Journal of Pharmacology and Experimental Therapeutics: 256 (2)

February 01, 1991; Volume 256,Issue 2

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CGP 12177A modulates brown fat adenylate cyclase activity by interacting with two distinct receptor sites.
J G Granneman and C J Whitty

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 421-425;
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A functional assay to measure postsynaptic gamma-aminobutyric acidB responses in cultured spinal cord neurons: heterologous regulation of the same K+ channel.
G L Kamatchi and M K Ticku

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 426-431;
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Anticonvulsant and behavioral effects of two novel competitive N-methyl-D-aspartic acid receptor antagonists, CGP 37849 and CGP 39551, in the kindling model of epilepsy. Comparison with MK-801 and carbamazepine.
W Löscher and D Hönack

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 432-440;
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Release of nitric oxide upon stimulation of nonadrenergic noncholinergic nerves in the rat gastric fundus.
G E Boeckxstaens, P A Pelckmans, J J Bogers, H Bult, J G De Man, L Oosterbosch, A G Herman and Y M Van Maercke

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 441-447;
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Heroin acts on different opioid receptors than morphine in Swiss Webster and ICR mice to produce antinociception.
J J Rady, S C Roerig and J M Fujimoto

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 448-457;
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The fate of diastereomeric glutathione conjugates of alpha-bromoisovalerylurea in blood in the rat in vivo and in the perfused liver. Stereoselectivity in biliary and urinary excretion.
M Polhuijs, D K Meijer and G J Mulder

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 458-461;
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L-651,582 inhibition of intracellular parasitic protozoal growth correlates with host-cell directed effects.
D J Hupe, E R Pfefferkorn, N D Behrens and K Peters

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 462-467;
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Allosteric interactions at the m1, m2 and m3 muscarinic receptor subtypes.
N H Lee and E E el-Fakahany

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 468-479;
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RP 49356 and cromakalim relax airway smooth muscle in vitro by opening a sulphonylurea-sensitive K+ channel: a comparison with nifedipine.
D Raeburn and T J Brown

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 480-485;
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Intrarenally produced angiotensin II opposes the natriuretic action of the dopamine-1 receptor agonist fenoldopam in rats.
C J Chen, S Apparsundaram and M F Lokhandwala

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 486-491;
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Characterization of K+ channel-dependent as well as -independent components of pinacidil-induced vasodilation.
K D Meisheri, M A Swirtz, S S Purohit, L A Cipkus-Dubray, S A Khan and J J Oleynek

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 492-499;
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Kappa opioid receptor-mediated regulation of dopaminergic neurons in the rat brain.
J Manzanares, K J Lookingland and K E Moore

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 500-505;
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Competitive and noncompetitive antagonists at N-methyl-D-aspartate receptors protect against methamphetamine-induced dopaminergic damage in mice.
P K Sonsalla, D E Riordan and R E Heikkila

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 506-512;
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Reserpine-induced supersensitivity in rat caudal artery: influence of age.
S P Duckles

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 513-518;
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Interactions of sigma and phencyclidine receptor ligands with the norepinephrine uptake carrier in both rat brain and rat tail artery.
T Massamiri and S P Duckles

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 519-524;
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Effects of pirenzepine and AF-DX 116 on ganglionic transmission in the cardiac sympathetic nerves of the dog: interaction of M1 and M2 receptors with nicotinic receptors.
O Mukaiyama, A Takeuchi, T Kimura and S Satoh

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 525-529;
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Effects of spiperone, raclopride, SCH 23390 and clozapine on apomorphine inhibition of sensorimotor gating of the startle response in the rat.
N R Swerdlow, V A Keith, D L Braff and M A Geyer

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 530-536;
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Superoxide production in the isolated rabbit aorta and the effect of alloxan, indomethacin and nitrovasodilators.
K F Heim, G Thomas and P W Ramwell

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 537-541;
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Contrasting effects of changes in salt balance on the renovascular response to A1-adenosine receptor stimulation in vivo and in vitro in the rat.
A S Nies, M L Beckmann and J G Gerber

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 542-546;
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Prostaglandin E2-induced diarrhea in mice: importance of colonic secretion.
P J Rivière, S C Farmer, T F Burks and F Porreca

