Journal of Pharmacology and Experimental Therapeutics: 271 (1)

October 01, 1994; Volume 271,Issue 1

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The mycotoxin ochratoxin-A impairs protein uptake in cells derived from the proximal tubule of the kidney (opossum kidney cells).
M Gekle, S Mildenberger, R Freudinger and S Silbernagl

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 1-6;
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Substance P activates rat colonic motility via excitatory and inhibitory neural pathways and direct action on muscles.
U Scheurer, E Drack and F Halter

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 7-13;
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Glibenclamide reduces the coronary vasoactivity of adenosine receptor agonists.
K Niiya, S Uchida, T Tsuji and R A Olsson

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 14-19;
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Protective effect of ebselen on constrictive hepatic vasculature: prevention of alcohol-induced effects on portal pressure in perfused livers.
M Oshita, Y Takei, S Kawano, H Fusamoto and T Kamada

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 20-24;
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Non-N-methyl-D-aspartate receptor antagonism by 3-N-substituted 2,3-benzodiazepines: relationship to anticonvulsant activity.
S D Donevan, S Yamaguchi and M A Rogawski

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 25-29;
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The dihydropyridine nitrendipine reduces N-methyl-D-aspartate (NMDA)-evoked currents of rodent cortical neurons through a direct interaction with the NMDA receptor-associated ion channel.
G A Skeen, H S White and R E Twyman

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 30-38;
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NK1 receptors mediated release of 6-keto-PGF1 alpha from the ex vivo perfused canine ileum.
M B Parrish, K D Rainsford, D M Johnson and E E Daniel

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 39-47;
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Drug discrimination assessment of agonist-antagonist opioids in humans: a three-choice saline-hydromorphone-butorphanol procedure.
K L Preston and G E Bigelow

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 48-60;
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Neuropeptide Y inhibition of nicotinic receptor-mediated chromaffin cell secretion.
T D Hexum, J Zheng and J Zhu

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 61-66;
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Magnesium and zinc potentiate ethanol inhibition of N-methyl-D-aspartate-stimulated nitric oxide synthase in cortical neurons.
L J Chandler, N J Guzman, C Sumners and F T Crews

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 67-75;
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Inflammation-induced release of excitatory amino acids is prevented by spinal administration of a GABAA but not by a GABAB receptor antagonist in rats.
K A Sluka, W D Willis and K N Westlund

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 76-82;
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Serotonin-dopamine interaction in the rat ventral tegmental area: an electrophysiological study in vivo.
S Prisco, S Pagannone and E Esposito

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 83-90;
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In vitro N-glucuronidation of SB 47436 (BMS 186295), a new AT1 nonpeptide angiotensin II receptor antagonist, by rat, monkey and human hepatic microsomal fractions.
L Perrier, M Bourrié, E Marti, C Tronquet, D Massé, Y Berger, J Magdalou and G Fabre

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 91-99;
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A mechanism of 5-HT3 receptor mediation is involved etiologically in the psychological stress lesion the stomach of the mouse.
K Nomura, N Maeda, T Yoshino and I Yamaguchi

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 100-106;
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Dual effects of nordidemnin on WRK1 cells: inhibition of phosphoinositide metabolism and cell proliferation.
C Dominice, M N Dufour, N Patino, O Manzoni, E Grazzini, P Jouin and G Guillon

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 107-117;
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Diffusion of morphine-6-beta-D-glucuronide into the neonatal guinea pig brain during drug-induced respiratory depression.
L J Murphey and G D Olsen

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 118-124;
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Sensitivity to nicotine and brain nicotinic receptors are altered by chronic nicotine and mecamylamine infusion.
A C Collins, Y Luo, S Selvaag and M J Marks

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 125-133;
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Humanized monoclonal antibody DREG-200 directed against I-selectin protects in feline myocardial reperfusion injury.
M Buerke, A S Weyrich, T Murohara, C Queen, C K Klingbeil, M S Co and A M Lefer

