Major Role of Human Liver Microsomal Cytochrome P450 2C9 (CYP2C9) in the Oxidative Metabolism of Celecoxib, a Novel Cyclooxygenase-II Inhibitor

Cuyue Tang; Magang Shou; Qin Mei; Thomas H. Rushmore; A. David Rodrigues

Article Information

vol. 293 no. 2 453-459

PubMed

10773015

Published By

American Society for Pharmacology and Experimental Therapeutics

Print ISSN

0022-3565

Online ISSN

1521-0103

History

Received October 21, 1999
Accepted January 17, 2000
Published online May 1, 2000.

The American Society for Pharmacology and Experimental Therapeutics

Author Information

Cuyue Tang,
Magang Shou,
Qin Mei,
Thomas H. Rushmore and
A. David Rodrigues

Department of Drug Metabolism, Merck Research Laboratories, West Point, Pennsylvania

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