Journal of Pharmacology and Experimental Therapeutics: 275 (2)

November 01, 1995; Volume 275,Issue 2

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Effects of putative cannabinoid receptor ligands, anandamide and 2-arachidonyl-glycerol, on immune function in B6C3F1 mouse splenocytes.
M Lee, K H Yang and N E Kaminski

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 529-536;
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Disposition characteristics of recombinant human interleukin-11 after a bolus intravenous administration in mice.
A Takagi, H Masuda, Y Takakura and M Hashida

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 537-543;
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Sensitization to the behavioral effect of kainic acid in the mouse is mediated by nitric oxide.
A A Larson and K F Kitto

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 544-550;
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Nitric oxide mediation of cocaine-induced dopaminergic behaviors: ambulation-accelerating activity, reverse tolerance and conditioned place preference in mice.
H S Kim and W K Park

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 551-557;
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Supra-additive natriuretic synergism between bendroflumethiazide and furosemide in rats.
T E Jonassen, L Grønbeck, M Shalmi, J S Petersen, F Andreasen and S Christensen

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 558-565;
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Variability in human cytochrome P450 paclitaxel metabolism.
D S Sonnichsen, Q Liu, E G Schuetz, J D Schuetz, A Pappo and M V Relling

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 566-575;
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Serotonin stimulates rapid increase of inositol 1,4,5-trisphosphate in ovine uterine artery: correlation with contractile state.
L Zhang and X Q Hu

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 576-583;
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HP-228, a novel synthetic peptide, inhibits the induction of nitric oxide synthase in vivo but not in vitro.
G Abou-Mohamed, A Papapetropoulos, D Ulrich, J D Catravas, R R Tuttle and R W Caldwell

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 584-591;
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N-demethylation of amitriptyline in vitro: role of cytochrome P-450 3A (CYP3A) isoforms and effect of metabolic inhibitors.
J Schmider, D J Greenblatt, L L von Moltke, J S Harmatz and R I Shader

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 592-597;
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Pharmacological characterization of GT-2016, a non-thiourea-containing histamine H3 receptor antagonist: in vitro and in vivo studies.
C E Tedford, S L Yates, G P Pawlowski, J W Nalwalk, L B Hough, M A Khan, J G Phillips, G J Durant and R C Frederickson

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 598-604;
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Factors affecting serum protein binding of cocaine in humans.
R B Parker, C L Williams, S C Laizure and J J Lima

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 605-610;
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Effects of a selective DP receptor agonist (BW 245C) and antagonist (BW A868C) on the canine colonic epithelium: an argument for a different DP receptor?
P K Rangachari, P A Betti, E T Prior and L J Roberts

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 611-617;
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Antinociceptive effects of R(-)- and S(+)-flurbiprofen on rat spinal dorsal horn neurons rendered hyperexcitable by an acute knee joint inflammation.
V Neugebauer, G Geisslinger, P Rümenapp, F Weiretter, I Szelenyi, K Brune and H G Schaible

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 618-628;
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Effects of intrathecal and intracerebroventricular buprenorphine on a C-fiber reflex in the rat.
F Guirimand, M Chauvin, J C Willer and D Le Bars

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 629-637;
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Allosteric interactions at L-type calcium channels between FPL 64176 and the enantiomers of the dihydropyridine Bay K 8644.
M M Usowicz, M Gigg, L M Jones, C W Cheung and S A Hartley

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 638-645;
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Cardiovascular responses to cigarette smoke exposure in restrained conscious rats.
A A Houdi, R T Dowell and J N Diana

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 646-653;
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Depletion of hepatic 3'-phosphoadenosine 5'-phosphosulfate (PAPS) and sulfate in rats by xenobiotics that are sulfated.
H J Kim, J H Cho and C D Klaassen

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 654-658;
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Coronary and hemodynamic effects of S 16257, a new bradycardic agent, in resting and exercising conscious dogs.
L Simon, B Ghaleh, L Puybasset, J F Giudicelli and A Berdeaux

