Journal of Pharmacology and Experimental Therapeutics: 275 (3)

December 01, 1995; Volume 275,Issue 3

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The caffeine- and ryanodine-sensitive Ca++ store in porcine myometrial cells: its heterogeneity of all-or-none Ca++ release.
R Zhuge and W H Hsu

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1077-1083;
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Endothelin ETA and ETB receptors facilitating parasympathetic neurotransmission in the rabbit trachea.
T Yoneyama, M Hori, T Tanaka, Y Matsuda and H Karaki

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1084-1089;
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Effects of chronic haloperidol on reaction time and errors in a sustained attention task: partial reversal by anticholinergics and by amphetamine.
B J Brockel and S C Fowler

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1090-1098;
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H3-receptor activation inhibits cholinergic stimulation of acid secretion in isolated rabbit fundic glands.
A Bado, J P Laigneau, L Moizo, Y Cherifi and M J Lewin

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1099-1103;
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Methamphetamine-induced hyperthermia and dopaminergic neurotoxicity in mice: pharmacological profile of protective and nonprotective agents.
D S Albers and P K Sonsalla

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1104-1114;
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Diabetes and ATP-sensitive potassium channel openers and blockers in isolated ischemic/reperfused hearts.
A Tosaki, D T Engelman, R M Engelman and D K Das

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1115-1123;
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Relative vulnerability of dopamine and GABA neurons in mesencephalic culture to inhibition of succinate dehydrogenase by malonate and 3-nitropropionic acid and protection by NMDA receptor blockade.
G D Zeevalk, E Derr-Yellin and W J Nicklas

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1124-1130;
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Effect of fluoxetine, norfluoxetine, sertraline and desmethyl sertraline on human CYP3A catalyzed 1'-hydroxy midazolam formation in vitro.
B J Ring, S N Binkley, L Roskos and S A Wrighton

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1131-1135;
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Effect of a new aminopeptidase P inhibitor, apstatin, on bradykinin degradation in the rat lung.
M M Prechel, A T Orawski, L L Maggiora and W H Simmons

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1136-1142;
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Endothelin subtypes: effect on isolated rhesus monkey ciliary muscle.
C Millar, J F Poyer, B T Gabelt and P L Kaufman

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1143-1147;
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Ischemic preconditioning, adenosine and bethanechol protect spontaneously hypertensive isolated rat hearts.
A Boutros and J Wang

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1148-1156;
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Intervessel (arteries and veins) and heart/vessel selectivities of therapeutically used calcium entry blockers: variable, vessel-dependent indexes.
M Magnon, P Gallix and I Cavero

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1157-1166;
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1,3-Dipropyl-8-[2-(5,6-epoxy)norbornyl]xanthine, a potent, specific and selective A1 adenosine receptor antagonist in the guinea pig heart and brain and in DDT1MF-2 cells.
L Belardinelli, J C Shryock, Y Zhang, P J Scammells, R Olsson, D Dennis, P Milner, J Pfister and S P Baker

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1167-1176;
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Accumulation of protein-coated liposomes in an extravascular site: influence of increasing carrier circulation lifetimes.
S A Longman, P G Tardi, M J Parr, L Choi, P R Cullis and M B Bally

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1177-1184;
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Pharmacodynamic model for acute tolerance development to the electroencephalographic effects of alfentanil in the rat.
J W Mandema and D R Wada

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1185-1194;
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Striatal dopamine receptors and adenylyl cyclase activity in a rat model of alcohol addiction: effects of ethanol and lisuride treatment.
T May, U Wolf and J Wolffgramm

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1195-1203;
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Suppression by mycophenolate mofetil of the neointimal thickening caused by vascular injury in a rat arterial stenosis model.
E B Fraser-Smith, J D Rosete and R C Schatzman

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1204-1208;
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Pharmacology of 5-chloro-7-trifluoromethyl-1,4-dihydro-2,3-quinoxalinedione: a novel systemically active ionotropic glutamate receptor antagonist.
R M Woodward, J E Huettner, M Tran, J Guastella, J F Keana and E Weber

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1209-1218;
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Hypoxic relaxation in functionally intact cattle coronary artery segments involves K+ ATP channels.
S Kalsner

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1219-1226;
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A metalloporphyrin superoxide dismutase mimetic protects against paraquat-induced endothelial cell injury, in vitro.
B J Day, S Shawen, S I Liochev and J D Crapo

