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Research ArticleNEUROPHARMACOLOGY

Pharmacological Actions of a Novel, High-Affinity, and Selective Human Dopamine D3 Receptor Antagonist, SB-277011-A

Charlie Reavill, Stephen G. Taylor, Martyn D. Wood, Tracey Ashmeade, Nigel E. Austin, Kim Y. Avenell, Izzy Boyfield, Clive L. Branch, Jackie Cilia, Martyn C. Coldwell, Michael S. Hadley, A. Jackie Hunter, Phil Jeffrey, Frances Jewitt, Christopher N. Johnson, Declan N. C. Jones, Andrew D. Medhurst, Derek N. Middlemiss, David J. Nash, Graham J. Riley, Carol Routledge, Geoff Stemp, Kevin M. Thewlis, Brenda Trail, Antonio K. K. Vong and Jim J. Hagan
Journal of Pharmacology and Experimental Therapeutics September 2000, 294 (3) 1154-1165;
Charlie Reavill
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Stephen G. Taylor
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Martyn D. Wood
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Tracey Ashmeade
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Nigel E. Austin
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Kim Y. Avenell
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Izzy Boyfield
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Clive L. Branch
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Jackie Cilia
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Martyn C. Coldwell
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Michael S. Hadley
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A. Jackie Hunter
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Phil Jeffrey
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Frances Jewitt
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Christopher N. Johnson
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Declan N. C. Jones
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Andrew D. Medhurst
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Derek N. Middlemiss
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David J. Nash
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Graham J. Riley
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Carol Routledge
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Geoff Stemp
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Kevin M. Thewlis
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Brenda Trail
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Antonio K. K. Vong
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Jim J. Hagan
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Article Information

vol. 294 no. 3 1154-1165
PubMed 
10945872

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received February 18, 2000
  • Accepted May 16, 2000
  • Published online September 1, 2000.

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Charlie Reavill1,1,
  2. Stephen G. Taylor1,
  3. Martyn D. Wood1,
  4. Tracey Ashmeade1,
  5. Nigel E. Austin3,
  6. Kim Y. Avenell1,
  7. Izzy Boyfield1,
  8. Clive L. Branch2,
  9. Jackie Cilia1,
  10. Martyn C. Coldwell1,
  11. Michael S. Hadley2,
  12. A. Jackie Hunter1,
  13. Phil Jeffrey3,
  14. Frances Jewitt1,
  15. Christopher N. Johnson2,
  16. Declan N. C. Jones1,
  17. Andrew D. Medhurst1,
  18. Derek N. Middlemiss1,
  19. David J. Nash2,
  20. Graham J. Riley1,
  21. Carol Routledge,
  22. Geoff Stemp2,
  23. Kevin M. Thewlis2,
  24. Brenda Trail1,
  25. Antonio K. K. Vong2 and
  26. Jim J. Hagan1
  1. Departments of 1Neuroscience Research (C.R., S.G.T., M.D.W., T.A., K.Y.A., I.B., J.C., M.C.C., A.J.H., F.J., D.N.C.J., A.D.M., D.N.M., G.J.R., C.R., B.T., J.J.H.), 2Discovery Chemistry (C.L.B., M.S.H., C.N.J., D.J.N., G.S., K.M.T., A.K.K.V.), and 3Drug Metabolism and Pharmacokinetics (N.E.A., P.J.), SmithKline Beecham Pharmaceuticals, New Frontiers Science Park, Harlow, Essex, United Kingdom
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    Journal of Pharmacology and Experimental Therapeutics: 294 (3)
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    1 Sep 2000
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    Research ArticleNEUROPHARMACOLOGY

    Pharmacological Actions of a Novel, High-Affinity, and Selective Human Dopamine D3 Receptor Antagonist, SB-277011-A

    Charlie Reavill, Stephen G. Taylor, Martyn D. Wood, Tracey Ashmeade, Nigel E. Austin, Kim Y. Avenell, Izzy Boyfield, Clive L. Branch, Jackie Cilia, Martyn C. Coldwell, Michael S. Hadley, A. Jackie Hunter, Phil Jeffrey, Frances Jewitt, Christopher N. Johnson, Declan N. C. Jones, Andrew D. Medhurst, Derek N. Middlemiss, David J. Nash, Graham J. Riley, Carol Routledge, Geoff Stemp, Kevin M. Thewlis, Brenda Trail, Antonio K. K. Vong and Jim J. Hagan
    Journal of Pharmacology and Experimental Therapeutics September 1, 2000, 294 (3) 1154-1165;

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    Research ArticleNEUROPHARMACOLOGY

    Pharmacological Actions of a Novel, High-Affinity, and Selective Human Dopamine D3 Receptor Antagonist, SB-277011-A

    Charlie Reavill, Stephen G. Taylor, Martyn D. Wood, Tracey Ashmeade, Nigel E. Austin, Kim Y. Avenell, Izzy Boyfield, Clive L. Branch, Jackie Cilia, Martyn C. Coldwell, Michael S. Hadley, A. Jackie Hunter, Phil Jeffrey, Frances Jewitt, Christopher N. Johnson, Declan N. C. Jones, Andrew D. Medhurst, Derek N. Middlemiss, David J. Nash, Graham J. Riley, Carol Routledge, Geoff Stemp, Kevin M. Thewlis, Brenda Trail, Antonio K. K. Vong and Jim J. Hagan
    Journal of Pharmacology and Experimental Therapeutics September 1, 2000, 294 (3) 1154-1165;
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