Journal of Pharmacology and Experimental Therapeutics: 278 (1)

July 01, 1996; Volume 278,Issue 1

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Characterization of endothelin-induced nociception in mice: evidence for a mechanistically distinct analgesic model.
R B Raffa, J J Schupsky, D K Lee and H I Jacoby

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 1-7;
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Paracetamol exerts a spinal antinociceptive effect involving an indirect interaction with 5-hydroxytryptamine3 receptors: in vivo and in vitro evidence.
T Pelissier, A Alloui, F Caussade, C Dubray, A Cloarec, J Lavarenne and A Eschalier

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 8-14;
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The sensitivity of N-methyl-D-aspartate receptors to lead inhibition is dependent on the receptor subunit composition.
I A Omelchenko, C S Nelson, J L Marino and C N Allen

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 15-20;
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Identification of human cytochrome P450 isoforms involved in the stereoselective metabolism of mianserin enantiomers.
E Koyama, K Chiba, M Tani and T Ishizaki

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 21-30;
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Stereospecificity in contraluminal and luminal transporters of organic cations in the rat renal proximal tubule.
A A Somogyi, G Rumrich, G Fritzsch and K J Ullrich

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 31-36;
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Inhibition of type IV phosphodiesterase by Ro 20-1724 attenuates endotoxin-induced acute renal failure.
D P Begany, J A Carcillo, W A Herzer, Z Mi and E K Jackson

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 37-41;
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Endothelin A receptor antagonism by PD 156707 does not reduce infarct size after coronary artery occlusion/reperfusion in pigs.
T E Mertz, T B McClanahan, M A Flynn, P Juneau, E E Reynolds, H Hallak, L Bradford and K P Gallagher

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 42-49;
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Effects of drug discrimination history on the generalization of pentobarbital to other drugs.
D E McMillan, W L Sun and W C Hardwick

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 50-61;
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Nonpeptide glycoprotein IIb/IIIa inhibitors. 8. Antiplatelet activity and oral antithrombotic efficacy of L-734,217.
J J Cook, M A Holahan, E A Lyle, D R Ramjit, G R Sitko, M T Stranieri, R F Stupienski, A A Wallace, E L Hand, J R Gehret, T Kothstein, M D Drag, G Y McCormick, J J Perkins, N C Ihle, M E Duggan, G D Hartman, R J Gould and J J Lynch

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 62-73;
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Influence of feeding schedule on the chronopharmacological aspects of sodium valproate in mice.
S Ohdo, N Ogawa, S Nakano and S Higuchi

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 74-81;
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Effect of S-21663 (PMS 812), an imidazoline derivative, on glucose tolerance and insulin secretion in a rat model of type II diabetes.
X Wang, F Rondu, A Lamouri, R Dokhan, S Marc, E Touboul, B Pfeiffer, D Manechez, P Renard, B Guardiola-Lemaitre, J J Godfroid, A Ktorza and L Pénicaud

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 82-89;
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Involvement of spinal cholecystokininB receptors in mediating neurotensin hyperalgesia from the medullary nucleus raphe magnus in the rat.
M O Urban, D J Smith and G F Gebhart

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 90-96;
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Intrathecal nicotinic agonist-elicited release of excitatory amino acids as measured by in vivo spinal microdialysis in rats.
I M Khan, M Marsala, M P Printz, P Taylor and T L Yaksh

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 97-106;
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Poor permeability of morphine 3-glucuronide and morphine 6-glucuronide through the blood-brain barrier in the rat.
U Bickel, O P Schumacher, Y S Kang and K Voigt

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 107-113;
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Evidence for a selective effect of ethanol on N-methyl-d-aspartate responses: ethanol affects a subtype of the ifenprodil-sensitive N-methyl-d-aspartate receptors.
X Yang, H E Criswell, P Simson, S Moy and G R Breese

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 114-124;
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Involvement of alpha-2 adrenoceptors in the periaqueductal gray-induced inhibition of dorsal horn cell activity in rats.
Y B Peng, Q Lin and W D Willis

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 125-135;
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Structure activity relationships of a series of buspirone analogs at alpha-1 adrenoceptors: further evidence that rat aorta alpha-1 adrenoceptors are of the alpha-1D-subtype.
D L Saussy, A S Goetz, K L Queen, H K King, M W Lutz and T J Rimele

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 136-144;
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Modulation of [3H]quinpirole binding in brain by monoamine oxidase inhibitors: evidence for a potential novel binding site.
B Levant, J D Moehlenkamp, K A Morgan, N L Leonard and C C Cheng