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 547-552;
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Mutual-effect amplification of contractile responses elicited by simultaneous activation of alpha-1 adrenergic and 5-hydroxytryptamine2 receptors in isolated rat aorta.
G J Christ and M Jean-Jacques

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 553-561;
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Enantiomers of oxybutynin: in vitro pharmacological characterization at M1, M2 and M3 muscarinic receptors and in vivo effects on urinary bladder contraction, mydriasis and salivary secretion in guinea pigs.
L Noronha-Blob and J F Kachur

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 562-567;
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Evidence for a functional tissue renin-angiotensin system in the rat mesenteric vasculature and its involvement in regulating blood pressure.
R E Weishaar, R L Panek, T C Major, J Simmerman, S T Rapundalo and D G Taylor

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 568-574;
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The role of opioid receptor density in morphine tolerance.
K Lutfy and B C Yoburn

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 575-580;
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Endothelin binding and receptor down regulation in rat glomerular mesangial cells.
E Baldi and M J Dunn

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 581-586;
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Micropuncture evaluation of the site of action of 2-aminomethyl-4-(1,1-dimethylethyl)-6-iodophenol hydrochloride (MK447) in the rat kidney.
P A Johnston and S T Kau

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 587-591;
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Extremely long protection by pyrazole derivatives against chemically induced gastric mucosal injury.
J Hauser and S Szabo

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 592-598;
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The role of alpha adrenoceptor subtypes in sympathetic control of the acral-cutaneous microcirculation.
R N Willette, J P Hieble and C F Sauermelch

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 599-605;
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An imidazoline-specific mechanism for the hypotensive effect of clonidine: a study with yohimbine and idazoxan.
E Tibiriça, J Feldman, C Mermet, F Gonon and P Bousquet

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 606-613;
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Comparative effects of angiotensin II and angiotensin III in rabbit adrenal and aortic tissues.
R G Pendleton, G Gessner and E Horner

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 614-620;
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Cardiac adenylate cyclase activity, positive chronotropic and inotropic effects of forskolin analogs with either low, medium or high binding site affinity.
J W Hubbard, P G Conway, L C Nordstrom, H B Hartman, Y Lebedinsky, G J O'Malley and R W Kosley

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 621-627;
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Characterization of the endothelin binding site on bovine adrenomedullary chromaffin cells: comparison with vascular smooth muscle cells. Evidence for receptor heterogeneity.
L C Wilkes and M R Boarder

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 628-633;
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D-2 dopamine receptors inhibit release of aspartate and glutamate in rat retina.
Y Kamisaki, T Hamahashi, C Mita and T Itoh

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 634-638;
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The effects of the putative potassium channel activator WAY-120,491 on 86Rb efflux from the rabbit aorta.
N J Lodge, R B Cohen, C N Havens and T J Colatsky

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 639-644;
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Evidence for intraluminal Ca++ regulatory site defect in sarcoplasmic reticulum from malignant hyperthermia pig muscle.
T E Nelson, M Lin and P Volpe

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 645-649;
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Hydrolysis of [Leu]enkephalin by chick plasma in vitro.
S Shibanoki, S B Weinberger, D Beniston, K A Nudelman, G Schulteis, E L Bennett, M R Rosenzweig, K Ishikawa and J L Martinez

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 650-655;
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Serotonergic neurons do not influence the regulation of beta adrenoceptors induced by either desipramine or isoproterenol.
J G Hensler, G A Ordway, C Gambarana, P Areso and A Frazer

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 656-664;
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Nephrotoxicity of the glutathione conjugate of menadione (2-methyl-1, 4-naphthoquinone) in the isolated perfused rat kidney. Role of metabolism by gamma-glutamyltranspeptidase and probenecid-sensitive transport.
F A Redegeld, G A Hofman, P G van de Loo, A S Koster and J Noordhoek

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 665-669;
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Classification of postjunctional beta adrenoceptors mediating relaxation of canine bronchi.
L J Janssen and E E Daniel

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 670-676;
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Endothelial cyclic GMP and cyclic AMP do not regulate the release of endothelium-derived relaxing factor/nitric oxide from bovine aortic endothelial cells.
M Kuhn, A Otten, J C Frölich and U Förstermann

