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Journal of Pharmacology and Experimental Therapeutics

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Table of Contents

October 01, 1994; Volume 271,Issue 1
  • You have access
    The mycotoxin ochratoxin-A impairs protein uptake in cells derived from the proximal tubule of the kidney (opossum kidney cells).
    M Gekle, S Mildenberger, R Freudinger and S Silbernagl
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 1-6;
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    Substance P activates rat colonic motility via excitatory and inhibitory neural pathways and direct action on muscles.
    U Scheurer, E Drack and F Halter
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 7-13;
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    Glibenclamide reduces the coronary vasoactivity of adenosine receptor agonists.
    K Niiya, S Uchida, T Tsuji and R A Olsson
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 14-19;
  • You have access
    Protective effect of ebselen on constrictive hepatic vasculature: prevention of alcohol-induced effects on portal pressure in perfused livers.
    M Oshita, Y Takei, S Kawano, H Fusamoto and T Kamada
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 20-24;
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    Non-N-methyl-D-aspartate receptor antagonism by 3-N-substituted 2,3-benzodiazepines: relationship to anticonvulsant activity.
    S D Donevan, S Yamaguchi and M A Rogawski
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 25-29;
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    The dihydropyridine nitrendipine reduces N-methyl-D-aspartate (NMDA)-evoked currents of rodent cortical neurons through a direct interaction with the NMDA receptor-associated ion channel.
    G A Skeen, H S White and R E Twyman
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 30-38;
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    NK1 receptors mediated release of 6-keto-PGF1 alpha from the ex vivo perfused canine ileum.
    M B Parrish, K D Rainsford, D M Johnson and E E Daniel
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 39-47;
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    Drug discrimination assessment of agonist-antagonist opioids in humans: a three-choice saline-hydromorphone-butorphanol procedure.
    K L Preston and G E Bigelow
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 48-60;
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    Neuropeptide Y inhibition of nicotinic receptor-mediated chromaffin cell secretion.
    T D Hexum, J Zheng and J Zhu
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 61-66;
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    Magnesium and zinc potentiate ethanol inhibition of N-methyl-D-aspartate-stimulated nitric oxide synthase in cortical neurons.
    L J Chandler, N J Guzman, C Sumners and F T Crews
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 67-75;
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    Inflammation-induced release of excitatory amino acids is prevented by spinal administration of a GABAA but not by a GABAB receptor antagonist in rats.
    K A Sluka, W D Willis and K N Westlund
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 76-82;
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    Serotonin-dopamine interaction in the rat ventral tegmental area: an electrophysiological study in vivo.
    S Prisco, S Pagannone and E Esposito
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 83-90;
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    In vitro N-glucuronidation of SB 47436 (BMS 186295), a new AT1 nonpeptide angiotensin II receptor antagonist, by rat, monkey and human hepatic microsomal fractions.
    L Perrier, M Bourrié, E Marti, C Tronquet, D Massé, Y Berger, J Magdalou and G Fabre
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 91-99;
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    A mechanism of 5-HT3 receptor mediation is involved etiologically in the psychological stress lesion the stomach of the mouse.
    K Nomura, N Maeda, T Yoshino and I Yamaguchi
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 100-106;
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    Dual effects of nordidemnin on WRK1 cells: inhibition of phosphoinositide metabolism and cell proliferation.
    C Dominice, M N Dufour, N Patino, O Manzoni, E Grazzini, P Jouin and G Guillon
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 107-117;
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    Diffusion of morphine-6-beta-D-glucuronide into the neonatal guinea pig brain during drug-induced respiratory depression.
    L J Murphey and G D Olsen
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 118-124;
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    Sensitivity to nicotine and brain nicotinic receptors are altered by chronic nicotine and mecamylamine infusion.
    A C Collins, Y Luo, S Selvaag and M J Marks
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 125-133;
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    Humanized monoclonal antibody DREG-200 directed against I-selectin protects in feline myocardial reperfusion injury.
    M Buerke, A S Weyrich, T Murohara, C Queen, C K Klingbeil, M S Co and A M Lefer
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 134-142;
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    Role of various 5-HT receptor subtypes in mediating neuroendocrine effects of 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane (DOM) in rats.
    C S Aulakh, P Mazzola-Pomietto, J L Hill and D L Murphy
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 143-148;
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    Pharmacological coupling and functional role for the muscarinic receptor subtypes in isolated cells from the circular smooth muscle of the rabbit cecum.