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 134-142;
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Role of various 5-HT receptor subtypes in mediating neuroendocrine effects of 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane (DOM) in rats.
C S Aulakh, P Mazzola-Pomietto, J L Hill and D L Murphy

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 143-148;
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Pharmacological coupling and functional role for the muscarinic receptor subtypes in isolated cells from the circular smooth muscle of the rabbit cecum.
P Cuq, R Magous and J P Bali

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 149-155;
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Analysis of the role of endothelin-A and endothelin-B receptors on nociceptive information transmission in the spinal cord with FR139317, an endothelin-A receptor antagonist, and sarafotoxin S6c, an endothelin-B receptor agonist.
T Yamamoto, N Shimoyama, H Asano and T Mizuguchi

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 156-163;
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The estrus cycle, sensitivity to convulsants and the anticonvulsant effect of a neuroactive steroid.
D A Finn and K W Gee

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 164-170;
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Potentiation of cardiovascular responses to hydralazine by diverse hydrazine derivatives.
H Vidrio

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 171-175;
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Influence of dietary fat on the pharmacodynamics of quinidine, procainamide and tocainide in isolated perfused rabbit hearts.
A M Gillis, M Choi, H J Mathison and H G Parsons

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 176-183;
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Pro- and antiarrhythmic effects of d-sotalol and dl-sotalol in an isolated tissue model of ischemia and reperfusion.
J S Pasnani and G R Ferrier

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 184-192;
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Different combinations of retinoids and vitamin D3 analogs efficiently promote growth inhibition and differentiation of myelomonocytic leukemia cell lines.
H Defacque, J Dornand, T Commes, S Cabane, C Sevilla and J Marti

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 193-199;
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Establishing benzodiazepines as oral reinforcers: midazolam and diazepam self-administration in rhesus monkeys.
R B Stewart, G A Lemaire, J D Roache and R A Meisch

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 200-211;
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Regulation of [3H]dopamine release from rat striatal slices by sigma receptor ligands.
G M Gonzalez-Alvear and L L Werling

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 212-219;
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Ionization and adsorption of a series of local anesthetics in detergent micelles: studies of drug fluorescence.
S Desai, T Hadlock, C Messam, R Chafetz and G Strichartz

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 220-228;
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The bradykinin analog RMP-7 increases intracellular free calcium levels in rat brain microvascular endothelial cells.
S R Doctrow, S M Abelleira, L A Curry, R Heller-Harrison, J W Kozarich, B Malfroy, L A McCarroll, K G Morgan, A R Morrow and G F Musso

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 229-237;
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The antitumor agent tamoxifen inhibits breakdown of polyphosphoinositides in GH4C1 cells.
Z Y Friedman

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 238-245;
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Involvement of beta-1 and beta-2 adrenergic receptors in the antidepressant-like effects of centrally administered isoproterenol.
J M O'Donnell, S Frith and J Wilkins

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 246-254;
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Antagonists of 5-HT4 receptor-mediated responses in adult hippocampal neurons.
G E Torres, I L Holt and R Andrade

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 255-261;
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Effects of cocaine on the serotonin-induced inward current in rat nodose ganglion neurons.
P Fan, S Visentin and F F Weight

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 262-266;
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Effect of the nonpeptide neurotensin antagonist, SR 48692, and two enantiomeric analogs, SR 48527 and SR 49711, on neurotensin binding and contractile responses in guinea pig ileum and colon.
C Labbé-Jullié, S Deschaintres, D Gully, G Le Fur and P Kitabgi

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 267-276;
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Role of hypogastric nerve activity in opossum internal anal sphincter function: influence of surgical and chemical denervation.
T Shibamoto, S Chakder and S Rattan

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 277-284;
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Age modulates the long-term but not the acute effects of the serotonergic neurotoxicant 3,4-methylenedioxymethamphetamine.
H W Broening, L Bacon and W Slikker

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 285-293;
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Potentiation of lateral hypothalamic and midline mesencephalic brain stimulation reinforcement by nicotine: examination of repeated treatment.
P Bauco and R A Wise

