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The Contribution of Classical (β1/2-) and Atypical β-Adrenoceptors to the Stimulation of Human White Adipocyte Lipolysis and Right Atrial Appendage Contraction by Novel β3-Adrenoceptor Agonists of Differing Selectivities

Matthew V. Sennitt, Alberto J. Kaumann, Peter Molenaar, Lee J. Beeley, Paul W. Young, John Kelly, Helen Chapman, Sian M. Henson, John M. Berge, David K. Dean, Nikesh R. Kotecha, Helen K. A. Morgan, Harshad K. Rami, Robert W. Ward, Mervyn Thompson, Shelagh Wilson, Stephen A. Smith, Michael A. Cawthorne, Michael J. Stock and Jonathan R. S. Arch
Journal of Pharmacology and Experimental Therapeutics June 1998, 285 (3) 1084-1095;

Article Information

vol. 285 no. 3 1084-1095
PubMed 
9618411
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received October 13, 1997
  • Accepted February 6, 1998
  • Published online June 1, 1998.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Matthew V. Sennitt1,2,
  2. Alberto J. Kaumann2,3,4,
  3. Peter Molenaar4,
  4. Lee J. Beeley1,
  5. Paul W. Young1,
  6. John Kelly1,
  7. Helen Chapman1,
  8. Sian M. Henson1,
  9. John M. Berge1,
  10. David K. Dean1,
  11. Nikesh R. Kotecha1,
  12. Helen K. A. Morgan1,
  13. Harshad K. Rami1,
  14. Robert W. Ward1,
  15. Mervyn Thompson1,
  16. Shelagh Wilson1,
  17. Stephen A. Smith1,
  18. Michael A. Cawthorne1,
  19. Michael J. Stock2 and
  20. Jonathan R. S. Arch1
  1. 1SmithKline Beecham Pharmaceuticals, Great Burgh, Epsom, Surrey, The Frythe, Welwyn, Herts and New Frontiers Science Park, Harlow, Essex, CM19 5AW, UK (L.J.B., P.W.Y., J.K., H.C., S.M.H., J.M.B., D.K.D., N.R.K., H.K.A.M., H.K.R., R.W.R., M.T., S.W., S.A.S., J.R.S.A.); 2St Georges Hospital Medical School, Tooting, London, SW17 0RE, UK (M.V.S., M.J.S.); 3The Babraham Institute, Babraham, Cambridge, CB2 4AT, UK (A.J.K.) and 4Department of Pharmacology, University of Melbourne, Victoria 3052, Australia (P.M., A.J.K.)
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    OtherAUTONOMIC PHARMACOLOGY

    The Contribution of Classical (β1/2-) and Atypical β-Adrenoceptors to the Stimulation of Human White Adipocyte Lipolysis and Right Atrial Appendage Contraction by Novel β3-Adrenoceptor Agonists of Differing Selectivities

    Matthew V. Sennitt, Alberto J. Kaumann, Peter Molenaar, Lee J. Beeley, Paul W. Young, John Kelly, Helen Chapman, Sian M. Henson, John M. Berge, David K. Dean, Nikesh R. Kotecha, Helen K. A. Morgan, Harshad K. Rami, Robert W. Ward, Mervyn Thompson, Shelagh Wilson, Stephen A. Smith, Michael A. Cawthorne, Michael J. Stock and Jonathan R. S. Arch
    Journal of Pharmacology and Experimental Therapeutics June 1, 1998, 285 (3) 1084-1095;
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