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Abstract

Opioid and nonopioid components independently contribute to the mechanism of action of tramadol, an 'atypical' opioid analgesic.

R B Raffa, E Friderichs, W Reimann, R P Shank, E E Codd and J L Vaught
Journal of Pharmacology and Experimental Therapeutics January 1992, 260 (1) 275-285;

Article Information

vol. 260 no. 1 275-285
PubMed 
1309873
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Published online January 1, 1992.

Author Information

  1. R B Raffa,
  2. E Friderichs,
  3. W Reimann,
  4. R P Shank,
  5. E E Codd and
  6. J L Vaught
  1. R. W. Johnson Pharmaceutical Research Institute, Spring House, Pennsylvania 19477-0776.

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    Abstract

    Opioid and nonopioid components independently contribute to the mechanism of action of tramadol, an 'atypical' opioid analgesic.

    R B Raffa, E Friderichs, W Reimann, R P Shank, E E Codd and J L Vaught
    Journal of Pharmacology and Experimental Therapeutics January 1, 1992, 260 (1) 275-285;
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