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Journal of Pharmacology and Experimental Therapeutics

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Table of Contents

July 01, 1989; Volume 250,Issue 1
  • You have access
    Potency of infused spinal antinociceptive agents is inversely related to magnitude of tolerance after continuous infusion.
    C W Stevens and T L Yaksh
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 1-8;
  • You have access
    Defective modulation of noradrenergic neurotransmission by endogenous prostaglandins in aging spontaneously hypertensive rats.
    E K Jackson
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 9-21;
  • You have access
    PD 122860: a novel dihydropyridine with sodium channel stimulating and calcium channel blocking properties.
    S J Haleen, R P Steffen, I Sircar, T C Major, M D Taylor, T A Pugsley and R E Weishaar
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 22-30;
  • You have access
    Studies defining minimal receptor domains for angiotensin II.
    R G Pendleton, G Gessner and E Horner
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 31-36;
  • You have access
    Serotonin agonists inhibit synaptic potentials in the rat locus ceruleus in vitro via 5-hydroxytryptamine1A and 5-hydroxytryptamine1B receptors.
    D H Bobker and J T Williams
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 37-43;
  • You have access
    Evidence that prostaglandins can contract the rat aorta via a novel protein kinase C-dependent mechanism.
    R J Heaslip and B D Sickels
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 44-51;
  • You have access
    Selective 5-hydroxytryptamine2 antagonists have antidepressant-like effects on differential-reinforcement-of-low-rate 72-second schedule.
    G J Marek, A A Li and L S Seiden
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 52-59;
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    Evidence for involvement of 5-hydroxytryptamine1 receptors in antidepressant-like drug effects on differential-reinforcement-of-low-rate 72-second behavior.
    G J Marek, A A Li and L S Seiden
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 60-71;
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    Different serotonin receptors mediate blood pressure, heart rate, plasma catecholamine and prolactin responses to m-chlorophenylpiperazine in conscious rats.
    G Bagdy, K Szemeredi, B Kanyicska and D L Murphy
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 72-78;
  • You have access
    Adenosine receptor prodrugs: towards kidney-selective dialkylxanthines.
    S Barone, P C Churchill and K A Jacobson
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 79-85;
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    Catecholamine receptors regulating serotonin N-acetyltransferase activity and melatonin content of chicken retina and pineal gland: D2-dopamine receptors in retina and alpha-2 adrenergic receptors in pineal gland.
    J Zawilska and P M Iuvone
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 86-92;
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    Pulmonary extraction of propranolol in normal and oxygen-toxic sheep.
    R E Howell, P N Lanken, J H Hansen-Flaschen, F R Haselton, S M Albelda and A P Fishman
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 93-99;
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    Pharmacological profile of NPC 12626, a novel, competitive N-methyl-D-aspartate receptor antagonist.
    J W Ferkany, D J Kyle, J Willets, W J Rzeszotarski, M E Guzewska, S R Ellenberger, S M Jones, A I Sacaan, L D Snell and S Borosky
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 100-109;
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    Characterization of membrane-bound and soluble D2 receptors in canine caudate using [125I]IBZM.
    B S Schonwetter, R R Luedtke, M P Kung, J Billings, H F Kung and P B Molinoff
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 110-116;
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    Comparative antidopaminergic properties of thioridazine, mesoridazine and sulforidazine on the corpus striatum.
    D M Niedzwiecki, L X Cubeddu and R B Mailman
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 117-125;
  • You have access
    Comparative anticholinergic properties of thioridazine, mesoridazine and sulforidazine.
    D M Niedzwiecki, L X Cubeddu and R B Mailman
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 126-133;
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    Kinetic and dynamic study of intravenous lorazepam: comparison with intravenous diazepam.
    D J Greenblatt, B L Ehrenberg, J Gunderman, J M Scavone, N T Tai, J S Harmatz and R I Shader
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 134-140;
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    Increased serotonin efflux by a partially oxidized serotonin: tryptamine-4,5-dione.
    J C Chen, P B Crino, P W Schnepper, A C To and L Volicer
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 141-148;
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    Polyaspartic acid protects against gentamicin nephrotoxicity in the rat.
