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Journal of Pharmacology and Experimental Therapeutics

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Table of Contents

November 01, 1996; Volume 279,Issue 2

Article

  • You have access
    IN MEMORIAM
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 443-S;
  • You have access
    Synergistic behavioral interaction between ethanol and clonidine in rats: role of alpha-2 adrenoceptors.
    L Mao and A A Abdel-Rahman
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 443-449;
  • You have access
    Effects of transdermal nicotine delivery on measures of acute nicotine withdrawal.
    W B Pickworth, R V Fant, M F Butschky and J E Henningfield
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 450-456;
  • You have access
    Pharmacological characterization of inward current evoked by N-methyl-D-aspartate in dopamine neurons in the rat brain slice.
    Y N Wu and S W Johnson
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 457-463;
  • You have access
    Mechanical and energetic effects of cromakalim on guinea pig left ventricular papillary muscle.
    T Joseph, C Coirault, L Ducros and Y Lecarpentier
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 464-471;
  • You have access
    Anti-interleukin 4 antibody and indomethacin synergistic effect on B16 melanoma tumor progression.
    C Blaya, J Crespo, A Crespo and S F Aliño
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 472-477;
  • You have access
    Aging and glucocorticoids: effects on cell signaling mediated through adenylyl cyclase.
    T A Slotkin, L Thai, E C McCook, J L Saleh, J Zhang and F J Seidler
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 478-491;
  • You have access
    Anticonvulsant and behavioral profile of L-701,324, a potent, orally active antagonist at the glycine modulatory site on the N-methyl-D-aspartate receptor complex.
    L J Bristow, P H Hutson, J J Kulagowski, P D Leeson, S Matheson, F Murray, D Rathbone, K L Saywell, L Thorn, A P Watt and M D Tricklebank
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 492-501;
  • You have access
    Peripheral morphine analgesia: synergy with central sites and a target of morphine tolerance.
    Y A Kolesnikov, S Jain, R Wilson and G W Pasternak
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 502-506;
  • You have access
    In vitro biotransformation of dynorphin A (1-17) is similar in human and rhesus monkey blood as studied by matrix-assisted laser desorption/ionization mass spectrometry.
    J Yu, E R Butelman, J H Woods, B T Chait and M J Kreek
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 507-514;
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    Pharmacological properties of acquired excitotoxicity in Chinese hamster ovary cells transfected with N-methyl-D-aspartate receptor subunits.
    F A Boeckman and E Aizenman
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 515-523;
  • You have access
    Effects of naltrexone on response to intravenous cocaine, hydromorphone and their combination in humans.
    S L Walsh, J T Sullivan, K L Preston, J E Garner and G E Bigelow
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 524-538;
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    N-cyclobutylmethyl analog of normorphinone, N-CBM-TAMO: a short-term opioid agonist and long-term Mu-selective irreversible opioid antagonist.
    J Y Xu, A Seyed-Mozaffari, S Archer and J M Bidlack
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 539-547;
  • You have access
    Nephrotoxicity of acetaminophen in male Wistar rats: role of hepatically derived metabolites.
    L Trumper, L A Monasterolo and M M Elías
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 548-554;
  • You have access
    Molecular basis and species specificity of high affinity binding of vasoactive intestinal polypeptide by the rat secretin receptor.
    M H Holtmann, E M Hadac, C D Ulrich and L J Miller
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 555-560;
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    Long-term studies on anticonvulsant tolerance and withdrawal characteristics of benzodiazepine receptor ligands in different seizure models in mice. I. Comparison of diazepam, clonazepam, clobazam and abecarnil.
    W Löscher, C Rundfeldt, D Hönack and U Ebert
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 561-572;
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    Long-term studies on anticonvulsant tolerance and withdrawal characteristics of benzodiazepine receptor ligands in different seizure models in mice. II. The novel imidazoquinazolines NNC 14-0185 and NNC 14-0189.
    W Löscher, C Rundfeldt, D Hönack and U Ebert
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 573-581;
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    Monoaminergic substrates underlying cocaine-induced enhancement of somatosensory-evoked discharges in rat barrel field cortical neurons.
    B D Waterhouse, E M Gould and I Bekavac
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 582-592;
  • You have access
    Functional properties of muscarinic receptor subtypes Hm1, Hm3 and Hm5 expressed in Sf9 cells using the baculovirus expression system.
    J P Kukkonen, J Näsman, P Ojala, C Oker-Blom and K E Akerman
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 593-601;
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    Effects of gamma-aminobutyric acid agonists on the isolated perfused rat kidney.
