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Research ArticleABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

Rational Use of in Vitro P-glycoprotein Assays in Drug Discovery

Joseph W. Polli, Stephen A. Wring, Joan E. Humphreys, Liyue Huang, Jonathon B. Morgan, Lindsey O. Webster and Cosette S. Serabjit-Singh
Journal of Pharmacology and Experimental Therapeutics November 2001, 299 (2) 620-628;
Joseph W. Polli
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Stephen A. Wring
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Joan E. Humphreys
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Liyue Huang
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Jonathon B. Morgan
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Lindsey O. Webster
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Cosette S. Serabjit-Singh
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Article Information

vol. 299 no. 2 620-628
PubMed 
11602674

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received May 16, 2001
  • Accepted July 17, 2001
  • Published online November 1, 2001.

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Joseph W. Polli,
  2. Stephen A. Wring,
  3. Joan E. Humphreys,
  4. Liyue Huang,
  5. Jonathon B. Morgan,
  6. Lindsey O. Webster and
  7. Cosette S. Serabjit-Singh
  1. Preclinical Drug Metabolism and Pharmacokinetics, GlaxoSmithKline, Inc., Research Triangle Park, North Carolina
  1. Joseph W. Polli, Ph.D., GlaxoSmithKline, Inc., P.O. Box 17709, Room MAI-A3666.3E, Research Triangle Park, NC 27709. E-mail: JP16063{at}gsk.com
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Journal of Pharmacology and Experimental Therapeutics: 299 (2)
Journal of Pharmacology and Experimental Therapeutics
Vol. 299, Issue 2
1 Nov 2001
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Research ArticleABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

Rational Use of in Vitro P-glycoprotein Assays in Drug Discovery

Joseph W. Polli, Stephen A. Wring, Joan E. Humphreys, Liyue Huang, Jonathon B. Morgan, Lindsey O. Webster and Cosette S. Serabjit-Singh
Journal of Pharmacology and Experimental Therapeutics November 1, 2001, 299 (2) 620-628;

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Research ArticleABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

Rational Use of in Vitro P-glycoprotein Assays in Drug Discovery

Joseph W. Polli, Stephen A. Wring, Joan E. Humphreys, Liyue Huang, Jonathon B. Morgan, Lindsey O. Webster and Cosette S. Serabjit-Singh
Journal of Pharmacology and Experimental Therapeutics November 1, 2001, 299 (2) 620-628;
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