Skip to main content
Advertisement

Main menu

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET

User menu

  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
Journal of Pharmacology and Experimental Therapeutics
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET
  • My alerts
  • Log in
  • My Cart
Journal of Pharmacology and Experimental Therapeutics

Advanced Search

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Visit jpet on Facebook
  • Follow jpet on Twitter
  • Follow jpet on LinkedIn
Research ArticleABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

Amodiaquine Clearance and Its Metabolism toN-Desethylamodiaquine Is Mediated by CYP2C8: A New High Affinity and Turnover Enzyme-Specific Probe Substrate

Xue-Qing Li, Anders Björkman, Tommy B. Andersson, Marianne Ridderström and Collen M. Masimirembwa
Journal of Pharmacology and Experimental Therapeutics February 2002, 300 (2) 399-407; DOI: https://doi.org/10.1124/jpet.300.2.399
Xue-Qing Li
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Anders Björkman
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Tommy B. Andersson
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Marianne Ridderström
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Collen M. Masimirembwa
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF
Loading

Article Information

vol. 300 no. 2 399-407
DOI 
https://doi.org/10.1124/jpet.300.2.399
PubMed 
11805197

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received July 25, 2001
  • Accepted October 5, 2001
  • Published online February 1, 2002.

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Xue-Qing Li1,2,
  2. Anders Björkman2,
  3. Tommy B. Andersson1,
  4. Marianne Ridderström1 and
  5. Collen M. Masimirembwa1,2
  1. 1Drug Metabolism and Pharmacokinetics and Bioanalytical Chemistry, AstraZeneca Research and Development, Mölndal, Sweden (X.-Q.L., T.B.A., M.R., C.M.M.); and 2Unit of Infectious Diseases, Karolinska Institute Hospital, Stockholm, Sweden (X.-Q.L., A.B., C.M.M.)
  1. Dr. Collen Masimirembwa, DMPK and Bioanalytical Chemistry, AstraZeneca R&D Mölndal, S-431 83 Mölndal, Sweden. E-mail:collen.masimirembwa{at}astrazeneca.com
View Full Text

Statistics from Altmetric.com

Article usage

Article usage: January 2002 to September 2023

AbstractFullPdf
Jan 2002222778
Feb 2002177692
Mar 200292554
Apr 200233238
May 200232858
Jun 200211516
Jul 200211625
Aug 20024167
Sep 200202922
Oct 200231919
Nov 2002199
Dec 200231817
Jan 200331323
Feb 200303457
Mar 200323346
Apr 200312021
May 200311419
Jun 200341528
Jul 2003114120
Aug 200372812
Sep 200383427
Oct 200385042
Nov 2003164229
Dec 200384335
Jan 2004144125
Feb 2004115440
Mar 2004134333
Apr 2004134731
May 2004134338
Jun 2004106840
Jul 2004177329
Aug 2004175741
Sep 2004155428
Oct 2004105427
Nov 2004187519
Dec 2004164322
Jan 2005174959
Feb 2005145121
Mar 2005144820
Apr 200564153
May 2005105740
Jun 200583533
Jul 200585430
Aug 2005125444
Sep 200573425
Oct 200546652
Nov 200564928
Dec 200554622
Jan 200686841
Feb 200664314
Mar 200657923
Apr 2006115242
May 200693825
Jun 200623918
Jul 200651917
Aug 2006103620
Sep 200672620
Oct 2006132130
Nov 2006103730
Dec 200662419
Jan 2007122441
Feb 200775050
Mar 200793634
Apr 2007123736
May 200794139
Jun 2007104539
Jul 2007153350
Aug 2007174339
Sep 2007104221
Oct 2007165045
Nov 200783923
Dec 2007103819
Jan 200862623
Feb 2008124530
Mar 2008195141
Apr 2008124235
May 2008143216
Jun 200893431
Jul 2008282720
Aug 2008303224
Sep 2008161922
Oct 2008233643
Nov 2008424342
Dec 2008132023
Jan 200972823
Feb 2009232527
Mar 2009133544
Apr 2009162735
May 2009121522
Jun 2009153331
Jul 2009993226
Aug 2009162926
Sep 2009202023
Oct 2009161920
Nov 2009302323
Dec 2009151714
Jan 2010213339
Feb 2010304128
Mar 2010243624
Apr 2010204017
May 2010244817
Jun 2010153722
Jul 2010174028
Aug 2010163024
Sep 2010254834
Oct 2010264324
Nov 2010143518
Dec 2010172826
Jan 2011143423
Feb 2011232520
Mar 2011123215
Apr 2011243229
May 2011272829
Jun 2011292132
Jul 2011161617
Aug 2011101021
Sep 2011142139
Oct 2011263934
Nov 2011202216
Dec 2011181727
Jan 2012182742
Feb 2012153022
Mar 2012263236
Apr 2012172325
May 2012203243
Jun 2012262935
Jul 2012173735
Aug 2012232242
Sep 2012232232
Oct 2012403333
Nov 2012131823
Dec 2012152728
Jan 2013112026
Feb 2013152118
Mar 2013122317
Apr 2013202424
May 2013304267
Jun 2013142119
Jul 2013192725
Aug 2013131619
Sep 2013201517
Oct 2013141321
Nov 2013102235
Dec 2013212226
Jan 2014111428
Feb 201415813
Mar 2014152329
Apr 2014181723
May 201491727
Jun 2014281932
Jul 2014202523
Aug 201481628
Sep 2014192017
Oct 2014171714
Nov 2014181715
Dec 2014151520
Jan 2015121923
Feb 201551222
Mar 2015162619
Apr 2015132115
May 2015131516
Jun 2015192815
Jul 2015131920
Aug 201591312
Sep 2015213425
Oct 2015161614
Nov 2015197335
Dec 2015231915
Jan 2016141733
Feb 2016182521
Mar 2016422520
Apr 2016534316
May 2016172316
Jun 2016306134
Jul 2016182027
Aug 2016162328
Sep 2016251925
Oct 2016104821
Nov 20161718838
Dec 201626515
Jan 201722919
Feb 201702516
Mar 201773413
Apr 20175187
May 201792918
Jun 2017153231
Jul 201733220
Aug 201754618
Sep 2017103429
Oct 201753619
Nov 20172012358
Dec 201774722
Jan 201862416
Feb 201865619
Mar 201826025
Apr 201804526
May 201883423
Jun 201824034
Jul 201851938
Aug 201852732
Sep 201842326
Oct 201862933
Nov 201889266
Dec 2018252511
Jan 20192565
Feb 20192291
Mar 20193243
Apr 20194562
May 20192459
Jun 20193979
Jul 201951010
Aug 20194089
Sep 201967610
Oct 2019291011
Nov 20196186
Dec 2019421211
Jan 20203252
Feb 202031134
Mar 202039112
Apr 20202236
May 202015549
Jun 20205153
Jul 202034413
Aug 202015911
Sep 20201843
Oct 2020301010
Nov 20204129
Dec 20203143
Jan 2021132310
Feb 202123187
Mar 20215443
Apr 20213164
May 202161128
Jun 2021441110
Jul 20212748
Aug 202122142
Sep 20213063
Oct 202161119
Nov 202145109
Dec 20215165
Jan 20222245
Feb 20224564
Mar 20223536
Apr 20225066
May 20224035
Jun 20223562
Jul 20222432
Aug 20224369
Sep 20223751
Oct 202239148
Nov 20224214
Dec 20223721
Jan 20234974
Feb 20231785
Mar 20232643
Apr 20234742
May 20233072
Jun 20231252
Jul 20236433
Aug 20232773
Sep 2023630

