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Journal of Pharmacology and Experimental Therapeutics

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Table of Contents

June 01, 2002; Volume 301,Issue 3

PERSPECTIVES IN PHARMACOLOGY

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    Stress and Cocaine Addiction
    Nick E. Goeders
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 785-789; DOI: https://doi.org/10.1124/jpet.301.3.785
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    Identification of the Endogenous Cannabinoid System through Integrative Pharmacological Approaches
    Billy R. Martin
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 790-796; DOI: https://doi.org/10.1124/jpet.301.3.790

ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

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    Interaction of Human Organic Anion Transporters 2 and 4 with Organic Anion Transport Inhibitors
    Atsushi Enomoto, Michio Takeda, Minoru Shimoda, Shinichi Narikawa, Yukari Kobayashi, Yasuna Kobayashi, Toshinori Yamamoto, Takashi Sekine, Seok Ho Cha, Toshimitsu Niwa and Hitoshi Endou
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 797-802; DOI: https://doi.org/10.1124/jpet.301.3.797
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    Role of PEPT2 in Peptide/Mimetic Trafficking at the Blood-Cerebrospinal Fluid Barrier: Studies in Rat Choroid Plexus Epithelial Cells in Primary Culture
    Cathaleen Shu, Hong Shen, Nathan S. Teuscher, Philip J. Lorenzi, Richard F. Keep and David E. Smith
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 820-829; DOI: https://doi.org/10.1124/jpet.301.3.820
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    Regulation of Blood-Brain Tumor Barrier Permeability by Calcium-Activated Potassium Channels
    Nagendra S. Ningaraj, Mamatha Rao, Kazuhiro Hashizume, Kamlesh Asotra and Keith L. Black
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 838-851; DOI: https://doi.org/10.1124/jpet.301.3.838
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    Effect of Tamoxifen on the Enzymatic Activity of Human Cytochrome CYP2B6
    Chitra Sridar, Ute M. Kent, Lisa M. Notley, Elizabeth M. J. Gillam and Paul F. Hollenberg
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 945-952; DOI: https://doi.org/10.1124/jpet.301.3.945
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    Zidovudine Concentration in Brain Extracellular Fluid Measured by Microdialysis: Steady-State and Transient Results in Rhesus Monkey
    Elizabeth Fox, Peter M. Bungay, John Bacher, Cynthia L. McCully, Robert L. Dedrick and Frank M. Balis
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 1003-1011; DOI: https://doi.org/10.1124/jpet.301.3.1003
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    4-Hydroxylation of Debrisoquine by Human CYP1A1 and Its Inhibition by Quinidine and Quinine
    Camille P. Granvil, Kristopher W. Krausz, Harry V. Gelboin, Jeffrey R. Idle and Frank J. Gonzalez
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 1025-1032; DOI: https://doi.org/10.1124/jpet.301.3.1025
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    Mechanistic Studies on Metabolic Interactions between Gemfibrozil and Statins
    Thomayant Prueksaritanont, Jamie J. Zhao, Bennett Ma, Brad A. Roadcap, Cuyue Tang, Yue Qiu, Lida Liu, Jiunn H. Lin, Paul G. Pearson and Thomas A. Baillie
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 1042-1051; DOI: https://doi.org/10.1124/jpet.301.3.1042
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    Cationic Drug Pharmacokinetics in Diseased Livers Determined by Fibrosis Index, Hepatic Protein Content, Microsomal Activity, and Nature of Drug
    Daniel Y. Hung, Ping Chang, Kee Cheung, Brett McWhinney, Paul P. Masci, Michael Weiss and Michael S. Roberts
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 1079-1087; DOI: https://doi.org/10.1124/jpet.301.3.1079

BEHAVIORAL PHARMACOLOGY

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    Evaluation of CB1 Receptor Knockout Mice in the Morris Water Maze
    S. A. Varvel and A. H. Lichtman
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 915-924; DOI: https://doi.org/10.1124/jpet.301.3.915
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    Effects of Bremazocine on Self-Administration of Smoked Cocaine Base and Orally Delivered Ethanol, Phencyclidine, Saccharin, and Food in Rhesus Monkeys: A Behavioral Economic Analysis
    Kelly P. Cosgrove and Marilyn E. Carroll
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 993-1002; DOI: https://doi.org/10.1124/jpet.301.3.993

