Blockade of HERG and Kv1.5 by Ketoconazole

Robert Dumaine; Mary-Louise Roy; Arthur M. Brown

Article Information

vol. 286 no. 2 727-735

PubMed

9694927

Published By

American Society for Pharmacology and Experimental Therapeutics

Print ISSN

0022-3565

Online ISSN

1521-0103

History

Received December 15, 1997
Accepted April 28, 1998
Published online August 1, 1998.

The American Society for Pharmacology and Experimental Therapeutics

Author Information

Robert Dumaine,
Mary-Louise Roy and
Arthur M. Brown

Rammelkamp Center for Research, MetroHealth Medical Center, Case Western Reserve University School of Medicine, Cleveland Ohio

View Full Text

Statistics from Altmetric.com

Article usage

Article usage: January 1999 to February 2023

	Abstract	Full	Pdf
Jan 1999	1	9	6
Feb 1999	0	3	3
Mar 1999	3	8	5
Apr 1999	2	4	4
May 1999	3	9	1
Jun 1999	4	3	5
Jul 1999	0	1	0
Aug 1999	0	10	17
Sep 1999	2	8	11
Oct 1999	0	2	2
Nov 1999	0	5	7
Dec 1999	1	4	2
Jan 2000	1	5	7
Feb 2000	2	15	11
Mar 2000	0	13	8
Apr 2000	0	5	7
May 2000	2	3	11
Jun 2000	1	15	9
Jul 2000	1	12	12
Aug 2000	3	17	13
Sep 2000	1	5	15
Oct 2000	1	16	15
Nov 2000	0	9	7
Dec 2000	0	7	9
Jan 2001	2	15	12
Feb 2001	1	16	10
Mar 2001	1	17	18
Apr 2001	0	8	10
May 2001	3	6	7
Jun 2001	1	7	9
Jul 2001	3	7	15
Aug 2001	2	8	16
Sep 2001	1	5	5
Oct 2001	2	18	18
Nov 2001	0	17	19
Dec 2001	0	9	9
Jan 2002	2	11	6
Feb 2002	0	10	7
Mar 2002	1	17	10
Apr 2002	0	9	6
May 2002	7	7	17
Jun 2002	1	11	9
Jul 2002	1	14	14
Aug 2002	1	9	17
Sep 2002	1	11	7
Oct 2002	1	13	11
Nov 2002	0	16	16
Dec 2002	2	10	13
Jan 2003	1	11	7
Feb 2003	0	16	12
Mar 2003	1	8	8
Apr 2003	1	17	21
May 2003	1	2	4
Jun 2003	2	6	9
Jul 2003	8	24	13
Aug 2003	9	16	11
Sep 2003	10	22	31
Oct 2003	10	21	13
Nov 2003	17	42	13
Dec 2003	12	40	7
Jan 2004	18	46	22
Feb 2004	13	29	25
Mar 2004	11	49	16
Apr 2004	19	48	18
May 2004	17	41	8
Jun 2004	10	42	11
Jul 2004	24	45	12
Aug 2004	18	39	16
Sep 2004	14	42	19
Oct 2004	13	44	9
Nov 2004	8	41	22
Dec 2004	7	35	8
Jan 2005	15	39	12
Feb 2005	13	38	16
Mar 2005	10	41	13
Apr 2005	4	30	5
May 2005	14	31	14
Jun 2005	9	28	13
Jul 2005	13	25	14
Aug 2005	7	24	12
Sep 2005	12	16	13
Oct 2005	9	69	14
Nov 2005	16	32	15
Dec 2005	6	17	5
Jan 2006	6	22	4
Feb 2006	10	17	7
Mar 2006	10	41	12
Apr 2006	1	16	6
May 2006	2	14	7
Jun 2006	7	21	9
Jul 2006	5	34	6
Aug 2006	7	22	4
Sep 2006	6	13	9
Oct 2006	5	14	7
Nov 2006	6	26	18
Dec 2006	5	15	7
Jan 2007	7	19	11
Feb 2007	8	27	12
Mar 2007	7	13	3
Apr 2007	8	24	15
May 2007	6	12	11
Jun 2007	2	12	4
Jul 2007	4	21	10
Aug 2007	2	18	4
Sep 2007	2	23	6
Oct 2007	11	33	12
Nov 2007	14	30	7
Dec 2007	3	19	7
Jan 2008	2	17	11
Feb 2008	5	10	12
Mar 2008	7	18	9
Apr 2008	8	22	15
May 2008	12	22	12
Jun 2008	12	22	13
Jul 2008	2	22	6
Aug 2008	13	6	4
Sep 2008	6	10	7
