Toxicity of Alpidem, a Peripheral Benzodiazepine Receptor Ligand, but Not Zolpidem, in Rat Hepatocytes: Role of Mitochondrial Permeability Transition and Metabolic Activation

	Abstract	Full	Pdf
Oct 2001	26	34	51
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Feb 2002	3	7	4
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Apr 2002	2	10	7
May 2002	2	24	19
Jun 2002	0	17	10
Jul 2002	0	17	20
Aug 2002	1	6	14
Sep 2002	0	6	10
Oct 2002	3	18	17
Nov 2002	0	7	11
Dec 2002	1	5	7
Jan 2003	2	22	24
Feb 2003	1	24	20
Mar 2003	0	14	12
Apr 2003	3	10	11
May 2003	0	8	13
Jun 2003	0	9	9
Jul 2003	15	21	13
Aug 2003	6	20	7
Sep 2003	10	23	10
Oct 2003	11	29	14
Nov 2003	16	19	6
Dec 2003	17	30	13
Jan 2004	16	32	20
Feb 2004	7	28	19
Mar 2004	7	47	14
Apr 2004	22	35	16
May 2004	17	59	23
Jun 2004	12	43	23
Jul 2004	22	37	14
Aug 2004	13	39	31
Sep 2004	13	26	17
Oct 2004	19	39	40
Nov 2004	9	50	17
Dec 2004	7	32	17
Jan 2005	10	40	19
Feb 2005	9	28	6
Mar 2005	8	40	42
Apr 2005	3	29	20
May 2005	6	27	29
Jun 2005	11	34	22
Jul 2005	6	18	20
Aug 2005	3	20	12
Sep 2005	6	32	36
Oct 2005	3	17	19
Nov 2005	6	29	19
Dec 2005	4	21	18
Jan 2006	9	32	29
Feb 2006	8	31	19
Mar 2006	3	20	14
Apr 2006	3	38	36
May 2006	9	19	24
Jun 2006	7	18	22
Jul 2006	4	17	16
Aug 2006	1	14	18
Sep 2006	1	18	15
Oct 2006	9	35	44
Nov 2006	4	25	22
Dec 2006	4	18	20
Jan 2007	1	19	17
Feb 2007	8	20	16
Mar 2007	1	29	31
Apr 2007	8	20	15
May 2007	10	34	34
Jun 2007	7	20	14
Jul 2007	13	15	29
Aug 2007	9	19	26
Sep 2007	4	23	15
Oct 2007	8	21	21
Nov 2007	9	19	12
Dec 2007	3	15	13
Jan 2008	4	19	18
Feb 2008	6	15	10
Mar 2008	16	15	14
Apr 2008	11	16	14
May 2008	19	27	21
Jun 2008	22	24	17
Jul 2008	22	24	16
Aug 2008	17	21	4
Sep 2008	22	22	32
Oct 2008	32	16	16
Nov 2008	10	21	13
Dec 2008	7	13	6
Jan 2009	22	17	12
Feb 2009	15	16	14
Mar 2009	19	18	7
Apr 2009	5	14	11
May 2009	14	15	8
Jun 2009	12	19	7
Jul 2009	7	16	8
Aug 2009	13	14	6
Sep 2009	9	10	10
Oct 2009	14	8	6
Nov 2009	17	15	13
Dec 2009	8	6	7
Jan 2010	10	17	9
Feb 2010	19	5	11
Mar 2010	16	11	10
Apr 2010	6	16	7
May 2010	8	9	4
Jun 2010	10	5	4
Jul 2010	15	21	13
Aug 2010	13	11	7
Sep 2010	11	20	6
Oct 2010	12	24	9
Nov 2010	8	11	5
Dec 2010	13	28	5
Jan 2011	10	15	13
Feb 2011	14	9	5
Mar 2011	15	23	12
Apr 2011	12	25	16
May 2011	19	22	21
Jun 2011	10	13	7
Jul 2011	18	19	16
Aug 2011	19	17	12
Sep 2011	20	34	14