PreviousNext
Back to top

In this issue

Journal of Pharmacology and Experimental Therapeutics: 300 (2)
Journal of Pharmacology and Experimental Therapeutics
Vol. 300, Issue 2
1 Feb 2002
  • Table of Contents
  • About the Cover
  • Index by author
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for sharing this Journal of Pharmacology and Experimental Therapeutics article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
Amodiaquine Clearance and Its Metabolism toN-Desethylamodiaquine Is Mediated by CYP2C8: A New High Affinity and Turnover Enzyme-Specific Probe Substrate
(Your Name) has forwarded a page to you from Journal of Pharmacology and Experimental Therapeutics
(Your Name) thought you would be interested in this article in Journal of Pharmacology and Experimental Therapeutics.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Research ArticleABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

Amodiaquine Clearance and Its Metabolism toN-Desethylamodiaquine Is Mediated by CYP2C8: A New High Affinity and Turnover Enzyme-Specific Probe Substrate

Xue-Qing Li, Anders Björkman, Tommy B. Andersson, Marianne Ridderström and Collen M. Masimirembwa
Journal of Pharmacology and Experimental Therapeutics February 1, 2002, 300 (2) 399-407; DOI: https://doi.org/10.1124/jpet.300.2.399

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero

Share
Research ArticleABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

Amodiaquine Clearance and Its Metabolism toN-Desethylamodiaquine Is Mediated by CYP2C8: A New High Affinity and Turnover Enzyme-Specific Probe Substrate

Xue-Qing Li, Anders Björkman, Tommy B. Andersson, Marianne Ridderström and Collen M. Masimirembwa
Journal of Pharmacology and Experimental Therapeutics February 1, 2002, 300 (2) 399-407; DOI: https://doi.org/10.1124/jpet.300.2.399
Reddit logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Materials and Methods
    • Results
    • Discussion
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF

Related Articles

Cited By...

More in this TOC Section

  • Transport Is Not Rate-Limiting in Morphine Glucuronidation in the Single-Pass Perfused Rat Liver Preparation
  • Enhanced Hepatic Uptake and Bioactivity of Type α1(I) Collagen Gene Promoter-Specific Triplex-Forming Oligonucleotides after Conjugation with Cholesterol
  • Characterization of P-glycoprotein Inhibition by Major Cannabinoids from Marijuana
Show more ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

Similar Articles

Advertisement
  • Home
  • Alerts
Facebook   Twitter   LinkedIn   RSS

Navigate

  • Current Issue
  • Fast Forward by date
  • Fast Forward by section
  • Latest Articles
  • Archive
  • Search for Articles
  • Feedback
  • ASPET

More Information

  • About JPET
  • Editorial Board
  • Instructions to Authors
  • Submit a Manuscript
  • Customized Alerts
  • RSS Feeds
  • Subscriptions
  • Permissions
  • Terms & Conditions of Use

ASPET's Other Journals

  • Drug Metabolism and Disposition
  • Molecular Pharmacology
  • Pharmacological Reviews
  • Pharmacology Research & Perspectives
ISSN 1521-0103 (Online)

Copyright © 2023 by the American Society for Pharmacology and Experimental Therapeutics