Table of Contents

Articles

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  Regulation of Opioid Receptor Activities

  Ping-Yee Law and Horace H. Loh

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 607-624;
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  Insulinotropic Effect of New Glibenclamide Isosteres

  R. Ouedraogo, Q.-A. Nguyen, M.-H. Antoine, C. Kane, M.J. Dunne, L. Pochet, B. Masereel and P. Lebrun

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 625-631;
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  Differential Induction of Nitric Oxide Synthase in Rat Gastric and Vascular Smooth Muscle Tissue: Distinct Tissue Distribution and Distinctive Signaling Pathways

  Xi-Long Zheng, Yu Gui, Keith A. Sharkey and Morley D. Hollenberg

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 632-640;
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  Cytochrome P-450-Dependent Bioactivation of 1,1-Dichloroethylene to a Reactive Epoxide in Human Lung and Liver Microsomes

  Taylor F. Dowsley, Ken Reid, Dimitri Petsikas, Judith B. Ulreich, Robyn L. Fisher and Poh-Gek Forkert

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 641-648;
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  Interleukin-2 Overexpresses c-myc and Down-Regulates Cytochrome P-450 in Rat Hepatocytes

  Marina Tinel, Johny Elkahwaji, Marie Anne Robin, Nicolas Fardel, Veronique Descatoire, Delphine Haouzi, Alain Berson and Dominique Pessayre

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 649-655;
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  Dependence of Nicotinic Acetylcholine Receptor Recovery from Desensitization on the Duration of Agonist Exposure

  Raven Reitstetter, Ronald J. Lukas and Raphael Gruener

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 656-660;
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  Competition Between Cytochrome P-450 Isozymes for NADPH-Cytochrome P-450 Oxidoreductase Affects Drug Metabolism

  Dongtao N. Li, Michael P. Pritchard, Steven P. Hanlon, Brian Burchell, C. Roland Wolf and Thomas Friedberg

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 661-667;
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  Combination of Hypoxia/Aglycemia Compromises In Vitro Blood-Brain Barrier Integrity

  Thomas J. Abbruscato and Thomas P. Davis

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 668-675;
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  Hydrolytic Activity Is Essential for Aceclofenac To Inhibit Cyclooxygenase in Rheumatoid Synovial Cells

  Ryuta Yamazaki, Shinichi Kawai, Tsuneo Matsumoto, Takeshi Matsuzaki, Shusuke Hashimoto, Teruo Yokokura, Renzo Okamoto, Tomihisa Koshino and Yutaka Mizushima

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 676-681;
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  Characterization of Vagal Afferent Subtypes Stimulated by Bradykinin in Guinea Pig Trachea

  Radhika Kajekar, David Proud, Allen C. Myers, Sonya N. Meeker and Bradley J. Undem

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 682-687;
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  Clonidine Evokes Vasodepressor Responses via α₂-Adrenergic Receptors in Gigantocellular Reticular Formation

  Sue A. Aicher and Carrie T. Drake

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 688-694;
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  Inhibition of Isoniazid-Induced Hepatotoxicity in Rabbits by Pretreatment with an Amidase Inhibitor ,

  Troy C. Sarich, Stephen P. Adams, Giorgio Petricca and James M. Wright

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 695-702;
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  Anticonvulsant Efficacy ofN-Methyl-d-Aspartate Antagonists Against Convulsions Induced by Cocaine

  Jeffrey M. Witkin, Maciej Gasior, Boris Heifets and Frank C. Tortella

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 703-711;
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  Cardiopulmonary Effects of the α₂-Adrenoceptor Agonists Medetomidine and ST-91 in Anesthetized Sheep

  C. S. Celly, W. N. McDonell and W. D. Black

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 712-720;
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  The Phospholipase C Inhibitor U73122 Inhibits Phorbol Ester-Induced Platelet Activation

  Leslie K. Lockhart and Archibald McNicol

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 721-728;
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  Inhibition of Gastric Emptying by Triterpene Saponin, Momordin Ic, in Mice: Roles of Blood Glucose, Capsaicin-Sensitive Sensory Nerves, and Central Nervous System

  H. Matsuda, Y. Li, J. Yamahara and M. Yoshikawa

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 729-734;
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  Effects of Specific Inhibition of Cyclooxygenase-2 on Sodium Balance, Hemodynamics, and Vasoactive Eicosanoids

