Journal of Pharmacology and Experimental Therapeutics: 266 (1)

July 01, 1993; Volume 266,Issue 1

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Involvement of cytochrome P-450IIIA in metabolism of potassium canrenoate to an epoxide: mechanism of inhibition of the epoxide formation by spironolactone and its sulfur-containing metabolite.
C S Cook, C Hauswald, J A Oppermann and G L Schoenhard

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 1-7;
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Common phosphatidylinositol 4,5-bisphosphate pools are involved in carbachol and serotonin activation of tracheal smooth muscle.
C B Baron, J Pompeo, D Blackman and R F Coburn

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 8-15;
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Comparison of adenosine and muscarinic receptor-mediated effects on protein phosphatase inhibitor-1 activity in the heart.
R C Gupta, J Neumann and A M Watanabe

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 16-22;
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Diethyldithiocarbamate S-methylation: evidence for catalysis by human liver thiol methyltransferase and thiopurine methyltransferase.
T A Glauser, A N Nelson, D E Zembower, J J Lipsky and R M Weinshilboum

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 23-32;
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Effects of angiotensin-converting enzyme inhibition on renal adaptations to acute furosemide administration in conscious rats.
M Bak, M Shalmi, J S Petersen, L B Poulsen and S Christensen

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 33-40;
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Cocaine enhances postrest and paired-stimulation potentiation in rat papillary muscle.
R G Carpentier, B R Coleman and D J Patel

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 41-46;
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Intracellular calcium mediates the cytotoxicity of lipid A in LLC-PK1 cells.
P R Mayeux and S V Shah

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 47-51;
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Oxidative metabolism of omeprazole in human liver microsomes: cosegregation with S-mephenytoin 4'-hydroxylation.
K Chiba, K Kobayashi, K Manabe, M Tani, T Kamataki and T Ishizaki

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 52-59;
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MK-801 impairs recognition memory in rhesus monkeys: comparison with cholinergic drugs.
H Ogura and T G Aigner

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 60-64;
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Electrogenic and electroneutral HCO3-secretion by guinea pig gallbladder epithelium: discriminatory abilities of Cl- channel blockers.
K U Petersen, P Cormann, H J Macherey, G Sprakties and J M Winterhager

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 65-73;
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Effect of FK1052, a potent 5-hydroxytryptamine3 and 5-hydroxytryptamine4 receptor dual antagonist, on colonic function in vivo.
M Kadowaki, Y Nagakura, M Tomoi, J Mori and M Kohsaka

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 74-80;
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Phenylbutazone peroxidatic metabolism and conjugation.
V M Lakshmi, T V Zenser, M B Mattammal and B B Davis

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 81-88;
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Effect of valproate, sodium 2-propyl-4-pentenoate and sodium 2-propyl-2-pentenoate on renal substrate uptake and ammoniagenesis in the rat.
M Elhamri, B Ferrier, M Martin and G Baverel

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 89-96;
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Neurochemical and behavioral evidence that Ro 41-9067 is a selective presynaptic dopamine receptor agonist.
E Nisoli, C Tonello, R Imhof, R Scherschlicht, M da Prada and M O Carruba

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 97-105;
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Modulation of Mu1 opioid binding by magnesium: evidence for multiple receptor conformations.
K M Standifer, J A Clark and G W Pasternak

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 106-113;
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Pharmacological profile of a highly potent and long-acting angiotensin II receptor antagonist, 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4- yl]methyl]-1H-benzimidazole-7-carboxylic acid (CV-11974), and its prodrug, (+/-)-1-(cyclohexyloxycarbonyloxy)-ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5- yl)biphenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylate (TCV-116).
Y Shibouta, Y Inada, M Ojima, T Wada, M Noda, T Sanada, K Kubo, Y Kohara, T Naka and K Nishikawa

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 114-120;
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Suppression by dynorphin A and [des-Tyr1]dynorphin A peptides of the expression of opiate withdrawal and tolerance in morphine-dependent mice.
A E Takemori, H H Loh and N M Lee

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 121-124;
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Effects of thrombin and thrombin receptor activating peptides on rat aortic vascular smooth muscle.
M J Antonaccio, D Normandin, R Serafino and S Moreland

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 125-132;
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Serotonin 5-HT1A receptors mediate inhibition of tyrosine hydroxylation in rat striatum.
E A Johnson, C E Tsai, Y H Shahan and A J Azzaro

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 133-141;
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Enhancement of glycine release from human brain cortex synaptosomes by acetylcholine acting at M4 muscarinic receptors.
C Russo, M Marchi, G C Andrioli, P Cavazzani and M Raiteri

