Prediction of Species Differences (Rats, Dogs, Humans) in theIn Vivo Metabolic Clearance of YM796 by the Liver fromIn Vitro Data

	Abstract	Full	Pdf
Jan 1999	1	2	4
Feb 1999	0	3	5
Mar 1999	1	3	4
Apr 1999	2	7	9
May 1999	0	1	1
Jun 1999	0	2	4
Jul 1999	0	2	2
Aug 1999	1	6	10
Sep 1999	1	2	5
Oct 1999	0	4	5
Nov 1999	1	4	3
Dec 1999	2	3	1
Jan 2000	0	1	1
Feb 2000	0	6	9
Mar 2000	2	9	7
Apr 2000	1	2	7
May 2000	0	1	3
Jun 2000	1	2	1
Jul 2000	0	2	11
Aug 2000	0	4	5
Sep 2000	0	4	8
Oct 2000	0	3	7
Nov 2000	0	2	3
Dec 2000	1	1	3
Jan 2001	3	5	5
Feb 2001	1	7	9
Mar 2001	1	5	11
Apr 2001	0	1	2
May 2001	4	2	6
Jun 2001	0	2	5
Jul 2001	0	4	5
Aug 2001	1	8	4
Sep 2001	0	3	10
Oct 2001	1	1	2
Nov 2001	0	0	5
Dec 2001	0	1	10
Jan 2002	0	6	7
Feb 2002	0	16	9
Mar 2002	1	2	2
Apr 2002	2	6	15
May 2002	0	5	6
Jun 2002	1	6	11
Jul 2002	0	11	14
Aug 2002	0	0	8
Sep 2002	1	1	10
Oct 2002	2	5	5
Nov 2002	1	9	13
Dec 2002	0	8	9
Jan 2003	2	4	16
Feb 2003	1	8	10
Mar 2003	0	3	10
Apr 2003	2	8	10
May 2003	1	3	6
Jun 2003	2	5	12
Jul 2003	5	16	15
Aug 2003	6	13	6
Sep 2003	8	18	13
Oct 2003	7	14	5
Nov 2003	6	21	7
Dec 2003	6	22	7
Jan 2004	11	22	17
Feb 2004	9	29	15
Mar 2004	9	32	8
Apr 2004	11	19	5
May 2004	16	20	18
Jun 2004	19	26	9
Jul 2004	20	33	15
Aug 2004	12	25	22
Sep 2004	13	24	16
Oct 2004	13	20	10
Nov 2004	10	20	5
Dec 2004	7	27	10
Jan 2005	12	30	19
Feb 2005	6	22	10
Mar 2005	4	16	9
Apr 2005	0	29	9
May 2005	5	36	16
Jun 2005	6	40	15
Jul 2005	3	22	10
Aug 2005	9	17	15
Sep 2005	7	14	8
Oct 2005	2	11	5
Nov 2005	3	9	14
Dec 2005	3	18	12
Jan 2006	3	12	4
Feb 2006	6	30	8
Mar 2006	2	14	8
Apr 2006	7	10	9
May 2006	3	17	11
Jun 2006	3	16	13
Jul 2006	6	17	14
Aug 2006	7	17	13
Sep 2006	12	28	15
Oct 2006	3	20	17
Nov 2006	8	20	19
Dec 2006	3	20	19
Jan 2007	5	20	10
Feb 2007	6	28	17
Mar 2007	7	22	10
Apr 2007	2	25	20
May 2007	11	18	14
Jun 2007	4	16	16
Jul 2007	2	28	16
Aug 2007	4	24	13
Sep 2007	2	18	16
Oct 2007	6	19	12
Nov 2007	5	12	8
Dec 2007	6	18	13
Jan 2008	2	9	5
Feb 2008	3	8	5
Mar 2008	6	16	9
Apr 2008	9	17	17
May 2008	6	14	6
Jun 2008	5	18	11
Jul 2008	6	10	9
Aug 2008	3	3	3
Sep 2008	13	12	13
Oct 2008	8	15	4
Nov 2008	11	15	10
Dec 2008	7	16	9
Jan 2009	6	10	8
Feb 2009	6	3	7
Mar 2009	10	10	6
Apr 2009	3	15	13
May 2009	2	10	8
Jun 2009	1	6	5
Jul 2009	4	9	8
Aug 2009	4	15	13
Sep 2009	4	11	6
Oct 2009	4	15	13
Nov 2009	5	27	6
Dec 2009	5	9	6
