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Journal of Pharmacology and Experimental Therapeutics

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Table of Contents

January 01, 2001; Volume 296,Issue 1

PERSPECTIVES IN PHARMACOLOGY

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    Cellular Thiols and Reactive Oxygen Species in Drug-Induced Apoptosis
    Warren Davis, Ze'ev Ronai and Kenneth D. Tew
    Journal of Pharmacology and Experimental Therapeutics January 2001, 296 (1) 1-6;

ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

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    Modulation of Intestinal Permeability by Nitric Oxide Donors: Implications in Intestinal Delivery of Poorly Absorbable Drugs
    Akira Yamamoto, Hiroyuki Tatsumi, Masato Maruyama, Tomomi Uchiyama, Naoki Okada and Takuya Fujita
    Journal of Pharmacology and Experimental Therapeutics January 2001, 296 (1) 84-90;
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    Hepatic Uptake of Synthetic Chlorogenic Acid Derivatives by the Organic Anion Transport Proteins
    Dietmar Schwab, Andreas W. Herling, Horst Hemmerle, Gerrit Schubert, Bruno Hagenbuch and Hans-Joerg Burger
    Journal of Pharmacology and Experimental Therapeutics January 2001, 296 (1) 91-98;
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    Scopolamine Bioavailability in Combined Oral and Transdermal Delivery
    Zohar Nachum, Baruch Shahal, Avi Shupak, Orna Spitzer, Adi Gonen, Itzchak Beiran, Haim Lavon, Mirit Eynan, Shlomit Dachir and Aharon Levy
    Journal of Pharmacology and Experimental Therapeutics January 2001, 296 (1) 121-123;
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    Enhanced Delivery of Doxorubicin into the Brain via a Peptide-Vector-Mediated Strategy: Saturation Kinetics and Specificity
    Christophe Rousselle, Maria Smirnova, Philippe Clair, Jeanne-Marie Lefauconnier, Alain Chavanieu, Bernard Calas, Jean-Michel Scherrmann and Jamal Temsamani
    Journal of Pharmacology and Experimental Therapeutics January 2001, 296 (1) 124-131;
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    A Novel Zidovudine Uptake System in Microglia
    MeeRa Hong, Lyanne Schlichter and Reina Bendayan
    Journal of Pharmacology and Experimental Therapeutics January 2001, 296 (1) 141-149;
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    Interactions between Cimetidine, Nitrofurantoin, and Probenecid Active Transport into Rat Milk
    Phillip M. Gerk, Cheah Y. Oo, Earl W. Paxton, Jeffrey A. Moscow and Patrick J. McNamara
    Journal of Pharmacology and Experimental Therapeutics January 2001, 296 (1) 175-180;
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    Effects of Benzyl Isothiocyanate on Rat and Human Cytochromes P450: Identification of Metabolites Formed by P450 2B1
    Theunis C. Goosen, Danielle E. Mills and Paul F. Hollenberg
    Journal of Pharmacology and Experimental Therapeutics January 2001, 296 (1) 198-206;

CARDIOVASCULAR

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    A Metabolic Fragment of Bradykinin, Arg-Pro-Pro-Gly-Phe, Protects against the Deleterious Effects of Lipopolysaccharide in Rats
    Thomas A. Morinelli, Jerry G. Webb, Ayad A. Jaffa, Philip J. Privitera and Harry S. Margolius
    Journal of Pharmacology and Experimental Therapeutics January 2001, 296 (1) 71-76;
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    Chronic Type IV Phosphodiesterase Inhibition Protects Glomerular Filtration Rate and Renal and Mesenteric Blood Flow in a Zymosan-Induced Model of Multiple Organ Dysfunction Syndrome Treated with Norepinephrine
    Neal J. Thomas, Joseph A. Carcillo, William A. Herzer, Zaichuan Mi and Edwin K. Jackson
    Journal of Pharmacology and Experimental Therapeutics January 2001, 296 (1) 168-174;

