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Research ArticleTOXICOLOGY

2′-NH2-MPTP [1-Methyl-4-(2′-aminophenyl)-1,2,3,6-tetrahydropyridine] Depletes Serotonin and Norepinephrine in Rats: A Comparison with 2′-CH3-MPTP [1-Methyl-4-(2′-methylphenyl)-1,2,3,6-tetrahydropyridine]

Erica L. Unger, Pascale Mazzola-Pomietto, Dennis L. Murphy and Anne M. Andrews
Journal of Pharmacology and Experimental Therapeutics November 2002, 303 (2) 527-533; DOI: https://doi.org/10.1124/jpet.102.037614

Article Information

vol. 303 no. 2 527-533
DOI 
https://doi.org/10.1124/jpet.102.037614
PubMed 
12388632
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received April 17, 2002
  • Accepted June 20, 2002
  • Published online November 1, 2002.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Erica L. Unger1,
  2. Pascale Mazzola-Pomietto2,
  3. Dennis L. Murphy3 and
  4. Anne M. Andrews1
  1. 1Department of Chemistry, Pennsylvania State University, University Park, Pennsylvania (E.L.U., A.M.A.); 2Institut National de la Santé et de la Recherche Médicale, Marseilles, France (P.M.-P.); and 3Laboratory of Clinical Science, National Institute of Mental Health, Bethesda, Maryland (D.L.M.)
  1. Anne Milasincic Andrews, 152 Davey Laboratory, Department of Chemistry, Pennsylvania State University, University Park, PA 16802. E-mail:ama11{at}psu.edu
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Research ArticleTOXICOLOGY

2′-NH2-MPTP [1-Methyl-4-(2′-aminophenyl)-1,2,3,6-tetrahydropyridine] Depletes Serotonin and Norepinephrine in Rats: A Comparison with 2′-CH3-MPTP [1-Methyl-4-(2′-methylphenyl)-1,2,3,6-tetrahydropyridine]

Erica L. Unger, Pascale Mazzola-Pomietto, Dennis L. Murphy and Anne M. Andrews
Journal of Pharmacology and Experimental Therapeutics November 1, 2002, 303 (2) 527-533; DOI: https://doi.org/10.1124/jpet.102.037614
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