    L A Monasterolo, L Trumper and M M Elías
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 602-607;
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    The role of endogenous opioids in enhancing the antinociception produced by the combination of delta 9-tetrahydrocannabinol and morphine in the spinal cord.
    G Pugh, P B Smith, D S Dombrowski and S P Welch
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 608-616;
  • You have access
    Inhibitory effect of amiodarone on the muscarinic acetylcholine receptor-operated potassium current in guinea pig atrial cells.
    Y Watanabe, Y Hara, M Tamagawa and H Nakaya
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 617-624;
  • You have access
    Transport of paraquat in a renal epithelial cell line LLC-PK1.
    B S Chan, V A Lazzaro, J P Seale and G G Duggin
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 625-632;
  • You have access
    Pharmacological targeting of signaling pathways in protein kinase C-stimulated superoxide generation in neutrophil-like HL-60 cells: effect of phorbol ester, arachidonic acid and inhibitors of kinase(s), phosphatase(s) and phospholipase A2.
    A M Mayer, S Brenic and K B Glaser
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 633-644;
  • You have access
    Antiviral activity and mechanism of action of calanolide A against the human immunodeficiency virus type-1.
    M J Currens, R J Gulakowski, J M Mariner, R A Moran, R W Buckheit, K R Gustafson, J B McMahon and M R Boyd
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 645-651;
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    Kinetic analysis of inhibition of human immunodeficiency virus type-1 reverse transcriptase by calanolide A.
    M J Currens, J M Mariner, J B McMahon and M R Boyd
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 652-661;
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    The substance P amino-terminal metabolite substance P(1-7), administered peripherally, prevents the development of acute morphine tolerance and attenuates the expression of withdrawal in mice.
    J S Kreeger and A A Larson
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 662-667;
  • You have access
    Protein kinase C modulates flow-initiated contraction.
    H Xie, I Laher and J A Bevan
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 668-674;
  • You have access
    Receptor binding and antagonist properties of a novel endothelin receptor antagonist, TAK-044 [cyclo[D-alpha-aspartyl-3-[(4-phenylpiperazin-1-yl) carbonyl]-L-alanyl-L-alpha-aspartyl-D-2-(2-thienyl) glycyl-L-leucyl-D-tryptophyl]disodium salt], in human endothelinA and endothelinB receptors.
    Y Masuda, T Sugo, T Kikuchi, A Kawata, M Satoh, Y Fujisawa, Y Itoh, M Wakimasu and T Ohtaki
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 675-685;
  • You have access
    Reduction of serum lactate by sodium dichloroacetate, and human pharmacokinetic-pharmacodynamic relationships.
    A W Fox, B W Sullivan, J D Buffini, M L Neichin, R Nicora, F K Hoehler, R O'Rourke and R R Stoltz
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 686-693;
  • You have access
    Comparison of ligand binding affinities at human I1-imidazoline binding sites and the high affinity state of alpha-2 adrenoceptor subtypes.
    J E Piletz, H Zhu and D N Chikkala
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 694-702;
  • You have access
    Differential effects of angiotensin converting enzyme inhibitors on the vasodepressor and prostacyclin responses to bradykinin.
    N J Brown, D Ryder, J V Gainer, J D Morrow and J Nadeau
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 703-712;
  • You have access
    Metabolism of cocaine and heroin is catalyzed by the same human liver carboxylesterases.
    L M Kamendulis, M R Brzezinski, E V Pindel, W F Bosron and R A Dean
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 713-717;
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    Secretin inhibits canine gastric acid secretion in response to pentagastrin by modulating gastric histamine release.
    J G Gerber and N A Payne
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 718-723;
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    Imipramine-induced inactivation of a cytochrome P450 2D enzyme in rat liver microsomes: in relation to covalent binding of its reactive intermediate.
    Y Masubuchi, S Igarashi, T Suzuki, T Horie and S Narimatsu
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 724-731;
  • You have access
    Effect of MDL 105,212, a nonpeptide NK-1/NK-2 receptor antagonist in an allergic guinea pig model.
    E M Kudlacz, R W Knippenberg, D E Logan and T P Burkholder
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 732-739;
  • You have access
    L-deprenyl (selegiline) decreases excitatory synaptic transmission in the rat hippocampus via a dopaminergic mechanism.
    K S Hsu, C C Huang, M T Su and J J Tsai
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 740-747;
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    Lubeluzole protects sensorimotor function and reduces infarct size in a photochemical stroke model in rats.
    M De Ryck, R Keersmaekers, H Duytschaever, C Claes, G Clincke, M Janssen and G Van Reet
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 748-758;
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    Lubeluzole, a novel long-term neuroprotectant, inhibits the glutamate-activated nitric oxide synthase pathway.
