Journal of Pharmacology and Experimental Therapeutics: 249 (3)

June 01, 1989; Volume 249,Issue 3

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Effects of ICI 169,369, a selective serotonin2 antagonist, in electrophysiological tests predictive of antipsychotic activity.
J M Goldstein, L C Litwin, E B Sutton and J B Malick

Journal of Pharmacology and Experimental Therapeutics June 1989, 249 (3) 673-680;
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Dopamine and neurotensin storage in colocalized and noncolocalized neuronal populations.
A J Bean, T E Adrian, I M Modlin and R H Roth

Journal of Pharmacology and Experimental Therapeutics June 1989, 249 (3) 681-687;
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Studies on the mechanism of hypoglycemia induced by intrathecal morphine: dissociation from behavioral effects, effects of tolerance and depletion of liver glycogen.
F Lux, Y H Han, D A Brase and W L Dewey

Journal of Pharmacology and Experimental Therapeutics June 1989, 249 (3) 688-693;
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Synergistic alpha-1 and alpha-2 adrenergic stimulation of rat proximal nephron Na+/H+ exchange.
F A Gesek, E J Cragoe and J W Strandhoy

Journal of Pharmacology and Experimental Therapeutics June 1989, 249 (3) 694-700;
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Repeated swim stress alters brain benzodiazepine receptors measured in vivo.
R Weizman, A Weizman, K A Kook, F Vocci, S I Deutsch and S M Paul

Journal of Pharmacology and Experimental Therapeutics June 1989, 249 (3) 701-707;
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Anticonvulsant activities of 1-phenylcyclohexylamine and its conformationally restricted analog 1,1-pentamethylenetetrahydroisoquinoline.
M A Rogawski, A Thurkauf, S Yamaguchi, K C Rice, A E Jacobson and M V Mattson

Journal of Pharmacology and Experimental Therapeutics June 1989, 249 (3) 708-712;
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3,4-Methylenedioxymethamphetamine ("ecstasy") selectively destroys brain serotonin terminals in rhesus monkeys.
T R Insel, G Battaglia, J N Johannessen, S Marra and E B De Souza

Journal of Pharmacology and Experimental Therapeutics June 1989, 249 (3) 713-720;
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Baclofen has a proepileptic effect in the rat dentate gyrus.
D D Mott, A C Bragdon, D V Lewis and W A Wilson

Journal of Pharmacology and Experimental Therapeutics June 1989, 249 (3) 721-725;
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S-nitrosocaptopril. I. Molecular characterization and effects on the vasculature and on platelets.
J Loscalzo, D Smick, N Andon and J Cooke

Journal of Pharmacology and Experimental Therapeutics June 1989, 249 (3) 726-729;
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S-nitrosocaptopril. II. Effects on vascular reactivity.
J P Cooke, N Andon and J Loscalzo

Journal of Pharmacology and Experimental Therapeutics June 1989, 249 (3) 730-734;
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Alterations of spontaneous and evoked release of acetylcholine during dithiobiuret-induced neuromuscular weakness.
W D Atchison

Journal of Pharmacology and Experimental Therapeutics June 1989, 249 (3) 735-743;
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Entry of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine into the rat brain.
N J Riachi, J C LaManna and S I Harik

Journal of Pharmacology and Experimental Therapeutics June 1989, 249 (3) 744-748;
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Substitution and antagonism in rats trained to discriminate (+)-N-allylnormetazocine from saline.
R L Balster

Journal of Pharmacology and Experimental Therapeutics June 1989, 249 (3) 749-756;
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Role of medullary plasma flow in the attenuated furosemide response in indomethacin-treated rats.
K A Kirchner

Journal of Pharmacology and Experimental Therapeutics June 1989, 249 (3) 757-761;
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Multiplicative interaction between intrathecally and intracerebroventricularly administered mu opioid agonists but limited interactions between delta and kappa agonists for antinociception in mice.
S C Roerig and J M Fujimoto

Journal of Pharmacology and Experimental Therapeutics June 1989, 249 (3) 762-768;
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Acute extrapyramidal syndrome in Cebus monkeys: development mediated by dopamine D2 but not D1 receptors.
V L Coffin, M B Latranyi and R E Chipkin

Journal of Pharmacology and Experimental Therapeutics June 1989, 249 (3) 769-774;
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Characterization of the adenosine receptor in cultured embryonic chick atrial myocytes: coupling to modulation of contractility and adenylate cyclase activity and identification by direct radioligand binding.
B T Liang

Journal of Pharmacology and Experimental Therapeutics June 1989, 249 (3) 775-784;
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Cholinergic contraction to field stimulation in coronary arteries of cattle.
S Kalsner and M Quillan

Journal of Pharmacology and Experimental Therapeutics June 1989, 249 (3) 785-789;
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Electrophysiological characteristics and pharmacological responsiveness of midbrain dopaminergic neurons of the aged rat.
A S Freeman, M D Kelland, C Rouillard and L A Chiodo

Journal of Pharmacology and Experimental Therapeutics June 1989, 249 (3) 790-797;
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Changes in the muscarinic cholinergic receptors in the hippocampus of rats exposed to ethyl alcohol during the brain growth spurt.
S J Kelly, A C Black and J R West

Journal of Pharmacology and Experimental Therapeutics June 1989, 249 (3) 798-804;
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Antagonism of leukotriene C4, leukotriene D4 and leukotriene E4 vasoconstrictor responses in the conscious rat with the peptidoleukotriene receptor antagonist SK&F 104353: evidence for leukotriene D4 receptor heterogeneity.
E F Smith, M J Slivjak, R D Eckardt and J F Newton

