Improved Pharmacokinetic Properties of a Polyethylene Glycol-Modified Form of Interferon-β-1a with Preserved in Vitro Bioactivity

R. Blake Pepinsky; Doreen J. LePage; Alan Gill; Abhijit Chakraborty; Sujata Vaidyanathan; Marie Green; Darren P. Baker; Eric Whalley; Paula S. Hochman; Pauline Martin

Article Information

vol. 297 no. 3 1059-1066

PubMed

11356929

Published By

American Society for Pharmacology and Experimental Therapeutics

Print ISSN

0022-3565

Online ISSN

1521-0103

History

Received January 9, 2001
Accepted February 18, 2001
Published online June 1, 2001.

The American Society for Pharmacology and Experimental Therapeutics

Author Information

R. Blake Pepinsky,
Doreen J. LePage,
Alan Gill,
Abhijit Chakraborty,
Sujata Vaidyanathan,
Marie Green,
Darren P. Baker,
Eric Whalley,
Paula S. Hochman and
Pauline Martin

Biogen, Inc., Cambridge, Massachusetts

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