Journal of Pharmacology and Experimental Therapeutics: 280 (2)

February 01, 1997; Volume 280,Issue 2

ANALGESIA AND DRUGS OF ABUSE

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Evidence that Tolerance and Dependence of Guinea Pig Myenteric Neurons to Opioids Is a Function of Altered Electrogenic Sodium-Potassium Pumping
Jian-Qiang Kong, Judith A. Leedham, David A. Taylor and William W. Fleming

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 593-599;
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Delta-1 Opioid Receptor-Mediated Antinociceptive Properties of a Nonpeptidic Delta Opioid Receptor Agonist, (−)TAN-67, in the Mouse Spinal Cord
Leon F. Tseng, Minoru Narita, Hirokazu Mizoguchi, Kohji Kawai, Akira Mizusuna, Junzo Kamei, Tsutomu Suzuki and Hiroshi Nagase

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 600-605;
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Efficacy of Spinal NMDA Receptor Antagonism in Formalin Hyperalgesia and Nerve Injury Evoked Allodynia in the Rat
Sandra R. Chaplan, Annika B. Malmberg and Tony L. Yaksh

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 829-838;
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Antiinflammatory and Analgesic Activity of an Inhibitor of Neuropeptide Amidation
Alison A. Ogonowski, Sheldon W. May, Allison B. Moore, Lynn T. Barrett, Cindy L. O’Bryant and Stanley H. Pollock

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 846-853;
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Early Nociceptive Events Influence the Temporal Profile, but not the Magnitude, of the Tonic Response to Subcutaneous Formalin: Effects with Remifentanil
Bradley K. Taylor, M. Alex Peterson and Allan I. Basbaum

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 876-883;
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Common Quantitative Trait Loci for Alcohol-Related Behaviors and Central Nervous System Neurotensin Measures: Hypnotic and Hypothermic Effects
V. Gene Erwin, Paul D. Markel, Thomas E. Johnson, Vaughn M. Gehle and Byron C. Jones

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 911-918;
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Common Quantitative Trait Loci for Alcohol-Related Behaviors and Central Nervous System Neurotensin Measures: Locomotor Activation
V. Gene Erwin, Richard A. Radcliffe, Vaughn M. Gehle and Byron C. Jones

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 919-926;
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Naloxone-Reversible Antinociception by Paracetamol in the Rat
L. A. Pini, G. Vitale, A. Ottani and M. Sandrini

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 934-940;
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Tolerance to μ-Opioid Receptor Agonists but not Cross-tolerance to γ-Aminobutyric Acid_B Receptor Agonists in Arcuate A₁₂ Dopamine Neurons with Chronic Morphine Treatment
Edward J. Wagner, Ge Zhang, Andre H. Lagrange, Oline K. Rønnekleiv and Martin J. Kelly

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 1057-1064;

AUTONOMIC PHARMACOLOGY

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Adenosine Triphosphate Attenuates Renal Sympathetic Nerve Activity Through Left Ventricular Chemosensitive Receptors
Chikuni Taneyama, Kirk T. Benson, Peter G. Hild and Hiroshi Goto

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 570-575;
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Positive Feedback Modulation of Acetylcholine Release from Isolated Rat Superior Cervical Ganglion
Shang-Dong Liang and E. Sylvester Vizi

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 650-655;
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Sino-Aortic Denervation Causes Right Atrial BetaAdrenoceptor Down-Regulation
Angelina Zanesco, Regina C. Spadari-Bratfisch and Louis A. Barker

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 677-685;
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Differential Involvement of Serotonin 2A/C and Thromboxane A₂/Prostanoid Receptors in High- vs.Low-Shear Rate Arterial Thrombosis in Rabbits
Jean-Pierre Valentin, Sylvie Vieu, Frédéric Bertolino, Philippe Fauré and Gareth W. John

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 761-769;
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Effects of LY215490, a Competitive α-Amino-3-Hydroxy-5-Methylisoxazole-4-Propionic Acid (AMPA) Receptor Antagonist, on the Micturition Reflex in the Rat
Mitsuharu Yoshiyama, James R. Roppolo and William C. de Groat

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 894-904;
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Affinity and Selectivity of PD156707, A Novel Nonpeptide Endothelin Antagonist, for Human ET_A and ET_BReceptors
Janet J. Maguire, Rhoda E. Kuc and Anthony P. Davenport

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 1102-1108;

BEHAVIORAL PHARMACOLOGY

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The Reinforcing and Discriminative Stimulus Effects of the Novel Cocaine Analog 2β-Propanoyl-3β-(4-Tolyl)-Tropane in Rhesus Monkeys
Michael A. Nader, Kathleen A. Grant, Huw M. L. Davies, Robert H. Mach and Steven R. Childers