Oct 2011	20	32	22
Nov 2011	13	21	13
Dec 2011	16	23	9
Jan 2012	10	16	6
Feb 2012	12	25	28
Mar 2012	18	22	11
Apr 2012	21	14	11
May 2012	15	28	18
Jun 2012	13	24	16
Jul 2012	24	24	18
Aug 2012	19	24	15
Sep 2012	24	19	16
Oct 2012	9	16	25
Nov 2012	29	15	19
Dec 2012	9	10	11
Jan 2013	10	12	14
Feb 2013	9	7	20
Mar 2013	16	9	38
Apr 2013	17	9	43
May 2013	9	12	45
Jun 2013	10	8	32
Jul 2013	8	12	35
Aug 2013	9	4	44
Sep 2013	7	7	33
Oct 2013	5	9	35
Nov 2013	9	8	38
Dec 2013	7	13	23
Jan 2014	10	6	26
Feb 2014	8	5	20
Mar 2014	14	6	33
Apr 2014	16	14	26
May 2014	18	10	21
Jun 2014	7	9	19
Jul 2014	12	13	32
Aug 2014	11	5	13
Sep 2014	4	6	15
Oct 2014	11	7	24
Nov 2014	19	4	31
Dec 2014	8	7	45
Jan 2015	4	6	16
Feb 2015	6	8	18
Mar 2015	7	10	23
Apr 2015	10	11	20
May 2015	15	8	23
Jun 2015	3	11	19
Jul 2015	11	4	30
Aug 2015	10	10	23
Sep 2015	9	7	27
Oct 2015	18	3	32
Nov 2015	5	21	26
Dec 2015	47	9	30
Jan 2016	11	7	44
Feb 2016	2	13	23
Mar 2016	7	5	33
Apr 2016	9	14	30
May 2016	13	9	28
Jun 2016	8	6	36
Jul 2016	15	14	48
Aug 2016	11	32	52
Sep 2016	3	7	57
Oct 2016	8	2	70
Nov 2016	9	9	71
Dec 2016	10	14	55
Jan 2017	1	7	59
Feb 2017	1	17	51
Mar 2017	2	43	52
Apr 2017	0	219	69
May 2017	17	187	52
Jun 2017	1	132	25
Jul 2017	3	63	24
Aug 2017	0	8	23
Sep 2017	1	5	35
Oct 2017	1	11	41
Nov 2017	1	74	61
Dec 2017	1	238	60
Jan 2018	2	137	40
Feb 2018	6	174	47
Mar 2018	3	68	29
Apr 2018	1	72	48
May 2018	3	73	25
Jun 2018	2	78	22
Jul 2018	0	22	28
Aug 2018	4	10	24
Sep 2018	1	16	25
Oct 2018	1	87	32
Nov 2018	3	53	32
Dec 2018	75	9	7
Jan 2019	94	0	4
Feb 2019	76	4	1
Mar 2019	56	0	1
Apr 2019	66	9	8
May 2019	47	1	1
Jun 2019	33	3	4
Jul 2019	46	1	4
Aug 2019	33	3	5
Sep 2019	46	1	2
Oct 2019	39	1	5
Nov 2019	42	4	8
Dec 2019	37	3	1
Jan 2020	43	6	6
Feb 2020	19	3	2
Mar 2020	45	1	7
Apr 2020	89	0	2
May 2020	80	1	1
Jun 2020	33	6	5
Jul 2020	40	0	0
Aug 2020	15	0	3
Sep 2020	40	0	1
Oct 2020	19	3	1
Nov 2020	37	0	0
Dec 2020	41	0	5
Jan 2021	26	3	4
Feb 2021	16	2	2
Mar 2021	42	3	3
Apr 2021	42	1	1
May 2021	180	2	8
Jun 2021	42	1	2
Jul 2021	24	4	8
Aug 2021	24	2	1
Sep 2021	28	2	2
Oct 2021	39	4	2
Nov 2021	30	5	1
Dec 2021	66	2	1
Jan 2022	28	2	0
Feb 2022	29	4	0
Mar 2022	26	6	5
Apr 2022	148	3	12
May 2022	42	2	2
Jun 2022	38	4	5
Jul 2022	20	4	0
Aug 2022	33	5	4
Sep 2022	18	2	3
Oct 2022	58	2	3
Nov 2022	34	1	1
Dec 2022	42	4	4
Jan 2023	38	2	1
Feb 2023	25	2	2
Mar 2023	16	1	0