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 145-153;
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Comparison of bidisomide, flecainide and dofetilide on action potential duration in isolated canine atria: effect of isoproterenol.
C L Martin, M A Palomo and E G Mcmahon

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 154-162;
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Cytotoxicity of hexachlorocyclohexane isomers and cyclodienes in primary cultures of cerebellar granule cells.
R Rosa, E Rodriguez-Farré and C Sanfeliu

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 163-169;
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Electrophysiologic and proarrhythmogenic effects of therapeutic and toxic doses of imipramine: a study with high resolution ventricular epicardial mapping in rabbit hearts.
E Robert, P Bruelle, J E de La Coussaye, J M Juan, J Brugada, P Peray, M Dauzat and J J Eledjam

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 170-178;
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Evaluation of detomidine-induced analgesia in horses with chronic hoof pain.
J G Owens, S G Kamerling, S R Stanton and M L Keowen

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 179-184;
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The potential of a novel polyamine transport inhibitor in cancer chemotherapy.
S M Aziz, M N Gillespie, P A Crooks, S F Tofiq, C P Tsuboi, J W Olson and M P Gosland

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 185-192;
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Nitric oxide modulates neuropeptide Y regulation of ion transport in mouse ileum.
R K Rao, Y Lopez, P J Riviere, X Pascaud, J L Junien and F Porreca

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 193-198;
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Inhibitory transmission in guinea pig stomach mediated by distinct receptors for pituitary adenylate cyclase-activating peptide.
S Katsoulis, W E Schmidt, R Schwarzhoff, U R Folsch, J G Jin, J R Grider and G M Makhlouf

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 199-204;
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The secretory intestinal transport of some beta-lactam antibiotics and anionic compounds: a mechanism contributing to poor oral absorption.
H Saitoh, C Gerard and B J Aungst

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 205-211;
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Enhancement of morphine antinociception by a CCKB antagonist in mice is mediated via opioid delta receptors.
T W Vanderah, R N Bernstein, H I Yamamura, V J Hruby and F Porreca

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 212-219;
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The effects of calcitonin gene-related peptide on the cytosolic calcium concentration and force in the porcine coronary artery.
Y Fukuizumi, S Kobayashi, J Nishimura and H Kanaide

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 220-231;
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Systemic and regional hemodynamic and biological effects of a new kappa-opioid agonist, niravoline, in healthy volunteers.
E Bellissant, T Denolle, P Sinnassamy, D G Bichet, J F Giudicelli, F Lecoz, J M Gandon and H Allain

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 232-242;
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E2011 a novel, selective and reversible inhibitor of monoamine oxidase type A.
T Kagaya, A Kajiwara, S Nagato, K Akasaka and A Kubota

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 243-251;
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Recombinant human secretory phospholipase A2 released thromboxane from guinea pig bronchoalveolar lavage cells: in vitro and ex vivo evaluation of a novel secretory phospholipase A2 inhibitor.
J H Fleisch, C T Armstrong, C R Roman, E D Mihelich, S M Spaethe, W T Jackson, J L Bobbitt, S Draheim, N J Bach, R D Dillard, M Martinelli, R Fouts and D W Snyder

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 252-257;
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Co-administration of MDMA with drugs that protect against MDMA neurotoxicity produces different effects on body temperature in the rat.
J E Malberg, K E Sabol and L S Seiden

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 258-267;
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U46619 (a thromboxane A2 mimetic) induces airflow obstruction and airway plasma extravasation in the guinea pig: the role of histamine, cyclooxygenase metabolites, leukotrienes and PAF.
I Kawikova, H Arakawa, B E Skoogh, C G Löfdahl and J Lötvall

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 268-276;
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Influence of renal failure in rats on the disposition of salicyl acyl glucuronide and covalent binding of salicylate to plasma proteins.
J H Liu, R S Malone, H Stallings and P C Smith

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 277-283;
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Contrasting effects of anesthetics in tadpole bioassays.
H Downes and P M Courogen

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 284-296;
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Inhibition of the slow pressor effect of angiotensin II contributes to the antihypertensive effect of angiotensin-converting enzyme inhibitors in renovascular hypertension.
M G Melaragno and G D Fink

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 297-303;
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Antinociceptive action of 2-(4-bromobenzoyl)-3-methyl-4,6-dimethoxy benzofuran, a novel xanthoxyline derivative on chemical and thermal models of nociception in mice.
Z R Vaz, V C Filho, R A Yunes and J B Calixto