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 659-666;
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Different effects of indomethacin and nabumetone on prostaglandin-mediated gastric responses to central vagal activation in rats.
S Cardin, A H Soll and Y Taché

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 667-673;
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Role of second messengers in agonist up-regulation of 5-HT2A (5-HT2) receptor binding sites in cerebellar granule neurons: involvement of calcium influx and a calmodulin-dependent pathway.
H Chen, H Li and D M Chuang

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 674-680;
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Pinacidil relaxes porcine and human coronary arteries by activating ATP-dependent potassium channels in smooth muscle cells.
M Gollasch, R Bychkov, C Ried, F Behrendt, S Scholze, F C Luft and H Haller

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 681-692;
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Anticonvulsant tolerance and withdrawal characteristics of benzodiazepine receptor ligands in different seizure models in mice. Comparison of diazepam, bretazenil and abecarnil.
C Rundfeldt, P Wlaź, D Hönack and W Löscher

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 693-702;
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Inhibition of lipopolysaccharide-induced pulmonary edema by isozyme-selective phosphodiesterase inhibitors in guinea pigs.
R E Howell, L P Jenkins and D E Howell

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 703-709;
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Prostaglandin E2 contracts vascular smooth muscle and inhibits potassium currents in vascular smooth muscle cells of rat tail artery.
J Ren, E Karpinski and C G Benishin

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 710-719;
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Galanin receptors in human basal forebrain differ from receptors in the hypothalamus: characterization using [125I]galanin (porcine) and [125I]galantide.
D C Deecher, O O Odusan and E J Mufson

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 720-727;
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Effects of (-)-S-2,8-dimethyl-3-methylene-1-oxa-8-azaspiro[4,5]decane L-tartrate monohydrate (YM796), a novel muscarinic agonist, on disturbance of passive avoidance learning behavior in drug-treated and senescence-accelerated mice.
M Suzuki, T Yamaguchi, Y Ozawa, M Ohyama and M Yamamoto

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 728-736;
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Pharmacological characterization of LY303870: a novel, potent and selective nonpeptide substance P (neurokinin-1) receptor antagonist.
B D Gitter, R F Bruns, J J Howbert, D C Waters, P G Threlkeld, L M Cox, J A Nixon, K L Lobb, N R Mason and P W Stengel

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 737-744;
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Cardiovascular effects of the novel dual inhibitor of neutral endopeptidase and angiotensin-converting enzyme BMS-182657 in experimental hypertension and heart failure.
N C Trippodo, J A Robl, M M Asaad, J E Bird, B C Panchal, T R Schaeffer, M Fox, M R Giancarli and H S Cheung

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 745-752;
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NMDA antagonist properties of the putative antiaddictive drug, ibogaine.
P Popik, R T Layer, L H Fossom, M Benveniste, B Geter-Douglass, J M Witkin and P Skolnick

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 753-760;
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U-90042, a sedative/hypnotic compound that interacts differentially with the GABAA receptor subtypes.
A H Tang, M W Smith, D B Carter, W B Im and P F VonVoigtlander

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 761-767;
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Effect of oleanolic acid on hepatic toxicant-activating and detoxifying systems in mice.
J Liu, Y Liu, A Parkinson and C D Klaassen

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 768-774;
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Increased function of voltage-dependent Ca++ channels and Ca(++)-activated K+ channels in resting state of femoral arteries from spontaneously hypertensive rats at prehypertensive stage.
M Asano, Y Nomura, K Ito, Y Uyama, Y Imaizumi and M Watanabe

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 775-783;
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Chronic neurosteroid treatment decreases the efficacy of benzodiazepine ligands and neurosteroids at the gamma-aminobutyric acidA receptor complex in mammalian cortical neurons.
R Yu and M K Ticku

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 784-789;
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Critical role for glucocorticoid receptors in stress- and ethanol-induced locomotor sensitization.
A J Roberts, C N Lessov and T J Phillips

