Journal of Pharmacology and Experimental Therapeutics: 276 (2)

February 01, 1996; Volume 276,Issue 2

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Inhibition of cerebral neurogenic vasodilation by L-glutamine and nitric oxide synthase inhibitors and its reversal by L-citrulline.
T J Lee, S Sarwinski, T Ishine, C C Lai and F Y Chen

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 353-358;
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I2-imidazoline binding sites: relationship with different monoamine oxidase domains and identification of histidine residues mediating ligand binding regulation by H+1.
I Limon-Boulez, F Tesson, C Gargalidis-Moudanos and A Parini

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 359-364;
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Activation of cyclic AMP-dependent protein kinase reverses tolerance of a nucleoside transporter to ethanol.
I R Coe, D P Dohrman, A Constantinescu, I Diamond and A S Gordon

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 365-369;
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Triazolam biotransformation by human liver microsomes in vitro: effects of metabolic inhibitors and clinical confirmation of a predicted interaction with ketoconazole.
L L von Moltke, D J Greenblatt, J S Harmatz, S X Duan, L M Harrel, M M Cotreau-Bibbo, G A Pritchard, C E Wright and R I Shader

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 370-379;
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BMS-180448, a novel glyburide-reversible cardioprotective agent, enhances postischemic recovery of contractile function in dogs.
G J Grover, C S Parham, D B Whigan and J G Mitroka

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 380-387;
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Pharmacological characterization of in vivo properties of putative mixed 5-HT1A agonist/5-HT2A/2C antagonist anxiolytics. I. Antipunishment effects in the pigeon.
M S Kleven and W Koek

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 388-397;
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The non-xanthine heterocyclic compound SCH 58261 is a new potent and selective A2a adenosine receptor antagonist.
C Zocchi, E Ongini, A Conti, A Monopoli, A Negretti, P G Baraldi and S Dionisotti

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 398-404;
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The quaternary transformation products of N-(3-chloropropyl)-4-piperidinyl diphenylacetate and N-(2-chloroethyl)-4-piperidinyl diphenylacetate (4-DAMP mustard) have differential affinity for subtypes of the muscarinic receptor.
F J Ehlert, H S Oliff and M T Griffin

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 405-410;
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Role of imidazoline receptors in the cardiovascular actions of moxonidine, rilmenidine and clonidine in conscious rabbits.
C K Chan, F Sannajust and G A Head

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 411-420;
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Oral biological activities of spontaneous nitric oxide releasers are accounted for by their nitric oxide-releasing rates and oral absorption manners.
Y Kita, Y Hirasawa, S Fukuyama, K Ohkubo, Y Kato, H Takamatsu, M Ohno, S Nishino, M Kato and J Seki

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 421-425;
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Effects of somatostatin and related peptides on the membrane potential and input resistance of rat ventral subicular neurons, in vitro.
J R Greene and A Mason

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 426-432;
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Calcium sensitization in perfused beating guinea pig heart by a positive inotropic agent MCI-154.
Y Abe, R Ishisu, K Onishi, K Sekioka, A Narimatsu and T Nakano

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 433-439;
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Relative analgesic potency of mu, delta and kappa opioids after spinal administration in amphibians.
C W Stevens

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 440-448;
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Buprenorphine's physical dependence potential: antagonist-precipitated withdrawal in humans.
T Eissenberg, M K Greenwald, R E Johnson, I A Liebson, G E Bigelow and M L Stitzer

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 449-459;
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The role of nitric oxide in dizocilpine-induced impairment of spontaneous alternation behavior in mice.
K Yamada, Y Noda, T Hasegawa, Y Komori, T Nikai, H Sugihara and T Nabeshima

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 460-466;
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Selective inhibition by a class III antiarrhythmic agent, E-4031, of the negative chronotropic response to parasympathetic stimulation in anesthetized dogs.
H Imamura, Y Furukawa, H Nakano, M Kasama, Y Hoyano and S Chiba

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 467-472;
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Pharmacological characterization of A-127722: an orally active and highly potent ETA-selective receptor antagonist.
T J Opgenorth, A L Adler, S V Calzadilla, W J Chiou, B D Dayton, D B Dixon, L J Gehrke, L Hernandez, S R Magnuson, K C Marsh, E I Novosad, T W Von Geldern, J L Wessale, M Winn and J R Wu-Wong

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 473-481;
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Nicotine-induced inhibition in medial septum involves activation of presynaptic nicotinic cholinergic receptors on gamma-aminobutyric acid-containing neurons.
X Yang, H E Criswell and G R Breese

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 482-489;
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Characterization of 8-(N-methylisopropyl)amino-N6-(5'-endohydroxy- endonorbornyl)-9-methyladenine (WRC-0571), a highly potent and selective, non-xanthine antagonist of A1 adenosine receptors.
P L Martin, R J Wysocki, R J Barrett, J M May and J Linden

