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Research ArticleABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

Interindividual Variability in Acetaminophen Glucuronidation by Human Liver Microsomes: Identification of Relevant Acetaminophen UDP-Glucuronosyltransferase Isoforms

Michael H. Court, Su X. Duan, Lisa L. von Moltke, David J. Greenblatt, Christopher J. Patten, John O. Miners and Peter I. Mackenzie
Journal of Pharmacology and Experimental Therapeutics December 2001, 299 (3) 998-1006;
Michael H. Court
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Su X. Duan
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Lisa L. von Moltke
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David J. Greenblatt
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Christopher J. Patten
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John O. Miners
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Peter I. Mackenzie
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Article Information

vol. 299 no. 3 998-1006
PubMed 
11714888

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received July 2, 2001
  • Accepted August 21, 2001
  • Published online December 1, 2001.

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Michael H. Court1,
  2. Su X. Duan1,
  3. Lisa L. von Moltke2,
  4. David J. Greenblatt2,
  5. Christopher J. Patten3,
  6. John O. Miners4 and
  7. Peter I. Mackenzie4
  1. 1Molecular Pharmacogenetics (M.H.C., S.X.D.) and 2Clinical Pharmacology (L.L.v.M., D.J.G.) Laboratories, Department of Pharmacology and Experimental Therapeutics, Tufts University School of Medicine, Boston, Massachusetts; 3Gentest (C.J.P.), Woburn, Massachusetts; and 4Department of Clinical Pharmacology (J.O.M., P.I.M.), Flinders University School of Medicine, Bedford Park, South Australia
  1. Dr. Michael H. Court, Department of Pharmacology and Experimental Therapeutics, Tufts University, 136 Harrison Avenue, Boston, MA 02111. E-mail: michael.court{at}tufts.edu
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Journal of Pharmacology and Experimental Therapeutics: 299 (3)
Journal of Pharmacology and Experimental Therapeutics
Vol. 299, Issue 3
1 Dec 2001
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Research ArticleABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

Interindividual Variability in Acetaminophen Glucuronidation by Human Liver Microsomes: Identification of Relevant Acetaminophen UDP-Glucuronosyltransferase Isoforms

Michael H. Court, Su X. Duan, Lisa L. von Moltke, David J. Greenblatt, Christopher J. Patten, John O. Miners and Peter I. Mackenzie
Journal of Pharmacology and Experimental Therapeutics December 1, 2001, 299 (3) 998-1006;

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Research ArticleABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

Interindividual Variability in Acetaminophen Glucuronidation by Human Liver Microsomes: Identification of Relevant Acetaminophen UDP-Glucuronosyltransferase Isoforms

Michael H. Court, Su X. Duan, Lisa L. von Moltke, David J. Greenblatt, Christopher J. Patten, John O. Miners and Peter I. Mackenzie
Journal of Pharmacology and Experimental Therapeutics December 1, 2001, 299 (3) 998-1006;
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