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 541-550;
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Pharmacological Activity and Safety Profile of P10358, a Novel, Orally Active Acetylcholinesterase Inhibitor for Alzheimer’s Disease
Craig P. Smith, Gina M. Bores, Wayne Petko, Mary Li, David E. Selk, Douglas K. Rush, Fernando Camacho, James T. Winslow, Rod Fishkin, Dana M. Cunningham, Karen M. Brooks, Joachim Roehr, Harold B. Hartman, Larry Davis and Hugo M. Vargas

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 710-720;
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Genetic Differences in Behavioral Sensitivity to a Neuroactive Steroid
Deborah A. Finn, Amanda J. Roberts, Frank Lotrich and Edward J. Gallaher

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 820-828;
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Self-Injurious Behavior and Dopaminergic Neuron System in Neonatal 6-Hydroxydopamine-Lesioned Rat: 1. Dopaminergic Neurons and Receptors
Chihiro Yokoyama and Hitoshi Okamura

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 1016-1030;
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Self-Injurious Behavior and Dopaminergic Neuron System in Neonatal 6-Hydroxydopamine-Lesioned Rat: 2. Intracerebral Microinjection of Dopamine Agonists and Antagonists
Hitoshi Okamura, Tsuyoshi Murakami, Chihiro Yokoyama, Toru Nakamura and Yasuhiko Ibata

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 1031-1037;

CARDIOVASCULAR PHARMACOLOGY

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Adenosine A₁ Receptor Blockade Does Not Abolish the Cardioprotective Effects of the Adenosine Triphosphate-sensitive Potassium Channel Opener Bimakalim
Garrett J. Gross, David A. Mei, Paul G. Sleph and Gary J. Grover

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 533-540;
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Nonpeptide Endothelin Receptor Antagonists. VIII: Attenuation of Acute Hypoxia-Induced Pulmonary Hypertension in the Dog
Robert N. Willette, Eliot H. Ohlstein, Marcus P. Mitchell, Charles F. Sauermelch, George R. Beck, Mark A. Luttmann and Douglas W. P. Hay

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 695-701;
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Evidence against a Cytochrome P450-Derived Reactive Oxygen Species as the Mediator of the Nitric Oxide-Independent Vasodilator Effect of Bradykinin in the Perfused Heart of the Rat
D. Fulton, J. C. McGiff, M. S. Wolin, P. Kaminski and J. Quilley

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 702-709;
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Comparison between Alpha-1 Adrenoceptor-Mediated and Beta Adrenoceptor-Mediated Inotropic Components Elicited by Norepinephrine in Failing Human Ventricular Muscle
Tor Skomedal, Kjell Borthne, Halfdan Aass, Odd Geiran and Jan-Bjørn Osnes

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 721-729;
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The Effect of Hydralazine on the Development of Tolerance to Continuous Nitroglycerin
John D. Parker, Andrea B. Parker, Bernice Farrell and John O. Parker

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 866-875;

CELLULAR AND MOLECULAR PHARMACOLOGY

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Direct Block of Voltage-Sensitive Sodium Channels by Genistein, A Tyrosine Kinase Inhibitor
Christophe Paillart, Edmond Carlier, Denis Guedin, Bénédicte Dargent and François Couraud

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 521-526;
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Nitrous Oxide Enhances Na⁺/Ca⁺⁺Exchange in the Neuroblastoma Cell Line SK-N-SH
M. C. Resendes, G. C. Kalogeros, S. J. Dixon and R. B. Philp

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 795-801;
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[³H]Inositol Polyphosphate Metabolism in Muscarinic Cholinoceptor-Stimulated Airways Smooth Muscle: Accumulation of [³H]inositol 4,5 Bisphosphate Via a Lithium-Sensitive Inositol Polyphosphate 1-Phosphatase
Barbara J. Lynch, Miratul M. K. Muqit, Trevor R. Walker and Edwin R. Chilvers

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 974-982;
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Different B₁ Kinin Receptor Expression and Pharmacology in Endothelial Cells of Different Origins and Species
Paulus Wohlfart, Jürgen Dedio, Klaus Wirth, Bernward A. Schölkens and Gabriele Wiemer

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 1109-1116;

DEVELOPMENTAL PHARMACOLOGY

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Oxidative Stress Regulates the Expression and Activity of Transcription Factor Activator Protein-1 in Rat Conceptus
Terence R. S. Ozolinš and Barbara F. Hales

