Journal of Pharmacology and Experimental Therapeutics: 250 (1)

July 01, 1989; Volume 250,Issue 1

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Potency of infused spinal antinociceptive agents is inversely related to magnitude of tolerance after continuous infusion.
C W Stevens and T L Yaksh

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 1-8;
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Defective modulation of noradrenergic neurotransmission by endogenous prostaglandins in aging spontaneously hypertensive rats.
E K Jackson

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 9-21;
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PD 122860: a novel dihydropyridine with sodium channel stimulating and calcium channel blocking properties.
S J Haleen, R P Steffen, I Sircar, T C Major, M D Taylor, T A Pugsley and R E Weishaar

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 22-30;
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Studies defining minimal receptor domains for angiotensin II.
R G Pendleton, G Gessner and E Horner

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 31-36;
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Serotonin agonists inhibit synaptic potentials in the rat locus ceruleus in vitro via 5-hydroxytryptamine1A and 5-hydroxytryptamine1B receptors.
D H Bobker and J T Williams

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 37-43;
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Evidence that prostaglandins can contract the rat aorta via a novel protein kinase C-dependent mechanism.
R J Heaslip and B D Sickels

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 44-51;
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Selective 5-hydroxytryptamine2 antagonists have antidepressant-like effects on differential-reinforcement-of-low-rate 72-second schedule.
G J Marek, A A Li and L S Seiden

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 52-59;
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Evidence for involvement of 5-hydroxytryptamine1 receptors in antidepressant-like drug effects on differential-reinforcement-of-low-rate 72-second behavior.
G J Marek, A A Li and L S Seiden

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 60-71;
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Different serotonin receptors mediate blood pressure, heart rate, plasma catecholamine and prolactin responses to m-chlorophenylpiperazine in conscious rats.
G Bagdy, K Szemeredi, B Kanyicska and D L Murphy

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 72-78;
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Adenosine receptor prodrugs: towards kidney-selective dialkylxanthines.
S Barone, P C Churchill and K A Jacobson

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 79-85;
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Catecholamine receptors regulating serotonin N-acetyltransferase activity and melatonin content of chicken retina and pineal gland: D2-dopamine receptors in retina and alpha-2 adrenergic receptors in pineal gland.
J Zawilska and P M Iuvone

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 86-92;
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Pulmonary extraction of propranolol in normal and oxygen-toxic sheep.
R E Howell, P N Lanken, J H Hansen-Flaschen, F R Haselton, S M Albelda and A P Fishman

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 93-99;
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Pharmacological profile of NPC 12626, a novel, competitive N-methyl-D-aspartate receptor antagonist.
J W Ferkany, D J Kyle, J Willets, W J Rzeszotarski, M E Guzewska, S R Ellenberger, S M Jones, A I Sacaan, L D Snell and S Borosky

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 100-109;
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Characterization of membrane-bound and soluble D2 receptors in canine caudate using [125I]IBZM.
B S Schonwetter, R R Luedtke, M P Kung, J Billings, H F Kung and P B Molinoff

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 110-116;
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Comparative antidopaminergic properties of thioridazine, mesoridazine and sulforidazine on the corpus striatum.
D M Niedzwiecki, L X Cubeddu and R B Mailman

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 117-125;
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Comparative anticholinergic properties of thioridazine, mesoridazine and sulforidazine.
D M Niedzwiecki, L X Cubeddu and R B Mailman

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 126-133;
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Kinetic and dynamic study of intravenous lorazepam: comparison with intravenous diazepam.
D J Greenblatt, B L Ehrenberg, J Gunderman, J M Scavone, N T Tai, J S Harmatz and R I Shader

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 134-140;
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Increased serotonin efflux by a partially oxidized serotonin: tryptamine-4,5-dione.
J C Chen, P B Crino, P W Schnepper, A C To and L Volicer

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 141-148;
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Polyaspartic acid protects against gentamicin nephrotoxicity in the rat.
L S Ramsammy, C Josepovitz, B P Lane and G J Kaloyanides

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 149-153;
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Aspirin acetylates fibrinogen and enhances fibrinolysis. Fibrinolytic effect is independent of changes in plasminogen activator levels.
T D Bjornsson, D E Schneider and H Berger

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 154-161;
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Guanine nucleotides are competitive inhibitors of N-methyl-D-aspartate at its receptor site both in vitro and in vivo.
B M Baron, M W Dudley, D R McCarty, F P Miller, I J Reynolds and C J Schmidt

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 162-169;
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Adenosine does not mediate the pulmonary vasodilator response of adenosine 5'-triphosphate in the feline pulmonary vascular bed.
C F Neely, P J Kadowitz, H Lippton, M Neiman and A L Hyman

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 170-176;
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Presynaptic activation of the spinal serotonergic system in the rat by phencyclidine in vitro.
Y Ohno and J E Warnick

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 177-183;
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Drug discrimination in human postaddicts: agonist-antagonist opioids.
K L Preston, G E Bigelow, W K Bickel and I A Liebson

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 184-196;
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Analgesic effects of phencyclidine-like drugs in rhesus monkeys.
C P France, A M Snyder and J H Woods

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 197-201;
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Changes in drinking activity, urine volume and urinary electrolyte excretion after intracerebroventricular administration of diisopropylfluorophosphate.
M D Dulaney, R W Rockhold, A C Porter, B Hoskins and I K Ho

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 202-209;
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Pharmacokinetic and pharmacodynamic evaluation of phencyclidine and its decadeutero variant.
A K Cho, M Hiramatsu, R N Pechnick and E Di Stefano