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1227-1232;
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Pharmacological evaluation of selected, orally active, peptidyl inhibitors of human neutrophil elastase.
M J Janusz, S L Durham, C M Hare, J L Geary, A K Mandagere, J C Poole, T N Thompson, D Xu, M R Anagelastro and J P Burkhart

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1233-1238;
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Nafadotride, a potent preferential dopamine D3 receptor antagonist, activates locomotion in rodents.
F Sautel, N Griffon, P Sokoloff, J C Schwartz, C Launay, P Simon, J Costentin, A Schoenfelder, F Garrido and A Mann

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1239-1246;
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Vasorelaxing effect of S-nitrosocaptopril on dog coronary arteries: no cross-tolerance with nitroglycerin.
T Matsumoto, M Takahashi, I Nakae and M Kinoshita

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1247-1253;
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Growth inhibitory effects on human colon adenocarcinoma-derived Caco-2 cells and calcemic potential of 1 alpha,25-dihydroxyvitamin D3 analogs: structure-function relationships.
M G Bischof, K Redlich, C Schiller, M V Chirayath, M Uskokovic, M Peterlik and H S Cross

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1254-1260;
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Pharmacological evaluation of 1229U91, a novel high-affinity and selective neuropeptide Y-Y1 receptor antagonist.
S S Hegde, D W Bonhaus, W Stanley, R M Eglen, T M Moy, M Loeb, S G Shetty, A DeSouza and J Krstenansky

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1261-1266;
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Discriminative stimulus effects of R-(+)-3-amino-1-hydroxypyrrolid-2-one, [(+)-HA-966], a partial agonist of the strychnine-insensitive modulatory site of the N-methyl-D-aspartate receptor.
J M Witkin, S Brave, D French and B Geter-Douglass

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1267-1273;
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Pharmacology of a constitutively active muscarinic receptor generated by random mutagenesis.
T A Spalding, E S Burstein, H Brauner-Osborne, D Hill-Eubanks and M R Brann

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1274-1279;
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Prostaglandins mediate the stimulatory effects of endothelin-1 on cAMP accumulation and inositol-1,4,5-trisphosphate production and contraction in cat iris sphincter.
S Y Yousufzai, Z Ye and A A Abdel-Latif

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1280-1287;
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Stimulation of opioid mu-receptors potentiates beta adrenoceptor-mediated relaxation of canine airway smooth muscle.
E Tagaya, J Tamaoki, A Chiyotani and K Konno

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1288-1292;
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Cholecystokinin octapeptide reverses mu-opioid-receptor-mediated inhibition of calcium current in rat dorsal root ganglion neurons.
N J Liu, T Xu, C Xu, C Q Li, Y X Yu, H G Kang and J S Han

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1293-1299;
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Pharmacological role and degradation processes of neuromedin N in the gastrointestinal tract: an in vitro and in vivo study.
H Barelli, Z Woskowska, S Cipris, J E Fox-Threlkeld, E E Daniel, J P Vincent and F Checler

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1300-1307;
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Methylmercury acts at multiple sites to block hippocampal synaptic transmission.
Y Yuan and W D Atchison

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1308-1316;
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L(+)- and D(-)-lactate modulate rat renal tubular accumulation of amantadine in the presence and absence of bicarbonate.
M R Escobar, K Goralski and D S Sitar

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1317-1323;
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Hemodynamic effects of acute and chronic treatment with aladotril, a mixed inhibitor of neutral endopeptidase and angiotensin I-converting enzyme, in conscious rats with myocardial infarction.
C Marie, C Mossiat, J M Lecomte, J C Schwartz and J Bralet

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1324-1331;
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Characterization of 5-lipoxygenase inhibitors in biochemical and functional in vivo assays.
W G Smith, A F Shaffer, J L Currie, J M Thompson, S Kim, T Rao and P C Isakson

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1332-1338;
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Regulation of morphine antiallodynic efficacy by cholecystokinin in a model of neuropathic pain in rats.
M L Nichols, D Bian, M H Ossipov, J Lai and F Porreca

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1339-1345;
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Antinociceptive effects of cocaine/opioid combinations in rhesus monkeys.
M B Gatch, S S Negus, E R Butelman and N K Mello

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1346-1354;
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Neurochemical and functional characterization of the preferentially selective dopamine D3 agonist PD 128907.
T A Pugsley, M D Davis, H C Akunne, R G MacKenzie, Y H Shih, G Damsma, H Wikstrom, S Z Whetzel, L M Georgic and L W Cooke

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1355-1366;
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The reinforcing effects of dopamine D1 receptor agonists in rhesus monkeys.
M R Weed and W L Woolverton