CARDIOVASCULAR

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    Differential Rate Responses to Nicotine in Rat Heart: Evidence for Two Classes of Nicotinic Receptors
    Susan Ji, Toshimasa Tosaka, Bernard H. Whitfield, Alexander N. Katchman, Abdurrahman Kandil, Bjoern C. Knollmann and Steven N. Ebert
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 893-899; DOI: https://doi.org/10.1124/jpet.301.3.893
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    Role of Nitric-Oxide Synthase, Free Radicals, and Protein Kinase C δ in Opioid-Induced Cardioprotection
    Hong Yan Zhang, Bradley C. McPherson, Huiping Liu, Timir Baman, Steven S. McPherson, Peter Rock and Zhenhai Yao
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 1012-1019; DOI: https://doi.org/10.1124/jpet.301.3.1012
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    Involvement of TP and EP3 Receptors in Vasoconstrictor Responses to Isoprostanes in Pulmonary Vasculature
    Luke J. Janssen and Tracy Tazzeo
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 1060-1066; DOI: https://doi.org/10.1124/jpet.301.3.1060
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    Intimatan Prevents Arterial and Venous Thrombosis in a Canine Model of Deep Vessel Wall Injury
    James K. Hennan, Ting-Ting Hong, Ardamanpal K. Shergill, Edward M. Driscoll, Alan D. Cardin and Benedict R. Lucchesi
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 1151-1156; DOI: https://doi.org/10.1124/jpet.301.3.1151

CELLULAR AND MOLECULAR

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    β-Eudesmol Induces Neurite Outgrowth in Rat Pheochromocytoma Cells Accompanied by an Activation of Mitogen-Activated Protein Kinase
    Yutaro Obara, Takashi Aoki, Masayoshi Kusano and Yasushi Ohizumi
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 803-811; DOI: https://doi.org/10.1124/jpet.301.3.803
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    The β1 Isoform of Protein Kinase C Mediates the Protective Effects of Epidermal Growth Factor on the Dynamic Assembly of F-Actin Cytoskeleton and Normalization of Calcium Homeostasis in Human Colonic Cells
    A. Banan, J. Z. Fields, A. Farhadi, D. A. Talmage, L. Zhang and A. Keshavarzian
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 852-866; DOI: https://doi.org/10.1124/jpet.301.3.852
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    Direct Examination of Local Regulation of Membrane Activity in Striatal and Prefrontal Cortical Neurons in Vivo Using Simultaneous Intracellular Recording and Microdialysis
    A. R. West, H. Moore and A. A. Grace
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 867-877; DOI: https://doi.org/10.1124/jpet.301.3.867
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    Pharmacological Characterization of the Anandamide Cyclooxygenase Metabolite: Prostaglandin E2 Ethanolamide
    Ruth A. Ross, Susan J. Craib, Lesley A. Stevenson, Roger G. Pertwee, Andrea Henderson, John Toole and Heather C. Ellington
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 900-907; DOI: https://doi.org/10.1124/jpet.301.3.900
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    Temporal Activation of p42/44 Mitogen-Activated Protein Kinase and c-Jun N-Terminal Kinase by Acetaldehyde in Rat Hepatocytes and Its Loss after Chronic Ethanol Exposure
    Youn J. Lee, Annayya R. Aroor and Shivendra D. Shukla
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 908-914; DOI: https://doi.org/10.1124/jpet.301.3.908
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    Toward the Design of Ribonuclease (RNase) Inhibitors: Ion Effects on the Thermodynamics of Binding of 2′-CMP to RNase A
    Shawn D. Spencer, Oluseyi Abdul, Robert J. Schulingkamp and Robert B. Raffa
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 925-929; DOI: https://doi.org/10.1124/jpet.301.3.925
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    Pardaxin Stimulation of Phospholipases A2 and Their Involvement in Exocytosis in PC-12 Cells
    Eugenia Bloch-Shilderman, Saleh Abu-Raya, Victoria Trembovler, Hassia Boschwitz, Arie Gruzman, Michal Linial and Philip Lazarovici
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 953-962; DOI: https://doi.org/10.1124/jpet.301.3.953
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    Allosteric Modulation by Persistent Binding of Xanomeline of the Interaction of Competitive Ligands with the M1 Muscarinic Acetylcholine Receptor
    Jan Jakubı́k, Stanislav Tuček and Esam E. El-Fakahany
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 1033-1041; DOI: https://doi.org/10.1124/jpet.301.3.1033
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    Roles of Guanylate Cyclase in Responses to Myogenic and Neural Nitric Oxide in Canine Lower Esophageal Sphincter
    E. E. Daniel, T. J. Bowes and J. Jury
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 1111-1118; DOI: https://doi.org/10.1124/jpet.301.3.1111

CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY

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    Enhanced Delivery of Drugs to the Liver by Adenovirus-Mediated Heterologous Expression of the Human Oligopeptide Transporter PEPT1
    Hidekazu Toyobuku, Yoshimichi Sai, Ikumi Tamai and Akira Tsuji
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 812-819; DOI: https://doi.org/10.1124/jpet.301.3.812

ENDOCRINE AND REPRODUCTIVE

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    Positron Emission Tomography Shows that Intrathecal Leptin Reaches the Hypothalamus in Baboons
    T. J. McCarthy, W. A. Banks, C. L. Farrell, S. Adamu, C. P. Derdeyn, A. Z. Snyder, R. Laforest, D. C. Litzinger, D. Martin, C. P. LeBel and M. J. Welch
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 878-883; DOI: https://doi.org/10.1124/jpet.301.3.878

GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL

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    Hypoxia Differentially Enhances the Effects of Transforming Growth Factor-β Isoforms on the Synthesis and Secretion of Glycosaminoglycans by Human Lung Fibroblasts
    Eleni Papakonstantinou, Michael Roth, Michael Tamm, Oliver Eickelberg, Andre P. Perruchoud and George Karakiulakis
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 830-837; DOI: https://doi.org/10.1124/jpet.301.3.830
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    Nicotine Increases Hepatic Oxygen Uptake in the Isolated Perfused Rat Liver by Inhibiting Glycolysis
    Brian J. Dewar, Blair U. Bradford and Ronald G. Thurman
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 930-937; DOI: https://doi.org/10.1124/jpet.301.3.930
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    Role of ATP-Sensitive Potassium Channels in Prostaglandin-Mediated Gastroprotection in the Rat
    Brigitta M. Peskar, Karlheinz Ehrlich and Bernhard A. Peskar
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 969-974; DOI: https://doi.org/10.1124/jpet.301.3.969
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    Characterization of Neuromedin U Effects in Canine Smooth Muscle
    Timothy D. Westfall, Gerald P. McCafferty, Mark Pullen, Susan Gruver, Anthony C. Sulpizio, V. Nambi Aiyar, Jyoti Disa, Lisa C. Contino, Ishrat J. Mannan and J. Paul Hieble
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 987-992; DOI: https://doi.org/10.1124/jpet.301.3.987
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    Targeting of Captopril to the Kidney Reduces Renal Angiotensin-Converting Enzyme Activity without Affecting Systemic Blood Pressure
    R. J. Kok, R. F. G. Haverdings, F. Grijpstra, J. Koiter, F. Moolenaar, D. de Zeeuw and D. K. F. Meijer
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 1139-1143; DOI: https://doi.org/10.1124/jpet.301.3.1139

INFLAMMATION AND IMMUNOPHARMACOLOGY

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    Further Pharmacological Evidence of Nuclear Factor-κB Pathway Involvement in Bradykinin B1 Receptor-Sensitized Responses in Human Umbilical Vein
    Sergio Pablo Sardi, Verónica Rey-Ares, Virginia Andrea Pujol-Lereis, Santiago Alejo Serrano and Rodolfo Pedro Rothlin
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 975-980; DOI: https://doi.org/10.1124/jpet.301.3.975
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    Dual Function of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs): Inhibition of Cyclooxygenase and Induction of NSAID-Activated Gene
    Seung Joon Baek, Leigh C. Wilson, Chang-Ho Lee and Thomas E. Eling
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 1126-1131; DOI: https://doi.org/10.1124/jpet.301.3.1126
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    Ranitidine Reduces Ischemia/Reperfusion-Induced Liver Injury in Rats by Inhibiting Neutrophil Activation
    Kenji Okajima, Naoaki Harada and Mitsuhiro Uchiba
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 1157-1165; DOI: https://doi.org/10.1124/jpet.301.3.1157