    L S Ramsammy, C Josepovitz, B P Lane and G J Kaloyanides
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 149-153;
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    Aspirin acetylates fibrinogen and enhances fibrinolysis. Fibrinolytic effect is independent of changes in plasminogen activator levels.
    T D Bjornsson, D E Schneider and H Berger
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 154-161;
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    Guanine nucleotides are competitive inhibitors of N-methyl-D-aspartate at its receptor site both in vitro and in vivo.
    B M Baron, M W Dudley, D R McCarty, F P Miller, I J Reynolds and C J Schmidt
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 162-169;
  • You have access
    Adenosine does not mediate the pulmonary vasodilator response of adenosine 5'-triphosphate in the feline pulmonary vascular bed.
    C F Neely, P J Kadowitz, H Lippton, M Neiman and A L Hyman
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 170-176;
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    Presynaptic activation of the spinal serotonergic system in the rat by phencyclidine in vitro.
    Y Ohno and J E Warnick
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 177-183;
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    Drug discrimination in human postaddicts: agonist-antagonist opioids.
    K L Preston, G E Bigelow, W K Bickel and I A Liebson
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 184-196;
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    Analgesic effects of phencyclidine-like drugs in rhesus monkeys.
    C P France, A M Snyder and J H Woods
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 197-201;
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    Changes in drinking activity, urine volume and urinary electrolyte excretion after intracerebroventricular administration of diisopropylfluorophosphate.
    M D Dulaney, R W Rockhold, A C Porter, B Hoskins and I K Ho
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 202-209;
  • You have access
    Pharmacokinetic and pharmacodynamic evaluation of phencyclidine and its decadeutero variant.
    A K Cho, M Hiramatsu, R N Pechnick and E Di Stefano
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 210-215;
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    Intraperitoneal endotoxin but not protein malnutrition shifts d-tubocurarine dose-response curves in mouse gastrocnemius muscle.
    J F Tomera and J Martyn
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 216-220;
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    Structural specificity of mechanisms controlling the hepatic uptake and biliary output of methotrexate in the rat.
    J C Deutsch and J F Kolhouse
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 221-226;
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    Preclinical studies on quinelorane, a potent and highly selective D2-dopaminergic agonist.
    M M Foreman, R W Fuller, M D Hynes, J S Gidda, C L Nichols, J M Schaus, E C Kornfeld and J A Clemens
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 227-235;
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    Phosphatidic acid phosphatase in neonatal rat lung: effects of prenatal dexamethasone or terbutaline treatment on basal activity and on responsiveness to beta adrenergic stimulation.
    E M Kudlacz, H A Navarro and T A Slotkin
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 236-240;
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    Characterization of the discriminative stimulus effects of physostigmine in the rat.
    K W Locke, B Gorney, M Cornfeldt and S Fielding
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 241-246;
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    Vulnerability of the thick ascending limb to glutathione depletion in rat kidney: effects of diuretics and indomethacin.
    A M Torres, J V Rodriguez and M M Elías
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 247-253;
  • You have access
    Potentiation of para-hydroxyamphetamine-induced head-twitch response by inhibition of monoamine oxidase type A in the brain.
    T Tadano, S Satoh, N Satoh, K Kisara, Y Arai, S K Kim and H Kinemuchi
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 254-260;
  • You have access
    In vitro and in vivo comparison of two K+ channel openers, diazoxide and cromakalim, and their inhibition by glibenclamide.
    U Quast and N S Cook
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 261-271;
  • You have access
    Potent stimulation of myofilament force and adenosine triphosphatase activity of canine cardiac muscle through a direct enhancement of troponin C Ca++ binding by MCI-154, a novel cardiotonic agent.
    Y Kitada, M Kobayashi, A Narimatsu and Y Ohizumi
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 272-277;
  • You have access
    Activation of ATP-sensitive outward K+ current by nicorandil (2-nicotinamidoethyl nitrate) in isolated ventricular myocytes.
    M Hiraoka and Z Fan
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 278-285;
  • You have access
    Calmodulin and free oxygen radicals interaction with steady-state calcium accumulation and passive calcium permeability of cardiac sarcoplasmic reticulum.
    E Okabe, M Sugihara, K Tanaka, H Sasaki and H Ito
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 286-292;
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    Evidence for the existence and ionic modulation of platelet-activating factor receptors mediating degranulatory responses in human polymorphonuclear leukocytes.