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1367-1374;
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Short-term drug effects on the signal-averaged electrocardiogram in healthy men: assessment of intra- and interindividual variability of spectral temporal mapping and time-domain analysis.
M Wolzt, L Schmetterer, J Kastner, K Krejcy, G Zanaschka, C Unfried and H G Eichler

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1375-1381;
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BIII 277 CL is a potent and specific ion-channel blocker of the NMDA receptor-channel complex.
A J Carter, W D Bechtel, M Grauert, P Harrison, H Merz and W Stransky

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1382-1389;
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U-89843A is a novel allosteric modulator of gamma-aminobutyric acidA receptors.
H K Im, W B Im, J F Pregenzer, D B Carter and B J Hamilton

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1390-1395;
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Stimulatory effect of leminoprazole on secretion and synthesis of mucus by rabbit gastric mucosal cells.
S Takahashi, E Nakamura and S Okabe

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1396-1401;
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Selective block of tetramethrin-modified sodium channels by (+/-)-alpha-tocopherol (vitamin E).
J H Song and T Narahashi

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1402-1411;
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Influence of the estrus cycle on the discrimination of apparent neuroactive steroid site subtypes on the gamma-aminobutyric acidA receptor complex in the rat.
L D McCauley and K W Gee

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1412-1417;
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The "calcium antagonist" TMB-8 [3,4,5-trimethoxybenzoic acid 8-(diethylamino)octyl ester] is a potent, non-competitive, functional antagonist at diverse nicotinic acetylcholine receptor subtypes.
M Bencherif, C M Eisenhour, R J Prince, P M Lippiello and R J Lukas

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1418-1426;
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Intestinal absorption of calcium in vivo is dependent on endogenous nitric oxide.
R Schleiffer, M Galluser and F Raul

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1427-1432;
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Comparison between the effects of a novel Ca++ sensitizer and a phosphodiesterase inhibitor on stunned myocardium.
B Korbmacher, U Sunderdiek, H D Schulte, G Arnold and J D Schipke

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1433-1441;
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Effects of chronic pentobarbital treatment on the GABAA receptor complex in mammalian cortical neurons.
R Yu and M K Ticku

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1442-1446;
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Tenidap, an anti-inflammatory agent, discharges intracellular Ca++ store and inhibits Ca++ influx in cultured human gingival fibroblasts.
A Fujii, H Matsumoto, T Hashimoto and Y Akimoto

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1447-1452;
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Differential effects of 2,4-dithiobiuret on the synthesis and release of acetylcholine and dopamine from rat pheochromocytoma (PC12) cells.
L M Ireland, C H Yan, L M Nelson and W D Atchison

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1453-1462;
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The metabolic formation of reactive intermediates from clozapine, a drug associated with agranulocytosis in man.
J L Maggs, D Williams, M Pirmohamed and B K Park

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1463-1475;
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Clozapine is oxidized by activated human neutrophils to a reactive nitrenium ion that irreversibly binds to the cells.
Z C Liu and J P Uetrecht

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1476-1483;
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Mouse strain differences in immunosuppression by opioids in vitro.
T K Eisenstein, J J Meissler, T J Rogers, E B Geller and M W Adler

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1484-1489;
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Potential risk of myopathy by HMG-CoA reductase inhibitors: a comparison of pravastatin and simvastatin effects on membrane electrical properties of rat skeletal muscle fibers.
S Pierno, A De Luca, D Tricarico, A Roselli, F Natuzzi, E Ferrannini, M Laico and D C Camerino

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1490-1496;
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Thromboxane synthase inhibitors suppress more effectively the aggregation of thromboxane receptor-desensitized than that of normal platelets: role of adenylylcyclase up-regulation.
R Vezza, G G Nenci and P Gresele

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1497-1505;
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Acetaminophen does not decrease hepatic 3'-phosphoadenosine 5'-phosphosulfate in mice.
H J Kim, P Rozman and C D Klaassen

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1506-1511;
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Role of Kupffer cells in reperfusion injury in fat-loaded livers from ethanol-treated rats.
Z Zhong, H D Connor, R P Mason, W Qu, W Gao, J J Lemasters and R G Thurman

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1512-1517;
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Pharmacology of L-754,142, a highly potent, orally active, nonpeptidyl endothelin antagonist.
D L Williams, K L Murphy, N A Nolan, J A O'Brien, D J Pettibone, S D Kivlighn, S M Krause, E V Lis, G J Zingaro and R A Gabel

