Journal of Pharmacology and Experimental Therapeutics: 272 (3)

March 01, 1995; Volume 272,Issue 3

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Pharmacologic characterization of CI-996, a new angiotensin receptor antagonist.
J A Keiser, M J Ryan, R L Panek, J C Hodges and I Sircar

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 963-969;
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The kappa opioid receptor expressed on the mouse R1.1 thymoma cell line down-regulates without desensitizing during chronic opioid exposure.
D B Joseph and J M Bidlack

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 970-976;
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Homologous desensitization of 5-hydroxytryptamine4 receptors in rat esophagus: functional and second messenger studies.
P Rondé, H Ansanay, A Dumuis, R Miller and J Bockaert

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 977-983;
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Metabolism and bioactivation of clozapine by human liver in vitro.
M Pirmohamed, D Williams, S Madden, E Templeton and B K Park

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 984-990;
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Airway smooth muscle relaxant effects of the cocaine pyrolysis product, methylecgonidine.
H A el-Fawal and R W Wood

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 991-996;
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Modulation of relaxant responses evoked by a nitric oxide donor and by nonadrenergic, noncholinergic stimulation by isozyme-selective phosphodiesterase inhibitors in guinea pig trachea.
J L Ellis and N D Conanan

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 997-1004;
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Ring and link requirements for tocainide binding to the class I antiarrhythmic drug receptor on rat cardiac myocytes.
R S Sheldon and E Thakore

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 1005-1010;
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Lipopolysaccharide-induced changes in plasma nitrite and nitrate concentrations in rats and mice: pharmacological evaluation of nitric oxide synthase inhibitors.
W R Tracey, J Tse and G Carter

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 1011-1015;
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Methylmercury mobilizes Ca++ from intracellular stores sensitive to inositol 1,4,5-trisphosphate in NG108-15 cells.
M F Hare and W D Atchison

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 1016-1023;
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Homologous desensitization of the A1-adenosine receptor system in the guinea pig atrioventricular node.
D M Dennis, J C Shryock and L Belardinelli

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 1024-1035;
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Atrial natriuretic peptide modulates sodium and potassium-activated adenosine triphosphatase through a mechanism involving cyclic GMP and cyclic GMP-dependent protein kinase.
C Scavone, C Scanlon, M McKee and J A Nathanson

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 1036-1043;
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Modulation of norepinephrine release by serotonergic receptors in the rat hippocampus as measured by in vivo microdialysis.
M Matsumoto, M Yoshioka, H Togashi, M Tochihara, T Ikeda and H Saito

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 1044-1051;
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Endothelin-1-evoked calcium transients in UMR-106 osteoblastic osteosarcoma cells are mediated through endothelin-A and endothelin-B receptors.
D E Semler, E H Ohlstein, P Nambi, C Slater and P H Stern

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 1052-1058;
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The acute effects of cocaine on anterior pituitary hormones in ovariectomized rhesus monkeys.
N K Mello, Z Sarnyai, J H Mendelson, J M Drieze and M Kelly

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 1059-1066;
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Behavioral and electroencephalographic properties of duloxetine (LY248686), a reuptake inhibitor of norepinephrine and serotonin, in mice and rats.
A Katoh, M Eigyo, C Ishibashi, Y Naitoh, M Takeuchi, N Ibii, M Ikeda and A Matsushita

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 1067-1075;
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Human hepatic cytochrome P450 2C9 catalyzes the rate-limiting pathway of torsemide metabolism.
J O Miners, D L Rees, L Valente, M E Veronese and D J Birkett

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 1076-1081;
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Activity of cyclic pseudopeptide antagonists at peripheral tachykinin receptors.
R Patacchini, L Quartara, M Astolfi, C Goso, A Giachetti and C A Maggi

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 1082-1087;
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Coexisting beta-1 and beta-2-adrenergic receptors with differential receptor reserves in rat C6 glioma cells.
H Zhong and K P Minneman

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 1088-1094;
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Effects of cyclopiazonic acid on rat myocardium: inhibition of calcium uptake into sarcoplasmic reticulum.
S Takahashi, Y Kato, M Adachi, N Agata, H Tanaka and K Shigenobu

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 1095-1100;
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Antagonist properties of polyamines and bis(ethyl)polyamines at N-methyl-D-aspartate receptors.
K Igarashi and K Williams

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 1101-1109;
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Increased production of inositol phosphates and diacylglycerol in aged cognitively impaired rats after stimulation of muscarinic, metabotropic-glutamate and endothelin receptors.
A Parent, W Rowe, M J Meaney and R Quirion

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 1110-1116;
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Effects of specific antibody Fab fragments on desipramine pharmacokinetics in the rat in vivo and in the isolated, perfused liver.
D E Keyler, D G Le Couteur, S M Pond, J V St Peter and P R Pentel

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 1117-1123;
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BMS-182874 is a selective, nonpeptide endothelin ETA receptor antagonist.
M L Webb, J E Bird, E C Liu, P M Rose, R Serafino, P D Stein and S Moreland

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 1124-1134;
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Alkylation of mu opioid receptors by beta-funaltrexamine in vivo: comparison of the effects on in situ binding and heroin self-administration in rats.
T J Martin, S I Dworkin and J E Smith

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 1135-1140;
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Nitric oxide synthase inhibitor and lipopolysaccharide effects on reactivity of guinea pig airways.
J S Fedan, T E Warner, L X Yuan, V a Robinson and D G Frazer