    P Cuq, R Magous and J P Bali
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 149-155;
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    Analysis of the role of endothelin-A and endothelin-B receptors on nociceptive information transmission in the spinal cord with FR139317, an endothelin-A receptor antagonist, and sarafotoxin S6c, an endothelin-B receptor agonist.
    T Yamamoto, N Shimoyama, H Asano and T Mizuguchi
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 156-163;
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    The estrus cycle, sensitivity to convulsants and the anticonvulsant effect of a neuroactive steroid.
    D A Finn and K W Gee
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 164-170;
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    Potentiation of cardiovascular responses to hydralazine by diverse hydrazine derivatives.
    H Vidrio
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 171-175;
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    Influence of dietary fat on the pharmacodynamics of quinidine, procainamide and tocainide in isolated perfused rabbit hearts.
    A M Gillis, M Choi, H J Mathison and H G Parsons
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 176-183;
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    Pro- and antiarrhythmic effects of d-sotalol and dl-sotalol in an isolated tissue model of ischemia and reperfusion.
    J S Pasnani and G R Ferrier
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 184-192;
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    Different combinations of retinoids and vitamin D3 analogs efficiently promote growth inhibition and differentiation of myelomonocytic leukemia cell lines.
    H Defacque, J Dornand, T Commes, S Cabane, C Sevilla and J Marti
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 193-199;
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    Establishing benzodiazepines as oral reinforcers: midazolam and diazepam self-administration in rhesus monkeys.
    R B Stewart, G A Lemaire, J D Roache and R A Meisch
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 200-211;
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    Regulation of [3H]dopamine release from rat striatal slices by sigma receptor ligands.
    G M Gonzalez-Alvear and L L Werling
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 212-219;
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    Ionization and adsorption of a series of local anesthetics in detergent micelles: studies of drug fluorescence.
    S Desai, T Hadlock, C Messam, R Chafetz and G Strichartz
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 220-228;
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    The bradykinin analog RMP-7 increases intracellular free calcium levels in rat brain microvascular endothelial cells.
    S R Doctrow, S M Abelleira, L A Curry, R Heller-Harrison, J W Kozarich, B Malfroy, L A McCarroll, K G Morgan, A R Morrow and G F Musso
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 229-237;
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    The antitumor agent tamoxifen inhibits breakdown of polyphosphoinositides in GH4C1 cells.
    Z Y Friedman
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 238-245;
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    Involvement of beta-1 and beta-2 adrenergic receptors in the antidepressant-like effects of centrally administered isoproterenol.
    J M O'Donnell, S Frith and J Wilkins
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 246-254;
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    Antagonists of 5-HT4 receptor-mediated responses in adult hippocampal neurons.
    G E Torres, I L Holt and R Andrade
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 255-261;
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    Effects of cocaine on the serotonin-induced inward current in rat nodose ganglion neurons.
    P Fan, S Visentin and F F Weight
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 262-266;
  • You have access
    Effect of the nonpeptide neurotensin antagonist, SR 48692, and two enantiomeric analogs, SR 48527 and SR 49711, on neurotensin binding and contractile responses in guinea pig ileum and colon.
    C Labbé-Jullié, S Deschaintres, D Gully, G Le Fur and P Kitabgi
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 267-276;
  • You have access
    Role of hypogastric nerve activity in opossum internal anal sphincter function: influence of surgical and chemical denervation.
    T Shibamoto, S Chakder and S Rattan
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 277-284;
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    Age modulates the long-term but not the acute effects of the serotonergic neurotoxicant 3,4-methylenedioxymethamphetamine.
    H W Broening, L Bacon and W Slikker
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 285-293;
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    Potentiation of lateral hypothalamic and midline mesencephalic brain stimulation reinforcement by nicotine: examination of repeated treatment.
    P Bauco and R A Wise
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 294-301;
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    Rate-dependent effects of sematilide on action potential duration in isolated guinea pig ventricular myocytes.
    T Sawanobori, H Adaniya, T Namiki and M Hiraoka
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 302-310;
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    Cocaine interacts with macrophages to modulate mesangial cell proliferation.
    J Mattana, N Gibbons and P C Singhal
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 311-318;
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    Cocaethylene, a metabolite of cocaine and ethanol, is a potent blocker of cardiac sodium channels.