Journal of Pharmacology and Experimental Therapeutics June 1989, 249 (3) 805-811;
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Role of cyclic AMP-dependent protein kinase in the diminished beta adrenergic responsiveness of vascular smooth muscle with increasing age.
T A Deisher, S Mankani and B B Hoffman

Journal of Pharmacology and Experimental Therapeutics June 1989, 249 (3) 812-819;
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Structure-activity study of the mechanism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neurotoxicity. I. Evaluation of the biological activity of MPTP analogs.
S K Youngster, P K Sonsalla, B A Sieber and R E Heikkila

Journal of Pharmacology and Experimental Therapeutics June 1989, 249 (3) 820-828;
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Structure-activity study of the mechanism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neurotoxicity. II. Evaluation of the biological activity of the pyridinium metabolites formed from the monoamine oxidase-catalyzed oxidation of MPTP analogs.
S K Youngster, W J Nicklas and R E Heikkila

Journal of Pharmacology and Experimental Therapeutics June 1989, 249 (3) 829-835;
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Specificity of the activation of [3H]hemicholinium-3 binding by phospholipase A2.
K Yamada, M D Saltarelli and J T Coyle

Journal of Pharmacology and Experimental Therapeutics June 1989, 249 (3) 836-842;
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Muscarinic receptors: relationships among phosphoinositide breakdown, adenylate cyclase inhibition, in vitro detrusor muscle contractions and in vivo cystometrogram studies in guinea pig bladder.
L Noronha-Blob, V Lowe, A Patton, B Canning, D Costello and W J Kinnier

Journal of Pharmacology and Experimental Therapeutics June 1989, 249 (3) 843-851;
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Dimethyl sulfoxide affects water flow through a nonosmolar action.
S Sabatini, J C Wharton, H K Lim and N A Kurtzman

Journal of Pharmacology and Experimental Therapeutics June 1989, 249 (3) 852-857;
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Phorbol dibutyrate inhibits release and action of endothelium-derived relaxing factor(s) in canine blood vessels.
G M Rubanyi, D Desiderio, A Luisi, A Johns and E J Sybertz

Journal of Pharmacology and Experimental Therapeutics June 1989, 249 (3) 858-863;
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Mu- and delta-opioid receptor-mediated inhibition of adenylate cyclase activity stimulated by released endogenous dopamine in rat neostriatal slices; demonstration of potent delta-agonist activity of bremazocine.
M H Heijna, F Hogenboom, P S Portoghese, A H Mulder and A N Schoffelmeer

Journal of Pharmacology and Experimental Therapeutics June 1989, 249 (3) 864-868;
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Zonal compartmentation of perfused rat liver: plasma reappearance of rhodamine B explained.
I Braakman, G M Groothuis and D K Meijer

Journal of Pharmacology and Experimental Therapeutics June 1989, 249 (3) 869-873;
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Stereoselectivity of glutathione conjugation: blood elimination of alpha-bromoisovalerylurea enantiomers and biliary excretion of the conjugates in unanesthetized normal or congenitally jaundiced rats.
M Polhuijs, F Kuipers, R J Vonk and G J Mulder

Journal of Pharmacology and Experimental Therapeutics June 1989, 249 (3) 874-878;
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Pharmacological properties of the receptor(s) involved in the 5-hydroxytryptamine-induced contraction of the feline middle cerebral artery.
E Hamel, J P Robert, A R Young and E T MacKenzie

Journal of Pharmacology and Experimental Therapeutics June 1989, 249 (3) 879-889;
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Involvement of endothelial cells in relaxation and contraction responses of the aorta to isoproterenol in naive and streptozotocin-induced diabetic rats.
K Kamata, N Miyata and Y Kasuya

Journal of Pharmacology and Experimental Therapeutics June 1989, 249 (3) 890-894;
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Effect of forskolin on cytosolic Ca++ level and contraction in vascular smooth muscle.
A Abe and H Karaki

Journal of Pharmacology and Experimental Therapeutics June 1989, 249 (3) 895-900;
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Transport of vasopressin fragments across the blood-brain barrier: in vitro studies using monolayer cultures of bovine brain endothelial cells.
J B van Bree, A G de Boer, J C Verhoef, M Danhof and D D Breimer

Journal of Pharmacology and Experimental Therapeutics June 1989, 249 (3) 901-905;
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Neocarzinostatin induces neuronal morphology of mouse neuroblastoma in culture.
N F Schor

Journal of Pharmacology and Experimental Therapeutics June 1989, 249 (3) 906-910;
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Species differences in the localization and number of CNS beta adrenergic receptors: rat versus guinea pig.
R M Booze, E A Crisostomo and J N Davis

Journal of Pharmacology and Experimental Therapeutics June 1989, 249 (3) 911-920;
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Epidermal cytochrome P-450: immunochemical characterization of isoform induced by topical application of 3-methylcholanthrene to neonatal rat.
W A Khan, S S Park, H V Gelboin, D R Bickers and H Mukhtar

Journal of Pharmacology and Experimental Therapeutics June 1989, 249 (3) 921-927;
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Fenfluramine selectively and differentially decreases the density of serotonergic nerve terminals in rat brain: evidence from immunocytochemical studies.
N M Appel, J F Contrera and E B De Souza

Journal of Pharmacology and Experimental Therapeutics June 1989, 249 (3) 928-943;
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Mechanism of toxicity of an experimental bidentate phosphine gold complexed antineoplastic agent in isolated rat hepatocytes.
P F Smith, G D Hoke, D W Alberts, P J Bugelski, S Lupo, C K Mirabelli and G F Rush

Journal of Pharmacology and Experimental Therapeutics June 1989, 249 (3) 944-950;

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