Table of Contents

Articles

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  Delta-Opioid Ligands Reverse Alfentanil-Induced Respiratory Depression but Not Antinociception

  Ying-Fu Su, Robert W. McNutt and Kwen-Jen Chang

  Journal of Pharmacology and Experimental Therapeutics December 1998, 287 (3) 815-823;
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  Inhibitory Action of Mibefradil on Calcium Signaling and Aldosterone Synthesis in Bovine Adrenal Glomerulosa Cells

  Michel F. Rossier, Eric A. Ertel, Michel B. Vallotton and Alessandro M. Capponi

  Journal of Pharmacology and Experimental Therapeutics December 1998, 287 (3) 824-831;
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  Role of Vasoactive Intestinal Polypeptide in the Adaptation of Intestinal Smooth Muscle Cells to Mechanical Distension

  Moez Rekik, Michel Delvaux, Jacques Frexinos and Lionel Bueno

  Journal of Pharmacology and Experimental Therapeutics December 1998, 287 (3) 832-838;
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  Effects of 5-Hydroxytryptamine₂ Receptor Antagonism on the Behavioral Activation and Immediate Early Gene Expression Induced by Dizocilpine

  Michael F. O’Neill, Caroline A. Hicks, Gillian Shaw, Tirumaran Parameswaran, Geraldine P. Cardwell and Michael J. O’Neill

  Journal of Pharmacology and Experimental Therapeutics December 1998, 287 (3) 839-846;
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  Differences Between the Antinociceptive Effects of the Cholinergic Channel Activators A-85380 and (±)-Epibatidine in Rats

  Peter Curzon, Arthur L. Nikkel, Anthony W. Bannon, Stephen P. Arneric and Michael W. Decker

  Journal of Pharmacology and Experimental Therapeutics December 1998, 287 (3) 847-853;
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  Antitumor Necrosis Factor Therapy in Rat Chronic Granulomatous Colitis: Critical Dose-Timing Effects on Outcome

  Sebastián Videla, Ana García-Lafuente, María Antolín, Jaime Vilaseca, Francisco Guarner, Ernesto Crespo, Guadalupe González, Antonio Salas and Juan R. Malagelada

  Journal of Pharmacology and Experimental Therapeutics December 1998, 287 (3) 854-859;
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  OPC-41061, a Highly Potent Human Vasopressin V₂-Receptor Antagonist: Pharmacological Profile and Aquaretic Effect by Single and Multiple Oral Dosing in Rats

  Yoshitaka Yamamura, Shigeki Nakamura, Shuji Itoh, Takahiro Hirano, Toshiyuki Onogawa, Tatsuya Yamashita, Yoshihisa Yamada, Kenji Tsujimae, Masashi Aoyama, Kounori Kotosai, Hidenori Ogawa, Hiroshi Yamashita, Kazumi Kondo, Michiaki Tominaga, Gozoh Tsujimoto and Toyoki Mori

  Journal of Pharmacology and Experimental Therapeutics December 1998, 287 (3) 860-867;
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  Role of Lipid Peroxidation in Dapsone-Induced Hemolytic Anemia

  David C. McMillan, Charles B. Jensen and David J. Jollow

  Journal of Pharmacology and Experimental Therapeutics December 1998, 287 (3) 868-876;
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  The Antiestrogen Tamoxifen Blocks the Delayed Rectifier Potassium Current, I_Kr, in Rabbit Ventricular Myocytes

  Xiao-Ke Liu, Alexander Katchman, Steven N. Ebert and Raymond L. Woosley

  Journal of Pharmacology and Experimental Therapeutics December 1998, 287 (3) 877-883;
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  Dual Activation and Inhibition of Adenylyl Cyclase by Cannabinoid Receptor Agonists: Evidence for Agonist-Specific Trafficking of Intracellular Responses

  D. W. Bonhaus, L. K. Chang, J. Kwan and G. R. Martin

  Journal of Pharmacology and Experimental Therapeutics December 1998, 287 (3) 884-888;
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  Pardaxin, a New Pharmacological Tool to Stimulate the Arachidonic Acid Cascade in PC12 Cells

  Saleh Abu-Raya, Eugenia Bloch-Shilderman, Esther Shohami, Victoria Trembovler, Yechiel Shai, Joseph Weidenfeld, Saul Yedgar, Yehuda Gutman and Philip Lazarovici