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 490-499;
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Characterization of the antinociceptive properties of cimetidine and a structural analog.
B Y Li, J W Nalwalk, L A Barker, P Cumming, M E Parsons and L B Hough

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 500-508;
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Epibatidine: a nicotinic acetylcholine receptor agonist releases monoaminergic neurotransmitters: in vitro and in vivo evidence in rats.
A I Sacaan, F Menzaghi, J L Dunlop, L D Correa, K T Whelan and G K Lloyd

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 509-515;
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Modulation of seizure activity in mice by metabotropic glutamate receptor ligands.
N O Dalby and C Thomsen

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 516-522;
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Discriminative stimulus effects of nalbuphine in rhesus monkeys.
L R Gerak and C P France

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 523-531;
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Differential genetic mediation of sensitivity to morphine in genetic models of opiate antinociception: influence of nociceptive assay.
J S Mogil, B Kest, B Sadowski and J K Belknap

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 532-544;
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kappa-Opioid receptor agonists prevent sensitization to the conditioned rewarding effects of cocaine.
T S Shippenberg, A LeFevour and C Heidbreder

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 545-554;
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Effects of lipid A on calcium homeostasis in renal proximal tubules.
J W Proksch, L A Traylor and P R Mayeux

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 555-560;
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Mechanisms for the hepatic uptake and biliary excretion of tributylmethylammonium: studies with rat liver plasma membrane vesicles.
R H Moseley, H Smit, B G Van Solkema, W Wang and D K Meijer

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 561-567;
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Cocaine concentration-effect relationship in the presence and absence of lidocaine: evidence of competitive binding between cocaine and lidocaine.
D Liu, R J Hariman and J L Bauman

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 568-577;
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Glucocorticoid interactions with ethanol effects on synaptic plasma membranes: influence on [125I]calmodulin binding.
P Y Sze

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 578-584;
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Investigation of brain sites mediating cannabinoid-induced antinociception in rats: evidence supporting periaqueductal gray involvement.
A H Lichtman, S A Cook and B R Martin

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 585-593;
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A three-lever operant procedure differentiates the stimulus effects of R(-)-MDA from S(+)-MDA.
R Young and R A Glennon

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 594-601;
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Effect of lipid-free total parenteral nutrition on hepatic drug conjugation in rats.
R B Raftogianis, M R Franklin and R E Galinsky

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 602-608;
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Nonpeptide endothelin receptor antagonists. VI: Pharmacological characterization of SB 217242, a potent and highly bioavailable endothelin receptor antagonist.
E H Ohlstein, P Nambi, A Lago, D W Hay, G Beck, K L Fong, E P Eddy, P Smith, H Ellens and J D Elliott

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 609-615;
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Cooperative contributions of cholinergic and NMDA receptors in the presynaptic control of dopamine release from synaptosomes of the rat striatum.
A Chéramy, G Godeheu, M L'Hirondel and J Glowinski

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 616-625;
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Assessment of the involvement of central nervous system and peripheral opioid receptors in the immunomodulatory effects of acute morphine treatment in rats.
K Fecho, K A Maslonek, L A Dykstra and D T Lysle

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 626-636;
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Combined potassium and calcium channel blocking activities as a basis for antiarrhythmic efficacy with low proarrhythmic risk: experimental profile of BRL-32872.
A Bril, B Gout, M Bonhomme, L Landais, J F Faivre, P Linee, R H Poyser and R R Ruffolo

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 637-646;
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Endothelin-induced nociception in mice: mediation by ETA and ETB receptors.
R B Raffa, J J Schupsky and H I Jacoby

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 647-651;
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Estradiol increases cyclic adenosine monophosphate in rat pulmonary vascular smooth muscle cells by a nongenomic mechanism.
M Y Farhat, S Abi-Younes, B Dingaan, R Vargas and P W Ramwell

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 652-657;
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Identification of the human cytochromes P450 responsible for the in vitro formation of the major oxidative metabolites of the antipsychotic agent olanzapine.
B J Ring, J Catlow, T J Lindsay, T Gillespie, L K Roskos, B J Cerimele, S P Swanson, M A Hamman and S A Wrighton

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 658-666;
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Low level hyperbaric antagonism of diazepam's locomotor depressant and anticonvulsant properties in mice.
D L Davies, M Bejanian, E S Parker, J Mørland, M B Bolger, R D Brinton and R L Alkana

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 667-675;
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Saturable disposition of taurine in the rat cerebrospinal fluid.
S J Chung, V K Ramanathan, C M Brett and K M Giacomini

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 676-682;
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Urine acidification affects the activity of the organic base transporter in a nonstereoselective manner.
M R Ujhelyi, M B Bottorff, M Schur, K Roll, H Zhang, J Stewart and M L Markel

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 683-689;
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A G protein, not cyclic AMP, mediates effects of VIP on the inwardly rectifying K+ channels in endothelial cells.
E A Pasyk, S Cipris and E E Daniel

