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Research ArticleABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

Rifampin Is a Selective, Pleiotropic Inducer of Drug Metabolism Genes in Human Hepatocytes: Studies with cDNA and Oligonucleotide Expression Arrays

James M. Rae, Michael D. Johnson, Marc E. Lippman and David A. Flockhart
Journal of Pharmacology and Experimental Therapeutics December 2001, 299 (3) 849-857;

Article Information

vol. 299 no. 3 849-857
PubMed 
11714868
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received May 1, 2001
  • Accepted August 21, 2001
  • Published online December 1, 2001.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. James M. Rae1,1,
  2. Michael D. Johnson2,
  3. Marc E. Lippman1,2,3 and
  4. David A. Flockhart1,3
  1. Departments of 1Pharmacology (J.M.R., D.A.F.), 2Oncology (M.D.J., M.E.L.), and 3Medicine (M.E.L., D.A.F.), Division of Clinical Pharmacology, Georgetown University Medical Center, Washington, DC
  1. Dr. James Michael Rae, Department of Internal Medicine, University of Michigan Med Sci 1, Room 5312, 1500 East Medical Center Dr., Ann Arbor, MI 48109. E-mail:jimmyrae{at}umich.edu
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Research ArticleABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

Rifampin Is a Selective, Pleiotropic Inducer of Drug Metabolism Genes in Human Hepatocytes: Studies with cDNA and Oligonucleotide Expression Arrays

James M. Rae, Michael D. Johnson, Marc E. Lippman and David A. Flockhart
Journal of Pharmacology and Experimental Therapeutics December 1, 2001, 299 (3) 849-857;
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