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Abstract

Suicide inactivation of cytochrome P-450 by methoxsalen. Evidence for the covalent binding of a reactive intermediate to the protein moiety.

G Labbe, V Descatoire, P Beaune, P Letteron, D Larrey and D Pessayre
Journal of Pharmacology and Experimental Therapeutics September 1989, 250 (3) 1034-1042;

Article Information

vol. 250 no. 3 1034-1042
PubMed 
2506333
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Published online September 1, 1989.

Author Information

  1. G Labbe,
  2. V Descatoire,
  3. P Beaune,
  4. P Letteron,
  5. D Larrey and
  6. D Pessayre
  1. Unité de Recherches de Physiopathologie Hépatique (INSERM U24), Hôpital Beaujon, Clichy, France.

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    Abstract

    Suicide inactivation of cytochrome P-450 by methoxsalen. Evidence for the covalent binding of a reactive intermediate to the protein moiety.

    G Labbe, V Descatoire, P Beaune, P Letteron, D Larrey and D Pessayre
    Journal of Pharmacology and Experimental Therapeutics September 1, 1989, 250 (3) 1034-1042;
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