Journal of Pharmacology and Experimental Therapeutics: 279 (2)

November 01, 1996; Volume 279,Issue 2

Article

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IN MEMORIAM
Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 443-S;

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Synergistic behavioral interaction between ethanol and clonidine in rats: role of alpha-2 adrenoceptors.
L Mao and A A Abdel-Rahman

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 443-449;
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Effects of transdermal nicotine delivery on measures of acute nicotine withdrawal.
W B Pickworth, R V Fant, M F Butschky and J E Henningfield

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 450-456;
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Pharmacological characterization of inward current evoked by N-methyl-D-aspartate in dopamine neurons in the rat brain slice.
Y N Wu and S W Johnson

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 457-463;
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Mechanical and energetic effects of cromakalim on guinea pig left ventricular papillary muscle.
T Joseph, C Coirault, L Ducros and Y Lecarpentier

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 464-471;
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Anti-interleukin 4 antibody and indomethacin synergistic effect on B16 melanoma tumor progression.
C Blaya, J Crespo, A Crespo and S F Aliño

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 472-477;
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Aging and glucocorticoids: effects on cell signaling mediated through adenylyl cyclase.
T A Slotkin, L Thai, E C McCook, J L Saleh, J Zhang and F J Seidler

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 478-491;
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Anticonvulsant and behavioral profile of L-701,324, a potent, orally active antagonist at the glycine modulatory site on the N-methyl-D-aspartate receptor complex.
L J Bristow, P H Hutson, J J Kulagowski, P D Leeson, S Matheson, F Murray, D Rathbone, K L Saywell, L Thorn, A P Watt and M D Tricklebank

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 492-501;
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Peripheral morphine analgesia: synergy with central sites and a target of morphine tolerance.
Y A Kolesnikov, S Jain, R Wilson and G W Pasternak

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 502-506;
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In vitro biotransformation of dynorphin A (1-17) is similar in human and rhesus monkey blood as studied by matrix-assisted laser desorption/ionization mass spectrometry.
J Yu, E R Butelman, J H Woods, B T Chait and M J Kreek

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 507-514;
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Pharmacological properties of acquired excitotoxicity in Chinese hamster ovary cells transfected with N-methyl-D-aspartate receptor subunits.
F A Boeckman and E Aizenman

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 515-523;
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Effects of naltrexone on response to intravenous cocaine, hydromorphone and their combination in humans.
S L Walsh, J T Sullivan, K L Preston, J E Garner and G E Bigelow

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 524-538;
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N-cyclobutylmethyl analog of normorphinone, N-CBM-TAMO: a short-term opioid agonist and long-term Mu-selective irreversible opioid antagonist.
J Y Xu, A Seyed-Mozaffari, S Archer and J M Bidlack

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 539-547;
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Nephrotoxicity of acetaminophen in male Wistar rats: role of hepatically derived metabolites.
L Trumper, L A Monasterolo and M M Elías

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 548-554;
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Molecular basis and species specificity of high affinity binding of vasoactive intestinal polypeptide by the rat secretin receptor.
M H Holtmann, E M Hadac, C D Ulrich and L J Miller

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 555-560;
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Long-term studies on anticonvulsant tolerance and withdrawal characteristics of benzodiazepine receptor ligands in different seizure models in mice. I. Comparison of diazepam, clonazepam, clobazam and abecarnil.
W Löscher, C Rundfeldt, D Hönack and U Ebert

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 561-572;
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Long-term studies on anticonvulsant tolerance and withdrawal characteristics of benzodiazepine receptor ligands in different seizure models in mice. II. The novel imidazoquinazolines NNC 14-0185 and NNC 14-0189.
W Löscher, C Rundfeldt, D Hönack and U Ebert

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 573-581;
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Monoaminergic substrates underlying cocaine-induced enhancement of somatosensory-evoked discharges in rat barrel field cortical neurons.
B D Waterhouse, E M Gould and I Bekavac

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 582-592;
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Functional properties of muscarinic receptor subtypes Hm1, Hm3 and Hm5 expressed in Sf9 cells using the baculovirus expression system.
J P Kukkonen, J Näsman, P Ojala, C Oker-Blom and K E Akerman