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 142-146;
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Central nervous and systemic kinetics of ramipril and ramiprilat in the conscious dog.
M Nordström, T Abrahamsson, M Ervik, E Forshult and C G Regårdh

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 147-152;
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Enhancement of gamma-aminobutyric acidA receptor function and binding by the volatile anesthetic halothane.
B Longoni, G C Demontis and R W Olsen

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 153-159;
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Purinergic P2y receptors stimulate renin secretion by rat renal cortical slices.
P C Churchill and V R Ellis

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 160-163;
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Opiate receptors within the blood-brain barrier mediate kappa agonist-induced water diuresis.
D P Brooks, G Giardina, M Gellai, G Dondio, R M Edwards, G Petrone, P D DePalma, M Sbacchi, M Jugus and P Misiano

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 164-171;
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Involvement of the L-arginine: nitric oxide pathway in nonadrenergic noncholinergic relaxation of the cat gastric fundus.
A J Barbier and R A Lefebvre

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 172-178;
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Acetylpolyamines decrease blood pressure, [Ca++]i and isometric force of vascular smooth muscle.
L Y Wing, C F Chan and M J Jiang

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 179-183;
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Naloxone-induced potentiation of cardiac alpha-2 adrenoceptor-mediated depression of neurogenic tachycardia.
K J Slavik and J E Szilagyi

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 184-191;
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Development and in vivo evaluation of metabolically resistant antagonists of B1 receptors for kinins.
G Drapeau, R Audet, L Levesque, D Godin and F Marceau

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 192-199;
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Diuretic and renal protective effects of 8-(noradamantan-3-yl)-1,3-dipropylxanthine (KW-3902), a novel adenosine A1-receptor antagonist, via pertussis toxin insensitive mechanism.
H Mizumoto, A Karasawa and K Kubo

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 200-206;
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L-2-amino-4-phosphonobutanoic acid and 1S,3R-1-aminocyclopentane-1,3-dicarboxylic acid reduce paired-pulse depression recorded from medial perforant path in the dentate gyrus of rat hippocampal slices.
J S Kahle and C W Cotman

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 207-215;
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Anticonvulsant efficacy and adverse effects of phenytoin during chronic treatment in amygdala-kindled rats.
C Rundfeldt and W Löscher

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 216-223;
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Sodium nitroprusside stimulates anion secretion and inhibits sodium chloride absorption in rat colon.
K T Wilson, Y Xie, M W Musch and E B Chang

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 224-230;
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Effects of Agelenopsis aperta toxins on the N-methyl-D-aspartate receptor: polyamine-like and high-affinity antagonist actions.
K Williams

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 231-236;
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Application of transfected cell lines in studies of functional receptor subtype selectivity of muscarinic agonists.
S Z Wang and E E el-Fakahany

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 237-243;
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Modeling of tolerance development and rebound effect during different intravenous administrations of morphine to rats.
M Ekblom, M Hammarlund-Udenaes and L Paalzow

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 244-252;
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The mechanism for the rapid desensitization in bradykinin-stimulated inositol monophosphate production in NG108-15 cells involves interaction of a single receptor with multiple signaling pathways.
D H Wolsing and J S Rosenbaum

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 253-261;
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Protective effect of clentiazem against epinephrine-induced cardiac injury in rats.
T A Deisher, H Narita, P Zera, R Ginsburg, M R Bristow, M E Billingham, M B Fowler and B B Hoffman

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 262-269;
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A new NK1 receptor antagonist (CP-99,994) prevents the increase in tracheal vascular permeability produced by hypertonic saline.
G Piedimonte, C Bertrand, P Geppetti, R M Snider, M C Desai and J A Nadel

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 270-273;
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The baroreceptor mechanism for controlling renin secretion: effect of calcium channel blockers.
T Jones-Dombi and P Churchill

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 274-278;
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Alpha-2 adrenoceptors in medullary thick ascending limbs of the rabbit kidney.
D Mohuczy-Dominiak and L C Garg

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 279-287;
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Extraneuronal metabolism of endogenous and exogenous norepinephrine and epinephrine in rats.
J W Lenders, R Kvetnansky, K Pacak, D S Goldstein, I J Kopin and G Eisenhofer

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 288-293;
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Direct evidence for the coupling of A2-adenosine receptor to stimulatory guanine nucleotide-binding-protein in bovine brain striatum.
R B Marala and S J Mustafa

