Primaquine-Induced Hemolytic Anemia: Formation and Hemotoxicity of the Arylhydroxylamine Metabolite 6-Methoxy-8-hydroxylaminoquinoline

Laura J. C. Bolchoz; Robert A. Budinsky; David C. McMillan; David J. Jollow

Article Information

vol. 297 no. 2 509-515

PubMed

11303037

Published By

American Society for Pharmacology and Experimental Therapeutics

Print ISSN

0022-3565

Online ISSN

1521-0103

History

Received September 6, 2000
Accepted January 16, 2001
Published online May 1, 2001.

The American Society for Pharmacology and Experimental Therapeutics

Author Information

Laura J. C. Bolchoz,
Robert A. Budinsky1,
David C. McMillan and
David J. Jollow

Department of Pharmacology, Medical University of South Carolina, Charleston, South Carolina

View Full Text

Statistics from Altmetric.com

Article usage

Article usage: April 2001 to June 2022

	Abstract	Full	Pdf
Apr 2001	14	19	19
May 2001	10	7	15
Jun 2001	1	9	7
Jul 2001	1	4	3
Aug 2001	1	5	3
Sep 2001	0	6	1
Oct 2001	0	5	4
Nov 2001	2	4	9
Dec 2001	0	1	0
Jan 2002	0	1	0
Feb 2002	1	5	2
Mar 2002	3	12	4
Apr 2002	4	13	5
May 2002	1	12	16
Jun 2002	0	5	0
Jul 2002	0	10	8
Aug 2002	0	8	7
Sep 2002	0	3	2
Oct 2002	0	8	7
Nov 2002	2	12	10
Dec 2002	1	8	12
Jan 2003	4	17	86
Feb 2003	0	33	95
Mar 2003	0	3	2
Apr 2003	1	6	6
May 2003	0	1	3
Jun 2003	0	7	8
Jul 2003	9	11	9
Aug 2003	9	22	3
Sep 2003	10	33	4
Oct 2003	9	28	4
Nov 2003	12	47	12
Dec 2003	11	26	5
Jan 2004	10	40	9
Feb 2004	38	55	22
Mar 2004	12	47	7
Apr 2004	12	38	13
May 2004	17	38	11
Jun 2004	12	39	7
Jul 2004	16	44	12
Aug 2004	21	44	14
Sep 2004	12	61	4
Oct 2004	20	66	14
Nov 2004	21	50	7
Dec 2004	20	42	13
Jan 2005	21	87	21
Feb 2005	11	39	8
Mar 2005	13	22	7
Apr 2005	3	21	0
May 2005	2	39	22
Jun 2005	5	21	9
Jul 2005	5	21	7
Aug 2005	10	21	20
Sep 2005	4	18	7
Oct 2005	2	21	8
Nov 2005	2	16	5
Dec 2005	5	20	15
Jan 2006	5	40	3
Feb 2006	5	29	8
Mar 2006	4	22	5
Apr 2006	3	14	10
May 2006	2	12	7
Jun 2006	5	10	1
Jul 2006	4	8	3
Aug 2006	2	7	5
Sep 2006	1	13	9
Oct 2006	5	38	14
Nov 2006	7	6	6
Dec 2006	7	12	5
Jan 2007	2	14	14
Feb 2007	6	16	12
Mar 2007	7	15	11
Apr 2007	4	27	10
May 2007	4	21	11
Jun 2007	6	15	6
Jul 2007	2	21	10
Aug 2007	2	16	12
Sep 2007	11	24	18
Oct 2007	1	37	7
Nov 2007	3	25	11
Dec 2007	2	17	12
Jan 2008	2	10	8
Feb 2008	1	16	15
Mar 2008	1	24	9
Apr 2008	2	15	9
May 2008	1	21	12
Jun 2008	5	27	11
Jul 2008	2	19	9
Aug 2008	8	10	8
Sep 2008	19	10	3
Oct 2008	11	24	6
Nov 2008	10	21	11
Dec 2008	4	28	9
Jan 2009	4	13	7
Feb 2009	6	32	8
Mar 2009	5	16	10
Apr 2009	11	33	19
May 2009	5	21	15
Jun 2009	4	30	11
Jul 2009	1	17	13
Aug 2009	3	19	12
