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Journal of Pharmacology and Experimental Therapeutics

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Table of Contents

April 01, 1990; Volume 253,Issue 1
  • You have access
    On the mechanism of the different sensitivity of Purkinje and myocardial fibers to strophanthidin.
    G Iacono and M Vassalle
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 1-12;
  • You have access
    The interaction of amitriptyline, doxepin, imipramine and their N-methyl quaternary ammonium derivatives with subtypes of muscarinic receptors in brain and heart.
    F J Ehlert, F M Delen, S H Yun and H A Liem
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 13-19;
  • You have access
    Endothelial nitric oxide generating enzyme(s) in the bovine aorta: subcellular location and metabolic characterization.
    K M Boje and H L Fung
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 20-26;
  • You have access
    Histamine and methacholine aerosol bronchial challenge in awake guinea pigs.
    M J Wiester, J S Tepper, M F Weber and M G Ménache
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 27-33;
  • You have access
    Mechanisms of amphotericin B-induced reduction of the glomerular filtration rate: a micropuncture study.
    R Sabra, K Takahashi, R A Branch and K F Badr
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 34-37;
  • You have access
    Persistence of neurochemical changes in dopamine systems after repeated cocaine administration.
    J Peris, S J Boyson, W A Cass, P Curella, L P Dwoskin, G Larson, L H Lin, R P Yasuda and N R Zahniser
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 38-44;
  • You have access
    Effects of protein binding and experimental disease states on brain uptake of benzodiazepines in rats.
    T H Lin and J H Lin
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 45-50;
  • You have access
    Heterogeneity of high-affinity nicotinic [3H]acetylcholine binding sites.
    R J Lukas
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 51-57;
  • You have access
    Antagonism of leukotriene B4 receptors does not limit canine myocardial infarct size.
    R A Hahn, B R MacDonald, P J Simpson, B D Potts and C J Parli
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 58-66;
  • You have access
    Dissociation of mu opioid tolerance from receptor down-regulation in rat spinal cord.
    K Nishino, Y F Su, C S Wong, W D Watkins and K J Chang
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 67-72;
  • You have access
    Differential regulation of heme and drug metabolism in rat testis and prostate: response to cis-platinum and human chorionic gonadotropin.
    M Iscan and M D Maines
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 73-79;
  • You have access
    Pharmacological differentiation of angiotensin effects in the rabbit isolated vas deferens with dithiothreitol and pertussis toxin.
    G J Trachte
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 80-84;
  • You have access
    Effect of phenylpiperidine opioid antagonists on food consumption and weight gain of the obese Zucker rat.
    W N Shaw, C H Mitch, J D Leander and D M Zimmerman
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 85-89;
  • You have access
    Contrasting effect of thromboxane synthase inhibitors and a thromboxane receptor antagonist on the development of angiotensin II-salt-induced hypertension in rats.
    M Mistry and A Nasjletti
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 90-94;
  • You have access
    Electrophysiological evidence that ethanol alters function of medial septal area without affecting lateral septal function.
    B S Givens and G R Breese
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 95-103;
  • You have access
    Effects of repeated fenfluramine administration on indices of monoamine function in rat brain: pharmacokinetic, dose response, regional specificity and time course data.
    R Zaczek, G Battaglia, S Culp, N M Appel, J F Contrera and E B De Souza
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 104-112;
  • You have access
    Uptake kinetics of 2',3'-dideoxyinosine into brain and cerebrospinal fluid of rats: intravenous infusion studies.
    B D Anderson, B L Hoesterey, D C Baker and R E Galinsky
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 113-118;
  • You have access
    Effect of enalapril or the thromboxane receptor antagonist, daltroban, in rats with subtotal renal ablation.
    D P Brooks, L C Contino, W Trizna, R M Edwards, E H Ohlstein and H A Solleveld
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 119-123;
  • You have access
    Multiple vascular effects of sigma and PCP ligands: inhibition of amine uptake and contractile responses.
    T Massamiri and S P Duckles
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 124-129;
  • You have access
    Competitive and noncompetitive N-methyl-D-aspartate antagonists modify hypoxia-induced membrane potential changes and protect rat hippocampal slices from functional failure: a quantitative comparison.
    J J Grigg and E G Anderson
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 130-135;
  • You have access
    Effects of dose, age, inhibition of metabolism and elimination on the toxicokinetics of 2-butoxyethanol and its metabolites.
    B I Ghanayem, J M Sanders, A M Clark, J Bailer and H B Matthews
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 136-143;
  • You have access
    Opioid regulation of mucosal ion transport in the mouse isolated jejunum.