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 677-682;
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Endothelium-independent and endothelium-dependent contractions mediated by P2X- and P2Y-purinoceptors in canine basilar arteries.
H Shirahase, H Usui, H Shimaji, K Kurahashi and M Fujiwara

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 683-688;
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Pharmacologic comparison of selected agonists for the M1 muscarinic receptor in transfected murine fibroblast cells (B82).
L Mei, J Lai, H I Yamamura and W R Roeske

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 689-694;
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CCK-8, CCK-4 and gastrin-induced contractions in guinea pig ileum: evidence for differential release of acetylcholine and substance P by CCK-A and CCK-B receptors.
V L Lucaites, L G Mendelsohn, N R Mason and M L Cohen

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 695-703;
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The hemodynamic effects of S-nitrosocaptopril in anesthetized dogs.
J E Shaffer, F Lee, S Thomson, B J Han, J P Cooke and J Loscalzo

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 704-709;
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Effect of chronic D-Ala,2 D-Leu5-enkephalin or pertussis toxin treatment on the high-affinity state of delta opioid receptor in neuroblastoma x glioma NG108-15 hybrid cells.
P Y Law, D S Hom and H H Loh

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 710-716;
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Differential regulation of human basophil and lung mast cell function by adenosine.
P T Peachell, L M Lichtenstein and R P Schleimer

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 717-726;
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Antagonist binding profiles of five cloned human muscarinic receptor subtypes.
F Dörje, J Wess, G Lambrecht, R Tacke, E Mutschler and M R Brann

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 727-733;
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Pharmacological characteristics of high-affinity serotonin uptake systems established through gene transfer.
J V Frnka, A S Chang and D M Lam

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 734-740;
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Behavioral and neurochemical changes in rats dosed repeatedly with diisopropylfluorophosphate.
P J Bushnell, S S Padilla, T Ward, C N Pope and V B Olszyk

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 741-750;
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Dopaminergic structure-activity relationships of 2-aminoindans and cardiovascular action and dopaminergic activity of 4-hydroxy, 5-methyl, 2-di-n-propylaminoindan (RD-211).
S X Ma, J P Long, J R Flynn, P A Leonard and J G Cannon

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 751-756;
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Role of thyroid hormone in the development of beta adrenergic control of ornithine decarboxylase in rat heart and kidney.
J B Pracyk, S E Lappi and T A Slotkin

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 757-766;
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Selective distribution of alpha-1 and beta adrenoceptors in pregnant rat uterus visualized by autoradiography.
C Legrand, V Vivat, C Rigolot and J P Maltier

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 767-772;
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Gastrointestinal serotonin: depletion due to tetrahydrobiopterin deficiency induced by 2,4-diamino-6-hydroxypyrimidine administration.
T Kobayashi, H Hasegawa, E Kaneko and A Ichiyama

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 773-779;
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Therapeutic defibrination with ancrod does not protect canine myocardium from reperfusion injury.
P J Simpson, J A Schelm and G F Smith

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 780-786;
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The 5-hydroxytryptamine2 agonist, (+-)-1-(2,5-dimethoxy-4-bromophenyl)-2-aminopropane stimulates the hypothalamic-pituitary-adrenal (HPA) axis. I. Acute effects on HPA axis activity and corticotropin-releasing factor-containing neurons in the rat brain.
M J Owens, D L Knight, J C Ritchie and C B Nemeroff

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 787-794;
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The 5-hydroxytryptamine2 agonist, (+-)-1-(2,5-dimethoxy-4-bromophenyl)-2-aminopropane stimulates the hypothalamic-pituitary-adrenal (HPA) axis. II. Biochemical and physiological evidence for the development of tolerance after chronic administration.
M J Owens, D L Knight, J C Ritchie and C B Nemeroff

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 795-800;
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Peripheral alpha-1 and alpha-2 adrenergic receptors in three models of hypertension in rats: an in vitro autoradiography study.
S K Wilson

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 801-810;
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Quantitative autoradiographic characterization of the binding of (+)-5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5, 10-imine ([3H]MK-801) in rat brain: regional effects of polyamines.
S Subramaniam and P McGonigle

Journal of Pharmacology and Experimental Therapeutics February 1991, 256 (2) 811-819;

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