Journal of Pharmacology and Experimental Therapeutics: 281 (1)

April 01, 1997; Volume 281,Issue 1

ANALGESIA AND DRUGS OF ABUSE

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Hyperpolarizing Effects of Morphine, Clonidine and 2-Chloroadenosine in Myenteric Neurons Associated with Tolerance to Morphine
Jianzhong Meng, C. J. Malanga, Jian-Qiang Kong, David A. Taylor and William W. Fleming

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 41-47;
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Antisense Mapping of MOR-1 in Rats: Distinguishing between Morphine and Morphine-6β-glucuronide Antinociception
Grace C. Rossi, Liza Leventhal, Ying-Xin Pan, Jessica Cole, Wendy Su, Richard J. Bodnar and Gavril W. Pasternak

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 109-114;
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Putative kappa-2 Opioid Agonists Are Antihyperalgesic in a Rat Model of Inflammation
Janice Ho, Andrew J. Mannes, Ronald Dubner and Robert M. Caudle

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 136-141;
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Antinociceptive Effects of RB101, a Complete Inhibitor of Enkephalin-catabolizing Enzymes, Are Enhanced by a Cholecystokinin Type B Receptor Antagonist, as Revealed by Noxiously Evoked Spinal c-Fos Expression in Rats
Prisca Honoré, Jaroslava Buritova, Marie-Claude Fournié-Zaluski, Bernard P. Roques and Jean-Marie Besson

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 208-217;
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Comparative Pharmacokinetics and Pharmacodynamics of Remifentanil, Its Principle Metabolite (GR90291) and Alfentanil in Dogs
J. Frank Hoke, Francesca Cunningham, Michael K. James, Keith T. Muir and William E. Hoffman

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 226-232;
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Insulin Attenuates Formalin-Induced Nociceptive Response in Mice through a Mechanism that Is Deranged by Diabetes Mellitus
Nobuaki Takeshita and Isamu Yamaguchi

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 315-321;
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Pharmacogenetic Determinants of Codeine Induction by Rifampin: The Impact on Codeine’s Respiratory, Psychomotor and Miotic Effects
Yoseph Caraco, James Sheller and Alastair J. J. Wood

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 330-336;
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Body Temperature and Analgesic Effects of Selective Muand Kappa Opioid Receptor Agonists Microdialyzed into Rat Brain
Li Xin, Ellen B. Geller and Martin W. Adler

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 499-507;
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Characterization of Neonatal Rat Fentanyl Tolerance and Dependence
Suzanne R. Thornton and Forrest L. Smith

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 514-521;
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Opioids Binding Mu and DeltaReceptors Exhibit Diverse Efficacy in the Activation of G_i2and G_x/z Transducer Proteins in Mouse Periaqueductal Gray Matter
Javier Garzón, Antonio García-España and Pilar Sánchez-Blázquez

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 549-557;
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Phencyclidine Continuous Dosing Produces a Treatment Time-Dependent Regulation of Rat CYP2C11 Function, Protein Expression and mRNA Levels
S. R. Shelnutt, L. E. Cornett and S. M. Owens

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 574-581;
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Antisense Targeting of Delta Opioid Receptors in NG 108-15 Cells: Direct Correlation between Oligodeoxynucleotide Uptake and Receptor Density
Josephine Lai, Tracy J. Crook, Andrea Payne, Ronald M. Lynch and Frank Porreca

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 589-596;

AUTONOMIC PHARMACOLOGY

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Neuropeptide Y-Mediated Pressor Responses Following High-Frequency Stimulation of the Rat Sympathetic Nervous System
Brian Kennedy, Gregory H. Shen and Michael G. Ziegler

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 291-296;
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Mechanisms of the Atrium-Specific Positive Inotropic Activities of Quinidine- and Atropine-Like Agents in Rats
Xing Fei Deng, Shree Mulay, Sylvain Chemtob and Daya R. Varma

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 322-329;
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α-Adrenergic Activity and Cardiovascular Effects of Besipirdine HCl (HP 749) and Metabolite P7480 in Vitro and in the Conscious Rat and Dog
John W. Hubbard, Scott T. Nordstrom, Craig P. Smith, Karen M. Brooks, Lynn Laws-Ricker, Lily Zhou and Hugo M. Vargas

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 337-346;
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Interaction Between Histamine H₃ Receptors and Other Prejunctional Receptor Systems in the Isolated Guinea Pig Duodenum ^,
Enzo Poli, Cristina Pozzoli and Giulio Bertaccini

