Journal of Pharmacology and Experimental Therapeutics: 261 (1)

April 01, 1992; Volume 261,Issue 1

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Sequestration of organic cations by acidified hepatic endocytic vesicles and implications for biliary excretion.
R W Van Dyke, E D Faber and D K Meijer

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 1-11;
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Predominant role for nitric oxide in the relaxation induced by acetylcholine in cat cerebral arteries.
M J Alonso, M Salaices, C F Sanchez-Ferrer and J Marin

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 12-20;
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Interference with renal organic cation transport by (-)- and (+)-nicotine at concentrations documented in plasma of habitual tobacco smokers.
L T Wong, D D Smyth and D S Sitar

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 21-25;
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Buprenorphine's effects on self-administration of smoked cocaine base and orally delivered phencyclidine, ethanol and saccharin in rhesus monkeys.
M E Carroll, G N Carmona, S A May, S Buzalsky and C Larson

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 26-37;
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An investigation of the acute effect of gentamicin on the renal handling of electrolytes in the rat.
J E Foster, E S Harpur and H O Garland

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 38-43;
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Toxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in primary cultures of mouse astrocytes.
D A Di Monte, E Y Wu, L E Delanney, I Irwin and J W Langston

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 44-49;
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Effect of cyclosporine on colchicine secretion by the kidney multidrug transporter studied in vivo.
K V Speeg, A L Maldonado, J Liaci and D Muirhead

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 50-55;
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In vivo modeling of the pharmacodynamic interaction between benzodiazepines which differ in intrinsic efficacy.
J W Mandema, M T Kuck and M Danhof

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 56-61;
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Discrimination of agonist-antagonist opioids in humans trained on a two-choice saline-hydromorphone discrimination.
K L Preston, I A Liebson and G E Bigelow

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 62-71;
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A further evaluation of the effects of K+ depolarization on glutamate-evoked [3H]dopamine release from striatal slices.
J F Bowyer, G D Newport, G W Lipe and L T Frame

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 72-80;
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Increased sensitivity to the anesthetic effect of phenobarbital in aging BN/BiRij rats.
A M Stijnen, M Danhof and C F Van Bezooijen

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 81-87;
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Modeling of the effect site equilibration kinetics and pharmacodynamics of racemic baclofen and its enantiomers using quantitative EEG effect measures.
J W Mandema, C D Heijligers-Feijen, E Tukker, A G De Boer and M Danhof

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 88-95;
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Renin-angiotensin system inhibition reduces glycine-induced glomerular hyperfiltration in conscious rats.
Y X Wang and D P Brooks

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 96-100;
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Effect of ketamine HCl on norepinephrine disposition in isolated ferret ventricular myocardium.
D J Cook, P R Housmans and D K Rorie

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 101-107;
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Role of the gamma-aminobutyric acid receptor/chloride channel complex in tolerance to ethanol and cross-tolerance to diazepam and pentobarbital.
S J Mihic, H Kalant, J F Liu and P H Wu

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 108-113;
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Marijuana smoking: effect of varying delta 9-tetrahydrocannabinol content and number of puffs.
J L Azorlosa, S J Heishman, M L Stitzer and J M Mahaffey

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 114-122;
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In vivo electrophysiological evidence for a selective modulation of N-methyl-D-aspartate-induced neuronal activation in rat CA3 dorsal hippocampus by sigma ligands.
F P Monnet, G Debonnel and C de Montigny

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 123-130;
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Pharmacological characterization of potent, long-acting thromboxane receptor antagonists, SQ 33,261 and SQ 33,552.
D N Harris, I M Michel, H J Goldenberg, K S Hartl, G T Allen, T E Steinbacher, W A Schumacher, W C Han, S E Hall and D M Floyd

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 131-137;
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Punishment of schedule-controlled behavior with beta-carboline injections: antagonism and comparisons with other compounds.
K Takada, J E Barrett, M S Allen, J M Cook and J L Katz

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 138-145;
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Naloxone and norbinaltorphimine administered intracerebroventricularly antagonize spinal morphine-induced antinociception in mice through the antianalgesic action of spinal dynorphin A (1-17).
B B Holmes and J M Fujimoto

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 146-153;
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The relaxant properties in guinea pig airways of S-nitrosothiols.
A Jansen, J Drazen, J A Osborne, R Brown, J Loscalzo and J S Stamler

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 154-160;
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Identification of spinal 5-HT1C binding sites in the rat: characterization of [3H]mesulergine binding.
M R Pranzatelli, J N Murthy and R S Pluchino

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 161-165;
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Comparative action of methylmercury and divalent inorganic mercury on nerve terminal and intraterminal mitochondrial membrane potentials.
M F Hare and W D Atchison

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 166-172;
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Classical genetic analyses of responses to nicotine and ethanol in crosses derived from long- and short-sleep mice.
C M de Fiebre and A C Collins

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 173-180;
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Inhibition of the enkephalin-metabolizing enzymes by the first systemically active mixed inhibitor prodrug RB 101 induces potent analgesic responses in mice and rats.
F Noble, J M Soleilhac, E Soroca-Lucas, S Turcaud, M C Fournie-Zaluski and B P Roques

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 181-190;
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Effect of newly developed tachykinin agonist and antagonists on the guinea pig isolated gallbladder.
R Patacchini and C A Maggi