  Francesca Catella-Lawson, Brendan McAdam, Briggs W. Morrison, Shiv Kapoor, Dean Kujubu, Lisa Antes, Kenneth C. Lasseter, Hui Quan, Barry J. Gertz and Garret A. Fitzgerald

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 735-741;
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  SR146131: A New Potent, Orally Active, and Selective Nonpeptide Cholecystokinin Subtype 1 Receptor Agonist. I: In Vitro Studies

  Eric Bignon, André Bachy, Robert Boigegrain, Roger Brodin, Michèle Cottineau, Danielle Gully, Jean-Marc Herbert, Peter Keane, Christophe Labie, Jean-Charles Molimard, Dominique Olliero, Florence Oury-Donat, Christophe Petereau, Valérie Prabonnaud, Marie-Pierre Rockstroh, Paul Schaeffer, Orlane Servant, Olivier Thurneyssen, Philippe Soubrié, Marc Pascal, Jean-Pierre Maffrand and Gérard Le Fur

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 742-751;
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  SR146131: A New Potent, Orally Active, and Selective Nonpeptide Cholecystokinin Subtype 1 Receptor Agonist. II: In Vivo Pharmacological Characterization

  Eric Bignon, Richard Alonso, Michèle Arnone, Robert Boigegrain, Roger Brodin, Christiane Gueudet, Michel Héaulme, Peter Keane, Marco Landi, Jean-Charles Molimard, Dominique Olliero, Martine Poncelet, Eric Seban, Jacques Simiand, Philippe Soubrié, Marc Pascal, Jean-Pierre Maffrand and Gérard Le Fur

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 752-761;
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  Mechanisms of Endothelin-Induced Venoconstriction in Isolated Guinea Pig Mesentery

  Ron J. Johnson, Gregory D. Fink and James J. Galligan

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 762-767;
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  Novel Membrane Transporter OCTN1 Mediates Multispecific, Bidirectional, and pH-Dependent Transport of Organic Cations

  Hikaru Yabuuchi, Ikumi Tamai, Jun-Ichi Nezu, Kazuki Sakamoto, Asuka Oku, Miyuki Shimane, Yoshimichi Sai and Akira Tsuji

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 768-773;
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  Effects of Ethanol on Recombinant Human Neuronal Nicotinic Acetylcholine Receptors Expressed in XenopusOocytes

  Rita A. Cardoso, Susan J. Brozowski, Laura E. Chavez-Noriega, Michael Harpold, C. Fernando Valenzuela and R. Adron Harris

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 774-780;
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  Proteasome Inhibition Leads to Significant Reduction of Bcr-Abl Expression and Subsequent Induction of Apoptosis in K562 Human Chronic Myelogenous Leukemia Cells

  Q. Ping Dou, Terence F. McGuire, Yibing Peng and Bing An

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 781-790;
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  Effects of Luteinizing Hormone-Releasing Hormone on Plasma Cocaine Levels in Rhesus Monkeys

  Jack H. Mendelson, Nancy K. Mello and S. Stevens Negus

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 791-799;
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  Evaluation of Individual and Combined Neurotoxicity of the Immunosuppressants Cyclosporine and Sirolimus by In Vitro Multinuclear NMR Spectroscopy

  Natalie Serkova, Lawrence Litt, Thomas L. James, Wolfgang Sadée, Dieter Leibfritz, Leslie Z. Benet and Uwe Christians

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 800-806;
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  Liposomal Lipid and Plasmid DNA Delivery to B16/BL6 Tumors after Intraperitoneal Administration of Cationic Liposome DNA Aggregates

  Dorothy L. Reimer, Spencer Kong, Myrna Monck, Jessica Wyles, Pat Tam, Ellen K. Wasan and Marcel B. Bally

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 807-815;
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  Size of Lipid Microdroplets Effects Results of Hepatic Arterial Chemotherapy with an Anticancer Agent in Water-in-Oil-in-Water Emulsion to Hepatocellular Carcinoma

  Shushi Higashi, Naoto Tabata, Kazu-Hiro Kondo, Yorio Maeda, Masataka Shimizu, Tadao Nakashima and Toshiaki Setoguchi

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 816-819;
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  Inhibition and Stimulation of Long-Chain Fatty Acid Oxidation by Chloroacetaldehyde and Methylene Blue in Rats

  Theresa M. Visarius, Jörg W. Stucki and Bernhard H. Lauterburg

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 820-824;
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  Differences in Cadmium Transport to the Testis, Epididymis, and Brain in Cadmium-Sensitive and -Resistant Murine Strains 129/J and A/J