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 790-797;
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EUK-8, a synthetic superoxide dismutase and catalase mimetic, ameliorates acute lung injury in endotoxemic swine.
P K Gonzalez, J Zhuang, S R Doctrow, B Malfroy, P F Benson, M J Menconi and M P Fink

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 798-806;
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KR-30450, a newly synthesized benzopyran derivative, activates the cardiac ATP-sensitive K+ channel.
Y G Kwak, S K Park, H S Kang, J S Kim, S W Chae, K P Cho, S E Yoo and D Kim

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 807-812;
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Effects of photodegradation products of nifedipine: the nitroso-derivative relaxes contractions of the rat aortic strip induced by norepinephrine and other agonists.
N Hayase, S Inagaki and Y Abiko

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 813-821;
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A drug discrimination analysis of the actions of novel serotonin1A receptor ligands in the rat using the 5-HT1A receptor agonist, 8-hydroxy-2-(di-n-propylamino)tetralin.
R Schreiber, M Brocco, B Lefèbvre de Ladonchamps, S Monneyron and M J Millan

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 822-831;
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Plasma digoxin immunoreactivity and arterial potassium relaxation after quinapril therapy in hypertensive rats.
M Kähönen, P A Doris, H Mäkynen and I Pörsti

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 832-837;
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Muscarine induces an anomalous inhibition of synaptic transmission in rat auditory thalamic neurons in vitro.
D M Mooney, B Hu and V V Senatorov

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 838-844;
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(+)-N-allylnormetazocine enhances N-acetyltransferase activity and melatonin synthesis: preliminary evidence for a functional role of sigma receptors in the rat pineal gland.
L Steardo, P Monteleone, M d'Istria, I Serino, M Maj and V Cuomo

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 845-849;
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Effects of methylprednisolone and 21-aminosteroids on mitogen-induced interleukin-6 and tumor necrosis factor-alpha production in human peripheral blood mononuclear cells.
F Buttgereit, I Brink, B Thiele, G R Burmester, F Hiepe and E D Hall

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 850-853;
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Moexipril, a new angiotensin-converting enzyme (ACE) inhibitor: pharmacological characterization and comparison with enalapril.
O Edling, G Bao, M Feelisch, T Unger and P Gohlke

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 854-863;
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Closed- and open-state binding of 4-aminopyridine to the cloned human potassium channel Kv1.5.
R Bouchard and D Fedida

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 864-876;
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Regulation of striatal cyclic-3',5'-adenosine monophosphate accumulation and GABA release by glutamate metabotropic and dopamine D1 receptors.
J Wang and K M Johnson

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 877-884;
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Functional correlates of dopamine D3 receptor activation in the rat in vivo and their modulation by the selective antagonist, (+)-S 14297: 1. Activation of postsynaptic D3 receptors mediates hypothermia, whereas blockade of D2 receptors elicits prolactin secretion and catalepsy.
M J Millan, J L Peglion, J Vian, J M Rivet, M Brocco, A Gobert, A Newman-Tancredi, C Dacquet, K Bervoets and S Girardon

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 885-898;
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Functional correlates of dopamine D3 receptor activation in the rat in vivo and their modulation by the selective antagonist, (+)-S 14297: II. Both D2 and "silent" D3 autoreceptors control synthesis and release in mesolimbic, mesocortical and nigrostriatal pathways.
A Gobert, J M Rivet, V Audinot, L Cistarelli, M Spedding, J Vian, J L Peglion and M J Millan

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 899-913;
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Telemetry monitoring of hemodynamic effects induced over time by adenosine agonists in spontaneously hypertensive rats.
C Casati, A Monopoli, A Forlani, E Bonizzoni and E Ongini

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 914-919;
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Toxicodynamic analysis of cough and inflammatory reactions by angiotensin-converting enzyme inhibitors in guinea pig.
K Ito, K Ito, Y Sawada, J Kamei, M Misawa and T Iga

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 920-925;
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Peritubular paraquat transport in isolated renal proximal tubules.
C E Groves, M N Morales, A J Gandolfi, W H Dantzler and S H Wright

