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Research ArticleABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

Human Organic Anion Transporting Polypeptide-C (SLC21A6) Is a Major Determinant of Rifampin-Mediated Pregnane X Receptor Activation

Rommel G. Tirona, Brenda F. Leake, Allan W. Wolkoff and Richard B. Kim
Journal of Pharmacology and Experimental Therapeutics January 2003, 304 (1) 223-228; DOI: https://doi.org/10.1124/jpet.102.043026

Article Information

vol. 304 no. 1 223-228
DOI 
https://doi.org/10.1124/jpet.102.043026
PubMed 
12490595
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received August 9, 2002
  • Accepted September 13, 2002
  • Published online January 1, 2003.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Rommel G. Tirona1,
  2. Brenda F. Leake1,
  3. Allan W. Wolkoff2 and
  4. Richard B. Kim1
  1. 1Division of Clinical Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee (R.G.T., B.F.L., R.B.K.); and 2Marion Bessin Liver Research Center, Albert Einstein College of Medicine, Bronx, New York (A.W.W.)
  1. Dr. Richard B. Kim, 572 RRB, 23rd Ave. at Pierce Ave., Division of Clinical Pharmacology, Vanderbilt University School of Medicine, Nashville, TN 37232-6602. E-mail:richard.kim{at}vanderbilt.edu
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Research ArticleABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

Human Organic Anion Transporting Polypeptide-C (SLC21A6) Is a Major Determinant of Rifampin-Mediated Pregnane X Receptor Activation

Rommel G. Tirona, Brenda F. Leake, Allan W. Wolkoff and Richard B. Kim
Journal of Pharmacology and Experimental Therapeutics January 1, 2003, 304 (1) 223-228; DOI: https://doi.org/10.1124/jpet.102.043026
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