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 294-300;
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Kinetics of activation and in vivo muscarinic receptor binding of N-(2-bromoethyl)-4-piperidinyl diphenylacetate: an analog of 4-DAMP mustard.
M T Griffin, E A Thomas and F J Ehlert

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 301-305;
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Inhibition of antigen-induced bronchoconstriction and eosinophil infiltration in the guinea pig by the cyclic AMP-specific phosphodiesterase inhibitor, rolipram.
D C Underwood, R R Osborn, L B Novak, J K Matthews, S J Newsholme, B J Undem, J M Hand and T J Torphy

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 306-313;
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Role of prostanoids in the regulation of central cholinergic receptor sensitivity.
J J Buccafusco, C A Lapp, R S Aronstam, A C Hays and L C Shuster

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 314-322;
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Opioid-induced suppression of rat testicular function.
M L Adams, B Sewing, J B Forman, E R Meyer and T J Cicero

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 323-328;
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Characterization of the antinociception produced by intrathecally administered muscarinic agonists in rats.
E T Iwamoto and L Marion

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 329-338;
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Effects of neuropeptide Y and [Leu31,Pro34] neuropeptide Y on experimental gastric lesion formation and gastric secretion in the rat.
S B Penner, D D Smyth and G B Glavin

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 339-343;
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A new prostacyclin analog, KP-10614, inhibits platelet-polymorphonuclear leukocyte interaction and limits experimental infarct size in rat heart.
T Kanayama, Y Kimura and S Mizogami

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 344-349;
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Agonist-induced desensitization of dopamine D-1 receptors in bovine retina and rat striatum.
S Ofori, O Bugnon and M Schorderet

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 350-357;
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Beta 3-adrenoceptors in dog adipose tissue: studies on their involvement in the lipomobilizing effect of catecholamines.
J Galitzky, M Reverte, C Carpene, M Lafontan and M Berlan

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 358-366;
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Ca(++)-independent relaxation mediated by beta adrenoceptor in Ca(++)-independent contraction of uterine smooth muscle.
T Ishine, Y Miyauchi and M K Uchida

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 367-373;
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Effects of diltiazem on calcium metabolism in cultured bovine glomerulosa cells: relationships to the actions of angiotensin II and potassium.
R E Kramer

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 374-384;
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Full and partial agonism displayed by benzodiazepine receptor ligands at recombinant gamma-aminobutyric acidA receptor subtypes.
F Knoflach, U Drescher, L Scheurer, P Malherbe and H Mohler

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 385-391;
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The entire vasoactive intestinal polypeptide molecule is required for the activation of the vasoactive intestinal polypeptide receptor: functional and binding studies on opossum internal anal sphincter smooth muscle.
S Chakder and S Rattan

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 392-399;
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Oleanolic acid protects against cadmium hepatotoxicity by inducing metallothionein.
Y Liu, H Kreppel, J Liu, S Choudhuri and C D Klaassen

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 400-406;
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Effect of calcium channel antagonists on cocaine-induced malignant arrhythmias: protection against ventricular fibrillation.
G E Billman

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 407-416;
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Morphine induces apoptosis in murine thymocytes in vivo but not in vitro: involvement of both opiate and glucocorticoid receptors.
B A Fuchs and S B Pruett

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 417-423;
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Time course of tyrosine hydroxylase expression after behavioral sensitization to cocaine.
B A Sorg, S Y Chen and P W Kalivas

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 424-430;
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Dopamine and acetylcholine cell density in the neuroleptic responsive (NR) and neuroleptic nonresponsive (NNR) lines of mice.
R Hitzemann, Y Qian and B Hitzemann

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 431-438;
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Heterogeneity of alpha-2 adrenoceptors in pregnant rat uterus: identification of subtypes and autoradiographic distribution.
C Legrand, S Mhaouty, C Rigolot and J P Maltier

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 439-449;
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Vascular serotonin 5-hydroxytryptamine2 receptor blockade by LY215840: lack of effect upon neointima formation in balloon-injured rat carotid arteries.
R F Kauffman, J S Bean, W E Bloomquist and M L Cohen

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 450-455;
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Sulphonylurea drugs no longer inhibit ATP-sensitive K+ channels during metabolic stress in cardiac muscle.
I Findlay

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 456-467;
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Guinea pig ileitis is attenuated by the leumedin N-(fluorenyl-9- methoxycarbonyl)-leucine (NPC 15199).
M J Miller, S Chotinaruemol, H Sadowska-Krowikca, X J Zhang, J A McIntyre and D A Clark

Journal of Pharmacology and Experimental Therapeutics July 1993, 266 (1) 468-472;

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