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 393-399;
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M2, M3 and M4, but not M1, Muscarinic Receptor Subtypes are Present in Rat Spinal Cord
A. U. Höglund and H. A. Baghdoyan

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 470-477;
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Characterization of Vanadyl Sulfate Effect on Vascular Contraction: Roles of Calcium and Tyrosine Phosphorylation
Anne Cadène, Florin Grigorescu, Jean-Jacques Serrano and Gérard Cros

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 491-498;

BEHAVIORAL PHARMACOLOGY

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Intracranial Self-Stimulation in Rats: Sensitization to an Opioid Antagonist Following Acute or Chronic Treatment with MuOpioid Agonists ^,
Keith W. Easterling and Stephen G. Holtzman

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 188-199;
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PNU-96415E, a Potential Antipsychotic Agent with Clozapine-Like Pharmacological Properties
A. H. Tang, S. R. Franklin, C. S. Himes, M. W. Smith and R. E. Tenbrink

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 440-447;

CARDIOVASCULAR PHARMACOLOGY

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Evidence for Functional Responses to Sensory Nerve Stimulation of Rat Small Mesenteric Veins
Amrita Ahluwalia and Patrick Vallance

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 9-14;
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Effect of Timing of Treatment of the Glyburide-Reversible Cardioprotective Activity of BMS-180448
Allen W. Gomoll, Russell A. Roth, Robert E. Swillo, Anne J. Baird, Carol S. Sargent, Ronald W. Behling, Harold J. Malone and Gary J. Grover

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 24-33;
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Class III Electrophysiologic Actions of Imidazole-Substituted Diheterabicyclononanes in Canine Myocardium
Eugene Patterson, Benjamin J. Scherlag, Subiah Sangiah, Gregory L. Garrison, Kevin M. Couch, K. Darrell Berlin and Ralph Lazzara

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 155-162;
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Cardiovascular Effects of Cholecystokinin-4 Are Mediated By the Cholecystokinin-B Receptor Subtype In the Conscious Guinea Pig and Dog
Anthony A. Fossa, Michael J. Depasquale, Jean Morrone, Stevin H. Zorn, Dianne Bryce, John A. Lowe and Stafford McLean

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 180-187;
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Glyceryl Nonivamide: A Capsaicin Derivative with Cardiac Calcitonin Gene-Related Peptide Releasing, K⁺ Channel Opening and Vasorelaxant Properties
Yi-Ching Lo, Jiunn-Ren Wu, Sheng-Nan Wu and Ing-Jun Chen

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 253-260;
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The Quasi-irreversible Nature of Endothelin Binding and G Protein-Linked Signaling in Cardiac Myocytes
Randa Hilal-Dandan, Sonia Villegas, Annette Gonzalez and Laurence L. Brunton

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 267-273;
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Spinal Muscarinic, Glutamatergic and GABAergic Receptor Systems in Cardiovascular Regulation
David S. Feldman and Jerry J. Buccafusco

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 274-283;
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Angiotensin II Potentiates Vasodilation of Rat Aorta by cAMP Elevating Agonists
Antonia Brizzolara-Gourdie and Jerry G. Webb

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 354-359;
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Effects of Class III Antiarrhythmic Drugs on Transient Outward and Ultra-rapid Delayed Rectifier Currents in Human Atrial Myocytes
Jianlin Feng, Zhiguo Wang, Gui-Rong Li and Stanley Nattel

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 384-392;
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Video-microscopic Assessment of the Role of Tissue Angiotensin-converting Enzyme in the Control of the Renal Microcirculation
P. M. Ter Wee, H. G. Forster and M. Epstein

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 434-439;
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l-Glutamine Inhibits Nitric Oxide Synthesis in Bovine Venular Endothelial Cells
Cynthia J. Meininger and Guoyao Wu

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 448-453;

CELLULAR AND MOLECULAR PHARMACOLOGY

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Activation of Phospholipase D by Endothelin-1 in Rat Myometrium. Role of Calcium and Protein Kinase C
Sandrine Naze, Hervé Le Stunff, Lien Dokhac, Gisèle Thomas and Simone Harbon

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 15-23;
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Effects of Alcohols on A-Type K⁺ Currents inLymnaea Neurons
S. I. Alekseev, A. S. Alekseev and M. C. Ziskin

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 84-92;
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High-Affinity Binding of DTZ323, a Novel Derivative of Diltiazem, to Rabbit Skeletal Muscle L-type Ca⁺⁺ Channels
Masafumi Hagiwara, Satomi Adachi-Akahane and Taku Nagao