    Y Q Xu, W J Crumb and C W Clarkson
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 319-325;
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    Effect of levcromakalim on hypoxia-, KCl- and prostaglandin F2 alpha-induced contractions in isolated rat pulmonary artery.
    F Zhang and A H Morice
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 326-333;
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    Ethanol enhances inward rectification in rat locus ceruleus neurons by increasing the extracellular potassium concentration.
    S S Osmanovic and S A Shefner
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 334-342;
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    Pharmacological studies with two new ergoline derivatives, the potential antipsychotics LEK-8829 and LEK-8841.
    I Krisch, B Bole-Vunduk, M Pepelnak, B Lavric, A Ocvirk, M V Budihna and D Sket
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 343-352;
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    Anxiolytic-like effects of the novel cholinergic channel activator ABT-418.
    J D Brioni, A B O'Neill, D J Kim, M J Buckley, M W Decker and S P Arneric
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 353-361;
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    Modulation of three types of K+ currents in canine coronary artery smooth muscle cells by NS-004, or 1-(2'-hydroxy-5'-chlorophenyl)-5-trifluoromethyl-2(3H) benzimidazolone.
    X Xu, T D Tsai, J Wang, E W Lee and K S Lee
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 362-369;
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    Multiple systems for the biliary excretion of organic anions in rats: liquiritigenin conjugates as model compounds.
    H Shimamura, H Suzuki, M Hanano, A Suzuki, O Tagaya, T Horie and Y Sugiyama
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 370-378;
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    5-Hydroxytryptamine-2 and -4 receptors located on bovine isolated mesenteric lymphatics.
    H Miyahara, Y Kawai and T Ohhashi
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 379-385;
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    A functional beta-2 adrenoceptor-mediated chronotropic response in isolated guinea pig heart tissue: selectivity of the potent beta-2 adrenoceptor agonist TA 2005.
    H P Voss, S Shukrula, T S Wu, D Donnell and A Bast
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 386-389;
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    Characterization of dilator prostanoid receptors in the fetal rabbit ductus arteriosus.
    G C Smith, R A Coleman and J C McGrath
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 390-396;
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    Beta-adrenergic regulation of gap-junctional intercellular communication in cultured rabbit gastric epithelial cells.
    F Ueda, Y Kameda, O Yamamoto and Y Shibata
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 397-402;
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    Loop diuretics affect transcellular electrolyte transport in cells of the distal convoluted tubule.
    F X Beck, A Ohno, A Dörge and K Thurau
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 403-407;
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    Induction of heart heme oxygenase-1 (HSP32) by hyperthermia: possible role in stress-mediated elevation of cyclic 3':5'-guanosine monophosphate.
    J F Ewing, V S Raju and M D Maines
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 408-414;
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    In vitro and in vivo inhibition of rat vascular smooth muscle cell migration and proliferation by a 2-aminochromone U-86983.
    L A Erickson, P D Bonin, D G Wishka, J Morris, R J Dalga, D J Williams, G J Wilson, J L Hoover, C A Simmons and S J Humphrey
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 415-421;
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    Increases in guanine nucleotide binding to striatal G proteins is associated with dopamine receptor supersensitivity.
    P Butkerait, H Y Wang and E Friedman
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 422-428;
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    Angiotensin type 1 receptors mediate smooth muscle proliferation and endothelin biosynthesis in rat vascular smooth muscle.
    C P Sung, A J Arleth, B L Storer and E H Ohlstein
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 429-437;
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    The 21-aminosteroid tirilazad mesylate protects against endotoxin shock and acute liver failure in rats.
    P Liu, S L Vonderfecht, G M McGuire, M A Fisher, A Farhood and H Jaeschke
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 438-445;
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    Effects of prostacyclin analogs on the synthesis of tissue factor, tumor necrosis factor-alpha and interleukin-1 beta in human monocytic THP-1 cells.
    D J Crutchley, L B Conanan and B G Que
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 446-451;
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    [125I]iodoproxyfan, a new antagonist to label and visualize cerebral histamine H3 receptors.
    X Ligneau, M Garbarg, M L Vizuete, J Diaz, K Purand, H Stark, W Schunack and J C Schwartz
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 452-459;
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    Effects of chronic haloperidol and clozapine treatment on neurotensin and c-fos mRNA in rat neostriatal subregions.
