Interindividual Variability in Acetaminophen Glucuronidation by Human Liver Microsomes: Identification of Relevant Acetaminophen UDP-Glucuronosyltransferase Isoforms

Dr. Michael H. Court, Department of Pharmacology and Experimental Therapeutics, Tufts University, 136 Harrison Avenue, Boston, MA 02111. E-mail: michael.court{at}tufts.edu

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	Abstract	Full	Pdf
Nov 2001	43	66	116
Dec 2001	12	55	62
Jan 2002	10	60	71
Feb 2002	3	46	34
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May 2002	4	32	17
Jun 2002	2	17	13
Jul 2002	1	29	52
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Jan 2003	5	23	27
Feb 2003	2	25	23
Mar 2003	3	26	28
Apr 2003	3	27	31
May 2003	0	15	18
Jun 2003	1	26	30
Jul 2003	9	35	20
Aug 2003	5	29	13
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Oct 2003	9	40	24
Nov 2003	6	36	16
Dec 2003	11	49	18
Jan 2004	8	49	21
Feb 2004	10	48	21
Mar 2004	12	66	23
Apr 2004	15	60	30
May 2004	14	62	29
Jun 2004	19	45	16
Jul 2004	9	30	11
Aug 2004	18	55	35
Sep 2004	15	72	27
Oct 2004	21	52	14
Nov 2004	19	68	27
Dec 2004	12	44	21
Jan 2005	12	56	32
Feb 2005	16	68	32
Mar 2005	13	54	23
Apr 2005	7	41	20
May 2005	5	36	13
Jun 2005	6	39	21
Jul 2005	10	28	18
Aug 2005	6	47	23
Sep 2005	9	30	18
Oct 2005	9	45	26
Nov 2005	5	32	11
Dec 2005	8	29	15
Jan 2006	7	29	17
Feb 2006	6	38	19
Mar 2006	0	31	24
Apr 2006	3	37	27
May 2006	3	22	17
Jun 2006	4	24	20
Jul 2006	4	26	25
Aug 2006	3	32	14
Sep 2006	2	21	14
Oct 2006	9	39	23
Nov 2006	7	43	23
Dec 2006	7	34	20
Jan 2007	8	21	20
Feb 2007	3	22	22
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Apr 2007	4	29	28
May 2007	3	36	25
Jun 2007	8	32	14
Jul 2007	8	39	32
Aug 2007	11	29	10
Sep 2007	7	36	31
Oct 2007	2	35	25
Nov 2007	10	23	24
Dec 2007	0	20	14
Jan 2008	1	22	17
Feb 2008	4	24	10
Mar 2008	0	23	22
Apr 2008	12	26	16
May 2008	6	23	21
Jun 2008	9	25	11
Jul 2008	3	30	30
Aug 2008	11	28	17
Sep 2008	13	26	22
Oct 2008	13	21	15
Nov 2008	12	28	14
Dec 2008	7	13	7
Jan 2009	5	24	14
Feb 2009	8	20	19
Mar 2009	11	20	27
Apr 2009	9	22	16
May 2009	7	32	20
Jun 2009	10	13	14
Jul 2009	9	19	10
Aug 2009	4	20	12
Sep 2009	10	25	12
Oct 2009	15	25	21
Nov 2009	12	15	14
Dec 2009	9	13	15
Jan 2010	15	10	14
Feb 2010	15	13	13
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Apr 2010	10	9	10
May 2010	17	19	17
Jun 2010	22	22	16
Jul 2010	10	14	14
Aug 2010	10	13	15
Sep 2010	9	21	18
Oct 2010	9	17	17
Nov 2010	10	33	30
Dec 2010	3	10	11