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 294-301;
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Rate-dependent effects of sematilide on action potential duration in isolated guinea pig ventricular myocytes.
T Sawanobori, H Adaniya, T Namiki and M Hiraoka

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 302-310;
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Cocaine interacts with macrophages to modulate mesangial cell proliferation.
J Mattana, N Gibbons and P C Singhal

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 311-318;
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Cocaethylene, a metabolite of cocaine and ethanol, is a potent blocker of cardiac sodium channels.
Y Q Xu, W J Crumb and C W Clarkson

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 319-325;
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Effect of levcromakalim on hypoxia-, KCl- and prostaglandin F2 alpha-induced contractions in isolated rat pulmonary artery.
F Zhang and A H Morice

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 326-333;
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Ethanol enhances inward rectification in rat locus ceruleus neurons by increasing the extracellular potassium concentration.
S S Osmanovic and S A Shefner

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 334-342;
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Pharmacological studies with two new ergoline derivatives, the potential antipsychotics LEK-8829 and LEK-8841.
I Krisch, B Bole-Vunduk, M Pepelnak, B Lavric, A Ocvirk, M V Budihna and D Sket

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 343-352;
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Anxiolytic-like effects of the novel cholinergic channel activator ABT-418.
J D Brioni, A B O'Neill, D J Kim, M J Buckley, M W Decker and S P Arneric

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 353-361;
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Modulation of three types of K+ currents in canine coronary artery smooth muscle cells by NS-004, or 1-(2'-hydroxy-5'-chlorophenyl)-5-trifluoromethyl-2(3H) benzimidazolone.
X Xu, T D Tsai, J Wang, E W Lee and K S Lee

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 362-369;
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Multiple systems for the biliary excretion of organic anions in rats: liquiritigenin conjugates as model compounds.
H Shimamura, H Suzuki, M Hanano, A Suzuki, O Tagaya, T Horie and Y Sugiyama

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 370-378;
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5-Hydroxytryptamine-2 and -4 receptors located on bovine isolated mesenteric lymphatics.
H Miyahara, Y Kawai and T Ohhashi

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 379-385;
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A functional beta-2 adrenoceptor-mediated chronotropic response in isolated guinea pig heart tissue: selectivity of the potent beta-2 adrenoceptor agonist TA 2005.
H P Voss, S Shukrula, T S Wu, D Donnell and A Bast

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 386-389;
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Characterization of dilator prostanoid receptors in the fetal rabbit ductus arteriosus.
G C Smith, R A Coleman and J C McGrath

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 390-396;
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Beta-adrenergic regulation of gap-junctional intercellular communication in cultured rabbit gastric epithelial cells.
F Ueda, Y Kameda, O Yamamoto and Y Shibata

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 397-402;
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Loop diuretics affect transcellular electrolyte transport in cells of the distal convoluted tubule.
F X Beck, A Ohno, A Dörge and K Thurau

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 403-407;
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Induction of heart heme oxygenase-1 (HSP32) by hyperthermia: possible role in stress-mediated elevation of cyclic 3':5'-guanosine monophosphate.
J F Ewing, V S Raju and M D Maines

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 408-414;
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In vitro and in vivo inhibition of rat vascular smooth muscle cell migration and proliferation by a 2-aminochromone U-86983.
L A Erickson, P D Bonin, D G Wishka, J Morris, R J Dalga, D J Williams, G J Wilson, J L Hoover, C A Simmons and S J Humphrey

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 415-421;
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Increases in guanine nucleotide binding to striatal G proteins is associated with dopamine receptor supersensitivity.
P Butkerait, H Y Wang and E Friedman

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 422-428;
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Angiotensin type 1 receptors mediate smooth muscle proliferation and endothelin biosynthesis in rat vascular smooth muscle.
C P Sung, A J Arleth, B L Storer and E H Ohlstein

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 429-437;
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The 21-aminosteroid tirilazad mesylate protects against endotoxin shock and acute liver failure in rats.
P Liu, S L Vonderfecht, G M McGuire, M A Fisher, A Farhood and H Jaeschke