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 593-601;
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Effects of gamma-aminobutyric acid agonists on the isolated perfused rat kidney.
L A Monasterolo, L Trumper and M M Elías

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 602-607;
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The role of endogenous opioids in enhancing the antinociception produced by the combination of delta 9-tetrahydrocannabinol and morphine in the spinal cord.
G Pugh, P B Smith, D S Dombrowski and S P Welch

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 608-616;
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Inhibitory effect of amiodarone on the muscarinic acetylcholine receptor-operated potassium current in guinea pig atrial cells.
Y Watanabe, Y Hara, M Tamagawa and H Nakaya

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 617-624;
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Transport of paraquat in a renal epithelial cell line LLC-PK1.
B S Chan, V A Lazzaro, J P Seale and G G Duggin

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 625-632;
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Pharmacological targeting of signaling pathways in protein kinase C-stimulated superoxide generation in neutrophil-like HL-60 cells: effect of phorbol ester, arachidonic acid and inhibitors of kinase(s), phosphatase(s) and phospholipase A2.
A M Mayer, S Brenic and K B Glaser

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 633-644;
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Antiviral activity and mechanism of action of calanolide A against the human immunodeficiency virus type-1.
M J Currens, R J Gulakowski, J M Mariner, R A Moran, R W Buckheit, K R Gustafson, J B McMahon and M R Boyd

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 645-651;
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Kinetic analysis of inhibition of human immunodeficiency virus type-1 reverse transcriptase by calanolide A.
M J Currens, J M Mariner, J B McMahon and M R Boyd

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 652-661;
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The substance P amino-terminal metabolite substance P(1-7), administered peripherally, prevents the development of acute morphine tolerance and attenuates the expression of withdrawal in mice.
J S Kreeger and A A Larson

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 662-667;
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Protein kinase C modulates flow-initiated contraction.
H Xie, I Laher and J A Bevan

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 668-674;
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Receptor binding and antagonist properties of a novel endothelin receptor antagonist, TAK-044 [cyclo[D-alpha-aspartyl-3-[(4-phenylpiperazin-1-yl) carbonyl]-L-alanyl-L-alpha-aspartyl-D-2-(2-thienyl) glycyl-L-leucyl-D-tryptophyl]disodium salt], in human endothelinA and endothelinB receptors.
Y Masuda, T Sugo, T Kikuchi, A Kawata, M Satoh, Y Fujisawa, Y Itoh, M Wakimasu and T Ohtaki

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 675-685;
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Reduction of serum lactate by sodium dichloroacetate, and human pharmacokinetic-pharmacodynamic relationships.
A W Fox, B W Sullivan, J D Buffini, M L Neichin, R Nicora, F K Hoehler, R O'Rourke and R R Stoltz

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 686-693;
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Comparison of ligand binding affinities at human I1-imidazoline binding sites and the high affinity state of alpha-2 adrenoceptor subtypes.
J E Piletz, H Zhu and D N Chikkala

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 694-702;
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Differential effects of angiotensin converting enzyme inhibitors on the vasodepressor and prostacyclin responses to bradykinin.
N J Brown, D Ryder, J V Gainer, J D Morrow and J Nadeau

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 703-712;
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Metabolism of cocaine and heroin is catalyzed by the same human liver carboxylesterases.
L M Kamendulis, M R Brzezinski, E V Pindel, W F Bosron and R A Dean

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 713-717;
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Secretin inhibits canine gastric acid secretion in response to pentagastrin by modulating gastric histamine release.
J G Gerber and N A Payne

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 718-723;
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Imipramine-induced inactivation of a cytochrome P450 2D enzyme in rat liver microsomes: in relation to covalent binding of its reactive intermediate.
Y Masubuchi, S Igarashi, T Suzuki, T Horie and S Narimatsu

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 724-731;
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Effect of MDL 105,212, a nonpeptide NK-1/NK-2 receptor antagonist in an allergic guinea pig model.
E M Kudlacz, R W Knippenberg, D E Logan and T P Burkholder

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 732-739;
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L-deprenyl (selegiline) decreases excitatory synaptic transmission in the rat hippocampus via a dopaminergic mechanism.
K S Hsu, C C Huang, M T Su and J J Tsai