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 1141-1150;
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Serotonin uptake and its modulation in rat jejunal enterocyte preparation.
S Takayanagi, H Hanai, J Kumagai and E Kaneko

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 1151-1159;
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Preclinical pharmacological actions of (+/-)-(1'R*,3R*)-3-phenyl-1- [1',2',3',4'-tetrahydro-5',6'-methylene-dioxy-1'-naphthalenyl) methyl] pyrrolidine methanesulfonate (ABT-200), a potential antidepressant agent that antagonizes alpha-2 adrenergic receptors and inhibits the neuronal uptake of norepinephrine.
A A Hancock, S A Buckner, W J Giardina, M E Brune, J Y Lee, P A Morse, K W Oheim, D S Stanisic, R B Warner and D J Kerkman

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 1160-1169;
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Effect of 5-HT1A receptor agonists and antagonists on canine cataplexy.
S Nishino, J Shelton, A Renaud, W C Dement and E Mignot

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 1170-1175;
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Novel 2-substituted cocaine analogs: uptake and ligand binding studies at dopamine, serotonin and norepinephrine transport sites in the rat brain.
B A Bennett, C H Wichems, C K Hollingsworth, H M Davies, C Thornley, T Sexton and S R Childers

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 1176-1186;
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In vivo renal production and tubular secretion of tyramine.
J W Van Huysse, D P Henry and L R Willis

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 1187-1192;
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Differences in purinoceptor modulation of norepinephrine release between caudal arteries of normotensive and hypertensive rats.
K Shinozuka, M Kunitomo, K Hattori, R A Bjur and D P Westfall

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 1193-1198;
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Characterization of the electrophysiological, biochemical and behavioral actions of epibatidine.
D W Bonhaus, K R Bley, C A Broka, D J Fontana, E Leung, R Lewis, A Shieh and E H Wong

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 1199-1203;
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Nonpeptide endothelin receptor antagonists: IV. Identification of receptors in rabbit colonic mucosa and smooth muscle and correlation with physiological effects.
P L Smith, C P Lee, M Pullen, E H Ohlstein, G Beck, E P Eddy and P Nambi

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 1204-1210;
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Human recombinant hemoglobin (rHb1.1) inhibits nonadrenergic noncholinergic (NANC) nerve-mediated relaxation of internal anal sphincter.
S Rattan, G J Rosenthal and S Chakder

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 1211-1216;
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Brain, liver and blood distribution kinetics of carbamazepine and its metabolic interaction with clomipramine in rats: a quantitative microdialysis study.
K Van Belle, S Sarre, G Ebinger and Y Michotte

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 1217-1222;
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Arterial function after trichlormethiazide therapy in spontaneously hypertensive rats.
M Kähönen, H Mäkynen, P Arvola, H Wuorela and I Pörsti

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 1223-1230;
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Mechanism of ketoconazole-induced elevation of individual serum bile acids in the rat: relationship to the effect of ketoconazole on bile acid uptake by isolated hepatocytes.
S A Azer, V Kukongviriyapan and N H Stacey

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 1231-1237;
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Characterization of bronchodilator effects and fate of S-nitrosothiols in the isolated perfused and ventilated guinea pig lung.
G Bannenberg, J Xue, L Engman, I Cotgreave, P Moldéus and A Ryrfeldt

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 1238-1245;
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Mechanisms of morphine-induced immunosuppression: effect of acute morphine administration on lymphocyte trafficking.
L R Flores, S M Wahl and B M Bayer

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 1246-1251;
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Longitudinal and cross-sectional analysis of raloxifene effects on tibiae from ovariectomized aged rats.
M Sato, J Kim, L L Short, C W Slemenda and H U Bryant

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 1252-1259;
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Electrophysiological demonstration of mu, delta and kappa opioid receptors in the ventral pallidum.
I Mitrovic and T C Napier

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 1260-1270;
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Peripheral effects of naloxone in mice with acute diarrhea associated with intestinal inflammation.
O Pol, E Planas and M M Puig

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 1271-1276;
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Methylmercury-thiol uptake into cultured brain capillary endothelial cells on amino acid system L.
E M Mokrzan, L E Kerper, N Ballatori and T W Clarkson

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 1277-1284;
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Messenger RNAs for neurokinin and histamine receptor subtypes in isolated canine colonic crypts.
I Khan, N Lapierre and P K Rangachari

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 1285-1292;
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Tissue-specific expression of flavin-containing monooxygenase (FMO) forms 1 and 2 in the rabbit.
S E Shehin-Johnson, D E Williams, S Larsen-Su, D M Stresser and R N Hines

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 1293-1299;
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4-Methylcatechol, an inducer of nerve growth factor synthesis, enhances peripheral nerve regeneration across nerve gaps.
K Kaechi, R Ikegami, N Nakamura, M Nakajima, Y Furukawa and S Furukawa

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 1300-1304;
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The identity of immunosuppressive components of the ethyl acetate extract and chloroform methanol extract (T2) of Tripterygium wilfordii Hook. F.
X Tao, J J Cai and P E Lipsky

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 1305-1312;
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Differential regulation of human monocyte-derived TNF alpha and IL-1 beta by type IV cAMP-phosphodiesterase (cAMP-PDE) inhibitors.
M W Verghese, R T McConnell, A B Strickland, R C Gooding, S A Stimpson, D P Yarnall, J D Taylor and P J Furdon

Journal of Pharmacology and Experimental Therapeutics March 1995, 272 (3) 1313-1320;

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