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 438-445;
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Effects of prostacyclin analogs on the synthesis of tissue factor, tumor necrosis factor-alpha and interleukin-1 beta in human monocytic THP-1 cells.
D J Crutchley, L B Conanan and B G Que

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 446-451;
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[125I]iodoproxyfan, a new antagonist to label and visualize cerebral histamine H3 receptors.
X Ligneau, M Garbarg, M L Vizuete, J Diaz, K Purand, H Stark, W Schunack and J C Schwartz

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 452-459;
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Effects of chronic haloperidol and clozapine treatment on neurotensin and c-fos mRNA in rat neostriatal subregions.
K M Merchant, D J Dobie, F M Filloux, M Totzke, M Aravagiri and D M Dorsa

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 460-471;
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Role of thyroid status in the ontogeny of adrenergic cell signaling in rat brain: beta receptors, adenylate cyclase, ornithine decarboxylase and c-fos protooncogene expression.
J P Wagner, F J Seidler, S E Lappi, E C McCook and T A Slotkin

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 472-483;
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[3H]RS-23597-190, a potent 5-hydroxytryptamine4 antagonist labels sigma-1 but not sigma-2 binding sites in guinea pig brain.
D W Bonhaus, D N Loury, L B Jakeman, S A Hsu, Z P To, E Leung, K D Zeitung, R M Eglen and E H Wong

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 484-493;
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Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons. II. The rundown and inward rectification of agonist-elicited whole-cell currents and identification of receptor subunits by in situ hybridization.
M Alkondon, S Reinhardt, C Lobron, B Hermsen, A Maelicke and E X Albuquerque

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 494-506;
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Bradykinin (Bk) increases cytosolic calcium in cultured rat myenteric neurons via Bk-2 type receptors coupled to mobilization of extracellular and intracellular sources of calcium: evidence that calcium influx is prostaglandin dependent.
D Gelperin, D Mann, J del Valle and J W Wiley

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 507-514;
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Nephrotoxicity and hepatotoxicity of 5,6-dichloro-4-thia-5-hexenoic acid: evidence for fatty acid beta-oxidation-dependent bioactivation.
M E Fitzsimmons, R B Baggs and M W Anders

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 515-523;
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Intrastriatal Ro15-4513 functionally antagonizes ethanol-induced motor incoordination and striatal adenosinergic modulation of ethanol-induced motor incoordination in rats.
Z H Meng and M S Dar

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 524-534;
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Biochemical and electrophysiological mechanisms of the positive inotropic effect of calyculin A, a protein phosphatase inhibitor.
J Neumann, P Bokník, S Herzig, W Schmitz, H Scholz, K Wiechen and N Zimmermann

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 535-541;
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Adenosine receptors mediate cellular adaptation to ethanol in NG108-15 cells.
M K Sapru, I Diamond and A S Gordon

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 542-548;
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Use of midazolam as a human cytochrome P450 3A probe: I. In vitro-in vivo correlations in liver transplant patients.
K E Thummel, D D Shen, T D Podoll, K L Kunze, W F Trager, P S Hartwell, V A Raisys, C L Marsh, J P McVicar and D M Barr

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 549-556;
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Use of midazolam as a human cytochrome P450 3A probe: II. Characterization of inter- and intraindividual hepatic CYP3A variability after liver transplantation.
K E Thummel, D D Shen, T D Podoll, K L Kunze, W F Trager, C E Bacchi, C L Marsh, J P McVicar, D M Barr and J D Perkins

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 557-566;
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Induction of 12-lipoxygenase expression by epidermal growth factor is mediated by protein kinase C in A431 cells.
Y W Liu, Y Asaoka, H Suzuki, T Yoshimoto, S Yamamoto and W C Chang

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 567-573;
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EM574, an erythromycin derivative, is a potent motilin receptor agonist in human gastric antrum.
M Satoh, T Sakai, I Sano, K Fujikura, H Koyama, K Ohshima, Z Itoh and S Omura

Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 574-579;

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