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 173-179;
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Effects of Prolonged Ethinyl Estradiol Treatment on Calcium Channel Binding and In Vivo Calcium-Mediated Hemodynamic Responses in Ovariectomized Rats
Nancy Bowling, William E. Bloomquist, Marlene L. Cohen, Henry U. Bryant, Harlan W. Cole, David E. Magee, Ellen R. Rowley and Chris J. Vlahos

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 218-225;
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Suppression of Mammalian K⁺ Channel Family by Ebastine
Chang Mann Ko, Ivan Ducic, Jing Fan, Yaroslav M. Shuba and Martin Morad

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 233-244;
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Avermectin B_1a Binds to High- and Low-Affinity Sites with Dual Effects on the γ-Aminobutyric Acid-Gated Chloride Channel of Cultured Cerebellar Granule Neurons
Jian Huang and John E. Casida

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 261-266;
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Uptake and Release of [³H]Formycin Bvia Sodium-Dependent Nucleoside Transporters in Mouse Leukemic L1210/MA27.1 Cells
Stephanie L. Borgl and and Fiona E. Parkinson

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 347-353;
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Antagonism ofN-Methyl-d-aspartate-evoked Currents in Rat Cortical Cultures by ARL 15896AR
G. A. R. Mealing, T. H. Lanthorn, D. L. Small, M. A. Black, N. B. Laferriere and P. Morley

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 376-383;
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Suppression by Ethanol of Inducible Nitric Oxide Synthase Expression in C6 Glioma Cells
Julius D. Militante, Douglas L. Feinstein and Peter J. Syapin

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 558-565;

CHEMOTHERAPY/GENE THERAPY

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Pharmacokinetics of G3139, a Phosphorothioate Oligodeoxynucleotide Antisense to bcl-2, after Intravenous Administration or Continuous Subcutaneous Infusion to Mice
Florence I. Raynaud, Rosanne M. Orr, Phyllis M. Goddard, Heidi A. Lacey, Helen Lancashire, Ian R. Judson, Terry Beck, Bob Bryan and Finbarr E. Cotter

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 420-427;
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Influence of the Vitamin D Status on the Early Hepatic Response to Carcinogen Exposure in Rats
Ru-Kun He and Marielle Gascon-Barré

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 464-469;
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Influence of Drug Release Characteristics on the Therapeutic Activity of Liposomal Mitoxantrone
Howard J. Lim, Dana Masin, Thomas D. Madden and Marcel B. Bally

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 566-573;

DRUG METABOLISM AND DISPOSITION

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Effect of Antivenom on Venom Pharmacokinetics in Experimentally Envenomed Rabbits: Toward an Optimization of Antivenom Therapy
Gilles Rivière, Valérie Choumet, Françoise Audebert, Alain Sabouraud, Marcel Debray, Jean-Michel Scherrmann and Cassian Bon

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 1-8;
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Pharmacokinetics and Pharmacodynamics of Nandrolone Esters in Oil Vehicle: Effects of Ester, Injection Site and Injection Volume
Charles F. Minto, Christopher Howe, Susan Wishart, Ann J. Conway and David J. Handelsman

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 93-102;
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Inhibition of Cytochrome P450 2D6 Metabolism of Hydrocodone to Hydromorphone Does Not Importantly Affect Abuse Liability
Howard L. Kaplan, Usoa E. Busto, Godofredo J. Baylon, Siu W. Cheung, S. Victoria Otton, Gail Somer and Edward M. Sellers

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 103-108;
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Characterization of the Hepatic Canalicular Membrane Transport of a Model Oligopeptide: Ditekiren
Harumi Takahashi, Richard B. Kim, Patrick R. Perry and Grant R. Wilkinson

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 297-303;
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Multispecific Organic Anion Transporter Is Responsible for the Biliary Excretion of the Camptothecin Derivative Irinotecan and its Metabolites in Rats
Xiao-Yan Chu, Yukio Kato, Kayoko Niinuma, Ken-Ichi Sudo, Hideo Hakusui and Yuichi Sugiyama

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 304-314;
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In Vivo Evidence for Carrier-Mediated Efflux Transport of 3′-Azido-3′-Deoxythymidine and 2′,3′-Dideoxyinosine Across the Blood-Brain Barriervia a Probenecid-Sensitive Transport System
Katsuko Takasawa, Tetsuya Terasaki, Hiroshi Suzuki and Yuichi Sugiyama