  Laura M. King, William A. Banks and William J. George

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 825-830;
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  Temporal Differences in Actions of Calcium Channel Blockers on K⁺ Accumulation, Cardiac Function, and High-Energy Phosphate Levels in Ischemic Guinea Pig Hearts

  Ryuichi Sato, Jun Yamazaki and Taku Nagao

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 831-839;
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  Spinal Blockade of Opioid Receptors Prevents the Analgesia Produced by TENS in Arthritic Rats

  Kathleen A. Sluka, Merek Deacon, Andrea Stibal, Shannon Strissel and Amy Terpstra

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 840-846;
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  Post-Translational Inhibition of Cytochrome P-450 2E1 Expression by Chlomethiazole in Fao Hepatoma Cells

  Anastasia Simi and Magnus Ingelman-Sundberg

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 847-852;
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  Inhibition of Human Liver Cytochrome P-450 1A2 by the Class IB Antiarrhythmics Mexiletine, Lidocaine, and Tocainide

  Xiaoxiong Wei, Renke Dai, Suoping Zhai, Kenneth E. Thummel, Fred K. Friedman and Robert E. Vestal

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 853-858;
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  Enhancement of μ Opioid Antinociception by Oral Δ⁹-Tetrahydrocannabinol: Dose-Response Analysis and Receptor Identification

  Diana L. Cichewicz, Zachary L. Martin, Forrest L. Smith and Sandra P. Welch

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 859-867;
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  Periaqueductal Gray Stimulation-Induced Inhibition of Nociceptive Dorsal Horn Neurons in Rats Is Associated with the Release of Norepinephrine, Serotonin, and Amino Acids

  M. Cui, Y. Feng, D. J. McAdoo and W. D. Willis

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 868-876;
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  Characteristics of Drug Interactions with Recombinant Biogenic Amine Transporters Expressed in the Same Cell Type

  Amy J. Eshleman, Marya Carmolli, Medhane Cumbay, Carey R. Martens, Kim A. Neve and Aaron Janowsky

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 877-885;
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  Subtype-Selective Antagonism ofN-Methyl-d-Aspartate Receptors by Felbamate: Insights into the Mechanism of Action

  Nancy W. Kleckner, Jill C. Glazewski, Chi Chiung Chen and Tammy D. Moscrip

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 886-894;
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  Glyceryl Trinitrate-Induced Vasodilation Is Inhibited by Ultraviolet Irradiation Despite Enhanced Nitric Oxide Generation: Evidence for Formation of a Nitric Oxide Conjugate

  Aman S. Hussain, Natascha H. Crispino, Brian E. McLaughlin, James F. Brien, Gerald S. Marks and Kanji Nakatsu

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 895-900;
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  Osmotic Regulation of Airway Reactivity by Epithelium

  Jeffrey S. Fedan, Long-Xing Yuan, Victoria C. Chang, Joseph O. Viola, Deborah Cutler and Loreen L. Pettit

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 901-910;
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  Changes in Smooth Muscle Tone During Osmotic Challenge in Relation to Epithelial Bioelectric Events in Guinea Pig Isolated Trachea

  Juanita Dortch-Carnes, Michael R. van Scott and Jeffrey S. Fedan

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 911-917;
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  Adrenoceptors Mediating the Cardiovascular and Metabolic Effects of α-Methylnoradrenaline in Humans

  Rafael F. Schäfers, Jens Nürnberger, Burghard Herrmann, Rene R. Wenzel, Thomas Philipp and Martin C. Michel

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 918-925;
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  Receptor Binding, Behavioral, and Electrophysiological Profiles of Nonpeptide Corticotropin-Releasing Factor Subtype 1 Receptor Antagonists CRA1000 and CRA1001

  Shigeru Okuyama, Shigeyuki Chaki, Naoya Kawashima, Yoshiko Suzuki, Shin-Ichi Ogawa, Atsuro Nakazato, Toshihito Kumagai, Taketoshi Okubo and Kazuyuki Tomisawa

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 926-935;
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  Relative Potency of levo-α-Acetylmethadol and Methadone in Humans under Acute Dosing Conditions

  Thomas Eissenberg, Maxine L. Stitzer, George E. Bigelow, August R. Buchhalter and Sharon L. Walsh