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1518-1526;
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Potent and selective inactivation of human liver microsomal cytochrome P-450 isoforms by L-754,394, an investigational human immune deficiency virus protease inhibitor.
M Chiba, J A Nishime and J H Lin

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1527-1534;
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Opioid antinociception in a rat model of visceral pain: systemic versus local drug administration.
R M Craft, S R Henley, R C Haaseth, V J Hruby and F Porreca

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1535-1542;
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Angiotensin II tachyphylaxis in the guinea pig ileum and its prevention: a pharmacological and biochemical study.
C A Kanashiro, T B Paiva, A C Paiva, R N Prioste, J Aboulafia and S I Shimuta

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1543-1550;
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Serotonergic modulation of the behavioral effects of cocaine in the squirrel monkey.
L L Howell and L D Byrd

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1551-1559;
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Participation of delta opioid receptor subtypes in the stimulation of adenylyl cyclase activity in rat olfactory bulb.
M C Olianas and P Onali

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1560-1567;
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Effects of propofol on nociceptive response and power spectra of electroencephalographic and systemic arterial pressure signals in the rat: correlation with plasma concentration.
C H Yang, M H Shyr, T B Kuo, P P Tan and S H Chan

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1568-1574;
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Evidence for dissimilar mechanisms of enhancement of inorganic and organic hydroperoxide cytotoxicity by L-histidine.
A Guidarelli, P Sestili, A Cossarizza, C Franceschi, F Cattabeni and O Cantoni

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1575-1582;
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The specific contribution of the novel alpha-1D adrenoceptor to the contraction of vascular smooth muscle.
M T Piascik, R D Guarino, M S Smith, E E Soltis, D L Saussy and D M Perez

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1583-1589;
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In vivo injection of antisense oligodeoxynucleotides to G alpha subunits and supraspinal analgesia evoked by mu and delta opioid agonists.
P Sánchez-Blázquez, A García-España and J Garzón

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1590-1596;
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Development of delta-opioid receptor subtypes and the regulatory role of weaning: radioligand binding, autoradiography and in situ hybridization studies.
I Kitchen, F M Leslie, M Kelly, R Barnes, T J Crook, R G Hill, A Borsodi, G Toth, P Melchiorri and L Negri

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1597-1607;
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Inhibition of the rat cytochrome P450 3A2 by an antisense phosphorothioate oligodeoxynucleotide in vivo.
J P Desjardins and P L Iversen

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1608-1613;
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Inactivation and degradation of human cytochrome P4502E1 by CCl4 in a transfected HepG2 cell line.
Y Dai and A I Cederbaum

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1614-1622;
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Cloning and pharmacological characterization of the rabbit bradykinin B2 receptor.
D R Bachvarov, E Saint-Jacques, J F Larrivée, L Levesque, F Rioux, G Drapeau and F Marceau

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1623-1630;
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Cloning and characterization of a rat H+/peptide cotransporter mediating absorption of beta-lactam antibiotics in the intestine and kidney.
H Saito, M Okuda, T Terada, S Sasaki and K Inui

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1631-1637;
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5-Hydroxytryptamine2A (5-HT2A) receptor desensitization can occur without down-regulation.
B L Roth, E P Palvimaki, S Berry, N Khan, N Sachs, A Uluer and M S Choudhary

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1638-1646;
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Distribution of 1,3-bis(2-chloroethyl)-1-nitrosourea and tracers in the rabbit brain after interstitial delivery by biodegradable polymer implants.
J F Strasser, L K Fung, S Eller, S A Grossman and W M Saltzman

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1647-1655;
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The expression of alpha 1 adrenoceptor subtypes changes with age in the rat aorta.
H Gurdal, N Tilakaratne, R D Brown, M Fonseca, E Friedman and M D Johnson

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1656-1662;
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Long-term stimulation of nicotinic receptors is required to increase proenkephalin A mRNA levels and the delayed secretion of [Met5]-enkephalin in bovine adrenal medullary chromaffin cells.
H W Suh, P M Hudson, M K McMillian, K P Das, B C Wilson, G C Wu and J S Hong

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1663-1670;
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Pharmacological studies of the regulation of chronic FOS-related antigen induction by cocaine in the striatum and nucleus accumbens.
H E Nye, B T Hope, M B Kelz, M Iadarola and E J Nestler

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1671-1680;
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Metallothionein expression and resistance to cisplatin in a human germ cell tumor cell line.
J Koropatnick, D M Kloth, S Kadhim, J L Chin and M G Cherian

Journal of Pharmacology and Experimental Therapeutics December 1995, 275 (3) 1681-1687;

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