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 369-375;
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Cytochrome P450 2E1 is the Principal Catalyst of Human Oxidative Halothane Metabolism in Vitro
Douglas K. Spracklin, Douglas C. Hankins, Jeannine M. Fisher, Kenneth E. Thummel and Evan D. Kharasch

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 400-411;
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Kinetics of Respiratory Depression in Rats Induced by Buprenorphine and its Metabolite, Norbuprenorphine
Michiteru Ohtani, Hajime Kotaki, Kenji Nishitateno, Yasufumi Sawada and Tatsuji Iga

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 428-433;
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Nitric Oxide-Mediated Inhibition of Cytochrome P450 by Interferon-γ in Human Hepatocytes
M. Teresa Donato, M. Isabel Guillén, Ramiro Jover, José V. Castell and M. José Gómez-Lechón

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 484-490;
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Differences in the Incidence of the CYP2C19Polymorphism Affecting the S-Mephenytoin Phenotype in Chinese Han and Bai Populations and Identification of a New RareCYP2C19 Mutant Allele
Zhou-Sheng Xiao, Joyce A. Goldstein, Hong-Guang Xie, Joyce Blaisdell, Wei Wang, Chang-Hong Jiang, Feng-Xiang Yan, Nan He, Song-Ling Huang, Zhen-Hua Xu and Hong-Hao Zhou

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 604-609;

ENDOCRINE PHARMACOLOGY

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The Effects of Chronic Cocaine Self-Administration on the Menstrual Cycle in Rhesus Monkeys
Nancy K. Mello, Jack H. Mendelson, Maureen Kelly, Nicolas Diaz-Migoyo and J. Wallis Sholar

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 70-83;
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Opioid Modulation of the Fetal Hypothalamic-Pituitary-Adrenal Axis: The Role of Receptor Subtypes and Route of Administration
Cindy C. Taylor, Dunli Wu, Yi Soong, Jenny S. Yee and Hazel H. Szeto

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 129-135;
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Tamoxifen and ICI 182,780 Interactions with Thyroid Hormone in the Ovariectomized-Thyroidectomized Rat
Vincent A. Dipippo and C. Andrew Powers

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 142-148;
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Hepatobiliary Excretion of Bile Acids and Rose Bengal in Streptozotocin-Induced and Genetic Diabetic Rats
Joy L. Stone, Joel B. Braunstein, Timothy M. Beaty, Ruth A. Sanders and John B. Watkins

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 412-419;

GASTROINTESTINAL PHARMACOLOGY

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The Neurotoxin 1-Methyl-4-phenylpyridinium Is a Substrate for the Canalicular Organic Cation/H⁺ Exchanger
Richard H. Moseley, Lena J. Zugger and Rebecca W. Van Dyke

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 34-40;
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Impaired Healing of Gastric Lesions in Streptozotocin-Induced Diabetic Rats: Effect of Basic Fibroblast Growth Factor
Koji Takeuchi, Koji Takehara, Kimihito Tajima, Shinichi Kato and Takuya Hirata

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 200-207;
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Somatostatin Inhibition of Acid and Histamine Release by Activation of Somatostatin Receptor Subtype 2 Receptors in Rats
K. Aurang, J. Wang and K. C. K. Lloyd

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 245-252;
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Combined Blockade of 5-HT₃- and 5-HT₄-Serotonin Receptors Inhibits Colonic Functions in Conscious Rats and Mice
Yasunori Nagakura, Akiko Kontoh, Kenichi Tokita, Masaaki Tomoi, Kyoichi Shimomura and Makoto Kadowaki

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 284-290;
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Preventive Effect of Rebamipide on Gastric Mucosal Cell Damage Evoked by Activation of Formyl-Methionyl-Leucyl-Phenylalanine Receptors of Rabbit Neutrophils
Chi Dae Kim and Ki Whan Hong

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 478-483;

IMMUNOPHARMACOLOGY

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The Hydroxylamine of Sulfamethoxazole Synergizes with FK506 and Cyclosporin A, Inhibiting T-Cell Proliferation
David A. Hess, Ingrid A. Bird, Wassim Y. Almawi and Michael J. Rieder

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 540-548;

NEUROPHARMACOLOGY

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Repeated Daily Cocaine Alters Subsequent Cocaine-induced Increase of Extracellular Dopamine in the Medial Prefrontal Cortex
Barbara A. Sorg, Debra L. Davidson, Peter W. Kalivas and Balakrishna M. Prasad

