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Abstract

Imipramine-induced inactivation of a cytochrome P450 2D enzyme in rat liver microsomes: in relation to covalent binding of its reactive intermediate.

Y Masubuchi, S Igarashi, T Suzuki, T Horie and S Narimatsu
Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 724-731;

Article Information

vol. 279 no. 2 724-731
PubMed 
8930177
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Published online November 1, 1996.

Author Information

  1. Y Masubuchi,
  2. S Igarashi,
  3. T Suzuki,
  4. T Horie and
  5. S Narimatsu
  1. Laboratory of Biopharmaceutics, Faculty of Pharmaceutical Sciences, Chiba University, Japan.

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    Abstract

    Imipramine-induced inactivation of a cytochrome P450 2D enzyme in rat liver microsomes: in relation to covalent binding of its reactive intermediate.

    Y Masubuchi, S Igarashi, T Suzuki, T Horie and S Narimatsu
    Journal of Pharmacology and Experimental Therapeutics November 1, 1996, 279 (2) 724-731;
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