Sep 2009	9	16	11
Oct 2009	9	22	8
Nov 2009	6	17	0
Dec 2009	5	5	4
Jan 2010	9	24	18
Feb 2010	12	29	16
Mar 2010	13	34	20
Apr 2010	9	30	12
May 2010	7	31	19
Jun 2010	3	25	22
Jul 2010	13	22	13
Aug 2010	4	34	15
Sep 2010	8	37	10
Oct 2010	8	51	21
Nov 2010	10	42	16
Dec 2010	3	32	13
Jan 2011	4	48	20
Feb 2011	4	44	30
Mar 2011	7	56	10
Apr 2011	2	45	14
May 2011	8	41	21
Jun 2011	8	35	16
Jul 2011	7	31	23
Aug 2011	10	31	16
Sep 2011	7	36	13
Oct 2011	10	48	23
Nov 2011	9	59	35
Dec 2011	7	48	19
Jan 2012	4	20	19
Feb 2012	9	46	32
Mar 2012	13	52	36
Apr 2012	11	86	24
May 2012	7	68	13
Jun 2012	14	62	17
Jul 2012	11	71	31
Aug 2012	4	34	21
Sep 2012	8	13	18
Oct 2012	1	46	31
Nov 2012	10	49	51
Dec 2012	6	24	22
Jan 2013	10	27	18
Feb 2013	12	36	27
Mar 2013	5	41	14
Apr 2013	10	33	6
May 2013	9	32	36
Jun 2013	0	24	7
Jul 2013	3	19	16
Aug 2013	5	33	12
Sep 2013	1	36	17
Oct 2013	9	28	11
Nov 2013	10	23	5
Dec 2013	3	22	18
Jan 2014	2	23	17
Feb 2014	13	30	24
Mar 2014	6	39	19
Apr 2014	10	17	13
May 2014	13	33	12
Jun 2014	6	21	10
Jul 2014	4	22	17
Aug 2014	12	29	8
Sep 2014	2	39	11
Oct 2014	4	24	13
Nov 2014	5	15	3
Dec 2014	3	11	7
Jan 2015	10	15	2
Feb 2015	0	16	2
Mar 2015	3	23	16
Apr 2015	2	34	11
May 2015	4	40	9
Jun 2015	13	31	6
Jul 2015	3	20	4
Aug 2015	1	23	7
Sep 2015	5	22	7
Oct 2015	8	27	8
Nov 2015	6	25	10
Dec 2015	12	36	8
Jan 2016	6	24	8
Feb 2016	6	35	10
Mar 2016	8	54	24
Apr 2016	4	29	6
May 2016	11	14	6
Jun 2016	6	20	26
Jul 2016	5	11	16
Aug 2016	5	15	9
Sep 2016	4	18	6
Oct 2016	3	17	14
Nov 2016	18	28	7
Dec 2016	5	21	7
Jan 2017	3	9	3
Feb 2017	3	36	3
Mar 2017	3	40	9
Apr 2017	1	16	6
May 2017	2	12	3
Jun 2017	3	18	4
Jul 2017	4	9	3
Aug 2017	2	17	3
Sep 2017	2	7	14
Oct 2017	0	21	6
Nov 2017	4	21	7
Dec 2017	8	24	8
Jan 2018	3	15	9
Feb 2018	1	16	4
Mar 2018	1	22	5
Apr 2018	0	27	9
May 2018	1	37	3
Jun 2018	0	18	3
Jul 2018	3	20	5
Aug 2018	2	19	6
Sep 2018	1	22	1
Oct 2018	0	15	3
Nov 2018	0	13	2
Dec 2018	20	3	7
Jan 2019	15	1	1
Feb 2019	4	3	1
Mar 2019	22	0	0
Apr 2019	41	0	0
May 2019	27	5	5
Jun 2019	13	3	3
Jul 2019	4	0	0
Aug 2019	21	4	2
Sep 2019	17	0	0
Oct 2019	14	0	0
Nov 2019	40	2	2
Dec 2019	11	1	2
Jan 2020	11	2	1
Feb 2020	10	0	0
Mar 2020	5	0	0
Apr 2020	9	0	0
May 2020	12	2	2
Jun 2020	10	1	1
Jul 2020	3	2	0
Aug 2020	2	0	1
Sep 2020	3	0	0
Oct 2020	20	0	1
Nov 2020	5	0	0
Dec 2020	6	2	0
Jan 2021	13	3	0
Feb 2021	8	1	0
Mar 2021	8	1	2
Apr 2021	34	1	0
May 2021	61	5	3
Jun 2021	5	1	0
Jul 2021	8	1	0
Aug 2021	8	5	0
Sep 2021	8	1	0
Oct 2021	6	1	0
Nov 2021	18	1	0
Dec 2021	9	0	0
Jan 2022	14	1	0
Feb 2022	10	1	1
Mar 2022	5	1	0
Apr 2022	23	2	2
May 2022	15	0	4
Jun 2022	12	3	2