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Research ArticleCELLULAR AND MOLECULAR

Allosteric Modulation of Muscarinic Receptor Signaling: Alcuronium-Induced Conversion of Pilocarpine from an Agonist into an Antagonist

Katrin Zahn, Niels Eckstein, Christian Tränkle, Wolfgang Sadée and Klaus Mohr
Journal of Pharmacology and Experimental Therapeutics May 2002, 301 (2) 720-728; DOI: https://doi.org/10.1124/jpet.301.2.720

Article Information

vol. 301 no. 2 720-728
DOI 
https://doi.org/10.1124/jpet.301.2.720
PubMed 
11961078
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received November 26, 2001
  • Accepted January 25, 2002
  • Published online May 1, 2002.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Katrin Zahn1,
  2. Niels Eckstein1,2,
  3. Christian Tränkle1,
  4. Wolfgang Sadée2 and
  5. Klaus Mohr1
  1. 1Department of Pharmacology and Toxicology, Institute of Pharmacy, University of Bonn, Germany (K.Z., N.E., C.T., K.M.); and 2Department of Biopharmaceutical Sciences and Pharmaceutical Chemistry, University of California, San Francisco, California (N.E., W.S.)
  1. Dr. Klaus Mohr, Department of Pharmacology and Toxicology, Institute of Pharmacy, University of Bonn, An der Immenburg 4, D-53121 Bonn, Germany. E-mail: K.Mohr{at}uni-bonn.de
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Research ArticleCELLULAR AND MOLECULAR

Allosteric Modulation of Muscarinic Receptor Signaling: Alcuronium-Induced Conversion of Pilocarpine from an Agonist into an Antagonist

Katrin Zahn, Niels Eckstein, Christian Tränkle, Wolfgang Sadée and Klaus Mohr
Journal of Pharmacology and Experimental Therapeutics May 1, 2002, 301 (2) 720-728; DOI: https://doi.org/10.1124/jpet.301.2.720
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