Jan 2010	7	8	8
Feb 2010	11	5	1
Mar 2010	10	12	7
Apr 2010	12	14	13
May 2010	17	12	8
Jun 2010	13	6	8
Jul 2010	16	11	10
Aug 2010	9	11	9
Sep 2010	10	13	7
Oct 2010	5	13	14
Nov 2010	7	12	10
Dec 2010	7	6	6
Jan 2011	12	12	11
Feb 2011	10	6	7
Mar 2011	11	8	9
Apr 2011	5	6	5
May 2011	5	2	10
Jun 2011	7	9	14
Jul 2011	7	3	12
Aug 2011	7	4	8
Sep 2011	14	10	16
Oct 2011	21	4	10
Nov 2011	12	5	13
Dec 2011	9	10	9
Jan 2012	12	12	14
Feb 2012	15	7	12
Mar 2012	17	10	21
Apr 2012	13	11	16
May 2012	22	11	12
Jun 2012	7	11	19
Jul 2012	9	12	19
Aug 2012	13	15	22
Sep 2012	11	13	29
Oct 2012	8	9	19
Nov 2012	9	10	23
Dec 2012	9	5	11
Jan 2013	7	8	16
Feb 2013	14	10	22
Mar 2013	9	9	26
Apr 2013	15	9	13
May 2013	21	7	22
Jun 2013	6	3	7
Jul 2013	4	3	9
Aug 2013	3	3	12
Sep 2013	10	3	9
Oct 2013	3	6	13
Nov 2013	1	8	4
Dec 2013	3	0	12
Jan 2014	6	3	8
Feb 2014	1	0	5
Mar 2014	8	5	7
Apr 2014	3	6	22
May 2014	4	3	13
Jun 2014	4	6	15
Jul 2014	11	15	23
Aug 2014	8	4	15
Sep 2014	7	2	13
Oct 2014	12	8	11
Nov 2014	7	8	7
Dec 2014	7	6	9
Jan 2015	11	6	9
Feb 2015	1	4	4
Mar 2015	4	7	16
Apr 2015	3	6	10
May 2015	3	6	16
Jun 2015	6	8	27
Jul 2015	4	21	16
Aug 2015	13	4	11
Sep 2015	2	8	12
Oct 2015	14	7	14
Nov 2015	5	9	12
Dec 2015	12	4	5
Jan 2016	5	9	16
Feb 2016	4	2	6
Mar 2016	9	9	16
Apr 2016	8	4	10
May 2016	7	5	13
Jun 2016	6	6	13
Jul 2016	5	7	19
Aug 2016	4	4	13
Sep 2016	3	8	14
Oct 2016	7	21	16
Nov 2016	2	21	16
Dec 2016	0	7	4
Jan 2017	1	14	17
Feb 2017	1	18	11
Mar 2017	0	14	7
Apr 2017	2	10	8
May 2017	0	13	9
Jun 2017	1	12	14
Jul 2017	2	4	16
Aug 2017	1	6	26
Sep 2017	1	11	17
Oct 2017	0	16	18
Nov 2017	1	11	16
Dec 2017	2	10	16
Jan 2018	2	13	16
Feb 2018	2	12	13
Mar 2018	1	10	10
Apr 2018	0	11	16
May 2018	3	19	20
Jun 2018	2	9	10
Jul 2018	1	16	16
Aug 2018	2	16	9
Sep 2018	1	7	13
Oct 2018	0	12	6
Nov 2018	0	18	19
Dec 2018	25	6	6
Jan 2019	24	3	7
Feb 2019	19	1	5
Mar 2019	28	6	14
Apr 2019	21	3	9
May 2019	19	8	5
Jun 2019	11	0	3
Jul 2019	8	0	1
Aug 2019	12	9	6
Sep 2019	13	2	2
Oct 2019	12	1	3
Nov 2019	40	3	9
Dec 2019	19	4	5
Jan 2020	23	6	4
Feb 2020	11	1	0
Mar 2020	22	7	4
Apr 2020	19	2	5
May 2020	19	2	3
Jun 2020	17	2	3
Jul 2020	10	1	1
Aug 2020	24	1	4
Sep 2020	23	3	2
Oct 2020	23	1	6
Nov 2020	16	0	4
Dec 2020	14	2	3
Jan 2021	16	10	4
Feb 2021	34	11	6
Mar 2021	15	3	5
Apr 2021	19	4	3
May 2021	24	3	4
Jun 2021	6	4	2
Jul 2021	7	1	1