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 54-61;
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Fluoxetine Selectively Alters 5-Hydroxytryptamine_1Aand γ-Aminobutyric Acid_B Receptor-Mediated Hyperpolarization in Area CA1, but not Area CA3, Hippocampal Pyramidal Cells
Sheryl G. Beck, Susanne Birnstiel, Kue C. Choi and Wendy A. Pouliot

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 115-122;
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Kappa Opioid Receptor Tolerance in the Guinea Pig Hippocampus
Wenzhen Jin, Gregory W. Terman and Charles Chavkin

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 123-128;
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Metabotropic Glutamate Receptor Agonists Increase Release of Soluble Amyloid Precursor Protein Derivatives from Rat Brain Cortical and Hippocampal Slices
Ismail H. Ulus and Richard J. Wurtman

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 149-154;
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Activation of the Locus Coeruleus Noradrenergic System by Intracoerulear Microinfusion of Corticotropin-Releasing Factor: Effects on Discharge Rate, Cortical Norepinephrine Levels and Cortical Electroencephalographic Activity
Andre L. Curtis, Sandra M. Lechner, Luis A. Pavcovich and Rita J. Valentino

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 163-172;
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Nonstriatal Dopamine D1 Receptors Regulate Striatal Acetylcholine Release In Vivo
Elio Acquas, Catriona Wilson and Hans C. Fibiger

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 360-368;
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The Selective Dopamine D1 Receptor Agonist A-86929 Maintains Efficacy with Repeated Treatment in Rodent and Primate Models of Parkinson’s Disease
K. E. Asin, E. F. Domino, A. Nikkel and K. Shiosaki

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 454-459;
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Differential Regulation of Dopamine Transporter after Chronic Self-administration of Bupropion and Nomifensine
Srihari R. Tella, Bruce Ladenheim and Jean Lud Cadet

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 508-513;
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Identification of Insulin-Like Growth Factor Binding Protein-2 as a Biochemical Surrogate Marker for the in Vivo Effects of Recombinant Human Insulin-Like Growth Factor-1 in Mice
Ratan V. Bhat, Thomas M. Engber, Yuan Zhu, Matthew S. Miller and Patricia C. Contreras

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 522-530;
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Selective Action of Acute Systemic Clozapine on Acetylcholine Release in the Rat Prefrontal Cortex by Reference to the Nucleus Accumbens and Striatum
M. A. Parada, L. Hernandez, M. Puig De Parada, P. Rada and E. Murzi

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 582-588;
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Down-Regulation of the D1 and D5 Dopamine Receptors in the Primate Prefrontal Cortex by Chronic Treatment with Antipsychotic Drugs
Michael S. Lidow, John D. Elsworth and Patricia S. Goldman-Rakic

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 597-603;

PROSTAGLANDINS, LEUKOTRIENES AND OTHER EICOSANOIDS

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Inhibition by Boswellic Acids of Human Leukocyte Elastase
Hasan Safayhi, Beatrice Rall, Eckart-Roderich Sailer and Hermann P T. Ammon

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 460-463;

PULMONARY PHARMACOLOGY

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Functional Evidence of Excitatory M₁ Receptors in the Rabbit Airway
Shigeji Matsumoto

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 531-539;

RENAL PHARMACOLOGY

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Alpha-2a/d Adrenoceptor Subtype Stimulation by Guanfacine Increases Osmolar Clearance
H. D. Intengan and D. D. Smyth

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 48-53;
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Dexmedetomidine Inhibits Osmotic Water Permeability in the Rat Cortical Collecting Duct
Alexander J. Rouch, Lúcia H. Kudo and Connie Hébert

Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 62-69;

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Table of Contents

ANALGESIA AND DRUGS OF ABUSE

AUTONOMIC PHARMACOLOGY

BEHAVIORAL PHARMACOLOGY

CARDIOVASCULAR PHARMACOLOGY

CELLULAR AND MOLECULAR PHARMACOLOGY

CHEMOTHERAPY/GENE THERAPY

DRUG METABOLISM AND DISPOSITION

ENDOCRINE PHARMACOLOGY

GASTROINTESTINAL PHARMACOLOGY

IMMUNOPHARMACOLOGY

NEUROPHARMACOLOGY

PROSTAGLANDINS, LEUKOTRIENES AND OTHER EICOSANOIDS

PULMONARY PHARMACOLOGY

RENAL PHARMACOLOGY

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