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OtherDRUG METABOLISM AND DISPOSITION

Carrier-Mediated Active Transport of the Glucuronide and Sulfate of 6-Hydroxy-5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl) benzothiazole (E3040) into Rat Liver: Quantitative Comparison of Permeability in Isolated Hepatocytes, Perfused Liver and Liver in Vivo

Osamu Takenaka, Toru Horie, Hiroshi Suzuki and Yuichi Sugiyama
Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 948-958;

Article Information

vol. 280 no. 2 948-958
PubMed 
9023311
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received May 24, 1996
  • Accepted October 30, 1996
  • Published online February 1, 1997.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Osamu Takenaka1,
  2. Toru Horie1,
  3. Hiroshi Suzuki2 and
  4. Yuichi Sugiyama2
  1. 1Tsukuba Research Laboratories, Eisai Co., Ltd., Tokodai, Tsukuba-shi, Ibaraki 300-26, Japan (O.T., T.H.) and 2Faculty of Pharmaceutical Sciences, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113, Japan (H.S., Y.S.)
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    OtherDRUG METABOLISM AND DISPOSITION

    Carrier-Mediated Active Transport of the Glucuronide and Sulfate of 6-Hydroxy-5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl) benzothiazole (E3040) into Rat Liver: Quantitative Comparison of Permeability in Isolated Hepatocytes, Perfused Liver and Liver in Vivo

    Osamu Takenaka, Toru Horie, Hiroshi Suzuki and Yuichi Sugiyama
    Journal of Pharmacology and Experimental Therapeutics February 1, 1997, 280 (2) 948-958;
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