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 1085-1093;

DRUG METABOLISM AND DISPOSITION

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Acetaldehyde as Well as Ethanol Is Metabolized by Human CYP2E1
Satoru Kunitoh, Susumu Imaoka, Toyoko Hiroi, Yoshiyasu Yabusaki, Takeyuki Monna and Yoshihiko Funae

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 527-532;
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Quantitative Evaluation of Brain Distribution and Blood-Brain Barrier Efflux Transport of Probenecid in Rats by Microdialysis: Possible Involvement of the Monocarboxylic Acid Transport System
Yoshiharu Deguchi, Kenji Nozawa, Shizuo Yamada, Yoshinari Yokoyama and Ryohei Kimura

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 551-560;
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Aging and Drug Interactions. III. Individual and Combined Effects of Cimetidine and Ciprofloxacin on Theophylline Metabolism in Healthy Male and Female Nonsmokers
Cho-Ming Loi, Beverly M. Parker, Barry J. Cusack and Robert E. Vestal

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 627-637;
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Active Transport of Nitrofurantoin Across the Mammary EpitheliumIn Vivo
Frank W. Kari, Robert Weaver and Margaret C. Neville

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 664-668;
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Active Transport of Nitrofurantoin Across a Mouse Mammary Epithelial Monolayer
Villi S. Toddywalla, Frank W. Kari and Margaret C. Neville

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 669-676;
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Inhibition by Omeprazole of Proguanil Metabolism: Mechanism of the Interaction In Vitro and Prediction of In Vivo Results from the In VitroExperiments
Christian Funck-Brentano, Laurent Becquemont, Anne Leneveu, Annie Roux, Patrice Jaillon and Philippe Beaune

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 730-738;
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In Vivo and In Vitro Evidence for Nonrestricted Transport of 2′,7′-Bis(2-Carboxyethyl)-5(6)-Carboxyfluorescein Tetraacetoxymethyl Ester at the Blood-Brain Barrier
Tomoko Hirohashi, Tetsuya Terasaki, Minoru Shigetoshi and Yuichi Sugiyama

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 813-819;
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Identification of Cytochrome P450 Isoforms Involved in CitalopramN-Demethylation by Human Liver Microsomes
Kaoru Kobayashi, Kan Chiba, Tomomi Yagi, Noriaki Shimada, Tomoyoshi Taniguchi, Toru Horie, Masayoshi Tani, Toshinori Yamamoto, Takashi Ishizaki and Yukio Kuroiwa

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 927-933;
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Carrier-Mediated Active Transport of the Glucuronide and Sulfate of 6-Hydroxy-5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl) benzothiazole (E3040) into Rat Liver: Quantitative Comparison of Permeability in Isolated Hepatocytes, Perfused Liver and Liver in Vivo
Osamu Takenaka, Toru Horie, Hiroshi Suzuki and Yuichi Sugiyama

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 948-958;
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Biotransformation of Parathion in Human Liver: Participation of CYP3A4 and its Inactivation during Microsomal Parathion Oxidation
Alison M. Butler and Michael Murray

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 966-973;
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Pharmacokinetic-Pharmacodynamic Contributions to the Convulsant Activity of Pefloxacin and Norfloxacin in Rats
Annie Delon, François Huguet, Philippe Courtois, Jean-Michel Vierfond, Serge Bouquet and William Couet

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 983-987;
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Distribution of Clodronate in the Bone of Adult Rats and Its Effects on Trabecular and Cortical Bone
T. Österman, T. Virtamo, K. Kippo, L. Laurén, I. Pasanen, R. Hannuniemi and R. Sellman

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 1051-1056;

ENDOCRINE PHARMACOLOGY

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Slow-Release Clodronate in Prevention of Inflammation and Bone Loss Associated with Adjuvant Arthritis
T. Österman, T. Virtamo, L. Laurén, K. Kippo, I. Pasanen, R. Hannuniemi, K. Väänänen and R. Sellman

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 1001-1007;

GASTROINTESTINAL PHARMACOLOGY

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Morphine Tolerance and Dependence in the Rat Intestine In Vivo
Cynthia L. Williams, Cynthia C. Bihm, Gary C. Rosenfeld and Thomas F. Burks

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 656-663;
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Size-Dependent Permeability of Hydrophilic Probes Across Rabbit Colonic Epithelium
Hamidreza Ghandehari, Philip L. Smith, Harma Ellens, Ping-Yang Yeh and Jindřich Kopeček