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 210-215;
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Intraperitoneal endotoxin but not protein malnutrition shifts d-tubocurarine dose-response curves in mouse gastrocnemius muscle.
J F Tomera and J Martyn

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 216-220;
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Structural specificity of mechanisms controlling the hepatic uptake and biliary output of methotrexate in the rat.
J C Deutsch and J F Kolhouse

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 221-226;
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Preclinical studies on quinelorane, a potent and highly selective D2-dopaminergic agonist.
M M Foreman, R W Fuller, M D Hynes, J S Gidda, C L Nichols, J M Schaus, E C Kornfeld and J A Clemens

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 227-235;
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Phosphatidic acid phosphatase in neonatal rat lung: effects of prenatal dexamethasone or terbutaline treatment on basal activity and on responsiveness to beta adrenergic stimulation.
E M Kudlacz, H A Navarro and T A Slotkin

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 236-240;
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Characterization of the discriminative stimulus effects of physostigmine in the rat.
K W Locke, B Gorney, M Cornfeldt and S Fielding

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 241-246;
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Vulnerability of the thick ascending limb to glutathione depletion in rat kidney: effects of diuretics and indomethacin.
A M Torres, J V Rodriguez and M M Elías

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 247-253;
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Potentiation of para-hydroxyamphetamine-induced head-twitch response by inhibition of monoamine oxidase type A in the brain.
T Tadano, S Satoh, N Satoh, K Kisara, Y Arai, S K Kim and H Kinemuchi

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 254-260;
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In vitro and in vivo comparison of two K+ channel openers, diazoxide and cromakalim, and their inhibition by glibenclamide.
U Quast and N S Cook

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 261-271;
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Potent stimulation of myofilament force and adenosine triphosphatase activity of canine cardiac muscle through a direct enhancement of troponin C Ca++ binding by MCI-154, a novel cardiotonic agent.
Y Kitada, M Kobayashi, A Narimatsu and Y Ohizumi

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 272-277;
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Activation of ATP-sensitive outward K+ current by nicorandil (2-nicotinamidoethyl nitrate) in isolated ventricular myocytes.
M Hiraoka and Z Fan

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 278-285;
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Calmodulin and free oxygen radicals interaction with steady-state calcium accumulation and passive calcium permeability of cardiac sarcoplasmic reticulum.
E Okabe, M Sugihara, K Tanaka, H Sasaki and H Ito

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 286-292;
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Evidence for the existence and ionic modulation of platelet-activating factor receptors mediating degranulatory responses in human polymorphonuclear leukocytes.
O Marquis, C Robaut and I Cavero

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 293-300;
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Multispecificity of Na+-dependent taurocholate uptake in basolateral (sinusoidal) rat liver plasma membrane vesicles.
B Zimmerli, J Valantinas and P J Meier

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 301-308;
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Characterization of muscarinic receptors in human, guinea pig and rat lung.
J P Gies, C Bertrand, P Vanderheyden, F Waeldele, P Dumont, G Pauli and Y Landry

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 309-315;
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Relationship between biotransformation of glyceryl trinitrate and cyclic GMP accumulation in various cultured cell lines.
B M Bennett, D C Leitman, H Schröder, J H Kawamoto, K Nakatsu and F Murad

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 316-323;
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Transport of cefodizime, a novel third generation cephalosporin antibiotic, in isolated rat choroid plexus.
T Nohjoh, H Suzuki, Y Sawada, Y Sugiyama, T Iga and M Hanano

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 324-328;
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Activation of rat peritoneal mast cells by substance P and mastoparan.
M Mousli, C Bronner, J L Bueb, E Tschirhart, J P Gies and Y Landry

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 329-335;
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Modulation of embryonic glutathione reductase and phenytoin teratogenicity by 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU).
M Wong and P G Wells

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 336-342;
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Guanine nucleotide binding proteins may modulate gating of calcium channels in vascular smooth muscle. I. Studies with fluoride.
Y Y Zeng, C G Benishin and P K Pang

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 343-351;
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Guanine nucleotide binding proteins may modulate gating of calcium channels in vascular smooth muscle. II. Studies with guanosine 5'-(gamma)triphosphate.
Y Y Zeng, C G Benishin and P K Pang

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 352-357;
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Behavioral evidence for the role of noradrenaline in the putative anxiogenic actions of the inverse benzodiazepine receptor agonist methyl-4-ethyl-6,7-dimethoxy-beta-carboline-3-carboxylate.
X M Yang, Z P Luo and J H Zhou

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 358-363;
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Alpha adrenoceptor stimulation reduces outward currents in rat ventricular myocytes.
U Ravens, X L Wang and E Wettwer

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 364-370;
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Tolerance to respiratory actions of sufentanil: functional tolerance and route-dependent differential tolerance.
F J Ayesta and J Flórez

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 371-378;
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Evidence for two populations of 5-hydroxytryptamine receptors in dog basilar artery.
M Frenken

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 379-387;
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Calcium-independent activation of contractile apparatus in smooth muscle by calyculin-A.
H Ishihara, H Ozaki, K Sato, M Hori, H Karaki, S Watabe, Y Kato, N Fusetani, K Hashimoto and D Uemura

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 388-396;
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Electrophysiologic effects of ketanserin on canine Purkinje fibers, ventricular myocardium and the intact heart.
A Zaza, G Malfatto and M R Rosen

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 397-405;
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Quantitative histologic analysis of local anesthetic-induced injury to rat sciatic nerve.
M W Kalichman, H C Powell and R R Myers

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 406-413;
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Thiazide diuretic receptors: autoradiographic localization in rat kidney with [3H]metolazone.
K Beaumont, D A Vaughn and D P Healy

Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 414-419;

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