    R J Sheldon, P J Rivière, M E Malarchik, H I Moseberg, T F Burks and F Porreca
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 144-151;
  • You have access
    Effects of sympathetic activation on plasma renin activity in the developing rat.
    R F Kirby and A K Johnson
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 152-157;
  • You have access
    Age-dependent baroreflex attenuation by centrally infused verapamil in rats.
    D L Barringer and R D Buñag
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 158-164;
  • You have access
    Centrally active antimuscarinic analogs of oxotremorine selectively block physostigmine-induced hypertension, but not peripheral muscarinic vasodepression.
    H M Vargas and B Ringdahl
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 165-170;
  • You have access
    Cardiac dysfunction caused by recombinant human C5A anaphylatoxin: mediation by histamine, adenosine and cyclooxygenase arachidonate metabolites.
    U del Balzo, I Sakuma and R Levi
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 171-179;
  • You have access
    Different patterns of autonomic nerve activity produced by a polar vs. a neutral cardiac glycoside.
    W R Rebagay and R W Caldwell
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 180-184;
  • You have access
    Activation of protein kinase C inhibits internalization and downregulation of muscarinic receptors in 1321N1 human astrocytoma cells.
    R K Hoover and M L Toews
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 185-191;
  • You have access
    Maternal age and blood alcohol concentration in the pregnant Long-Evans rat.
    M W Church, E L Abel, B A Dintcheff and C Matyjasik
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 192-199;
  • You have access
    [Tyr0]-calcitonin gene-related peptide 28-37 (rat) as a putative antagonist of calcitonin gene-related peptide responses on opossum internal anal sphincter smooth muscle.
    S Chakder and S Rattan
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 200-206;
  • You have access
    Chronic treatment with propranolol enhances the synthesis of prostaglandins E2 and I2 by the aorta of spontaneously hypertensive rats.
    T Nishimiya, H B Daniell, J G Webb, J Oatis, T Walle, T E Gaffney and P V Halushka
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 207-213;
  • You have access
    Characterization of D1 dopamine receptors in the bovine pineal gland with [3H]SCH 23390.
    V Simonneaux, L C Murrin and M Ebadi
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 214-220;
  • You have access
    Subtype-selective regulation of beta adrenergic receptor-adenylyl cyclase coupling by phorbol esters in 3T3-L1 fibroblasts.
    M T Nakada, J M Stadel and S T Crooke
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 221-229;
  • You have access
    Effects of plasma protein binding displacement on the pharmacokinetics, tissue and tumor concentrations and efficacy of brequinar, a highly protein-bound antitumor agent.
    B J Aungst, J A Blake, N J Rogers and B A Dusak
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 230-236;
  • You have access
    Operant acquisition of alcohol by women.
    N K Mello, J H Mendelson, S Palmieri, B W Lex and S K Teoh
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 237-245;
  • You have access
    Pharmacological characterization of rat renal medulla dopamine-sensitive cyclic adenosine monophosphate generating system.
    F Amenta, A Ricci and J A Vega
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 246-249;
  • You have access
    Inotropic, electrophysiological and biochemical responses to histamine in rabbit papillary muscles: evidence for coexistence of H1- and H2-receptors.
    Y Hattori, H Nakaya, M Endou and M Kanno
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 250-256;
  • You have access
    Molecular mechanisms of homologous desensitization and internalization of muscarinic receptors in primary cultures of neonatal corticostriatal neurons.
    C Eva, S R Gamalero, E Genazzani and E Costa
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 257-265;
  • You have access
    Contribution of renal nerves to the natriuretic and diuretic effect of alpha-2 adrenergic receptor activation.
    R L Kline and P F Mercer
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 266-271;
  • You have access
    Comparison between the vasoactive actions of endothelin and arginine vasopressin in pithed rats after pretreatment with BAY K 8644, nifedipine or pertussis toxin.
    R Tabrizchi and C R Triggle
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 272-276;
  • You have access
    Calcium antagonists show two modes of protection in ischemic heart failure.
    F T van Amsterdam, N C Punt, M Haas and J Zaagsma
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 277-283;
  • You have access
    Eltoprazine suppresses hyperpolarizing responses to serotonin in rat hippocampus.
    M Joëls, C M Pennartz, H Sijbesma and J Schipper
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 284-289;
  • You have access
    Adenosine receptors are coupled negatively to release of tachykinin(s) from enteric nerve endings.
    F L Christofi, T J McDonald and M A Cook
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 290-295;
  • You have access
    Inotropic and lusitropic effects of chlorpromazine on rat left ventricular papillary muscle.
