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OtherDRUG METABOLISM AND DISPOSITION

The Prediction of Human Pharmacokinetic Parameters from Preclinical and In Vitro Metabolism Data

R. Scott Obach, James G. Baxter, Theodore E. Liston, B. Michael Silber, Barry C. Jones, Fiona Macintyre, David J. Rance and Philip Wastall
Journal of Pharmacology and Experimental Therapeutics October 1997, 283 (1) 46-58;
R. Scott Obach
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James G. Baxter
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Theodore E. Liston
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B. Michael Silber
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Barry C. Jones
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Fiona Macintyre
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David J. Rance
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Philip Wastall
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Article Information

vol. 283 no. 1 46-58
PubMed 
9336307

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received March 4, 1997
  • Accepted June 23, 1997
  • Published online October 1, 1997.

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. R. Scott Obach1,
  2. James G. Baxter1,
  3. Theodore E. Liston1,
  4. B. Michael Silber1,
  5. Barry C. Jones2,
  6. Fiona Macintyre2,
  7. David J. Rance2 and
  8. Philip Wastall2
  1. Departments of 1Drug Metabolism, Pfizer Central Research, Groton, Connecticut (R.S.O., J.G.B., T.E.L., B.M.S.), and 2Sandwich, Kent (B.C.J., F.M., D.J.R., P.W.), UK
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    Vol. 283, Issue 1
    1 Oct 1997
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    OtherDRUG METABOLISM AND DISPOSITION

    The Prediction of Human Pharmacokinetic Parameters from Preclinical and In Vitro Metabolism Data

    R. Scott Obach, James G. Baxter, Theodore E. Liston, B. Michael Silber, Barry C. Jones, Fiona Macintyre, David J. Rance and Philip Wastall
    Journal of Pharmacology and Experimental Therapeutics October 1, 1997, 283 (1) 46-58;

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    OtherDRUG METABOLISM AND DISPOSITION

    The Prediction of Human Pharmacokinetic Parameters from Preclinical and In Vitro Metabolism Data

    R. Scott Obach, James G. Baxter, Theodore E. Liston, B. Michael Silber, Barry C. Jones, Fiona Macintyre, David J. Rance and Philip Wastall
    Journal of Pharmacology and Experimental Therapeutics October 1, 1997, 283 (1) 46-58;
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