CELLULAR AND MOLECULAR

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    Different Binding Modes of Amphibian and Human Corticotropin-Releasing Factor Type 1 and Type 2 Receptors: Evidence for Evolutionary Differences
    Frank M. Dautzenberg, Gabrielle Py-Lang, Jacqueline Higelin, Christophe Fischer, Matthew B. Wright and Gerda Huber
    Journal of Pharmacology and Experimental Therapeutics January 2001, 296 (1) 113-120;
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    In Vivo Demonstration of α1A-Adrenoceptor Subtype Selectivity of KMD-3213 in Rat Tissues
    Shizuo Yamada, Takashi Okura and Ryohei Kimura
    Journal of Pharmacology and Experimental Therapeutics January 2001, 296 (1) 160-167;
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    α2-Adrenoceptor Agonists Inhibit Vitreal Glutamate and Aspartate Accumulation and Preserve Retinal Function after Transient Ischemia
    John E. Donello, Edwin U. Padillo, Michelle L. Webster, Larry A. Wheeler and Daniel W. Gil
    Journal of Pharmacology and Experimental Therapeutics January 2001, 296 (1) 216-223;

CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY

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    Pyrrolo-1,5-benzoxazepines Induce Apoptosis in Chronic Myelogenous Leukemia (CML) Cells by Bypassing the Apoptotic Suppressor Bcr-Abl
    Margaret M. Mc Gee, Giuseppe Campiani, Anna Ramunno, Caterina Fattorusso, Vito Nacci, Mark Lawler, D. Clive Williams and Daniela M. Zisterer
    Journal of Pharmacology and Experimental Therapeutics January 2001, 296 (1) 31-40;

ENDOCRINE AND REPRODUCTIVE

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    A New Hypoglycemic Agent, JTT-608, Evokes Protein Kinase A-Mediated Ca2+ Signaling in Rat Islet β-Cells: Strict Regulation by Glucose, Link to Insulin Release, and Cooperation with Glucagon-Like Peptide-1(7-36)amide and Pituitary Adenylate Cyclase-Activating Polypeptide
    Suzuko Hashiguchi, Toshihiko Yada and Terukatsu Arima
    Journal of Pharmacology and Experimental Therapeutics January 2001, 296 (1) 22-30;
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    Stimulatory Effect of Clofibrate and Gemfibrozil Administration on the Formation of Fatty Acid Esters of Estradiol by Rat Liver Microsomes
    Shiyao Xu, Bao Ting Zhu and Allan H. Conney
    Journal of Pharmacology and Experimental Therapeutics January 2001, 296 (1) 188-197;

GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL

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    FR167653, a p38 Mitogen-Activated Protein Kinase Inhibitor, Prevents Helicobacter pylori-Induced Gastritis in Mongolian Gerbils
    Satoru Takahashi, Yoshihiro Keto, Takuya Fujita, Tomomi Uchiyama and Akira Yamamoto
    Journal of Pharmacology and Experimental Therapeutics January 2001, 296 (1) 48-56;

INFLAMMATION AND IMMUNOPHARMACOLOGY

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    Antianalgesic Action of Nociceptin Originating in the Brain Is Mediated by Spinal Prostaglandin E2 in Mice
    Jodie J. Rady, William B. Campbell and James M. Fujimoto
    Journal of Pharmacology and Experimental Therapeutics January 2001, 296 (1) 7-14;
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    Adenosine Kinase Inhibitor GP515 Improves Experimental Colitis in Mice
    Britta Siegmund, Florian Rieder, Stefan Albrich, Katrin Wolf, Christoph Bidlingmaier, Gary S. Firestein, David Boyle, Hans-Anton Lehr, Florian Loher, Gunther Hartmann, Stefan Endres and Andreas Eigler
    Journal of Pharmacology and Experimental Therapeutics January 2001, 296 (1) 99-105;
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    S-Adenosyl-l-homocysteine Hydrolase Inhibitor Mediates Immunosuppressive Effects in Vivo: Suppression of Delayed Type Hypersensitivity Ear Swelling and Peptidoglycan Polysaccharide-Induced Arthritis
    Yoshihisa Saso, Elaine M. Conner, Bradley R. Teegarden and Chong-Sheng Yuan
    Journal of Pharmacology and Experimental Therapeutics January 2001, 296 (1) 106-112;
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    Luteolin Inhibits an Endotoxin-Stimulated Phosphorylation Cascade and Proinflammatory Cytokine Production in Macrophages
    Angeliki Xagorari, Andreas Papapetropoulos, Antonis Mauromatis, Michalis Economou, Theodore Fotsis and Charis Roussos
    Journal of Pharmacology and Experimental Therapeutics January 2001, 296 (1) 181-187;
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    Acute Effects of 3,4-Methylenedioxymethamphetamine Alone and in Combination with Ethanol on the Immune System in Humans
    Roberta Pacifici, Piergiorgio Zuccaro, Candido Hernández López, Simona Pichini, Simonetta Di Carlo, Magi Farré, Pere Nolasc Roset, Jordi Ortuño, Jordi Segura and Rafael de La Torre
    Journal of Pharmacology and Experimental Therapeutics January 2001, 296 (1) 207-215;