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 747-753;
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Central Injection of a New Corticotropin-Releasing Factor (CRF) Antagonist, Astressin, Blocks CRF- and Stress-Related Alterations of Gastric and Colonic Motor Function
Vicente Martínez, Jean Rivier, Lixin Wang and Yvette Taché

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 754-760;
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An ICAM-1 Antisense Oligonucleotide Prevents and Reverses Dextran Sulfate Sodium-Induced Colitis in Mice
C. Frank Bennett, Doug Kornbrust, Scott Henry, Kim Stecker, Randy Howard, Scott Cooper, Sheryl Dutson, William Hall and Henry I. Jacoby

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 988-1000;
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The Effect of Inhibitors of Inducible Nitric Oxide Synthase on Chronic Colitis in the Rhesus Monkey
Karen A. Ribbons, Mark G. Currie, Jane R. Connor, Pamela T. Manning, Phillip C. Allen, Peter Didier, Marion S. Ratterree, David A. Clark and Mark J. S. Miller

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 1008-1015;
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Effects of Cyclosporine or FK506 in Chronic Colitis
Satoshi Aiko, Elaine M. Conner, John A. Fuseler and Matthew B. Grisham

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 1075-1084;

IMMUNOPHARMACOLOGY

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Induction of Prostaglandin H Synthase-2 and Tumor Necrosis Factor-α in Human Amnionic WISH Cells by Various Stimuli Occurs Through Distinct Intracellular Mechanisms
Keren I. Hulkower, Ellen R. Otis, Junling Li, Bruce W. Ennis, David J. Cugier, Randy L. Bell, George W. Carter and Keith B. Glaser

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 1065-1074;

NEUROPHARMACOLOGY

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Dopamine Receptor Subtypes: Differential Regulation after 8 Months Treatment with Antipsychotic Drugs
Wouter J. Florijn, Frank I. Tarazi and Ian Creese

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 561-569;
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High-affinity Agonist Binding Is Not Sufficient for Agonist Efficacy at 5-Hydroxytryptamine_2A Receptors: Evidence in Favor of a Modified Ternary Complex Model
B. L. Roth, M. S. Choudhary, N. Khan and A. Z. Uluer

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 576-583;
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Characterization of Haloperidol and Trifluperidol as Subtype-Selective N-Methyl-d-Aspartate (NMDA) Receptor Antagonists Using [³H]TCP and [³H]Ifenprodil Binding in Rat Brain Membranes
Linda L. Coughenour and John J. Cordon

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 584-592;
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NR1 and NR2 Subunit Contributions to N-Methyl-d-aspartate Receptor Channel Blocker Pharmacology
Daniel T. Monaghan and Heidi Larsen

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 614-620;
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Voltage-Dependent Calcium Channels as Targets for Convulsant and Anticonvulsant Alkyl-Substituted Thiobutyrolactones
Robert A. Gross, Douglas F. Covey and James A. Ferrendelli

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 686-694;
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Differential Development and Characterization of Rapid Acute Neuronal Tolerance to the Depressant Effects of Ethanol on Cerebellar Purkinje Neurons of Low-alcohol-sensitive and High-alcohol-sensitive Rats
B. J. Pearson, D. P. Donatelli, R. K. Freund and M. R. Palmer

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 739-746;
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LY303870, a Centrally Active Neurokinin-1 Antagonist with a Long Duration of Action
S. Iyengar, P. A. Hipskind, D. R. Gehlert, D. Schober, K. L. Lobb, J. A. Nixon, D. R. Helton, M. J. Kallman, S. Boucher, R. Couture, D. L. Li and R. M. A. Simmons

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 774-785;
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Biochemical and Pharmacological Activities of SR 142948A, a New Potent Neurotensin Receptor Antagonist
Danielle Gully, Bernard Labeeuw, Robert Boigegrain, Florence Oury-Donat, André Bachy, Martine Poncelet, Régis Steinberg, Marie Françoise Suaud-Chagny, Vincent Santucci, Natalio Vita, Florence Pecceu, Catherine Labbé-Jullié, Patrick Kitabgi, Philippe Soubrié, Gérard Le Fur and Jean Pierre Maffrand

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 802-812;
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Inhibition of Reinforcing Effects of Morphine and Motivational Aspects of Naloxone-Precipitated Opioid Withdrawal by N-Methyl-d-aspartate Receptor Antagonist, Memantine
Piotr Popik and Wojciech Danysz

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 854-865;
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Glucocorticoids Regulate the Expression of Adenosine A₁ but not A_2A Receptors in Rat Brain
Per Svenningsson and Bertil B. Fredholm

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 1094-1101;

