Leslie Z. Benet
Journal of Pharmacology and Experimental Therapeutics April 1, 2003, 305 (1) 306-314; DOI: https://doi.org/10.1124/jpet.102.044719
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