  Journal of Pharmacology and Experimental Therapeutics December 1998, 287 (3) 889-896;
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  Polyol Pathway Hyperactivity Is Closely Related to Carnitine Deficiency in the Pathogenesis of Diabetic Neuropathy of Streptozotocin-Diabetic Rats

  Jiro Nakamura, Naoki Koh, Fumihiko Sakakibara, Yoji Hamada, Tomohiro Hara, Hiromitsu Sasaki, Sadao Chaya, Taku Komori, Eitaro Nakashima, Keiko Naruse, Koichi Kato, Naohide Takeuchi, Yasuhide Kasuya and Nigishi Hotta

  Journal of Pharmacology and Experimental Therapeutics December 1998, 287 (3) 897-902;
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  Hypoxia Stimulates the Synthesis of Cytochrome P450-Derived Inflammatory Eicosanoids in Rabbit Corneal Epithelium

  Christina Vafeas, Paul A. Mieyal, Ferdinando Urbano, John R. Falck, Kamlesh Chauhan, Michael Berman and Michal Laniado Schwartzman

  Journal of Pharmacology and Experimental Therapeutics December 1998, 287 (3) 903-910;
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  Effects of P-glycoprotein Modulators on Etoposide Elimination and Central Nervous System Distribution

  David E. Burgio, Michael P. Gosl and and Patrick J. McNamara

  Journal of Pharmacology and Experimental Therapeutics December 1998, 287 (3) 911-917;
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  Analysis of 3-(4-Hydroxy, 2-Methoxybenzylidene)Anabaseine Selectivity and Activity at Human and Rat Alpha-7 Nicotinic Receptors

  Edwin M. Meyer, Alexander Kuryatov, Volodymyr Gerzanich, Jon Lindstrom and Roger L. Papke

  Journal of Pharmacology and Experimental Therapeutics December 1998, 287 (3) 918-925;
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  Evidence for an Endogenous cAMP-Adenosine Pathway in the Rat Kidney

  Zaichuan Mi and Edwin K. Jackson

  Journal of Pharmacology and Experimental Therapeutics December 1998, 287 (3) 926-930;
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  Aldosterone Receptor Blockade Inhibits Increased Furosemide-Sensitive Sodium Reabsorption in Rats with Liver Cirrhosis

  Thomas E. N. Jonassen, Jørgen Søberg Petersen, Anne-Mette Sørensen, Frederik Andreasen and Sten Christensen

  Journal of Pharmacology and Experimental Therapeutics December 1998, 287 (3) 931-936;
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  Spinal Morphine/Clonidine Antinociceptive Synergism is Regulated by Protein Kinase C, but not Protein Kinase A Activity

  Zhong You Wei and Sandra C. Roerig

  Journal of Pharmacology and Experimental Therapeutics December 1998, 287 (3) 937-943;
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  Substrate Specificity of Organic Cation/H⁺ Exchange in Avian Renal Brush-Border Membranes

  A. R. Villalobos and E. J. Braun

  Journal of Pharmacology and Experimental Therapeutics December 1998, 287 (3) 944-951;
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  The Role of Histamine H₁, H₂ and H₃ Receptors on Enteric Ascending Synaptic Transmission in the Guinea Pig Ileum

  Angelo A. Izzo, Marcello Costa, Nicola Mascolo and Francesco Capasso

  Journal of Pharmacology and Experimental Therapeutics December 1998, 287 (3) 952-957;
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  Suppression of Nicotine Intake During Ad LibitumCigarette Smoking by High-Dose Transdermal Nicotine

  Neal L. Benowitz, Shoshana Zevin and Peyton Jacob

  Journal of Pharmacology and Experimental Therapeutics December 1998, 287 (3) 958-962;
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  Modulation of the Tumor Disposition of Vinca Alkaloids by PSC 833In Vitro and In Vivo

  Saeheum Song, Hiroshi Suzuki, Tetsuya Terasaki, Michel Lemaire and Yuichi Sugiyama

  Journal of Pharmacology and Experimental Therapeutics December 1998, 287 (3) 963-968;
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  Differential Contribution of R and SIsomers in Ketoprofen Anti-inflammatory Activity: Role of Cytokine Modulation