    O Marquis, C Robaut and I Cavero
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 293-300;
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    Multispecificity of Na+-dependent taurocholate uptake in basolateral (sinusoidal) rat liver plasma membrane vesicles.
    B Zimmerli, J Valantinas and P J Meier
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 301-308;
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    Characterization of muscarinic receptors in human, guinea pig and rat lung.
    J P Gies, C Bertrand, P Vanderheyden, F Waeldele, P Dumont, G Pauli and Y Landry
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 309-315;
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    Relationship between biotransformation of glyceryl trinitrate and cyclic GMP accumulation in various cultured cell lines.
    B M Bennett, D C Leitman, H Schröder, J H Kawamoto, K Nakatsu and F Murad
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 316-323;
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    Transport of cefodizime, a novel third generation cephalosporin antibiotic, in isolated rat choroid plexus.
    T Nohjoh, H Suzuki, Y Sawada, Y Sugiyama, T Iga and M Hanano
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 324-328;
  • You have access
    Activation of rat peritoneal mast cells by substance P and mastoparan.
    M Mousli, C Bronner, J L Bueb, E Tschirhart, J P Gies and Y Landry
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 329-335;
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    Modulation of embryonic glutathione reductase and phenytoin teratogenicity by 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU).
    M Wong and P G Wells
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 336-342;
  • You have access
    Guanine nucleotide binding proteins may modulate gating of calcium channels in vascular smooth muscle. I. Studies with fluoride.
    Y Y Zeng, C G Benishin and P K Pang
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 343-351;
  • You have access
    Guanine nucleotide binding proteins may modulate gating of calcium channels in vascular smooth muscle. II. Studies with guanosine 5'-(gamma)triphosphate.
    Y Y Zeng, C G Benishin and P K Pang
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 352-357;
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    Behavioral evidence for the role of noradrenaline in the putative anxiogenic actions of the inverse benzodiazepine receptor agonist methyl-4-ethyl-6,7-dimethoxy-beta-carboline-3-carboxylate.
    X M Yang, Z P Luo and J H Zhou
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 358-363;
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    Alpha adrenoceptor stimulation reduces outward currents in rat ventricular myocytes.
    U Ravens, X L Wang and E Wettwer
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 364-370;
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    Tolerance to respiratory actions of sufentanil: functional tolerance and route-dependent differential tolerance.
    F J Ayesta and J Flórez
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 371-378;
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    Evidence for two populations of 5-hydroxytryptamine receptors in dog basilar artery.
    M Frenken
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 379-387;
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    Calcium-independent activation of contractile apparatus in smooth muscle by calyculin-A.
    H Ishihara, H Ozaki, K Sato, M Hori, H Karaki, S Watabe, Y Kato, N Fusetani, K Hashimoto and D Uemura
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 388-396;
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    Electrophysiologic effects of ketanserin on canine Purkinje fibers, ventricular myocardium and the intact heart.
    A Zaza, G Malfatto and M R Rosen
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 397-405;
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    Quantitative histologic analysis of local anesthetic-induced injury to rat sciatic nerve.
    M W Kalichman, H C Powell and R R Myers
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 406-413;
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    Thiazide diuretic receptors: autoradiographic localization in rat kidney with [3H]metolazone.
    K Beaumont, D A Vaughn and D P Healy
    Journal of Pharmacology and Experimental Therapeutics July 1989, 250 (1) 414-419;
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In this issue

Journal of Pharmacology and Experimental Therapeutics
Vol. 250, Issue 1
1 Jul 1989
  • Table of Contents
  • Index by author
  • Back Matter (PDF)
  • Editorial Board (PDF)
  • Front Matter (PDF)
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  • Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.
  • Functional Selectivity and Classical Concepts of Quantitative Pharmacology
  • Abl Protein-Tyrosine Kinase Inhibitor STI571 Inhibits In Vitro Signal Transduction Mediated by c-Kit and Platelet-Derived Growth Factor Receptors
  • The Prediction of Human Pharmacokinetic Parameters from Preclinical and In Vitro Metabolism Data
  • A METHOD FOR DETERMINING LOSS OF PAIN SENSATION
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