    A S Lesage, L Peeters and J E Leysen
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 759-766;
  • You have access
    Gender-related differences in the antinociceptive properties of morphine.
    T J Cicero, B Nock and E R Meyer
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 767-773;
  • You have access
    Hepatic uptake of choline in rat liver basolateral and canalicular membrane vesicle preparations.
    Y Kwon, R D Lee and M E Morris
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 774-781;
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    Repeated administration of meta-chlorophenylpiperazine or 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane produces tolerance to its stimulatory effect on adrenocorticotropin hormone but not prolactin or corticosterone secretion in rats.
    P Mazzola-Pomietto, C S Aulakh, S J Huang and D L Murphy
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 782-789;
  • You have access
    Pharmacokinetics of aminoguanidine administration and effects on the diabetes frequency in nonobese diabetic mice.
    M A Bowman, O G Simell, A B Peck, J Cornelius, R Luchetta, Z Look, N K Maclaren and M A Atkinson
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 790-794;
  • You have access
    Participation of AT1 and AT2 receptors in the differential interaction between angiotensin II or III and alpha-2 adrenoceptors in the nucleus reticularis gigantocellularis in cardiovascular regulation and antinociception in rats.
    C H Yang, M H Shyr, P P Tan and S H Chan
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 795-802;
  • You have access
    Pharmacokinetic/pharmacodynamic relationship of benzodiazepines in the direct cortical stimulation model of anticonvulsant effect.
    A Hoogerkamp, R H Arends, A M Bomers, J W Mandema, R A Voskuyl and M Danhof
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 803-812;
  • You have access
    Non-neurogenic electrically evoked relaxation in canine airway muscle involves action of free radicals on K+ channels.
    L J Janssen and J Wattie
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 813-821;
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    The inhibition of ganglionic transmission via presynaptic dopamine DA1 and postsynaptic DA2 receptor activation in the canine cardiac sympathetic ganglia.
    M Mukai, K Kushiku, H Yamada, K Yamada, K Dan and T Furukawa
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 822-829;
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    Superficial sarcoplasmic reticulum calcium buffering of resting, voltage-dependent Ca++ influx in rat femoral arterial smooth muscle.
    Y Nomura, M Asano, K Ito, Y Uyama, Y Imaizumi and M Watanabe
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 830-837;
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    Inhibition by protamine of catecholamine secretion and ion influxes in bovine adrenal medullary cells in culture.
    K Minami, N Yanagihara, K Segawa, T Sata, M Tsutsui, A Shigematsu and F Izumi
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 838-843;
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    Quinidine enhances and suppresses Kv1.2 from outside and inside the cell, respectively.
    G N Tseng, B Zhu, S Ling and J A Yao
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 844-855;
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    Quinidine preferentially blocks the slow delayed rectifier potassium channel in the rested state.
    J A Yao, E J Trybulski and G N Tseng
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 856-864;
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    Reverse use dependence of Kv4.2 blockade by 4-aminopyridine.
    G N Tseng, M Jiang and J A Yao
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 865-876;
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    Effects of the new class I antiarrhythmic agent Ro 22-9194, (2R)-2-amino-N-(2,6-dimethylphenyl)-N-[3-(3-pyridyl)propyl]propionamide D-tartrate, on ischemia- and reperfusion-induced arrhythmias in dogs: involvement of thromboxane A2 synthase inhibitory activity.
    M Murakami, M Kinukawa, T Kanazawa, K Maruyama, M Miyagi, H Miyata and A Ujiie
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 877-883;
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    The central cholinergic system has a role in the antinociception induced in rodents and guinea pigs by the antimigraine drug sumatriptan.
    C Ghelardini, N Galeotti, M Figini, A Imperato, M Nicolodi, F Sicuteri, G L Gessa and A Bartolini
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 884-890;
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    Effects of tetrandrine on spontaneous and evoked release of acetylcholine at the mouse neuromuscular junction.
    H Wiegand, L J McIntosh, U Gotzsch and U Krämer
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 891-901;
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    Organ-specific pattern of inhibition of diltiazem metabolism at steady state in rabbits.
    M Lefebvre, G Caillé and P du Souich
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 902-907;
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    Local deep tissue penetration of compounds after dermal application: structure-tissue penetration relationships.
    P Singh and M S Roberts
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 908-917;
  • You have access
    Lipopolysaccharide inhibits acetylcholine- and nitric oxide-mediated vasodilation in vivo.
    T S Peters and S J Lewis
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 918-925;
  • You have access
    Search for lead structures to develop new allosteric modulators of muscarinic receptors.
