Table of Contents

NEUROPHARMACOLOGY

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  Neuroprotective Effects of LY379268, a Selective mGlu2/3 Receptor Agonist: Investigations into Possible Mechanism of Action In Vivo

  Ann Bond, Nicole M. Jones, Caroline A. Hicks, Gary M. Whiffin, Mark A. Ward, Michael F. O'Neill, Ann E. Kingston, James A. Monn, Paul L. Ornstein, Darryle D. Schoepp, David Lodge and Michael J. O'Neill

  Journal of Pharmacology and Experimental Therapeutics September 2000, 294 (3) 800-809;
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  The Effects of High-Dose Methamphetamine in the Aging Rat: Differential Reinforcement of Low-Rate 72-s Schedule Behavior and Neurochemistry

  Karen E. Sabol, Jerry B. Richards and Kenneth Yung

  Journal of Pharmacology and Experimental Therapeutics September 2000, 294 (3) 850-863;
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  Actions of the Anticonvulsant Remacemide Metabolite AR-R12495AA on Afferent-Evoked Spinal Synaptic Transmission In Vitro and on Models of Acute and Chronic Inflammation in the Rat

  Aziz U. R. Asghar, Sibte S. Hasan and Anne E. King

  Journal of Pharmacology and Experimental Therapeutics September 2000, 294 (3) 876-883;
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  Antagonism of the Discriminative Stimulus Effects of Positive γ-Aminobutyric Acid_A Modulators in Rhesus Monkeys Discriminating Midazolam

  Snjezana Lelas, Lisa R. Gerak and Charles P. France

  Journal of Pharmacology and Experimental Therapeutics September 2000, 294 (3) 902-908;
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  Enhanced Anticonvulsant Activity of Ganaxolone after Neurosteroid Withdrawal in a Rat Model of Catamenial Epilepsy

  Doodipala S. Reddy and Michael A. Rogawski

  Journal of Pharmacology and Experimental Therapeutics September 2000, 294 (3) 909-915;
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  Methocinnamox Is a Potent, Long-Lasting, and Selective Antagonist of Morphine-Mediated Antinociception in the Mouse: Comparison with Clocinnamox, β-Funaltrexamine, and β-Chlornaltrexamine

  Jillian H. Broadbear, Tina L. Sumpter, Timothy F. Burke, Stephen M Husbands, John W. Lewis, James H. Woods and John R. Traynor

  Journal of Pharmacology and Experimental Therapeutics September 2000, 294 (3) 933-940;
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  Antagonism of δ₂-Opioid Receptors by Naltrindole-5′-isothiocyanate Attenuates Heroin Self-Administration but Not Antinociception in Rats

  Thomas J. Martin, Susy A. Kim, David G. Cannon, Glen M. Sizemore, Di Bian, Frank Porreca and James E. Smith

  Journal of Pharmacology and Experimental Therapeutics September 2000, 294 (3) 975-982;
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  Muscarinic Cholinergic Modulation of Prepulse Inhibition of the Acoustic Startle Reflex

  Carrie K. Jones and Harlan E. Shannon

  Journal of Pharmacology and Experimental Therapeutics September 2000, 294 (3) 1017-1023;
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  Uptake of Imipramine in Rat Liver Lysosomes In Vitro and Its Inhibition by Basic Drugs

  Junko Ishizaki, Koichi Yokogawa, Fujio Ichimura and Shoji Ohkuma

  Journal of Pharmacology and Experimental Therapeutics September 2000, 294 (3) 1088-1098;
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  Differential Mechanisms Mediating Descending Pain Controls for Antinociception Induced by Supraspinally Administered Endomorphin-1 and Endomorphin-2 in the Mouse

  Masahiro Ohsawa, Hirokazu Mizoguchi, Minoru Narita, Mei Chu, Hiroshi Nagase and Leon F. Tseng

  Journal of Pharmacology and Experimental Therapeutics September 2000, 294 (3) 1106-1111;
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  Evidence That Nicotinic α₇ Receptors Are Not Involved in the Hyperlocomotor and Rewarding Effects of Nicotine

  Andrew J. Grottick, Gerhard Trube, William A. Corrigall, Joerg Huwyler, Parichehr Malherbe, Rene Wyler and Guy A. Higgins

  Journal of Pharmacology and Experimental Therapeutics September 2000, 294 (3) 1112-1119;
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  Pharmacological Actions of a Novel, High-Affinity, and Selective Human Dopamine D₃ Receptor Antagonist, SB-277011-A

  Charlie Reavill, Stephen G. Taylor, Martyn D. Wood, Tracey Ashmeade, Nigel E. Austin, Kim Y. Avenell, Izzy Boyfield, Clive L. Branch, Jackie Cilia, Martyn C. Coldwell, Michael S. Hadley, A. Jackie Hunter, Phil Jeffrey, Frances Jewitt, Christopher N. Johnson, Declan N. C. Jones, Andrew D. Medhurst, Derek N. Middlemiss, David J. Nash, Graham J. Riley, Carol Routledge, Geoff Stemp, Kevin M. Thewlis, Brenda Trail, Antonio K. K. Vong and Jim J. Hagan

  Journal of Pharmacology and Experimental Therapeutics September 2000, 294 (3) 1154-1165;
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  Acute and Chronic Administration of the Selective D₃Receptor Antagonist SB-277011-A Alters Activity of Midbrain Dopamine Neurons in Rats: An In Vivo Electrophysiological Study

  Charles R. Ashby, Yoshio Minabe, Geoff Stemp, Jim J. Hagan and Derek N. Middlemiss

  Journal of Pharmacology and Experimental Therapeutics September 2000, 294 (3) 1166-1174;
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  BU48: A Novel Buprenorphine Analog That Exhibits δ-Opioid-Mediated Convulsions but Not δ-Opioid-Mediated Antinociception in Mice

  Daniel C. Broom, Li Guo, Andrew Coop, Stephen M. Husbands, John W. Lewis, James H. Woods and John R. Traynor

  Journal of Pharmacology and Experimental Therapeutics September 2000, 294 (3) 1195-1200;
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  Cannabinoid Properties of Methylfluorophosphonate Analogs

  Billy R. Martin, Irina Beletskaya, Gray Patrick, Reneé Jefferson, Ramona Winckler, Dale G. Deutsch, Vincenzo Di Marzo, Olivier Dasse, Ann Mahadevan and Raj K. Razdan

  Journal of Pharmacology and Experimental Therapeutics September 2000, 294 (3) 1209-1218;