    K M Merchant, D J Dobie, F M Filloux, M Totzke, M Aravagiri and D M Dorsa
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 460-471;
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    Role of thyroid status in the ontogeny of adrenergic cell signaling in rat brain: beta receptors, adenylate cyclase, ornithine decarboxylase and c-fos protooncogene expression.
    J P Wagner, F J Seidler, S E Lappi, E C McCook and T A Slotkin
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 472-483;
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    [3H]RS-23597-190, a potent 5-hydroxytryptamine4 antagonist labels sigma-1 but not sigma-2 binding sites in guinea pig brain.
    D W Bonhaus, D N Loury, L B Jakeman, S A Hsu, Z P To, E Leung, K D Zeitung, R M Eglen and E H Wong
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 484-493;
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    Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons. II. The rundown and inward rectification of agonist-elicited whole-cell currents and identification of receptor subunits by in situ hybridization.
    M Alkondon, S Reinhardt, C Lobron, B Hermsen, A Maelicke and E X Albuquerque
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 494-506;
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    Bradykinin (Bk) increases cytosolic calcium in cultured rat myenteric neurons via Bk-2 type receptors coupled to mobilization of extracellular and intracellular sources of calcium: evidence that calcium influx is prostaglandin dependent.
    D Gelperin, D Mann, J del Valle and J W Wiley
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 507-514;
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    Nephrotoxicity and hepatotoxicity of 5,6-dichloro-4-thia-5-hexenoic acid: evidence for fatty acid beta-oxidation-dependent bioactivation.
    M E Fitzsimmons, R B Baggs and M W Anders
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 515-523;
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    Intrastriatal Ro15-4513 functionally antagonizes ethanol-induced motor incoordination and striatal adenosinergic modulation of ethanol-induced motor incoordination in rats.
    Z H Meng and M S Dar
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 524-534;
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    Biochemical and electrophysiological mechanisms of the positive inotropic effect of calyculin A, a protein phosphatase inhibitor.
    J Neumann, P Bokník, S Herzig, W Schmitz, H Scholz, K Wiechen and N Zimmermann
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 535-541;
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    Adenosine receptors mediate cellular adaptation to ethanol in NG108-15 cells.
    M K Sapru, I Diamond and A S Gordon
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 542-548;
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    Use of midazolam as a human cytochrome P450 3A probe: I. In vitro-in vivo correlations in liver transplant patients.
    K E Thummel, D D Shen, T D Podoll, K L Kunze, W F Trager, P S Hartwell, V A Raisys, C L Marsh, J P McVicar and D M Barr
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 549-556;
  • You have access
    Use of midazolam as a human cytochrome P450 3A probe: II. Characterization of inter- and intraindividual hepatic CYP3A variability after liver transplantation.
    K E Thummel, D D Shen, T D Podoll, K L Kunze, W F Trager, C E Bacchi, C L Marsh, J P McVicar, D M Barr and J D Perkins
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 557-566;
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    Induction of 12-lipoxygenase expression by epidermal growth factor is mediated by protein kinase C in A431 cells.
    Y W Liu, Y Asaoka, H Suzuki, T Yoshimoto, S Yamamoto and W C Chang
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 567-573;
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    EM574, an erythromycin derivative, is a potent motilin receptor agonist in human gastric antrum.
    M Satoh, T Sakai, I Sano, K Fujikura, H Koyama, K Ohshima, Z Itoh and S Omura
    Journal of Pharmacology and Experimental Therapeutics October 1994, 271 (1) 574-579;
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Journal of Pharmacology and Experimental Therapeutics
Vol. 271, Issue 1
1 Oct 1994
  • Table of Contents
  • Table of Contents (PDF)
  • Index by author
  • Back Matter (PDF)
  • Editorial Board (PDF)
  • Front Matter (PDF)
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  • Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.
  • Functional Selectivity and Classical Concepts of Quantitative Pharmacology
  • Abl Protein-Tyrosine Kinase Inhibitor STI571 Inhibits In Vitro Signal Transduction Mediated by c-Kit and Platelet-Derived Growth Factor Receptors
  • The Prediction of Human Pharmacokinetic Parameters from Preclinical and In Vitro Metabolism Data
  • A METHOD FOR DETERMINING LOSS OF PAIN SENSATION
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