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 690-696;
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Regulation of 5-hydroxytryptamine release from rat midbrain raphe nuclei by 5-hydroxytryptamine1D receptors: effect of tetrodotoxin, G protein inactivation and long-term antidepressant administration.
G Piñeyro and P Blier

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 697-707;
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Determinants of in vivo activity of neutral endopeptidase 3.4.24.11 and angiotensin converting enzyme inhibitors.
A A Seymour, M M Asaad, B E Abboa-Offei, P L Smith, W L Rogers and C R Dorso

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 708-713;
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Somatostatin inhibits bombesin-stimulated Gi-protein via its own receptor in rabbit colonic smooth muscle cells.
K N Bitar, S Kothary and P C Kothary

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 714-719;
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Pharmacologic characterization of the human 5-hydroxytryptamine2B receptor: evidence for species differences.
D B Wainscott, V L Lucaites, J D Kursar, M Baez and D L Nelson

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 720-727;
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Effects of metabolites of leukotriene B4 on human neutrophil migration and cytosolic calcium levels.
W S Powell, J Rokach, S P Khanapure, S Manna, M Hashefi, S Gravel, R J Macleod, J R Falck and R K Bhatt

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 728-736;
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Noncompetitive NMDA channel blockade during waking intensely stimulates NREM delta.
I G Campbell and I Feinberg

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 737-742;
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Dexamethasone selective inhibition of acute opioid physical dependence in isolated tissues.
A Capasso, A Di Giannuario, A Loizzo, S Pieretti, S Sagratella and L Sorrentino

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 743-751;
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Erythro-9-(2-hydroxy-3-nonyl)adenine inhibits cyclic-3',5'-guanosine monophosphate-stimulated phosphodiesterase to reverse hypoxic pulmonary vasoconstriction in the perfused rat lung.
J Haynes, D W Killilea, P D Peterson and W J Thompson

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 752-757;
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Three-day exposure to low-dose ethanol alters guanine nucleotide binding protein expression in the developing rat hippocampus.
M I Davis-Cox, T L Fletcher, J N Turner, D Szarowski and W Shain

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 758-764;
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Arbutin: mechanism of its depigmenting action in human melanocyte culture.
K Maeda and M Fukuda

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 765-769;
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Galactose-modified streptavidin-GC4 antifibrin monoclonal antibody conjugates: application for two-step thrombus/embolus imaging.
S F Rosebrough and M Hashmi

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 770-775;
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Cannabinoid receptor proteins are increased in Jurkat, human T-cell line after mitogen activation.
Y Daaka, H Friedman and T W Klein

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 776-783;
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Differential coupling of rat D2 dopamine receptor isoforms expressed in Spodoptera frugiperda insect cells.
V A Boundy, L Lu and P B Molinoff

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 784-794;
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Effects of single and short-term administration of clonidine on hypothalamic-pituitary somatotropic function of the adult male rat: an in situ hybridization study.
V De Gennaro Colonna, M Zoli, B P Settembrini, S Ciceri, A De Marco, S G Cella, L F Agnati and E E Muller

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 795-800;
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Differential contribution of descending controls to the antinociceptive actions of kappa and mu opioids: an analysis of formalin-evoked C-fos expression.
K R Gogas, J D Levine and A I Basbaum

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 801-809;
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Prolonged beta adrenoceptor stimulation up-regulates cAMP phosphodiesterase activity in human monocytes by increasing mRNA and protein for phosphodiesterases 4A and 4B.
C D Manning, M M McLaughlin, G P Livi, L B Cieslinski, T J Torphy and M S Barnette

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 810-818;
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Pharmacological and immunological characterization of N-methyl-D-aspartate receptors in human NT2-N neurons.
M Munir, L Lu, Y H Wang, J Luo, B B Wolfe and P McGonigle

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 819-828;
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Homologous desensitization of thromboxane A2 receptor in 1321N1 human astrocytoma cells.
K Sakai, N Nakahata, H Ono, T Yamamoto and Y Ohizumi

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 829-836;
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Sustained activation of phospholipase D via adenosine A3 receptors is associated with enhancement of antigen- and Ca(2+)-ionophore-induced secretion in a rat mast cell line.
H Ali, O H Choi, P F Fraundorfer, K Yamada, H M Gonzaga and M A Beaven

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 837-845;
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Methylenedioxymethamphetamine-induced serotonin deficits are followed by partial recovery over a 52-week period. Part I: Synaptosomal uptake and tissue concentrations.
K E Sabol, R Lew, J B Richards, G L Vosmer and L S Seiden

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 846-854;
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Methylenedioxymethamphetamine-induced serotonin deficits are followed by partial recovery over a 52-week period. Part II: Radioligand binding and autoradiography studies.
R Lew, K E Sabol, C Chou, G L Vosmer, J Richards and L S Seiden

Journal of Pharmacology and Experimental Therapeutics February 1996, 276 (2) 855-865;

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