  Pietro Ghezzi, Gabriella Melillo, Cristina Meazza, Silvano Sacco, Luigi Pellegrini, Cinzia Asti, Stefano Porzio, Antonello Marullo, Vilma Sabbatini, Gianfranco Caselli and Riccardo Bertini

  Journal of Pharmacology and Experimental Therapeutics December 1998, 287 (3) 969-974;
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  The Role of CYP2C in the In Vitro Bioactivation of the Contraceptive Steroid Desogestrel

  Daniela M. Gentile, Carole H. J. Verhoeven, Tsutomu Shimada and David J. Back

  Journal of Pharmacology and Experimental Therapeutics December 1998, 287 (3) 975-982;
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  Effects of Pramipexole on Contraversive Rotation and Functional Motor Impairments in 1-Methyl-4-phenyl1,2,3,6-tetrahydropyridine-Induced Chronic Hemiparkinsonian Monkeys

  Edward F. Domino, Lisong Ni, Huilei Zhang, Yasuko Kohno and Masashi Sasa

  Journal of Pharmacology and Experimental Therapeutics December 1998, 287 (3) 983-987;
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  Antiasthmatic Activity of the Second-Generation Phosphodiesterase 4 (PDE4) Inhibitor SB 207499 (Ariflo) in the Guinea Pig

  David C. Underwood, Steven Bochnowicz, Ruth R. Osborn, Charles J. Kotzer, Mark A. Luttmann, Douglas W.P. Hay, Peter D. Gorycki, Siegfried B. Christensen and Theodore J. Torphy

  Journal of Pharmacology and Experimental Therapeutics December 1998, 287 (3) 988-995;
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  KN-93, an Inhibitor of Multifunctional Ca⁺⁺/Calmodulin-Dependent Protein Kinase, Decreases Early Afterdepolarizations in Rabbit Heart

  Mark E. Anderson, Andrew P. Braun, Yuejin Wu, Tong Lu, Yiming Wu, Howard Schulman and Ruey J. Sung

  Journal of Pharmacology and Experimental Therapeutics December 1998, 287 (3) 996-1006;
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  Modulatory Effect of Environmental Stimuli on the Susceptibility to Amphetamine Sensitization: A Dose-Effect Study in Rats

  Kaitlin E. Browman, Aldo Badiani and Terry E. Robinson

  Journal of Pharmacology and Experimental Therapeutics December 1998, 287 (3) 1007-1014;
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  Magnesium-Dependent Inhibition of N-Methyl-d-Aspartate Receptor-Mediated Synaptic Transmission by Ethanol

  Jeffrey L. Calton, Wilkie A. Wilson and Scott D. Moore

  Journal of Pharmacology and Experimental Therapeutics December 1998, 287 (3) 1015-1019;
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  Persistently Exaggerated Startle Responses in Rats Treated with Pyridostigmine Bromide

  Richard J. Servatius, John E. Ottenweller, Dawn Beldowicz, Weidun Guo, Guanping Zhu and Benjamin H. Natelson

  Journal of Pharmacology and Experimental Therapeutics December 1998, 287 (3) 1020-1028;
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  Chronic l-Alpha Acetylmethadol in Rhesus Monkeys: Discriminative Stimulus and Other Behavioral Measures of Dependence and Withdrawal

  Michael R. Brandt and Charles P. France

  Journal of Pharmacology and Experimental Therapeutics December 1998, 287 (3) 1029-1037;
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  Modulation of CB1 Cannabinoid Receptor Functions after a Long-Term Exposure to Agonist or Inverse Agonist in the Chinese Hamster Ovary Cell Expression System

  Murielle Rinaldi-Carmona, Anne Le Duigou, Didier Oustric, Francis Barth, Monsif Bouaboula, Pierre Carayon, Pierre Casellas and Gérard Le Fur

  Journal of Pharmacology and Experimental Therapeutics December 1998, 287 (3) 1038-1047;
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  Mercaptoethylguanidine, a Combined Inhibitor of Nitric Oxide Synthase and Peroxynitrite Scavenger, Reduces Trinitrobenzene Sulfonic Acid-Induced Colonic Damage in Rats