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 936-945;
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  Determination of [³⁵S]Guanosine-5′-O-(3-thio)Triphosphate Binding Mediated by Cholinergic Muscarinic Receptors in Membranes from Chinese Hamster Ovary Cells and Rat Striatum Using an Anti-G Protein Scintillation Proximity Assay

  Neil W. Delapp, Jamie H. McKinzie, Barry D. Sawyer, Amy Vandergriff, Julie Falcone, Don McClure and Christian C. Felder

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 946-955;
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  Zinc Modulates Antagonist Interactions with D₂-Like Dopamine Receptors through Distinct Molecular Mechanisms

  John A. Schetz, Alice Chu and David R. Sibley

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 956-964;
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  Sensitivity to the Discriminative Stimulus and Antinociceptive Effects of μ Opioids: Role of Strain of Rat, Stimulus Intensity, and Intrinsic Efficacy at the μ Opioid Receptor

  Drake Morgan, Charles D. Cook and Mitchell J. Picker

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 965-975;
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  Clearance of Human Brain Natriuretic Peptide in Rabbits; Effect of the Kidney, the Natriuretic Peptide Clearance Receptor, and Peptidase Activity

  Ramona Almirez and Andrew A. Protter

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 976-980;
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  A Simple Method for Estimation of Agonist Activity at Receptor Subtypes: Comparison of Native and Cloned M₃ Muscarinic Receptors in Guinea Pig Ileum and Transfected Cells

  Frederick J. Ehlert, Michael T. Griffin, Gregory W. Sawyer and Regina Bailon

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 981-992;
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  Interaction Between Medullary and Spinal δ₁ and δ₂ Opioid Receptors in the Production of Antinociception in the Rat

  Robert W. Hurley, Theodore S. Grabow, Ronald J. Tallarida and Donna L. Hammond

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 993-999;
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  Clozapine, But Not Haloperidol, Prevents the Functional Hyperactivity of N-Methyl-d-Aspartate Receptors in Rat Cortical Neurons Induced by Subchronic Administration of Phencyclidine

  V. L. Arvanov and R. Y. Wang

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 1000-1006;
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  Secretory Leukocyte Protease Inhibitor Prevents Allergen-Induced Pulmonary Responses in Animal Models of Asthma

  Clifford D. Wright, Andrew M. Havill, Scot C. Middleton, Mohammed A. Kashem, Patrice A. Lee, David J. Dripps, Thomas G. O’Riordan, Michael P. Bevilacqua and William M. Abraham

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 1007-1014;
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  Cerebrospinal Fluid Bioavailability and Pharmacokinetics of Bupivacaine and Lidocaine after Intrathecal and Epidural Administrations in Rabbits Using Microdialysis

  Rozenn Clement, Jean-Marc Malinovsky, Pascal Le Corre, Gilles Dollo, Francois Chevanne and Roger Le Verge

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 1015-1021;
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  A Tyrosine Kinase Signaling Pathway, Regulated by Calcium Entry and Dissociated from Tyrosine Phosphorylation of Phospholipase Cγ-1, Is Involved in Inositol Phosphate Production by Activated G Protein-Coupled Receptors in Myometrium

  Bruno Palmier, Monique Vacher, Simone Harbon and Denis Leiber

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 1022-1030;
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  Characterization of Neuropeptide Y-Induced Feeding in Mice: Do Y1–Y6 Receptor Subtypes Mediate Feeding?

  Smriti Iyengar, Dominic L. Li and Rosa Maria A. Simmons

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 1031-1040;
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  Characterization of the Effects of Polyamines on [¹²⁵I]MK-801 Binding to RecombinantN-Methyl-d-Aspartate Receptors

  Terre A. Sharma and Ian J. Reynolds

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 1041-1047;
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  d-Methadone Blocks Morphine Tolerance andN-Methyl-d-Aspartate-Induced Hyperalgesia

  Antonia M. Davis and Charles E. Inturrisi

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 1048-1053;
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  Role of Cytochrome P-450 2E1 in Methacrylonitrile Metabolism and Disposition

  Burhan I. Ghanayem, J. Michael Sanders, Brian Chanas, Leo T. Burka and Frank J. Gonzalez

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 1054-1059;
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  Prolonged Analgesic Effect of Ketamine, anN-Methyl-d-Aspartate Receptor Inhibitor, in Patients with Chronic Pain

  Toril Rabben, Per Skjelbred and Ivar Øye

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 1060-1066;
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  Characterization of the Pharmacodynamic Interaction between Parent Drug and Active Metabolite In Vivo: Midazolam and α-OH-Midazolam