Jan 2011	17	17	19
Feb 2011	7	11	14
Mar 2011	18	15	26
Apr 2011	15	14	25
May 2011	10	25	20
Jun 2011	11	25	24
Jul 2011	14	22	29
Aug 2011	12	11	12
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Oct 2011	16	19	24
Nov 2011	9	21	32
Dec 2011	38	43	22
Jan 2012	9	17	18
Feb 2012	14	19	27
Mar 2012	17	31	30
Apr 2012	12	17	36
May 2012	11	20	27
Jun 2012	10	13	25
Jul 2012	25	22	27
Aug 2012	14	23	27
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Oct 2012	22	16	28
Nov 2012	39	24	35
Dec 2012	20	13	33
Jan 2013	21	17	26
Feb 2013	15	16	23
Mar 2013	26	18	26
Apr 2013	21	18	19
May 2013	20	32	49
Jun 2013	15	12	17
Jul 2013	8	12	15
Aug 2013	6	9	13
Sep 2013	10	5	15
Oct 2013	6	21	37
Nov 2013	4	21	24
Dec 2013	18	12	22
Jan 2014	8	17	26
Feb 2014	14	11	26
Mar 2014	9	16	31
Apr 2014	15	14	36
May 2014	13	20	33
Jun 2014	9	20	13
Jul 2014	13	22	16
Aug 2014	6	47	22
Sep 2014	7	36	28
Oct 2014	12	14	20
Nov 2014	5	20	12
Dec 2014	4	16	9
Jan 2015	20	17	16
Feb 2015	11	11	11
Mar 2015	9	17	21
Apr 2015	6	7	12
May 2015	5	18	14
Jun 2015	9	10	15
Jul 2015	15	13	26
Aug 2015	40	11	8
Sep 2015	8	16	18
Oct 2015	15	15	15
Nov 2015	10	38	20
Dec 2015	3	7	4
Jan 2016	11	10	20
Feb 2016	6	22	23
Mar 2016	8	22	26
Apr 2016	13	23	27
May 2016	16	22	36
Jun 2016	15	17	24
Jul 2016	13	14	10
Aug 2016	16	15	16
Sep 2016	3	12	13
Oct 2016	5	22	13
Nov 2016	0	14	5
Dec 2016	6	40	20
Jan 2017	10	21	21
Feb 2017	6	11	17
Mar 2017	6	35	26
Apr 2017	9	18	10
May 2017	4	20	10
Jun 2017	2	18	11
Jul 2017	3	20	5
Aug 2017	2	18	13
Sep 2017	4	22	7
Oct 2017	12	13	20
Nov 2017	6	122	15
Dec 2017	2	21	17
Jan 2018	3	13	12
Feb 2018	2	18	23
Mar 2018	4	44	22
Apr 2018	5	30	20
May 2018	2	18	15
Jun 2018	5	19	5
Jul 2018	3	12	12
Aug 2018	3	12	10
Sep 2018	4	29	17
Oct 2018	2	18	7
Nov 2018	2	35	8
Dec 2018	29	14	8
Jan 2019	61	10	5
Feb 2019	13	2	3
Mar 2019	28	7	6
Apr 2019	19	8	4
May 2019	29	7	7
Jun 2019	43	6	10
Jul 2019	29	4	3
Aug 2019	27	7	9
Sep 2019	22	3	2
Oct 2019	45	17	8
Nov 2019	51	12	9
Dec 2019	58	22	9
Jan 2020	24	9	10
Feb 2020	18	6	3
Mar 2020	28	17	6
Apr 2020	42	10	5
May 2020	35	5	3
Jun 2020	16	11	6
Jul 2020	19	3	2
Aug 2020	40	17	10
Sep 2020	15	9	1
Oct 2020	27	23	4
Nov 2020	20	9	2
Dec 2020	24	3	0
Jan 2021	19	48	5
Feb 2021	13	42	3
Mar 2021	8	6	2
Apr 2021	16	7	0
May 2021	44	20	2
Jun 2021	9	21	1
Jul 2021	22	14	5
Aug 2021	15	28	4
Sep 2021	6	15	2
Oct 2021	21	8	4
Nov 2021	39	11	1
Dec 2021	37	23	2
Jan 2022	28	11	8
Feb 2022	42	8	3
Mar 2022	17	8	2
Apr 2022	22	0	1
May 2022	26	3	1
Jun 2022	25	6	4