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Abstract

N-aralkylated derivatives of 1-aminobenzotriazole are potent isozyme- and lung-selective mechanism-based inhibitors of guinea pig cytochrome P-450 in vivo.

L C Knickle, R M Philpot and J R Bend
Journal of Pharmacology and Experimental Therapeutics July 1994, 270 (1) 377-385;

Article Information

vol. 270 no. 1 377-385
PubMed 
8035335
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Published online July 1, 1994.

Author Information

  1. L C Knickle,
  2. R M Philpot and
  3. J R Bend
  1. Department of Pharmacology and Toxicology, University of Western Ontario, London, Canada.

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    Abstract

    N-aralkylated derivatives of 1-aminobenzotriazole are potent isozyme- and lung-selective mechanism-based inhibitors of guinea pig cytochrome P-450 in vivo.

    L C Knickle, R M Philpot and J R Bend
    Journal of Pharmacology and Experimental Therapeutics July 1, 1994, 270 (1) 377-385;
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