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 191-194;
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Transepithelial transport of oral cephalosporins by monolayers of intestinal epithelial cell line Caco-2: specific transport systems in apical and basolateral membranes.
K Inui, M Yamamoto and H Saito

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 195-201;
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LY215840, a potent 5-hydroxytryptamine (5-HT)2 receptor antagonist, blocks vascular and platelet 5-HT2 receptors and delays occlusion in a rabbit model of thrombosis.
M L Cohen, D W Robertson, W E Bloomquist and H C Wilson

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 202-208;
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Activation of a relaxation cascade in isolated coronary arteries by brief electrical pulses.
S Kalsner

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 209-224;
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Baroreflex changes produced by serotonergic or catecholaminergic lesions in the rat nucleus tractus solitarius.
H Itoh, R H Alper and R D Buñag

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 225-233;
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Different susceptibility of vasodilator nerve, endothelium and smooth muscle functions to Ca++ antagonists in cerebral arteries.
N Toda and T Okamura

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 234-239;
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Pressor and renal vasoconstrictor effects of NG-nitro-L-arginine as affected by blockade of pressor mechanisms mediated by the sympathetic nervous system, angiotensin, prostanoids and vasopressin.
M L Pucci, L Lin and A Nasjletti

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 240-245;
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Discriminative stimulus effects of morphine: effects of training dose on agonist and antagonist effects of mu opioids.
A M Young, M A Masaki and C Geula

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 246-257;
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Highly potent beta-2 sympathomimetics convert to less potent partial agonists as relaxants of guinea pig tracheae maximally contracted by carbachol. Comparison of relaxation with receptor binding and adenylate cyclase stimulation.
H Lemoine and C Overlack

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 258-270;
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Desensitization and down-regulation of the 5-hydroxytryptamine1B receptor in the opossum kidney cell line.
R C Pleus and D B Bylund

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 271-277;
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Differential influence of N-dealkylation on the stimulus properties of some opioid agonists.
A J Bertalmio, F Medzihradsky, G Winger and J H Woods

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 278-284;
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Chronic benzodiazepine administration. X. Concurrent administration of the peripheral-type benzodiazepine ligand PK11195 attenuates chronic effects of lorazepam.
L G Miller, W R Galpern, J J Byrnes, D J Greenblatt and R I Shader

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 285-289;
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Pharmacodynamics and pharmacokinetics of intravenously administered morphine in spontaneously hypertensive and normotensive Wistar-Kyoto rats.
H N Bhargava and V M Villar

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 290-296;
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Role of the serotonin3 receptor in stress-induced defecation.
K Miyata, T Kamato, A Nishida, H Ito, H Yuki, M Yamano, R Tsutsumi, Y Katsuyama and K Honda

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 297-303;
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Alteration of general anesthetic potency by agonists and antagonists of the polyamine binding site of the N-methyl-D-aspartate receptor.
L C Daniell

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 304-310;
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Effects of buprenorphine and other opioid agonists and antagonists on alfentanil- and cocaine-reinforced responding in rhesus monkeys.
G Winger, P Skjoldager and J H Woods

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 311-317;
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On the mechanism of vasodilating action of berberine: possible role of inositol lipid signaling system.
S Bova, R Padrini, W F Goldman, D M Berman and G Cargnelli

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 318-323;
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Dihydropyridine- and omega-conotoxin-resistant, neomycin-sensitive calcium channels mediate the depolarization-induced increase in internal calcium levels in cortical slices from immature rat brain.
M L Perrier, B Scatton and J Benavides

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 324-330;
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Pyrazole, an alcohol dehydrogenase inhibitor, has dual effects on N-methyl-D-aspartate receptors of hippocampal pyramidal cells: agonist and noncompetitive antagonist.
E F Pereira, Y Aracava, R S Aronstam, E J Barreiro and E X Albuquerque

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 331-340;
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D1 and D2 dopamine receptor distribution in the neuroleptic nonresponsive and neuroleptic responsive lines of mice, a quantitative receptor autoradiographic study.
Y Qian, B Hitzemann and R Hitzemann

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 341-348;
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Effects of N-methyl-D-aspartate receptor antagonists on carbon monoxide-induced brain damage in mice.
H Ishimaru, A Katoh, H Suzuki, T Fukuta, T Kameyama and T Nabeshima

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 349-352;
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Relationship of cytochrome P-450 activity to Clara cell cytotoxicity. I. Histopathologic comparison of the respiratory tract of mice, rats and hamsters after parenteral administration of naphthalene.
C G Plopper, C Suverkropp, D Morin, S Nishio and A Buckpitt

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 353-363;
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Relationship of cytochrome P450 activity to Clara cell cytotoxicity. II. Comparison of stereoselectivity of naphthalene epoxidation in lung and nasal mucosa of mouse, hamster, rat and rhesus monkey.
A Buckpitt, M Buonarati, L B Avey, A M Chang, D Morin and C G Plopper

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 364-372;
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Impaired expression of microsomal cytochrome P450 2C11 in choline-deficient rat liver during the development of cirrhosis.
M Murray, E Cantrill, I Mehta and G C Farrell

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 373-380;
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Metabolism rate of oxodipine in rats and humans: comparison of in vivo and in vitro data.
J P Flinois, M Chabin, F Egros, A Dufour, I de Waziers, C Mas-Chamberlin and P H Beaune

Journal of Pharmacology and Experimental Therapeutics April 1992, 261 (1) 381-386;

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