PROSTAGLANDINS, LEUKOTRIENES AND OTHER EICOSANOIDS

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Differential Inhibition of Murine Prostaglandin Synthase-1 and -2 by Nonsteroidal Anti-Inflammatory Drugs Using Exogenous and Endogenous Sources of Arachidonic Acid
Patricia C. Chulada and Robert Langenbach

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 606-613;
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Effect of Lobaric Acid on Cysteinyl-Leukotriene Formation and Contractile Activity of Guinea Pig Taenia Coli
Stefan R. Gissurarson, Stefan B. Sigurdsson, Hildebert Wagner and Kristin Ingolfsdottir

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 770-773;

PULMONARY PHARMACOLOGY

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The Phosphodiesterase Type 4 (PDE4) Inhibitor CP-80,633 Elevates Plasma Cyclic AMP Levels and Decreases Tumor Necrosis Factor-α (TNFα) Production in Mice: Effect of Adrenalectomy
John B. Cheng, John W. Watson, Christopher J. Pazoles, James D. Eskra, Richard J. Griffiths, Victoria L. Cohan, Claudia R. Turner, Henry J. Showell and E. Roy Pettipher

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 621-626;
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Nonpeptide Endothelin Receptor Antagonists. IX. Characterization of Endothelin Receptors in Guinea Pig Bronchus With SB 209670 and Other Endothelin Receptor Antagonists
Douglas W. P. Hay and Mark A. Luttmann

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 959-965;

RENAL PHARMACOLOGY

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Neutrophils Accentuate Renal Cold Ischemia-Reperfusion Injury. Dose-Dependent Protective Effect of a Platelet-Activating Factor Receptor Antagonist
M. Riera, J. Torras, I. Herrero, J. Valles, M. Paubert-Braquet, J. M. Cruzado, J. Alsina and J. M. Grinyo

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 786-794;
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Effects of Uricosuric and Antiuricosuric Agents on Urate Transport in Human Brush-Border Membrane Vesicles
Françoise Roch-Ramel, Barbara Guisan and Jacques Diezi

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 839-845;
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Effects of Sarafotoxin S6c on Antidiuresis and Norepinephrine Overflow Induced by Stimulation of Renal Nerves in Anesthetized Dogs
Gen Matsuo, Yasuo Matsumura, Kiyoshi Tadano and Shiro Morimoto

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 905-910;
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Evidence that the Organic Cation/H⁺ Exchanger in the Brush Border Membrane of Dog Kidney Is a 41-kDa Protein
Janice S. Gilsdorf, James F. Rebbeor and Peter D. Holohan

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 1043-1050;

TOXICOLOGY

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Cisplatin-Induced Nephrotoxicity in Porcine Proximal Tubular Cells: Mitochondrial Dysfunction by Inhibition of Complexes I to IV of the Respiratory Chain
Marieke Kruidering, Bob Van De Water, Emile De Heer, Gerard J. Mulder and J. Fred Nagelkerke

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 638-649;
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Disposition of Amodiaquine and Related Antimalarial Agents in Human Neutrophils: Implications for Drug Design
D. J. Naisbitt, J. E. Ruscoe, D. Williams, P. M. O’Neill, M. Pirmohamed and B. K. Park

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 884-893;
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Nitric Oxide and the Neurotoxic Effects of Methamphetamine and 3,4-Methylenedioxymethamphetamine
Terri Taraska and Kevin T. Finnegan

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 941-947;
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The Long-Acting Parenteral Iron Chelator, Hydroxyethyl Starch-Deferoxamine, Fails to Protect against Alcohol-Induced Liver Injury in Rats
S. M. Hossein Sadrzadeh, Philip E. Hallaway and Amin A. Nanji

Journal of Pharmacology and Experimental Therapeutics February 1997, 280 (2) 1038-1042;

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Table of Contents

ANALGESIA AND DRUGS OF ABUSE

AUTONOMIC PHARMACOLOGY

BEHAVIORAL PHARMACOLOGY

CARDIOVASCULAR PHARMACOLOGY

CELLULAR AND MOLECULAR PHARMACOLOGY

DEVELOPMENTAL PHARMACOLOGY

DRUG METABOLISM AND DISPOSITION

ENDOCRINE PHARMACOLOGY

GASTROINTESTINAL PHARMACOLOGY

IMMUNOPHARMACOLOGY

NEUROPHARMACOLOGY

PROSTAGLANDINS, LEUKOTRIENES AND OTHER EICOSANOIDS

PULMONARY PHARMACOLOGY

RENAL PHARMACOLOGY

TOXICOLOGY

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