    M Clergue, B Riou and Y Lecarpentier
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 296-304;
  • You have access
    Assessment of cyclosporine A interactions with human plasma lipoproteins in vitro and in vivo in the rat.
    S Urien, R Zini, M Lemaire and J P Tillement
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 305-309;
  • You have access
    Functional determination of McN-A-343 affinity for M1 muscarinic receptors.
    R Micheletti and A Schiavone
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 310-314;
  • You have access
    In vivo evidence for carrier-mediated uptake of beta-lactam antibiotics through organic anion transport systems in rat kidney and liver.
    A Tsuji, T Terasaki, I Tamai and K Takeda
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 315-320;
  • You have access
    Effect of lithium on renal transport and utilization of alpha-ketoglutarate in the rat.
    B Ferrier, M Martin and G Baverel
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 321-327;
  • You have access
    Platelet-activating factor antagonists treatment protects against postischemic acute renal failure in rats.
    A López-Farré, F Bernabeu, D Gómez-Garre, S Ramon y Cajal, P Braquet and J M López-Novoa
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 328-333;
  • You have access
    Abecarnil, a metabolically stable, anxioselective beta-carboline acting at benzodiazepine receptors.
    D N Stephens, H H Schneider, W Kehr, J S Andrews, K J Rettig, L Turski, R Schmiechen, J D Turner, L H Jensen and E N Petersen
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 334-343;
  • You have access
    Anticonvulsant action of the beta-carboline abecarnil: studies in rodents and baboon, Papio papio.
    L Turski, D N Stephens, L H Jensen, E N Petersen, B S Meldrum, S Patel, J B Hansen, W Löscher, H H Schneider and R Schmiechen
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 344-352;
  • You have access
    Autonomic modulation of the frequency-dependent actions of diltiazem on the atrioventricular node in anesthetized dogs.
    M Nayebpour, M Talajic, W Jing and S Nattel
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 353-361;
  • You have access
    Pharmacokinetic and pharmacodynamic actions of enalapril in humans: effect of probenecid pretreatment.
    F H Noormohamed, W R McNabb and A F Lant
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 362-368;
  • You have access
    Alteration of plasma sex hormone levels associated with old age and its effect on hepatic drug metabolism in rats.
    S Fujita, M Chiba, M Ohta, K Kitani and T Suzuki
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 369-374;
  • You have access
    Alpha adrenoceptor activation and postreceptor contractile mechanisms in the human digital artery.
    M J Stevens and R F Moulds
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 375-380;
  • You have access
    Distribution of substance P receptors in rabbit airways, functional and autoradiographic studies.
    J Black, L Diment, C Armour, L Alouan and P Johnson
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 381-386;
  • You have access
    Cytochrome P 450 isoenzymes, epoxide hydrolase and glutathione transferases in rat and human hepatic and extrahepatic tissues.
    I de Waziers, P H Cugnenc, C S Yang, J P Leroux and P H Beaune
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 387-394;
  • You have access
    Muscarine depolarizes rat substantia nigra zona compacta and ventral tegmental neurons in vitro through M1-like receptors.
    M G Lacey, P Calabresi and R A North
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 395-400;
  • You have access
    Attenuation of opioid receptor activity by phorbol esters in neuroblastoma x glioma NG108-15 hybrid cells.
    A K Louie, E S Bass, J Zhan, P Y Law and H H Loh
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 401-407;
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    Role of imidazole receptors in the vasodepressor response to clonidine analogs in the rostral ventrolateral medulla.
    P Ernsberger, R Giuliano, R N Willette and D J Reis
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 408-418;
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    Cross-linking of human [125I]beta-endorphin to opioid receptors in rat striatal membranes: biochemical evidence for the existence of a mu/delta opioid receptor complex.
    A N Schoffelmeer, Y H Yao, T L Gioannini, J M Hiller, D Ofri, B P Roques and E J Simon
    Journal of Pharmacology and Experimental Therapeutics April 1990, 253 (1) 419-426;
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Journal of Pharmacology and Experimental Therapeutics
Vol. 253, Issue 1
1 Apr 1990
  • Table of Contents
  • Table of Contents (PDF)
  • Index by author
  • Editorial Board (PDF)
  • Front Matter (PDF)
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  • Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.
  • Functional Selectivity and Classical Concepts of Quantitative Pharmacology
  • Abl Protein-Tyrosine Kinase Inhibitor STI571 Inhibits In Vitro Signal Transduction Mediated by c-Kit and Platelet-Derived Growth Factor Receptors
  • The Prediction of Human Pharmacokinetic Parameters from Preclinical and In Vitro Metabolism Data
  • A METHOD FOR DETERMINING LOSS OF PAIN SENSATION
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