    C Tränkle, E Kostenis, U Burgmer and K Mohr
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 926-933;
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    Methoclocinnamox: agonist and antagonist effects of a novel long-lasting opioid in rhesus monkeys.
    E R Butelman, J W Lewis and J H Woods
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 934-938;
  • You have access
    Positron emission tomographic analysis of central 5-hydroxytryptamine2 receptor occupancy in healthy volunteers treated with the novel antipsychotic agent, ziprasidone.
    A J Fischman, A A Bonab, J W Babich, N M Alpert, S L Rauch, D R Elmaleh, T M Shoup, S A Williams and R H Rubin
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 939-947;
  • You have access
    Chronic carvedilol reduces mortality and renal damage in hypertensive stroke-prone rats.
    F C Barone, A H Nelson, E H Ohlstein, R N Willette, J E Sealey, J H Laragh, W G Campbell and G Z Feuerstein
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 948-955;
  • You have access
    Inhibitors of coenzyme A-independent transacylase induce apoptosis in human HL-60 cells.
    J D Winkler, T Eris, C M Sung, M Chabot-Fletcher, R J Mayer, M E Surette and F H Chilton
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 956-966;
  • You have access
    Blockade of alpha-2 adrenergic receptors in the rostral ventrolateral medulla attenuates the sympathoinhibitory response to cocaine.
    T P Abrahams, W Liu and K J Varner
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 967-974;
  • You have access
    The cytoprotective effect of leminoprazole on indomethacin-induced damage to rabbit gastric mucosal cells.
    S Takahashi and S Okabe
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 975-982;
  • You have access
    Molecular effects of M17055, furosemide and thiazide on cardiac hypertrophy of spontaneously hypertensive rats.
    S Kim, A Hamaguchi, T Shinkawa, Y Kato, N Tsuchiya, K Miura, K Ohta and H Iwao
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 983-990;
  • You have access
    Imprinted overinduction of hepatic CYP2B1 and 2B2 in adult rats neonatally exposed to phenobarbital.
    A K Agrawal and B H Shapiro
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 991-999;
  • You have access
    Tissue distribution and complex formation with IgE of an anti-IgE antibody after intravenous administration in cynomolgus monkeys.
    J A Fox, T E Hotaling, C Struble, J Ruppel, D J Bates and M B Schoenhoff
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 1000-1008;
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    Ribavirin potentiates the efficacy and toxicity of 2',3'- dideoxyinosine in the murine acquired immunodeficiency syndrome model.
    P Harvie, R F Omar, N Dusserre, N Lansac, A Désormeaux, P Gourde, M Simard, M Tremblay, D Beauchamp and M G Bergeron
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 1009-1017;
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    Role of membrane potential in the accumulation of quaternized ellipticines by human tumor cell lines.
    D T Vistica, S Kenney, M Hursey and M R Boyd
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 1018-1025;
  • You have access
    Targeting of antibody-conjugated plasminogen activators to the pulmonary vasculature.
    V R Muzykantov, E S Barnathan, E N Atochina, A Kuo, S M Danilov and A B Fisher
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 1026-1034;
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    Chronic fluoxetine induces a gradual desensitization of 5-HT1A receptors: reductions in hypothalamic and midbrain Gi and G(o) proteins and in neuroendocrine responses to a 5-HT1A agonist.
    Q Li, N A Muma and L D van de Kar
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 1035-1042;
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    Neurotoxic and pharmacologic studies on enantiomers of the N-methylated analog of cathinone (methcathinone): a new drug of abuse.
    M Sparago, J Wlos, J Yuan, G Hatzidimitriou, J Tolliver, T A Dal Cason, J Katz and G Ricaurte
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 1043-1052;
  • You have access
    Endothelin receptor coupling to potassium and chloride channels in isolated rat pulmonary arterial myocytes.
    K J Salter and R Z Kozlowski
    Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 1053-1062;
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Journal of Pharmacology and Experimental Therapeutics
Vol. 279, Issue 2
1 Nov 1996
  • Table of Contents
  • Table of Contents (PDF)
  • Index by author
  • Back Matter (PDF)
  • Editorial Board (PDF)
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  • Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.
  • Functional Selectivity and Classical Concepts of Quantitative Pharmacology
  • Abl Protein-Tyrosine Kinase Inhibitor STI571 Inhibits In Vitro Signal Transduction Mediated by c-Kit and Platelet-Derived Growth Factor Receptors
  • The Prediction of Human Pharmacokinetic Parameters from Preclinical and In Vitro Metabolism Data
  • A METHOD FOR DETERMINING LOSS OF PAIN SENSATION
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