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 740-747;
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Lubeluzole protects sensorimotor function and reduces infarct size in a photochemical stroke model in rats.
M De Ryck, R Keersmaekers, H Duytschaever, C Claes, G Clincke, M Janssen and G Van Reet

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 748-758;
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Lubeluzole, a novel long-term neuroprotectant, inhibits the glutamate-activated nitric oxide synthase pathway.
A S Lesage, L Peeters and J E Leysen

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 759-766;
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Gender-related differences in the antinociceptive properties of morphine.
T J Cicero, B Nock and E R Meyer

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 767-773;
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Hepatic uptake of choline in rat liver basolateral and canalicular membrane vesicle preparations.
Y Kwon, R D Lee and M E Morris

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 774-781;
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Repeated administration of meta-chlorophenylpiperazine or 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane produces tolerance to its stimulatory effect on adrenocorticotropin hormone but not prolactin or corticosterone secretion in rats.
P Mazzola-Pomietto, C S Aulakh, S J Huang and D L Murphy

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 782-789;
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Pharmacokinetics of aminoguanidine administration and effects on the diabetes frequency in nonobese diabetic mice.
M A Bowman, O G Simell, A B Peck, J Cornelius, R Luchetta, Z Look, N K Maclaren and M A Atkinson

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 790-794;
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Participation of AT1 and AT2 receptors in the differential interaction between angiotensin II or III and alpha-2 adrenoceptors in the nucleus reticularis gigantocellularis in cardiovascular regulation and antinociception in rats.
C H Yang, M H Shyr, P P Tan and S H Chan

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 795-802;
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Pharmacokinetic/pharmacodynamic relationship of benzodiazepines in the direct cortical stimulation model of anticonvulsant effect.
A Hoogerkamp, R H Arends, A M Bomers, J W Mandema, R A Voskuyl and M Danhof

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 803-812;
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Non-neurogenic electrically evoked relaxation in canine airway muscle involves action of free radicals on K+ channels.
L J Janssen and J Wattie

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 813-821;
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The inhibition of ganglionic transmission via presynaptic dopamine DA1 and postsynaptic DA2 receptor activation in the canine cardiac sympathetic ganglia.
M Mukai, K Kushiku, H Yamada, K Yamada, K Dan and T Furukawa

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 822-829;
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Superficial sarcoplasmic reticulum calcium buffering of resting, voltage-dependent Ca++ influx in rat femoral arterial smooth muscle.
Y Nomura, M Asano, K Ito, Y Uyama, Y Imaizumi and M Watanabe

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 830-837;
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Inhibition by protamine of catecholamine secretion and ion influxes in bovine adrenal medullary cells in culture.
K Minami, N Yanagihara, K Segawa, T Sata, M Tsutsui, A Shigematsu and F Izumi

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 838-843;
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Quinidine enhances and suppresses Kv1.2 from outside and inside the cell, respectively.
G N Tseng, B Zhu, S Ling and J A Yao

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 844-855;
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Quinidine preferentially blocks the slow delayed rectifier potassium channel in the rested state.
J A Yao, E J Trybulski and G N Tseng

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 856-864;
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Reverse use dependence of Kv4.2 blockade by 4-aminopyridine.
G N Tseng, M Jiang and J A Yao

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 865-876;
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Effects of the new class I antiarrhythmic agent Ro 22-9194, (2R)-2-amino-N-(2,6-dimethylphenyl)-N-[3-(3-pyridyl)propyl]propionamide D-tartrate, on ischemia- and reperfusion-induced arrhythmias in dogs: involvement of thromboxane A2 synthase inhibitory activity.
M Murakami, M Kinukawa, T Kanazawa, K Maruyama, M Miyagi, H Miyata and A Ujiie

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 877-883;
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The central cholinergic system has a role in the antinociception induced in rodents and guinea pigs by the antimigraine drug sumatriptan.
C Ghelardini, N Galeotti, M Figini, A Imperato, M Nicolodi, F Sicuteri, G L Gessa and A Bartolini

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 884-890;
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Effects of tetrandrine on spontaneous and evoked release of acetylcholine at the mouse neuromuscular junction.
H Wiegand, L J McIntosh, U Gotzsch and U Krämer