NEUROPHARMACOLOGY

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    Ifenprodil and Ethanol Enhance NMDA Receptor-Dependent Long-Term Depression
    Adam W. Hendricson, C. L. Alek Miao, Melanie J. Lippmann and Richard A. Morrisett
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 938-944; DOI: https://doi.org/10.1124/jpet.301.3.938
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    CB1 Receptors in the Preoptic Anterior Hypothalamus Regulate WIN 55212-2 [(4,5-Dihydro-2-methyl-4(4-morpholinylmethyl)-1-(1-naphthalenyl-carbonyl)-6H-pyrrolo[3,2,1ij]quinolin-6-one]-Induced Hypothermia
    S. M. Rawls, Jose Cabassa, Ellen B. Geller and Martin W. Adler
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 963-968; DOI: https://doi.org/10.1124/jpet.301.3.963
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    The Arginine-Rich Hexapeptide R4W2 Is a Stereoselective Antagonist at the Vanilloid Receptor 1: A Ca2+ Imaging Study in Adult Rat Dorsal Root Ganglion Neurons
    Herbert M. Himmel, Thomas Kiss, Sebestyén J. Borvendeg, Clemens Gillen and Peter Illes
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 981-986; DOI: https://doi.org/10.1124/jpet.301.3.981
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    Characterization of a Novel Endocannabinoid, Virodhamine, with Antagonist Activity at the CB1 Receptor
    Amy C. Porter, John-Michael Sauer, Michael D. Knierman, Gerald W. Becker, Michael J. Berna, Jingqi Bao, George G. Nomikos, Petra Carter, Frank P. Bymaster, Andrea Baker Leese and Christian C. Felder
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 1020-1024; DOI: https://doi.org/10.1124/jpet.301.3.1020
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    Effects of Ginsenoside Rg2 on Human Neuronal Nicotinic Acetylcholine Receptors
    Francisco Sala, José Mulet, Seok Choi, Se-Yeon Jung, Seung-Yeol Nah, Hyewhon Rhim, Luis Miguel Valor, Manuel Criado and Salvador Sala
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 1052-1059; DOI: https://doi.org/10.1124/jpet.301.3.1052
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    SSR180575 (7-Chloro-N,N,5-trimethyl-4-oxo-3-phenyl-3,5-dihydro-4H-pyridazino[4,5-b]indole-1-acetamide), a Peripheral Benzodiazepine Receptor Ligand, Promotes Neuronal Survival and Repair
    Badia Ferzaz, Emmanuel Brault, Genevieve Bourliaud, Jean-Pierre Robert, Gilles Poughon, Yves Claustre, Franck Marguet, Philippe Liere, Michael Schumacher, Jean-Pierre Nowicki, Jacqueline Fournier, Benoit Marabout, Mireille Sevrin, Pascal George, Philippe Soubrie, Jesus Benavides and Bernard Scatton
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 1067-1078; DOI: https://doi.org/10.1124/jpet.301.3.1067
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    N-n-Alkylnicotinium Analogs, A Novel Class of Nicotinic Receptor Antagonist: Inhibition ofS(−)-Nicotine-Evoked [3H]Dopamine Overflow from Superfused Rat Striatal Slices
    Lincoln H. Wilkins, Aaron Haubner, Joshua T. Ayers, Peter A. Crooks and Linda P. Dwoskin
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 1088-1096; DOI: https://doi.org/10.1124/jpet.301.3.1088
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    Effects of Norepinephrine and Serotonin Transporter Inhibitors on Hyperactivity Induced by Neonatal 6-Hydroxydopamine Lesioning in Rats
    Eugen Davids, Kehong Zhang, Nora S. Kula, Frank I. Tarazi and Ross J. Baldessarini
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 1097-1102; DOI: https://doi.org/10.1124/jpet.301.3.1097
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    Cocaine and Amphetamine Attenuate the Discriminative Stimulus Effects of Naltrexone in Opioid-Dependent Rhesus Monkeys
    Stacy L. Sell and Charles P. France
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 1103-1110; DOI: https://doi.org/10.1124/jpet.301.3.1103
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    Repeated Cocaine Treatment Decreases Whole-Cell Calcium Current in Rat Nucleus Accumbens Neurons
    Xu-Feng Zhang, Donald C. Cooper and Francis J. White
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 1119-1125; DOI: https://doi.org/10.1124/jpet.301.3.1119
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    5-Hydroxytryptamine1A Receptor Occupancy by Novel Full Antagonist 2-[4-[4-(7-Chloro-2,3-dihydro-1,4-benzdioxyn-5-yl)-1-piperazinyl]butyl]-1,2-benzisothiazol-3-(2H)-one-1,1-dioxide: A [11C][O-methyl-3H]-N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide Trihydrochloride (WAY-100635) Positron Emission Tomography Study in Humans
    Eugenii A. Rabiner, Martin R. Wilkins, Federico Turkheimer, Roger N. Gunn, Joanna Udo de Haes, Michiel de Vries and Paul M. Grasby
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 1144-1150; DOI: https://doi.org/10.1124/jpet.301.3.1144
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    Functional Selectivity of Dopamine Receptor Agonists. I. Selective Activation of Postsynaptic Dopamine D2 Receptors Linked to Adenylate Cyclase
    David M. Mottola, Jason D. Kilts, Mechelle M. Lewis, Hilary S. Connery, Q. David Walker, Sara R. Jones, Raymond G. Booth, Deborah K. Hyslop, Monford Piercey, R. Mark Wightman, Cindy P. Lawler, David E. Nichols and Richard B. Mailman
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 1166-1178; DOI: https://doi.org/10.1124/jpet.301.3.1166
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    Functional Selectivity of Dopamine Receptor Agonists. II. Actions of Dihydrexidine in D2L Receptor-Transfected MN9D Cells and Pituitary Lactotrophs
    Jason D. Kilts, Hilary S. Connery, Elaine G. Arrington, Mechelle M. Lewis, Cindy P. Lawler, Gerry S. Oxford, Karen L. O'Malley, Richard D. Todd, Bonita L. Blake, David E. Nichols and Richard B. Mailman
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 1179-1189; DOI: https://doi.org/10.1124/jpet.301.3.1179
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    Persistent Antagonism of Methamphetamine-Induced Dopamine Release in Rats Pretreated with GBR12909 Decanoate
    Michael H. Baumann, Mario A. Ayestas, Lawrence G. Sharpe, David B. Lewis, Kenner C. Rice and Richard B. Rothman
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 1190-1197; DOI: https://doi.org/10.1124/jpet.301.3.1190