NEUROPHARMACOLOGY

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    Adrenal Tyrosine Hydroxylase Activity and Gene Expression Are Increased by Intraventricular Administration of Nicotine
    Carol R. Sterling and A. William Tank
    Journal of Pharmacology and Experimental Therapeutics January 2001, 296 (1) 15-21;
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    mGluR5 Antagonists 2-Methyl-6-(phenylethynyl)-pyridine and (E)-2-Methyl-6-(2-phenylethenyl)-pyridine Reduce Traumatic Neuronal Injury In Vitro and In Vivo by AntagonizingN-Methyl-d-aspartate Receptors
    Vilen A. Movsesyan, Deirdre M. O'Leary, Lei Fan, Weili Bao, Paul G. M. Mullins, Susan M. Knoblach and Alan I. Faden
    Journal of Pharmacology and Experimental Therapeutics January 2001, 296 (1) 41-47;
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    A Peptide Derived from Activity-Dependent Neuroprotective Protein (ADNP) Ameliorates Injury Response in Closed Head Injury in Mice
    Liana Beni-Adani, Illana Gozes, Yoram Cohen, Yaniv Assaf, Ruth A. Steingart, Douglas E. Brenneman, Oded Eizenberg, Victoria Trembolver and Esther Shohami
    Journal of Pharmacology and Experimental Therapeutics January 2001, 296 (1) 57-63;
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    Correlation between the Release of the Sympathetic Neurotransmitter ATP and Soluble Nucleotidases from the Guinea Pig Vas Deferens
    Svetlana Mihaylova-Todorova, Latchezar D. Todorov and David P. Westfall
    Journal of Pharmacology and Experimental Therapeutics January 2001, 296 (1) 64-70;
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    Ethanol Potentiation of Glycine-Induced Responses in Dissociated Neurons of Rat Ventral Tegmental Area
    Jiang Hong Ye, Liang Tao, Jun Ren, Rebecca Schaefer, Kresimir Krnjević, Philip L. Liu, Dolores A. Schiller and Joseph J. McArdle
    Journal of Pharmacology and Experimental Therapeutics January 2001, 296 (1) 77-83;
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    Influence of Gender and Sex Hormones on Nicotine Acute Pharmacological Effects in Mice
    M. Imad Damaj
    Journal of Pharmacology and Experimental Therapeutics January 2001, 296 (1) 132-140;
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    Use of Trifluoroperazine Isolates a [3H]Ifenprodil Binding Site in Rat Brain Membranes with the Pharmacology of the Voltage-Independent Ifenprodil Site onN-Methyl-d-aspartate Receptors Containing NR2B Subunits
    Linda L. Coughenour and Bridget M. Barr
    Journal of Pharmacology and Experimental Therapeutics January 2001, 296 (1) 150-159;

Erratum

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    Journal of Pharmacology and Experimental Therapeutics January 2001, 296 (1) 224;
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In this issue

Journal of Pharmacology and Experimental Therapeutics: 296 (1)
Journal of Pharmacology and Experimental Therapeutics
Vol. 296, Issue 1
1 Jan 2001
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  • PERSPECTIVES IN PHARMACOLOGY
  • ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION
  • CARDIOVASCULAR
  • CELLULAR AND MOLECULAR
  • CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY
  • ENDOCRINE AND REPRODUCTIVE
  • GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL
  • INFLAMMATION AND IMMUNOPHARMACOLOGY
  • NEUROPHARMACOLOGY
  • Erratum
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  • Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.
  • Functional Selectivity and Classical Concepts of Quantitative Pharmacology
  • Abl Protein-Tyrosine Kinase Inhibitor STI571 Inhibits In Vitro Signal Transduction Mediated by c-Kit and Platelet-Derived Growth Factor Receptors
  • The Prediction of Human Pharmacokinetic Parameters from Preclinical and In Vitro Metabolism Data
  • A METHOD FOR DETERMINING LOSS OF PAIN SENSATION
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