  Basilia Zingarelli, Salvatore Cuzzocrea, Csaba Szabó and Andrew L. Salzman

  Journal of Pharmacology and Experimental Therapeutics December 1998, 287 (3) 1048-1055;
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  Cellular Mechanisms of Renal Adaptation of Sodium Dependent Sulfate Cotransport to Altered Dietary Sulfate in Rats

  Kazuko Sagawa, Debra C. DuBois, Richard R. Almon, Heini Murer and Marilyn E. Morris

  Journal of Pharmacology and Experimental Therapeutics December 1998, 287 (3) 1056-1062;
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  HMN-1180, a Small Molecule Inhibitor of Neuronal Nitric Oxide Synthase

  Masahiro Nishio, Yasuo Watanabe and Hiroyoshi Hidaka

  Journal of Pharmacology and Experimental Therapeutics December 1998, 287 (3) 1063-1067;
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  Peripheral Effects of Opioids in a Model of Chronic Intestinal Inflammation in Mice ,

  Margarita M. Puig and Olga Pol

  Journal of Pharmacology and Experimental Therapeutics December 1998, 287 (3) 1068-1075;
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  Differential Effects of N-Methyl-d-Aspartate Receptor Blockade on Eticlopride-Induced Immediate Early Gene Expression in the Medial and Lateral Striatum

  Kristen A. Keefe and Amy C. Adams

  Journal of Pharmacology and Experimental Therapeutics December 1998, 287 (3) 1076-1083;
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  Protective Effect of FK409, a Spontaneous Nitric Oxide Releaser, on Ischemic Acute Renal Failure in Rats

  Yasuo Matsumura, Manabu Nishiura, Shougo Deguchi, Norio Hashimoto, Toshikazu Ogawa and Rumi Seo

  Journal of Pharmacology and Experimental Therapeutics December 1998, 287 (3) 1084-1091;
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  Ibuprofen-Induced Changes in Sulfate Renal Transport

  Kazuko Sagawa, Lisa Jo Benincosa, Heini Murer and Marilyn E. Morris

  Journal of Pharmacology and Experimental Therapeutics December 1998, 287 (3) 1092-1097;
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  Ebselen Protects Mice Against T Cell-Dependent, TNF-Mediated Apoptotic Liver Injury¹

  Gisa Tiegs, Sabine Küsters, Gerald Künstle, Hannes Hentze, Alexandra K. Kiemer and Albrecht Wendel

  Journal of Pharmacology and Experimental Therapeutics December 1998, 287 (3) 1098-1104;
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  Transforming Growth Factor-Beta 1 (TGF-β1) Promotes IL-2 mRNA Expression Through the Up-regulation of NF-κB, AP-1 and NF-AT in EL4 Cells

  Seung H. Han, Sung Su Yea, Young J. Jeon, Kyu-H. Yang and Norbert E. Kaminski

  Journal of Pharmacology and Experimental Therapeutics December 1998, 287 (3) 1105-1112;
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  Lipopolysaccharide Activation of Murine Splenocytes and Splenic B Cells Increased the Expression of Aryl Hydrocarbon Receptor and Aryl Hydrocarbon Receptor Nuclear Translocator

  Rebecca S. Marcus, Michael P. Holsapple and Norbert E. Kaminski

  Journal of Pharmacology and Experimental Therapeutics December 1998, 287 (3) 1113-1118;
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  Multiple Subtypes of Serotonin Receptors Are Expressed in Rat Sensory Neurons in Culture

  Joanne J. Chen, Michael R. Vasko, Xiaoping Wu, Theodora P. Staeva, Melvyn Baez, John M. Zgombick and David L. Nelson

  Journal of Pharmacology and Experimental Therapeutics December 1998, 287 (3) 1119-1127;
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  Investigation of the Tobacco-Specific Carcinogen 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone for In Vivoand In Vitro Murine Embryopathy and Embryonic rasMutations

  Louise M. Winn, Perry M. Kim and Peter G. Wells

  Journal of Pharmacology and Experimental Therapeutics December 1998, 287 (3) 1128-1135;
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  Nicotine Evokes Cell Death in Embryonic Rat Brain during Neurulation

  T. S. Roy, J. E. Andrews, F. J. Seidler and T. A. Slotkin

  Journal of Pharmacology and Experimental Therapeutics December 1998, 287 (3) 1136-1144;