TOXICOLOGY

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    β-Lyase-Dependent Attenuation of Cisplatin-Mediated Toxicity by Selenocysteine Se-Conjugates in Renal Tubular Cell Lines
    Martijn Rooseboom, Gerben Schaaf, Jan N. M. Commandeur, Nico P. E. Vermeulen and Johanna Fink-Gremmels
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 884-892; DOI: https://doi.org/10.1124/jpet.301.3.884
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    Skeletal Toxicity Associated with Chronic Ethanol Exposure in a Rat Model Using Total Enteral Nutrition
    Elizabeth C. Brown, Daniel S. Perrien, Terry W. Fletcher, David J. Irby, James Aronson, Guan G. Gao, William J. Hogue, Robert A. Skinner, Larry J. Suva, Martin J. J. Ronis, Reza Hakkak, Thomas M. Badger and Charles K. Lumpkin
    Journal of Pharmacology and Experimental Therapeutics June 2002, 301 (3) 1132-1138; DOI: https://doi.org/10.1124/jpet.301.3.1132
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Journal of Pharmacology and Experimental Therapeutics: 301 (3)
Journal of Pharmacology and Experimental Therapeutics
Vol. 301, Issue 3
1 Jun 2002
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  • PERSPECTIVES IN PHARMACOLOGY
  • ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION
  • BEHAVIORAL PHARMACOLOGY
  • CARDIOVASCULAR
  • CELLULAR AND MOLECULAR
  • CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY
  • ENDOCRINE AND REPRODUCTIVE
  • GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL
  • INFLAMMATION AND IMMUNOPHARMACOLOGY
  • NEUROPHARMACOLOGY
  • TOXICOLOGY
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  • Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.
  • Functional Selectivity and Classical Concepts of Quantitative Pharmacology
  • Abl Protein-Tyrosine Kinase Inhibitor STI571 Inhibits In Vitro Signal Transduction Mediated by c-Kit and Platelet-Derived Growth Factor Receptors
  • The Prediction of Human Pharmacokinetic Parameters from Preclinical and In Vitro Metabolism Data
  • A METHOD FOR DETERMINING LOSS OF PAIN SENSATION
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