  B. Tuk, M. F. van Oostenbruggen, V. M. M. Herben, J. W. Mandema and M. Danhof

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 1067-1074;
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  Structural Analysis of Angiotensin IV Receptor (AT₄) from Selected Bovine Tissues

  Jian-Hua Zhang, Jodie M. Hanesworth, Michael F. Sardinia, Jeremiah A. Alt, John W. Wright and Joseph W. Harding

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 1075-1083;
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  Active Transport of Fentanyl by the Blood-Brain Barrier

  Thomas K. Henthorn, Yang Liu, Mrinal Mahapatro and Ka-yun Ng

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 1084-1089;
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  Two Pharmacologically Distinct Components of Nicotinic Receptor-Mediated Rubidium Efflux in Mouse Brain Require the β2 Subunit

  Michael J. Marks, Paul Whiteaker, Jennifer Calcaterra, Jerry A. Stitzel, Amy E. Bullock, Sharon R. Grady, Marina R. Picciotto, Jean-Pierre Changeux and Allan C. Collins

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 1090-1103;
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  Active Lucifer Yellow Secretion in Renal Proximal Tubule: Evidence for Organic Anion Transport System Crossover

  Rosalinde Masereeuw, Miek M. Moons, Barbara H. Toomey, Frans G. M. Russel and David S. Miller

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 1104-1111;
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  Stimulation of Pregnant Rat Uterine Contraction by the Polychlorinated Biphenyl (PCB) Mixture Aroclor 1242 May Be Mediated by Arachidonic Acid Release through Activation of Phospholipase A₂ Enzymes

  Jeehyeon Bae, Marc Peters-Golden and Rita Loch-Caruso

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 1112-1120;
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  Insulin Differentially Affects Xenobiotic-Enhanced, Cytochrome P-450 (CYP)2E1, CYP2B, CYP3A, and CYP4A Expression in Primary Cultured Rat Hepatocytes

  Kimberley J. Woodcroft and Raymond F. Novak

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 1121-1127;
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  Reduction of the Cardiotoxicity of Doxorubicin in Rabbits and Dogs by Encapsulation in Long-Circulating, Pegylated Liposomes

  Peter K. Working, Mary S. Newman, Timothy Sullivan and John Yarrington

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 1128-1133;
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  First-Pass Midazolam Metabolism Catalyzed by 1α,25-Dihydroxy Vitamin D₃-Modified Caco-2 Cell Monolayers

  Jeannine M. Fisher, Steven A. Wrighton, Paul B. Watkins, Phyllissa Schmiedlin-Ren, Justina C. Calamia, Danny D. Shen, Kent L. Kunze and Kenneth E. Thummel

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 1134-1142;
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  Midazolam Metabolism by Modified Caco-2 Monolayers: Effects of Extracellular Protein Binding

  Jeannine M. Fisher, Steven A. Wrighton, Justina C. Calamia, Danny D. Shen, Kent L. Kunze and Kenneth E. Thummel

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 1143-1150;
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  Identification and Pharmacological Characterization of a Series of New 1H-4-Substituted-Imidazoyl Histamine H₃ Receptor Ligands

  Stephen L. Yates, James G. Phillips, Rosilyn Gregory, Gary P. Pawlowski, Leena Fadnis, M. Amin Khan, Syed M. Ali and Clark E. Tedford

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 1151-1159;
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  Development oftrans-2-[1H-Imidazol-4-yl] Cyclopropane Derivatives as New High-Affinity Histamine H₃ Receptor Ligands

  Clark E. Tedford, James G. Phillips, Rosilyn Gregory, Gary P. Pawlowski, Leena Fadnis, M. Amin Khan, Syed M. Ali, Michael K. Handley and Stephen L. Yates

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 1160-1168;
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  Glucuronidation of Drugs by Hepatic Microsomes Derived from Healthy and Cirrhotic Human Livers

  Valerie Furlan, Sylvie Demirdjian, Olivier Bourdon, Jacques Magdalou and Anne-Marie Taburet

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 1169-1175;
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  Targeted Delivery and Improved Therapeutic Potential of Catalase by Chemical Modification: Combination with Superoxide Dismutase Derivatives

  Yoshiyuki Yabe, Makiya Nishikawa, Ayumi Tamada, Yoshinobu Takakura and Mitsuru Hashida

  Journal of Pharmacology and Experimental Therapeutics May 1999, 289 (2) 1176-1184;