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 926-932;
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Membrane permeability and lipophilicity in the isolated perfused rat liver: 5-ethyl barbituric acid and other compounds.
C Chou, A J McLachlan and M Rowland

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 933-940;
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Pretreatment with a blocking monoclonal antibody to P-selectin accelerates pharmacological thrombolysis in a primate model of arterial thrombosis.
C F Toombs, G L DeGraaf, J P Martin, J G Geng, D C Anderson and R J Shebuski

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 941-949;
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Mechanisms of ethanol-induced suppression of a primary antibody response in a mouse model for binge drinking.
Y C Han and S B Pruett

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 950-957;
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Mechanisms of absorption enhancement by medium chain fatty acids in intestinal epithelial Caco-2 cell monolayers.
T Lindmark, T Nikkilä and P Artursson

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 958-964;
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Tissue distribution of cocaine methyl esterase and ethyl transferase activities: correlation with carboxylesterase protein.
R A Dean, J Zhang, M R Brzezinski and W F Bosron

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 965-971;
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Age- and sex-related alterations of microsomal drug- and testosterone-oxidizing cytochrome P450 in Sprague-Dawley strain-derived dwarf rats.
M Shimada, N Murayama, Y Yamazoe, H Hashimoto, H Ishikawa and R Kato

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 972-977;
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Characterization of alpha 2 adrenoceptors and other adrenoceptors in membranes isolated from dog mesenteric nerve axons.
E E Daniel, V Gaspar, I Berezin and C Y Kwan

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 978-986;
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Mechanisms of up-regulation of neuronal nicotinic acetylcholine receptors in clonal cell lines and primary cultures of fetal rat brain.
M Bencherif, K Fowler, R J Lukas and P M Lippiello

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 987-994;
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Anti-inflammatory properties of Gö 6850: a selective inhibitor of protein kinase C.
P B Jacobson, S L Kuchera, A Metz, C Schächtele, K Imre and D J Schrier

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 995-1002;
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Anti-dopamine beta-hydroxylase immunotoxin-induced sympathectomy in adult rats.
M J Picklo, R G Wiley, S Lonce, D A Lappi and D Robertson

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 1003-1010;
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Interindividual variation in expression of P-glycoprotein in normal human liver and secondary hepatic neoplasms.
E G Schuetz, K N Furuya and J D Schuetz

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 1011-1018;
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Amphetamine produces sensitized increases in locomotion and extracellular dopamine preferentially in the nucleus accumbens shell of rats administered repeated cocaine.
R C Pierce and P W Kalivas

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 1019-1029;
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[3H]epibatidine labels nicotinic receptors in rat brain: an autoradiographic study.
D C Perry and K J Kellar

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 1030-1034;
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Quantification of steady state expression of mRNA for alpha-1 adrenergic receptor subtypes using reverse transcription and a competitive polymerase chain reaction.
M A Scofield, F Liu, P W Abel and W B Jeffries

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 1035-1042;
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The immunosuppressant leflunomide inhibits lymphocyte proliferation by inhibiting pyrimidine biosynthesis.
H M Cherwinski, R G Cohn, P Cheung, D J Webster, Y Z Xu, J P Caulfield, J M Young, G Nakano and J T Ransom

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 1043-1049;
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Neurochemical and behavioral evidence that quipazine-ketanserin discrimination is mediated by serotonin2A receptor.
R L Smith, R J Barrett and E Sanders-Bush

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 1050-1057;
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Cyclopiazonic acid, inhibiting the endoplasmic reticulum calcium pump, reduces the canine colonic pacemaker frequency.
L W Liu, L Thuneberg and J D Huizinga

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 1058-1068;
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Reye syndrome model in rats: protection against liver abnormalities by L-carnitine and acetyl-L-carnitine.
M Visentin, R Bellasio and M T Tacconi

Journal of Pharmacology and Experimental Therapeutics November 1995, 275 (2) 1069-1075;

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