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 891-901;
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Organ-specific pattern of inhibition of diltiazem metabolism at steady state in rabbits.
M Lefebvre, G Caillé and P du Souich

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 902-907;
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Local deep tissue penetration of compounds after dermal application: structure-tissue penetration relationships.
P Singh and M S Roberts

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 908-917;
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Lipopolysaccharide inhibits acetylcholine- and nitric oxide-mediated vasodilation in vivo.
T S Peters and S J Lewis

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 918-925;
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Search for lead structures to develop new allosteric modulators of muscarinic receptors.
C Tränkle, E Kostenis, U Burgmer and K Mohr

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 926-933;
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Methoclocinnamox: agonist and antagonist effects of a novel long-lasting opioid in rhesus monkeys.
E R Butelman, J W Lewis and J H Woods

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 934-938;
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Positron emission tomographic analysis of central 5-hydroxytryptamine2 receptor occupancy in healthy volunteers treated with the novel antipsychotic agent, ziprasidone.
A J Fischman, A A Bonab, J W Babich, N M Alpert, S L Rauch, D R Elmaleh, T M Shoup, S A Williams and R H Rubin

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 939-947;
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Chronic carvedilol reduces mortality and renal damage in hypertensive stroke-prone rats.
F C Barone, A H Nelson, E H Ohlstein, R N Willette, J E Sealey, J H Laragh, W G Campbell and G Z Feuerstein

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 948-955;
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Inhibitors of coenzyme A-independent transacylase induce apoptosis in human HL-60 cells.
J D Winkler, T Eris, C M Sung, M Chabot-Fletcher, R J Mayer, M E Surette and F H Chilton

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 956-966;
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Blockade of alpha-2 adrenergic receptors in the rostral ventrolateral medulla attenuates the sympathoinhibitory response to cocaine.
T P Abrahams, W Liu and K J Varner

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 967-974;
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The cytoprotective effect of leminoprazole on indomethacin-induced damage to rabbit gastric mucosal cells.
S Takahashi and S Okabe

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 975-982;
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Molecular effects of M17055, furosemide and thiazide on cardiac hypertrophy of spontaneously hypertensive rats.
S Kim, A Hamaguchi, T Shinkawa, Y Kato, N Tsuchiya, K Miura, K Ohta and H Iwao

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 983-990;
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Imprinted overinduction of hepatic CYP2B1 and 2B2 in adult rats neonatally exposed to phenobarbital.
A K Agrawal and B H Shapiro

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 991-999;
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Tissue distribution and complex formation with IgE of an anti-IgE antibody after intravenous administration in cynomolgus monkeys.
J A Fox, T E Hotaling, C Struble, J Ruppel, D J Bates and M B Schoenhoff

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 1000-1008;
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Ribavirin potentiates the efficacy and toxicity of 2',3'- dideoxyinosine in the murine acquired immunodeficiency syndrome model.
P Harvie, R F Omar, N Dusserre, N Lansac, A Désormeaux, P Gourde, M Simard, M Tremblay, D Beauchamp and M G Bergeron

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 1009-1017;
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Role of membrane potential in the accumulation of quaternized ellipticines by human tumor cell lines.
D T Vistica, S Kenney, M Hursey and M R Boyd

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 1018-1025;
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Targeting of antibody-conjugated plasminogen activators to the pulmonary vasculature.
V R Muzykantov, E S Barnathan, E N Atochina, A Kuo, S M Danilov and A B Fisher

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 1026-1034;
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Chronic fluoxetine induces a gradual desensitization of 5-HT1A receptors: reductions in hypothalamic and midbrain Gi and G(o) proteins and in neuroendocrine responses to a 5-HT1A agonist.
Q Li, N A Muma and L D van de Kar

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 1035-1042;
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Neurotoxic and pharmacologic studies on enantiomers of the N-methylated analog of cathinone (methcathinone): a new drug of abuse.
M Sparago, J Wlos, J Yuan, G Hatzidimitriou, J Tolliver, T A Dal Cason, J Katz and G Ricaurte

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 1043-1052;
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Endothelin receptor coupling to potassium and chloride channels in isolated rat pulmonary arterial myocytes.
K J Salter and R Z Kozlowski

Journal of Pharmacology and Experimental Therapeutics November 1996, 279 (2) 1053-1062;

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