Oct 2008	9	10	4
Nov 2008	8	18	10
Dec 2008	12	7	6
Jan 2009	5	13	11
Feb 2009	4	12	9
Mar 2009	10	20	10
Apr 2009	2	9	6
May 2009	3	12	9
Jun 2009	5	16	8
Jul 2009	4	17	10
Aug 2009	3	9	7
Sep 2009	10	6	5
Oct 2009	10	12	9
Nov 2009	9	10	5
Dec 2009	7	13	3
Jan 2010	5	13	6
Feb 2010	9	10	9
Mar 2010	9	11	10
Apr 2010	8	14	8
May 2010	5	10	8
Jun 2010	9	18	7
Jul 2010	22	2	3
Aug 2010	2	12	6
Sep 2010	7	7	7
Oct 2010	2	11	7
Nov 2010	11	9	10
Dec 2010	3	4	3
Jan 2011	10	18	10
Feb 2011	13	9	7
Mar 2011	3	17	6
Apr 2011	7	17	12
May 2011	9	11	13
Jun 2011	4	2	7
Jul 2011	8	9	5
Aug 2011	6	5	9
Sep 2011	5	8	9
Oct 2011	6	11	9
Nov 2011	8	4	8
Dec 2011	4	6	4
Jan 2012	6	11	22
Feb 2012	1	8	18
Mar 2012	17	11	5
Apr 2012	3	10	6
May 2012	3	6	5
Jun 2012	5	12	9
Jul 2012	5	10	5
Aug 2012	11	8	9
Sep 2012	8	10	8
Oct 2012	6	14	9
Nov 2012	5	7	12
Dec 2012	4	7	7
Jan 2013	13	12	9
Feb 2013	5	14	9
Mar 2013	4	8	6
Apr 2013	3	8	16
May 2013	6	9	23
Jun 2013	1	1	2
Jul 2013	4	4	5
Aug 2013	1	3	2
Sep 2013	3	1	1
Oct 2013	4	3	1
Nov 2013	5	6	4
Dec 2013	1	3	0
Jan 2014	0	5	11
Feb 2014	3	2	4
Mar 2014	3	2	4
Apr 2014	3	5	5
May 2014	8	6	7
Jun 2014	1	10	6
Jul 2014	2	6	4
Aug 2014	4	5	21
Sep 2014	1	4	1
Oct 2014	4	4	0
Nov 2014	5	2	2
Dec 2014	0	4	8
Jan 2015	4	4	3
Feb 2015	2	8	2
Mar 2015	7	6	4
Apr 2015	0	7	7
May 2015	3	5	5
Jun 2015	2	4	4
Jul 2015	3	11	4
Aug 2015	0	8	3
Sep 2015	12	5	9
Oct 2015	4	4	3
Nov 2015	10	4	8
Dec 2015	13	1	0
Jan 2016	4	8	3
Feb 2016	9	8	6
Mar 2016	12	7	14
Apr 2016	9	3	14
May 2016	11	1	7
Jun 2016	3	0	6
Jul 2016	7	3	9
Aug 2016	12	2	14
Sep 2016	7	7	10
Oct 2016	4	7	4
Nov 2016	3	3	5
Dec 2016	1	7	5
Jan 2017	0	8	3
Feb 2017	0	6	2
Mar 2017	0	15	1
Apr 2017	0	9	0
May 2017	0	18	3
Jun 2017	0	5	0
Jul 2017	0	9	1
Aug 2017	0	6	5
Sep 2017	3	13	8
Oct 2017	0	9	7
Nov 2017	0	16	2
Dec 2017	1	9	4
Jan 2018	0	17	4
Feb 2018	0	5	4
Mar 2018	0	14	6
Apr 2018	1	7	2
May 2018	0	17	9
Jun 2018	0	9	6
Jul 2018	0	5	2
Aug 2018	0	4	5
Sep 2018	0	15	11
Oct 2018	0	6	6
Nov 2018	0	5	2
Dec 2018	12	0	3
Jan 2019	4	0	0
Feb 2019	14	2	3
Mar 2019	5	2	3
Apr 2019	4	0	1
May 2019	2	1	1
Jun 2019	9	1	5
Jul 2019	28	2	1
Aug 2019	26	2	4
Sep 2019	7	2	2
Oct 2019	11	2	1
Nov 2019	29	12	5
Dec 2019	10	15	1
Jan 2020	0	17	0
Feb 2020	8	7	1
Mar 2020	6	1	1
Apr 2020	8	1	1
May 2020	7	2	1
Jun 2020	0	1	1
Jul 2020	2	3	3
Aug 2020	2	0	1
Sep 2020	10	1	1
Oct 2020	12	2	0
Nov 2020	10	2	1
Dec 2020	10	1	0
Jan 2021	6	3	1
Feb 2021	23	4	1
Mar 2021	10	1	0
Apr 2021	17	3	1
May 2021	22	3	0
Jun 2021	5	6	1
Jul 2021	7	1	0
Aug 2021	7	4	0
Sep 2021	1	2	0
Oct 2021	10	1	0
Nov 2021	18	1	0
Dec 2021	4	0	0
Jan 2022	20	3	0
Feb 2022	4	3	1
Mar 2022	7	1	0
Apr 2022	8	5	0
May 2022	9	2	1
Jun 2022	18	2	0
Jul 2022	13	2	0
Aug 2022	12	1	0
Sep 2022	8	2	1
Oct 2022	13	2	0
Nov 2022	9	1	1
Dec 2022	24	1	0
Jan 2023	30	2	0
Feb 2023	1	0	0