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Research ArticleABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

Role of Drug Release and Liposome-Mediated Drug Delivery in Governing the Therapeutic Activity of Liposomal Mitoxantrone Used to Treat Human A431 and LS180 Solid Tumors

Howard J. Lim, Dana Masin, Natashia L. McIntosh, Thomas D. Madden and Marcel B. Bally
Journal of Pharmacology and Experimental Therapeutics January 2000, 292 (1) 337-345;

Article Information

vol. 292 no. 1 337-345
PubMed 
10604968
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received July 9, 1999
  • Accepted October 8, 1999
  • Published online January 1, 2000.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Howard J. Lim2,3,
  2. Dana Masin3,
  3. Natashia L. McIntosh3,
  4. Thomas D. Madden1 and
  5. Marcel B. Bally2,3
  1. Departments of 1Pharmacology and Therapeutics (T.D.M.) and 2Pathology and Laboratory Medicine (H.J.L., M.B.B.), University of British Columbia; and 3Department of Advanced Therapeutics, British Columbia Cancer Agency (H.J.L., D.M., N.L.M., M.B.B.), Vancouver, British Columbia, Canada
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    Research ArticleABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

    Role of Drug Release and Liposome-Mediated Drug Delivery in Governing the Therapeutic Activity of Liposomal Mitoxantrone Used to Treat Human A431 and LS180 Solid Tumors

    Howard J. Lim, Dana Masin, Natashia L. McIntosh, Thomas D. Madden and Marcel B. Bally
    Journal of Pharmacology and Experimental Therapeutics January 1, 2000, 292 (1) 337-345;
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