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 304-312;
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Long-term exposure to ethanol increases the number and function of muscarinic M1 receptors in human neuroblastoma cells.
C Larsson, P Simonsson, M Caron and C Alling

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 313-319;
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U-73122: a potent inhibitor of human polymorphonuclear neutrophil adhesion on biological surfaces and adhesion-related effector functions.
R J Smith, J M Justen, A R McNab, C L Rosenbloom, A N Steele, P A Detmers, D C Anderson and A M Manning

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 320-329;
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Locomotor sensitization and decrease in [3H]mazindol binding to the dopamine transporter in the nucleus accumbens are delayed after chronic treatments by GBR12783 or cocaine.
D Boulay, D Duterte-Boucher, I Leroux-Nicollet, L Naudon and J Costentin

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 330-337;
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Ethanol exposure alters the phosphorylation of cyclic AMP responsive element binding protein and cyclic AMP responsive element binding activity in rat cerebellum.
X Yang, A M Diehl and G S Wand

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 338-346;
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Cocaine-induced sensitization of metabolic activity in extrapyramidal circuits involves prior dopamine D1-like receptor stimulation.
W L Thomas, E S Cooke and R P Hammer

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 347-353;
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Dopamine D2L receptor couples to G alpha i2 and G alpha i3 but not G alpha i1, leading to the inhibition of adenylate cyclase in transfected cell lines.
C M O'Hara, L Tang, R Taussig, R D Todd and K L O'Malley

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 354-360;
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Chronic nicotine and mecamylamine treatment increase brain nicotinic receptor binding without changing alpha 4 or beta 2 mRNA levels.
J R Pauly, M J Marks, S F Robinson, J L van de Kamp and A C Collins

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 361-369;
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Inhibition of prostaglandin synthesis in newborn pigs increases cerebral microvessel prostaglandin F2 alpha and prostaglandin E2 receptors, their second messengers and vasoconstrictor response to adult levels.
D Y Li, D Abran, K G Peri, D R Varma and S Chemtob

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 370-377;
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The thrombin inhibitor, hirudin, attenuates lipopolysaccharide-induced liver injury in the rat.
J M Pearson, A E Schultze, K A Schwartz, M A Scott, J M Davis and R A Roth

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 378-383;
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Repeated intra-ventral tegmental area administration of SKF-38393 induces behavioral and neurochemical sensitization to a subsequent cocaine challenge.
R C Pierce, B Born, M Adams and P W Kalivas

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 384-392;
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To what extent do spinal interactions between an alpha-2 adrenoceptor agonist and a mu opioid agonist influence noxiously evoked c-Fos expression in the rat? A pharmacological study.
P Honoré, V Chapman, J Buritova and J M Besson

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 393-403;
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Chronic intrathecal infusion of phosphorothioate or phosphodiester antisense oligonucleotides against cytokine responsive gene-2/IP-10 in experimental allergic encephalomyelitis of lewis rat.
W J Wojcik, P Swoveland, X Zhang and P Vanguri

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 404-410;
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Evidence for involvement of ventral tegmental area cyclic AMP systems in behavioral sensitization to psychostimulants.
B K Tolliver, L B Ho, M S Reid and S P Berger

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 411-420;
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Enhanced release of interleukin-10 and soluble tumor necrosis factor receptors as novel principles of methylxanthine action in murine models of endotoxic shock.
S Jilg, J Barsig, M Leist, S Küsters, H D Volk and A Wendel

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 421-431;
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Conformationally biased analogs of human C5a mediate changes in vascular permeability.
R Kawatsu, S D Sanderson, I Blanco, N Kendall, A M Finch, S M Taylor and D Colcher

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 432-440;
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Frequent distribution of ultrarapid metabolizers of debrisoquine in an ethiopian population carrying duplicated and multiduplicated functional CYP2D6 alleles.
E Aklillu, I Persson, L Bertilsson, I Johansson, F Rodrigues and M Ingelman-Sundberg

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 441-446;
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An antisense oligodeoxynucleotide to glyceraldehyde-3-phosphate dehydrogenase blocks age-induced apoptosis of mature cerebrocortical neurons in culture.
R Ishitani, M Kimura, K Sunaga, N Katsube, M Tanaka and D M Chuang

Journal of Pharmacology and Experimental Therapeutics July 1996, 278 (1) 447-454;

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